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List of works by Ralph Burkhardt

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

scientific article published on 01 September 2018

ABSTRACTS

scholarly article

Adipocytes induce distinct gene expression profiles in mammary tumor cells and enhance inflammatory signaling in invasive breast cancer cells.

scientific article

Association between echocardiographic parameters and biomarkers in probands with atrial fibrillation and different PR interval lengths: Insight from the epidemiologic LIFE Adult Study

scientific article published on 28 February 2019

Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin

scientific article published on 2 September 2017

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Association of the apolipoprotein E genotype with memory performance and executive functioning in cognitively intact elderly

scientific article

Atherosclerosis, myocardial infarction and primary hemostasis: Impact of platelets, von Willebrand factor and soluble glycoprotein VI

scientific article published on 25 June 2019

Bacterial contamination rates in extracorporeal photopheresis

scientific article published on 21 April 2020

Biomarkers for Non-Invasive Stratification of Coronary Artery Disease and Prognostic Impact on Long-Term Survival in Patients with Stable Coronary Heart Disease

scientific article published in 2022

Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles

scientific article

Cholesterol metabolism and breast cancer

scientific article published on 01 April 2016

Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13

scientific article

Control of hepatic gluconeogenesis by Argonaute2

scientific article published on 09 October 2018

Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice

scientific article published on 20 January 2011

Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction.

scientific article published on 10 July 2018

DNA methylation patterns reflect individual's lifestyle independent of obesity

scientific article published on 01 June 2022

Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells.

scientific article published on 10 May 2017

Differentiation of atrial fibrillation progression phenotypes using Troponin T

scientific article published on 07 September 2019

Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.

scientific article published on 27 May 2015

EGF (Epidermal Growth Factor) Receptor Ligands in Atrial Fibrillation: From Genomic Evidence to the Identification of New Players

scientific article published on 01 April 2019

Early Lactate Dynamics in Critically Ill Non-Traumatic Patients in a Resuscitation Room of a German Emergency Department (OBSERvE-Lactate-Study)

scientific article published on 08 December 2018

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice

scientific article

Elevating Endogenous Sphingosine-1-Phosphate (S1P) Levels Improves Endothelial Function and Ameliorates Atherosclerosis in Low Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice

scientific article published on 30 July 2018

Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020

scientific article published in 2021

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes

scientific article published on 01 May 2018

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic association of objective sleep phenotypes with a functional polymorphism in the neuropeptide S receptor gene

scientific article

Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae

scientific article

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery

scientific article published on 24 February 2017

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression

scientific article published on 9 December 2016

Higher Infection Risk among Health Care Workers and Lower Risk among Smokers Persistent across SARS-CoV-2 Waves—Longitudinal Results from the Population-Based TiKoCo Seroprevalence Study

Human brain arousal in the resting state: a genome-wide association study

scientific article published on 27 April 2018

Hyperlipidemia and cardiovascular disease: new insights on lipoprotein(a)

scientific article published on 01 June 2019

Hyperlipidemia and cardiovascular disease: reinforcement for 'lower is better'

scientific article published on 01 October 2015

Identification of macrophage arginase I as a new candidate gene of atherosclerosis resistance

scientific article published on 10 November 2005

Immune-Deficient Pfp/Rag2-/- Mice Featured Higher Adipose Tissue Mass and Liver Lipid Accumulation with Growing Age than Wildtype C57BL/6N Mice

scientific article published on 25 July 2019

Impact of Selection Bias on Estimation of Subsequent Event Risk

scientific article published in October 2017

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood

scientific article

Intra-individual alterations of serum markers routinely used in forensic pathology depending on increasing post-mortem interval

scientific article published in Scientific Reports

Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice

scientific article published on 29 November 2018

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin

scientific article published on 28 October 2015

Lipid metabolism: from genetic loci to functional understanding

scientific article published on 01 February 2017

Lipid metabolism: spotlight on modulators of lipoprotein lipase activity

scientific article published on 01 April 2018

Lipidomic profiling of human serum enables detection of pancreatic cancer

scientific article published on 10 January 2022

Matrix-dependent absorption of 8-methoxypsoralen in extracorporeal photopheresis

scientific article published on 08 July 2020

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2

scientific article published on 01 March 2022

MicroRNAs as Salivary Markers for Periodontal Diseases: A New Diagnostic Approach?

scientific article

Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning

scientific article

Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction

scientific article published on 01 September 2016

Pediatric reference data of serum lipids and prevalence of dyslipidemia: Results from a population-based cohort in Germany

scientific article

Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease

scientific article published on 09 November 2018

Protein bioavailability of Wolffia globosa duckweed, a novel aquatic plant - A randomized controlled trial

scientific article published on 11 December 2018

Quantification of Fecal Short Chain Fatty Acids by Liquid Chromatography Tandem Mass Spectrometry-Investigation of Pre-Analytic Stability

scientific article published on 28 March 2019

SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet

scientific article published on 16 March 2015

Scavenger receptor activity is increased in macrophages from rabbits with low atherosclerotic response: studies in normocholesterolemic high and low atherosclerotic response rabbits

scientific article published on 01 May 1999

Secondary hemophagocytic lymphohistiocytosis and severe liver injury induced by hepatic SARS-CoV-2 infection unmasking Wilson's disease: balancing immunosuppression

scientific article published on 04 January 2021

Secreted factors from adipose tissue reprogram tumor lipid metabolism and induce motility by modulating PPARα/ANGPTL4 and FAK

scientific article published on 28 August 2020

Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma

scientific article published on 05 February 2019

Single cell study of adipose tissue mediated lipid droplet formation and biochemical alterations in breast cancer cells

scientific article published on 01 September 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

THOC5: a novel gene involved in HDL-cholesterol metabolism

scientific article published on 10 September 2013

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice

scientific article

The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany

scientific article

Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County—Results from a Population-Based Longitudinal Study in Germany

scientific article published in 2022

Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep.

scientific article published on 5 May 2016

Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice

scientific article

Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages

scientific article published on 13 June 2018

[Molecular monitoring: an essential component of the treatment for chronic myeloid leukemia]

scientific article published on 01 October 2006

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