List of works - Tamas Balla

A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

scientific article published in Journal of Biological Chemistry

A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes.

scientific article published on 07 August 2009

A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

scientific article published in Journal of Biological Chemistry

A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha

scientific article published on 09 January 2019

A membrane capture assay for lipid kinase activity

scientific article

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

scientific article

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

scientific article

A study on the interaction of ACTH and prostaglandin F2α ⬇️

scientific article published on March 1, 1977

A tail of new lipids.

scientific article

Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

scientific article

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains.

scientific article

Angiotensin II and FCCP mobilizes calcium from different intracellular pools in adrenal glomerulosa cells; analysis of calcium fluxes.

scientific article published in August 1985

Angiotensin II receptors and mechanisms of action in adrenal glomerulosa cells.

scientific article published on January 1987

Angiotensin II stimulates phosphatidylinositol turnover in adrenal glomerulosa cells by a calcium-independent mechanism

scientific article published on 01 August 1983

Angiotensin-induced formation and metabolism of inositol polyphosphates in bovine adrenal glomerulosa cells

scientific article published on 01 January 1987

Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix

scientific article published on 5 November 2015

Ca2+ and lipid signals hold hands at endoplasmic reticulum-plasma membrane contact sites

scientific article published on 6 December 2017

Cell biology: Lipid code for membrane recycling

scientific article published on 13 January 2016

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

scientific article

Characterization of Recombinant Phosphatidylinositol 4-Kinase β Reveals Auto- and Heterophosphorylation of the Enzyme

scientific article published in Journal of Biological Chemistry

Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases

scientific article published in March 1996

Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication

scientific article published on 12 December 2019

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

scientific article published on 17 December 2006

Control of phosphatidylinositol turnover in adrenal glomerulosa cells

scientific article published on 01 November 1982

Critical Role of a Conserved Intramembrane Tyrosine Residue in Angiotensin II Receptor Activation

scientific article published in Journal of Biological Chemistry

Demonstration of Angiotensin II-induced Ras Activation in the trans-Golgi Network and Endoplasmic Reticulum Using Bioluminescence Resonance Energy Transfer-based Biosensors ⬇️

scientific article published on November 8, 2010

Dependence of agonist activation on a conserved apolar residue in the third intracellular loop of the AT1 angiotensin receptor.

scientific article published on September 1996

Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modeling

scientific article

Distinct properties of the two isoforms of CDP-diacylglycerol synthase

scientific article

Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis

scientific article

EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors

scientific article

Effects of lithium on angiotensin-stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship

article

Endosomal sorting of VAMP3 is regulated by PI4K2A.

scientific article

Finding Partners for PI3K : When 84 Is Better Than 101

scientific article published on 09 June 2009

Formation of inositol 1,3,4,6-tetrakisphosphate during angiotensin II action in bovine adrenal glomerulosa cells.

scientific article published in October 1987

Found in the crystal: phospholipid ligands for nuclear orphan receptors

scientific article published on 01 September 2005

Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIα

scientific article published on 13 May 2011

Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis

scientific article published on 8 April 2015

Green light to illuminate signal transduction events.

scientific article published on 08 October 2009

High-performance reversed-phase ion-pair chromatographic study of myo-inositol phosphates

scientific article published on 01 December 1990

How accurately can we image inositol lipids in living cells?

scientific article published in July 2000

Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.

scientific article

Inositol lipid regulation of lipid transfer in specialized membrane domains.

scientific article published on 13 March 2013

Inositol polyphosphate production and regulation of cytosolic calcium during the biphasic activation of adrenal glomerulosa cells by angiotensin II

scientific article published on 01 April 1989

Inositol-lipid binding motifs: signal integrators through protein-lipid and protein-protein interactions

scientific article

Intracellular curvature-generating proteins in cell-to-cell fusion.

scientific article published on December 2011

Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate.

scientific article published in July 2000

Isolation and molecular cloning of wortmannin-sensitive bovine type III phosphatidylinositol 4-kinases.

scientific article published on July 1997

Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions

scientific article published on 4 April 2016

Live cell imaging of phosphoinositides with expressed inositide binding protein domains

scientific article published on 16 October 2008

Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study

scientific article

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

scientific article

Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha

scientific article

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

scientific article published on May 2015

Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?

scientific article

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

scientific article published in Journal of Biological Chemistry

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

scientific article

ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at plasma membrane-ER contact sites

scientific article published on 16 March 2020

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

scientific article

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.

scientific article

Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.

scientific article published on 10 January 2014

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

scientific article (publication date: 16 April 1999)

Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic.

scientific article

Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion

scientific article published on 13 March 2019

Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

scientific article published in Journal of Biological Chemistry

Phosphatidylinositol 4-kinases

scientific journal article

Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis

scientific article

Phosphatidylinositol and phosphatidic acid transport between the ER and plasma membrane during PLC activation requires the Nir2 protein.

scientific article published on February 2016

Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence.

scientific article published on 28 May 2015

Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation.

scientific article

Phosphoinositide signaling: new tools and insights.

scientific article

Phosphoinositide-derived messengers in endocrine signaling.

scientific article

Phosphoinositides: tiny lipids with giant impact on cell regulation

scientific article

Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.

scientific article

Polyphosphoinositide binding domains: Key to inositol lipid biology.

scientific article

Possible role of calcium uptake and calmodulin in adrenal glomerulosa cells: effects of verapamil and trifluoperazine.

