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List of works by Yoon K Loke

"The computer says no" Are there tools and algorithms that will help us stop potentially inappropriate medications?

scientific article published on 26 August 2020

A comparison of three different sources of data in assessing the frequencies of adverse reactions to amiodarone

scientific article

A safety review and meta-analyses of bevacizumab and ranibizumab: off-label versus goldstandard

scientific article published on 3 August 2012

Access and non-access site bleeding after percutaneous coronary intervention and risk of subsequent mortality and major adverse cardiovascular events: systematic review and meta-analysis.

scientific article published on April 2015

Adverse drug reactions: keeping up to date

scientific article

Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study

scientific article published on 24 November 2020

Air travel and venous thrombosis: how much help might aspirin be?

scientific article (publication date: 20 September 2002)

An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease

scientific article

Anticholinergic Burden Measures Predict Older People's Physical Function and Quality of Life: A Systematic Review

scientific article published on 21 July 2020

Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study

scientific article published on 21 October 2019

Anticholinergic drugs and incident dementia, mild cognitive impairment and cognitive decline: a meta-analysis

scientific article published on 29 June 2020

Anticholinergic drugs and risk of dementia: case-control study.

scientific article

Appetite suppressants and valvular heart disease - a systematic review

scientific article

Association between different methods of assessing blood pressure variability and incident cardiovascular disease, cardiovascular mortality and all-cause mortality: a systematic review

scientific article published on 01 February 2020

Asthma Breathomics and Biomedium Consideration

scientific article published on 01 May 2018

Asthma breathomics-promising biomarkers in need of validation

scientific article

Authors’ response

Bariatric surgery and its impact on cardiovascular disease and mortality: a systematic review and meta-analysis.

scientific article

Benefits and harms of extending the duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stents: a meta-analysis.

scientific article published on 2 March 2014

Biomarkers in adult asthma: a systematic review of 8-isoprostane in exhaled breath condensate.

scientific article published on 19 January 2017

Bleeding risk in patients prescribed dual antiplatelet therapy and triple therapy after coronary interventions: the ADAPTT retrospective population-based cohort studies

scientific article published in 2023

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis

scientific article

Can cardiovascular risk management be improved by shared care with general practice to prevent cognitive decline following stroke/TIA? A feasibility randomised controlled trial (SERVED memory)

scientific article published on 17 September 2020

Challenges in evaluating surgical innovation

scientific article

Changes in antiplatelet use prior to incident ischaemic stroke over 7 years in a UK centre and the association with stroke subtype.

scientific article published on 05 July 2013

Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled trials

scientific article

Closure methods of the appendix stump for complications during laparoscopic appendectomy

scientific article published on 13 November 2017

Cognitive decline associated with anticholinergics, benzodiazepines, and Z-drugs: findings from The Irish Longitudinal Study on Ageing (TILDA)

scientific article published on 03 December 2020

Comparative coronary risks of apixaban, rivaroxaban and dabigatran: a meta-analysis and adjusted indirect comparison

scientific article

Comparison of pooled risk estimates for adverse effects from different observational study designs: methodological overview

scientific article (publication date: 2013)

Comparison of search strategies in systematic reviews of adverse effects to other systematic reviews

scientific article published on 23 April 2014

Comprehensive evaluations of the adverse effects of drugs: importance of appropriate study selection and data sources

scientific article

Critical Overview on the Benefits and Harms of Aspirin.

scientific article

Determining the reporting quality of RCTs in clinical pharmacology

scientific article published on July 2004

Dietary components and risk of cardiovascular disease and all-cause mortality: a review of evidence from meta-analyses

scientific article published on 11 April 2019

Does anybody read "evidence-based" articles?

scientific article

Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis.

scientific article published on 17 December 2007

Drug safety assessment in clinical trials: methodological challenges and opportunities

scientific article published on 20 August 2012

Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke

scientific article published on 30 July 2018

Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke: pooled analysis of randomized trials.

scientific article published on 26 February 2015

Evaluation and stages of surgical innovations

scientific article published in The Lancet

Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies

scientific article

Habitual chocolate consumption and risk of cardiovascular disease among healthy men and women.

scientific article published on 15 June 2015

History of Benzodiazepine Prescriptions and Risk of Dementia: Possible Bias Due to Prevalent Users and Covariate Measurement Timing in a Nested Case-Control Study

scientific article published on 01 July 2019

Identifying systematic reviews of the adverse effects of health care interventions.

scientific article

Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta-Analysis

scientific article

Incidentally Raised Cardiac Troponin I Has a Worse Prognosis in Older Patients Compared to Those with Normal Cardiac Troponin I and Patients with Acute Coronary Syndrome: A Cohort Study

scientific article published on 24 March 2016

Inconsistency between direct and indirect comparisons of competing interventions: meta-epidemiological study

scientific article published on 16 August 2011

Increasing prevalence of anticholinergic medication use in older people in England over 20 years: cognitive function and ageing study I and II

scientific article published on 31 July 2020

Inhaled Corticosteroids in Patients With Chronic Obstructive Pulmonary Disease

scientific article published in The Journal of the American Medical Association

Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

scientific article

Interventions to Reduce Anticholinergic Burden in Adults Aged 65 and Older: A Systematic Review

scientific article published on 24 July 2019

Intravitreal bevacizumab (Avastin) versus ranibizumab (Lucentis) for the treatment of age-related macular degeneration: a safety review

scientific article

Is avoidance of hypoglycaemia a better target than HbA1C in older people with diabetes?

scientific article published on 30 August 2020

Is there evidence for biased reporting of published adverse effects data in pharmaceutical industry-funded studies?

scientific article

Issues relating to selective reporting when including non-randomized studies in systematic reviews on the effects of healthcare interventions

scientific article

Long-term Glycemic Variability and Risk of Adverse Outcomes: A Systematic Review and Meta-analysis.

scientific article

Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis

scientific article

Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease: a meta-analysis

scientific article published on February 2009

Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis

scientific article

Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis

scientific article published on 15 February 2011

Major bleeding after percutaneous coronary intervention and risk of subsequent mortality: a systematic review and meta-analysis

scientific article

Meta-Analysis of the Prognostic Impact of Anemia in Patients Undergoing Percutaneous Coronary Intervention.

scientific article

Meta-analyses of adverse effects data derived from randomised controlled trials as compared to observational studies: methodological overview

scientific article

Meta-analysis: Association between hypoglycaemia and serious adverse events in older patients

scientific article published on 17 March 2016

Meta-review: adverse effects of inhaled corticosteroids relevant to older patients

scientific article published on April 2014

Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: survey of published systematic reviews

scientific article published on 03 April 2009

Methods to Compare Adverse Events in Twitter to FAERS, Drug Information Databases, and Systematic Reviews: Proof of Concept with Adalimumab

scientific article published on 01 December 2018

Midregional proadrenomedullin for prognosis in community-acquired pneumonia: a systematic review

scientific article published in November 2014

Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials

scientific article

Most systematic reviews of adverse effects did not include unpublished data.

scientific article

Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use

scientific article published on 27 February 2020

No surgical innovation without evaluation: the IDEAL recommendations

scientific article published in September 2009

Non-benzodiazepine hypnotic use for sleep disturbance in people aged over 55 years living with dementia: a series of cohort studies

scientific article published on 01 January 2021

Non-specific chest pain and subsequent serious cardiovascular readmissions

scientific article published on 02 April 2019

Nonspecific Chest Pain and 30-Day Unplanned Readmissions in the United States (From the Nationwide Readmission Database)

scientific article published on 25 January 2019

Oral direct-acting antivirals and the incidence or recurrence of hepatocellular carcinoma: a systematic review and meta-analysis

article

Outpatient Management of Severe COPD ⬇️

scientific article published on July 29, 2010

Overall similarity and consistency assessment scores are not sufficiently accurate for predicting discrepancy between direct and indirect comparison estimates

scientific article

Overview of systematic reviews of therapeutic ranges: methodologies and recommendations for practice.

scientific article

Overview: comprehensive and carefully constructed strategies are required when conducting searches for adverse effects data

scientific article published on 28 May 2019

PRISMA harms checklist: improving harms reporting in systematic reviews

scientific article published on February 2016

Pharmacist-led medication review: response to Silcock & Petty.

scientific article published on 16 July 2008

Physical activity and incidence of atrial fibrillation: a systematic review and meta-analysis.

scientific article

Poor reporting and inadequate searches were apparent in systematic reviews of adverse effects

scientific article published on 22 October 2007

Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis

scientific article published on 15 February 2016

Propensity score methods in real-world epidemiology: A practical guide for first-time users

scientific article published on 01 April 2020

Propofol infusion for paediatric sedation

scientific article

Propofol infusion for paediatric sedation

scientific article (publication date: 18 April 2012)

Protocol for a feasibility randomised controlled trial of Screening and Enhanced Risk management for Vascular Event-related Decline in Memory (SERVED Memory).

scientific article published on 28 November 2017

Quality of reporting in systematic reviews of adverse events: systematic review

scientific article

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

scientific article published on 12 October 2016

Relative effects of two different enoxaparin regimens as comparators against newer oral anticoagulants: meta-analysis and adjusted indirect comparison.

scientific article

Renal denervation and blood pressure reduction in resistant hypertension: a systematic review and meta-analysis.

scientific article

Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review

scientific article

Republished: Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications

article published in 2014

Response to Van De Sijpe et al.: Preventing medication-related harm: Perfect is the enemy of the good

scientific article published on 27 December 2020

Risk of acute urinary retention associated with inhaled anticholinergics in patients with chronic obstructive lung disease: systematic review.

scientific article

Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies

scientific article published on 20 May 2011

Risk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and update

scientific article

Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis

scientific article

Risk prediction models for mortality in community-acquired pneumonia: a systematic review

scientific article published on 21 October 2013

Risks associated with tiotropium in chronic obstructive pulmonary disease: overview of the evidence to date

scientific article

Room for improvement? A survey of the methods used in systematic reviews of adverse effects

scientific article

Safety of short-term dual antiplatelet therapy after drug-eluting stents: An updated meta-analysis with direct and adjusted indirect comparison of randomized control trials

scientific article published on 13 December 2014

Search strategies to identify information on adverse effects: a systematic review.

scientific article published on April 2009

Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews

scientific article

Sensitivity and precision of adverse effects search filters in MEDLINE and EMBASE: a case study of fractures with thiazolidinediones.

scientific article published on 19 December 2011

Some improvements are apparent in identifying adverse effects in systematic reviews from 1994 to 2011.

scientific article published on March 2013

Sources of information on adverse effects: a systematic review

scientific article published on September 2010

Statins and pancreatitis: a systematic review of observational studies and spontaneous case reports

scientific article published on January 2006

Statistical reporting of clinical pharmacology research.

scientific article

Strengths and limitations of healthcare databases in the evaluation of hypoglycaemia

scientific article published on 27 April 2017

Systematic review on the prevalence, frequency and comparative value of adverse events data in social media.

scientific article

Systemic safety of bevacizumab versus ranibizumab for neovascular age-related macular degeneration

scientific article

Systemic safety of bevacizumab versus ranibizumab for neovascular age-related macular degeneration

scientific article (published 2014-07-24)

The International Community-Acquired Pneumonia (CAP) Collaboration Cohort (ICCC) study: rationale, design and description of study cohorts and patients.

scientific article

The Prognostic Value of Anticholinergic Burden Measures in Relation to Mortality in Older Individuals: A Systematic Review and Meta-Analysis

scientific article published on 29 April 2020

The contribution of different information sources for adverse effects data

scientific article

The effect of co-trimoxazole on serum potassium concentration: safety evaluation of a randomized controlled trial.

scientific article published on 13 February 2017

The effects of hypoglycaemia and dementia on cardiovascular events, falls and fractures and all-cause mortality in older individuals: A retrospective cohort study

scientific article published on 12 June 2019

The feasibility of a search filter for the adverse effects of nondrug interventions in MEDLINE and Embase

scientific article published on 27 September 2017

The performance of adverse effects search filters in MEDLINE and EMBASE.

scientific article published on 14 March 2012

The safety of rosiglitazone in the treatment of Type 2 diabetes

article published in 2008

Thiazolidinediones and associated risk of bladder cancer: a systematic review and meta-analysis

scientific article

Tiotropium in chronic obstructive pulmonary disease

scientific article

Treatment as Required versus Regular Monthly Treatment in the Management of Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

scientific article

Two of the authors respond:.

scientific article published in April 2009

Unpublished data can be of value in systematic reviews of adverse effects: methodological overview

scientific article

Uptake of methods to deal with publication bias in systematic reviews has increased over time, but there is still much scope for improvement

scientific article

Use of antiplatelet drugs in stroke prevention: time for a rethink?

scientific article

Use of indirect comparison methods in systematic reviews: a survey of Cochrane review authors.

scientific article published on 19 December 2011

Value of severity scales in predicting mortality from community-acquired pneumonia: systematic review and meta-analysis.

scientific article

Vegetarian diet, Seventh Day Adventists and risk of cardiovascular mortality: a systematic review and meta-analysis.

scientific article

Vegetarian diets and Adventists

scientific article

Volatile organic compounds associated with diagnosis and disease characteristics in asthma - A systematic review

scientific article published on 16 May 2020

Why are medical and health-related studies not being published? A systematic review of reasons given by investigators

scientific article

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