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List of works by Boris Striepen

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

scientific article

A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity

scientific article published on 20 June 2019

A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus

scientific article

A Plastid Protein That Evolved from Ubiquitin and Is Required for Apicoplast Protein Import in Toxoplasma gondii.

scientific article

A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis

scientific article

A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii

scientific article

A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition

scientific article published on 18 May 2022

A novel bipartite centrosome coordinates the apicomplexan cell cycle

scientific article published on 3 March 2015

A novel dynamin-related protein has been recruited for apicoplast fission in Toxoplasma gondii

scientific article

A nucleolar AAA-NTPase is required for parasite division

scientific article published on 11 September 2013

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

scientific article

A screening pipeline for antiparasitic agents targeting cryptosporidium inosine monophosphate dehydrogenase

scientific article

A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor

scientific article (publication date: December 2011)

Adenosine kinase from Cryptosporidium parvum.

scientific article

An Alveolata secretory machinery adapted to parasite host cell invasion.

scientific article published on 25 January 2021

An apicoplast localized ubiquitylation system is required for the import of nuclear-encoded plastid proteins

scientific article (publication date: 2013)

Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development.

scientific article published in July 2003

Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.

scientific article

Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii

scientific article published on 16 December 2011

Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii

scholarly article

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.

scientific article

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance inToxoplasma gondii

scholarly article by Sethu C. Nair et al published 30 April 2012 in Journal of Experimental Medicine

Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites

scientific article (publication date: December 2011)

Autophagy-Related Protein ATG8 Has a Noncanonical Function for Apicoplast Inheritance in Toxoplasma gondii

scientific article

Beg, Borrow and Steal: Three Aspects of Horizontal Gene Transfer in the Protozoan Parasite, Cryptosporidium parvum

scientific article

Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase

scientific article published on 01 September 2020

Building the perfect parasite: cell division in apicomplexa

scientific article published in June 2007

Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.

scientific article

CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes

scientific article

Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella

scientific article

Cell division in apicomplexan parasites

scientific article published on 02 January 2014

Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii

scientific article published on February 2005

Conditional mutagenesis of a novel choline kinase demonstrates plasticity of phosphatidylcholine biogenesis and gene expression in Toxoplasma gondii

scientific article

Constitutive Calcium-independent Release of Toxoplasma gondii Dense Granules Occurs through the NSF/SNAP/SNARE/Rab Machinery

scientific article published in Journal of Biological Chemistry

Criticism: what to do about science's bad public image?

scientific article published in Nature

Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural, and dynamic properties that can be exploited for drug design

scientific article published on 21 July 2004

Cryptosporidium.

scientific article published in March 2018

Daughter cell assembly in the protozoan parasite Toxoplasma gondii

scientific article

Defining the cell cycle for the tachyzoite stage of Toxoplasma gondii.

scientific article published in July 2001

Deploying parasite profilin on a mission of invasion and danger

scientific article published on February 2008

Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii

scientific article published in May 2009

Dynamics of Neutrophil Migration in Lymph Nodes during Infection

scholarly article by Tatyana Chtanova et al published October 2008 in Immunity

Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node

scientific article

Dynamics of neutrophil migration in lymph nodes during infection

scientific article

Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7.

scientific article

Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase

scientific article published on 30 January 2013

Expression, selection, and organellar targeting of the green fluorescent protein in Toxoplasma gondii.

scientific article published in May 1998

Fluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa

scientific article

Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii

scientific article

Gene transfer in the evolution of parasite nucleotide biosynthesis

scholarly article

Generating and Maintaining Transgenic Cryptosporidium parvum Parasites

scientific article published on 11 August 2017

Genetic Manipulation of Toxoplasma gondii

Genetic Manipulation of Toxoplasma gondii

Genetic complementation in apicomplexan parasites

scientific article

Genetic evidence that an endosymbiont-derived endoplasmic reticulum-associated protein degradation (ERAD) system functions in import of apicoplast proteins

scientific article published on 06 October 2009

Genetic manipulation of the Toxoplasma gondii genome by fosmid recombineering.

scientific article

Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum.

scientific article

Genetic rescue of a Toxoplasma gondii conditional cell cycle mutant

scientific article

Genomics meets transgenics in search of the elusive Cryptosporidium drug target

scientific article published in August 2004

Glucosylation of Glycosylphosphatidylinositol Membrane Anchors: Identification of Uridine Diphosphate−Glucose as the Direct Donor for Side Chain Modification inToxoplasma gondiiUsing Carbohydrate Analogues†

scientific article published on 01 February 1999

Glycosyl-phosphatidylinositols of Trypanosoma congolense: Two Common Precursors but a New Protein-anchor

scientific article published on 01 August 1996

High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein

scientific article

IMP dehydrogenase from the protozoan parasite Toxoplasma gondii

scientific article

Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

scientific article published on 30 August 2014

Identification of a sporozoite-specific member of the Toxoplasma SAG superfamily via genetic complementation

scientific article published in April 2004

In Vitro and In Vivo Activities of Sulfur-Containing Linear Bisphosphonates against Apicomplexan Parasites

scientific article

Interleukin-10 does not contribute to the pathogenesis of a virulent strain of Toxoplasma gondii

scientific article published on 01 June 2001

Intraepithelial gammadelta+ lymphocytes maintain the integrity of intestinal epithelial tight junctions in response to infection.

scientific article published in September 2006

Isolation and Characterization of TgVP1, a Type I Vacuolar H+-translocating Pyrophosphatase fromToxoplasma gondii

scientific article published in Journal of Biological Chemistry

Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum

scientific article published on 02 September 2019

Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii

scientific article

Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans

scientific article published on July 2013

Live imaging of the Cryptosporidium parvum life cycle reveals direct development of male and female gametes from type I meronts

scientific article published on 18 April 2022

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

scientific article published on 20 March 2019

Make it or take it: fatty acid metabolism of apicomplexan parasites

scientific article

Malaria: The gatekeeper revealed

scientific article published in June 2009

Mining the Plasmodium genome database to define organellar function: what does the apicoplast do? ⬇️

scientific article

Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii.

scientific article

Molecular genetic transfection of the coccidian parasite Sarcocystis neurona

scientific article published on 30 June 2006

Molecular structure of the "low molecular weight antigen" of Toxoplasma gondii: a glucose alpha 1-4 N-acetylgalactosamine makes free glycosyl-phosphatidylinositols highly immunogenic.

scientific article published in March 1997

More membranes, more proteins: complex protein import mechanisms into secondary plastids ⬇️

scientific article published on October 30, 2010

Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread

scientific article

Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection

scientific article published on 24 May 2017

Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

scientific article (publication date: 13 October 1998)

Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase

scientific article

PfClpC Is an Essential Clp Chaperone Required for Plastid Integrity and Clp Protease Stability in Plasmodium falciparum.

scientific article published in November 2017

Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum.

scientific article published on 27 December 2012

Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neurona

scientific article published in August 2005

Prodrug activation by Cryptosporidium thymidine kinase

scientific article

Protein sorting in complex plastids

scientific article

Sarcocystis neurona merozoites express a family of immunogenic surface antigens that are orthologues of the Toxoplasma gondii surface antigens (SAGs) and SAG-related sequences

scientific article

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase

scientific article published on 5 September 2012

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

scientific article published on 24 January 2012

Studying the cell biology of apicomplexan parasites using fluorescent proteins

scientific article

Switching parasite proteins on and off.

scientific article published in December 2007

Tagging genes and trapping promoters in Toxoplasma gondii by insertional mutagenesis

scientific article

Targeting Prokaryotic Enzymes in the Eukaryotic Pathogen Cryptosporidium

Targeting a Prokaryotic Protein in a Eukaryotic Pathogen: Identification of Lead Compounds against Cryptosporidiosis

Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against cryptosporidiosis

scientific article published on January 2008

Targeting and processing of nuclear-encoded apicoplast proteins in plastid segregation mutants of Toxoplasma gondii.

scientific article published on 23 April 2001

Targeting of soluble proteins to the rhoptries and micronemes in Toxoplasma gondii

scientific article published on 01 March 2001

Teaching old drugs new tricks to stop malaria invasion in its tracks

scientific article published on 8 September 2015

The Algal Past and Parasite Present of the Apicoplast ⬇️

scientific article published on June 26, 2013

The Import of Proteins into the Mitochondrion of Toxoplasma gondii

scientific article (publication date: 9 September 2016)

The apicoplast: a red alga in human parasites ⬇️

scientific article published on January 1, 2011

The cat is out of the bag: How parasites know their hosts

scientific article published on 05 September 2019

The cell biology of secondary endosymbiosis--how parasites build, divide and segregate the apicoplast

scientific article published on September 2006

The dense granule antigen, GRA2 of Toxoplasma gondii is a glycoprotein containing O-linked oligosaccharides

scientific article published on 01 November 1998

The intestinal parasite <i>Cryptosporidium</i> is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6

scientific article published on 01 January 2021

The intracellular parasite Toxoplasma gondii depends on the synthesis of long-chain and very long-chain unsaturated fatty acids not supplied by the host cell

scientific article

The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista.

The plastid of Toxoplasma gondii is divided by association with the centrosomes

scientific article

The toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival

scientific article

Tic22 Is an Essential Chaperone Required for Protein Import into the Apicoplast

scientific article

Toxoplasma gondii Tic20 is essential for apicoplast protein import

scholarly article

Toxoplasma gondii Toc75 Functions in Import of Stromal but not Peripheral Apicoplast Proteins

scientific article (publication date: December 2015)

Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin

scientific article

Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle

scientific article

Two Essential Light Chains Regulate the MyoA Lever Arm To Promote Toxoplasma Gliding Motility

scientific article

Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondii ⬇️

scientific article published on 22 February 2018

Two glycoforms are present in the GPI-membrane anchor of the surface antigen 1 (P30) of Toxoplasma gondii.

scientific article published in September 2001

Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis

scientific article published on 23 December 2013

What do human parasites do with a chloroplast anyway?

scientific article

cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii

scientific article published in October 2003

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