scientific article published on April 1982

Putting G protein-coupled receptor-mediated activation of phospholipase C in the limelight

scientific article

Quantifying lipid changes in various membrane compartments using lipid binding protein domains

scientific article published on 31 December 2016

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

scientific article

Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export

scientific article

Regulation of Angiotensin II-stimulated Ca2+Oscillations by Ca2+Influx Mechanisms in Adrenal Glomerulosa Cells

scientific article published in Journal of Biological Chemistry

Regulation of Ca2+ entry by inositol lipids in mammalian cells by multiple mechanisms

scientific article published on 22 April 2009

Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis

scientific journal article

Role of calcium ions and calmodulin in the aldosterone stimulating action of prostaglandin E2

scientific article published on 01 March 1982

STIM and Orai: the long-awaited constituents of store-operated calcium entry

scientific article

Secretion of VEGF-165 has unique characteristics, including shedding from the plasma membrane

scientific article published on 05 February 2014

Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

scientific article published on October 2005

Store-operated Ca2+ influx and subplasmalemmal mitochondria.

scientific article published on 07 May 2009

Structural and functional features and significance of the physical linkage between ER and mitochondria.

scientific article

Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

scientific article

The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells

scientific article

The crystal structure of the phosphatidylinositol 4-kinase IIα

scientific article

The effect of angiotensin II on arachidonate metabolism in adrenal glomerulosa cells

scientific article published on 01 October 1985

The effect of endogenous angiotensin on the biosynthesis of aldosterone in the rat

scientific article published on 01 November 1981

The effect of various calmodulin inhibitors of the response of adrenal glomerulosa cells to angiotensin II and cyclic AMP

article

The ligand binding site of the angiotensin AT1 receptor.

scientific article

Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.

scientific article

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

scientific article

Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex

scientific article published in Journal of Biological Chemistry

Visualization and manipulation of phosphoinositide dynamics in live cells using engineered protein domains.

scientific article published on May 2007

Visualization of cellular phosphoinositide pools with GFP-fused protein-domains

scientific article

βIII spectrin regulates the structural integrity and the secretory protein transport of the Golgi complex

scientific article published on 11 December 2012

List of works by Tamas Balla

A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes.

A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha

A membrane capture assay for lipid kinase activity

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

A study on the interaction of ACTH and prostaglandin F2α ⬇️

A tail of new lipids.

Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains.

Angiotensin II and FCCP mobilizes calcium from different intracellular pools in adrenal glomerulosa cells; analysis of calcium fluxes.

Angiotensin II receptors and mechanisms of action in adrenal glomerulosa cells.

Angiotensin II stimulates phosphatidylinositol turnover in adrenal glomerulosa cells by a calcium-independent mechanism

Angiotensin-induced formation and metabolism of inositol polyphosphates in bovine adrenal glomerulosa cells

Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix

Ca2+ and lipid signals hold hands at endoplasmic reticulum-plasma membrane contact sites

Cell biology: Lipid code for membrane recycling

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

Characterization of Recombinant Phosphatidylinositol 4-Kinase β Reveals Auto- and Heterophosphorylation of the Enzyme

Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases

Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

Control of phosphatidylinositol turnover in adrenal glomerulosa cells

Critical Role of a Conserved Intramembrane Tyrosine Residue in Angiotensin II Receptor Activation

Demonstration of Angiotensin II-induced Ras Activation in the trans-Golgi Network and Endoplasmic Reticulum Using Bioluminescence Resonance Energy Transfer-based Biosensors ⬇️

Dependence of agonist activation on a conserved apolar residue in the third intracellular loop of the AT1 angiotensin receptor.

Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modeling

Distinct properties of the two isoforms of CDP-diacylglycerol synthase

Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis

EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors

Effects of lithium on angiotensin-stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship

Endosomal sorting of VAMP3 is regulated by PI4K2A.

Finding Partners for PI3K : When 84 Is Better Than 101

Formation of inositol 1,3,4,6-tetrakisphosphate during angiotensin II action in bovine adrenal glomerulosa cells.

Found in the crystal: phospholipid ligands for nuclear orphan receptors

Genetic and functional studies of phosphatidyl-inositol 4-kinase type IIIα

Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis

Green light to illuminate signal transduction events.

High-performance reversed-phase ion-pair chromatographic study of myo-inositol phosphates

How accurately can we image inositol lipids in living cells?

Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.

Inositol lipid regulation of lipid transfer in specialized membrane domains.

Inositol polyphosphate production and regulation of cytosolic calcium during the biphasic activation of adrenal glomerulosa cells by angiotensin II

Inositol-lipid binding motifs: signal integrators through protein-lipid and protein-protein interactions

Intracellular curvature-generating proteins in cell-to-cell fusion.

Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate.

Isolation and molecular cloning of wortmannin-sensitive bovine type III phosphatidylinositol 4-kinases.

Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions

Live cell imaging of phosphoinositides with expressed inositide binding protein domains

Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha

Measurement of inositol 1,4,5-trisphosphate in living cells using an improved set of resonance energy transfer-based biosensors

Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at plasma membrane-ER contact sites

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.

Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

Phosphatidylinositol 4,5-bisphosphate and Arf6-regulated membrane traffic.

Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion

Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

Phosphatidylinositol 4-kinases

Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis

Phosphatidylinositol and phosphatidic acid transport between the ER and plasma membrane during PLC activation requires the Nir2 protein.

Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence.

Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation.

Phosphoinositide signaling: new tools and insights.

Phosphoinositide-derived messengers in endocrine signaling.

Phosphoinositides: tiny lipids with giant impact on cell regulation

Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.

Polyphosphoinositide binding domains: Key to inositol lipid biology.

Possible role of calcium uptake and calmodulin in adrenal glomerulosa cells: effects of verapamil and trifluoperazine.

Putting G protein-coupled receptor-mediated activation of phospholipase C in the limelight

Quantifying lipid changes in various membrane compartments using lipid binding protein domains

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment