List of works - Ildiko Van Rhijn

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

scientific article published in Nature Communications

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

scientific article published on 06 November 2019

A conserved human T cell population targets mycobacterial antigens presented by CD1b

scientific article

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

scientific article

Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models

scientific article published on 22 April 2008

CD1 and mycobacterial lipids activate human T cells

scientific article

CD1a, CD1b, and CD1c in immunity against mycobacteria

scientific article published on January 2013

CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire

scientific article

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

scientific article published on 22 December 2013

CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis

scientific article published on 29 January 2018

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells

scientific article published on 20 March 2019

CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans

scientific article

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice

scientific article published on 2 May 2017

CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails

scientific article

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

scientific article published on 25 May 2009

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

CD1d-restricted T cell activation by nonlipidic small molecules

scholarly article

CampylobacterDNA Is Present in Circulating Myelomonocytic Cells of Healthy Persons and in Persons with Guillain‐Barré Syndrome

scientific article published on 03 January 2002

Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

scientific article

Correction: Expression Patterns of Bovine CD1 In Vivo and Assessment of the Specificities of the Anti-Bovine CD1 Antibodies

scientific article published on 5 June 2015

Crystal Structure of Bovine CD1b3 with Endogenously Bound Ligands

scientific article

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

scientific article published in 2012

Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo.

scientific article published on 02 October 2013

Discovery of invariant T cells by next-generation sequencing of the human TCR α-chain repertoire

scientific article

Discovery of trehalose phospholipids reveals functional convergence with mycobacteria

scientific article published on 25 February 2019

Donor Unrestricted T Cells: A Shared Human T Cell Response

scientific article

Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni

scientific article published on 01 March 2003

Expression patterns of bovine CD1 in vivo and assessment of the specificities of the anti-bovine CD1 antibodies

scientific article published on 27 March 2015

Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants

scientific article (publication date: April 2009)

Highly diverse TCR δ chain repertoire in bovine tissues due to the use of up to four D segments per δ chain

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products

scientific article published on 03 January 2020

Human autoreactive T cells recognize CD1b and phospholipids

scientific article

Human γδ T cells recognize CD1b by two distinct mechanisms

scientific article published on 31 August 2020

Immune response of cattle immunized with a conjugate of the glycolipid glucose monomycolate and protein

article

Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences

scientific article published on 12 October 2009

Lipid and small-molecule display by CD1 and MR1.

scientific article published on 21 September 2015

Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis

scientific article published on 28 November 2012

Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection

scientific article

Mammalian CD1 and MR1 genes

scientific article

Massive, sustained gammadelta T cell migration from the bovine skin in vivo

scientific article published on 18 January 2007

Molecular recognition of microbial lipid-based antigens by T cells.

scientific article published on 16 January 2018

Role of lipid trimming and CD1 groove size in cellular antigen presentation

scientific article published on 22 June 2006

Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo

scientific article published on 18 October 2008

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

scientific article published on 12 March 2018

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

scientific article published on 27 October 2016

T-cell activation by lipopeptide antigens

scientific article

TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire

scientific article

Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation

scientific article

The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d

scientific article

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

scientific article published on 11 September 2012

The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2.

scientific article published on 2 July 2009

The evolved functions of CD1 during infection

scientific article published on 21 June 2009

The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins

scientific article

The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle

scientific article published on 16 June 2009

Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

scientific article published on 7 December 2016

Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

scientific article published on 18 February 2020

Two canine CD1a proteins are differentially expressed in skin

scientific article published on 17 May 2008

γδ T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent.

scientific article published on 12 December 2011

List of works by Ildiko Van Rhijn

A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

A conserved human T cell population targets mycobacterial antigens presented by CD1b

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids

Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models

CD1 and mycobacterial lipids activate human T cells

CD1a, CD1b, and CD1c in immunity against mycobacteria

CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire

CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens

CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells

CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice

CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids

CD1d-restricted T cell activation by nonlipidic small molecules

CampylobacterDNA Is Present in Circulating Myelomonocytic Cells of Healthy Persons and in Persons with Guillain‐Barré Syndrome

Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

Correction: Expression Patterns of Bovine CD1 In Vivo and Assessment of the Specificities of the Anti-Bovine CD1 Antibodies

Crystal Structure of Bovine CD1b3 with Endogenously Bound Ligands

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo.

Discovery of invariant T cells by next-generation sequencing of the human TCR α-chain repertoire

Discovery of trehalose phospholipids reveals functional convergence with mycobacteria

Donor Unrestricted T Cells: A Shared Human T Cell Response

Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni

Expression patterns of bovine CD1 in vivo and assessment of the specificities of the anti-bovine CD1 antibodies

Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants

Highly diverse TCR δ chain repertoire in bovine tissues due to the use of up to four D segments per δ chain

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products

Human autoreactive T cells recognize CD1b and phospholipids

Human γδ T cells recognize CD1b by two distinct mechanisms

Immune response of cattle immunized with a conjugate of the glycolipid glucose monomycolate and protein

Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences

Lipid and small-molecule display by CD1 and MR1.

Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis

Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection

Mammalian CD1 and MR1 genes

Massive, sustained gammadelta T cell migration from the bovine skin in vivo

Molecular recognition of microbial lipid-based antigens by T cells.

Role of lipid trimming and CD1 groove size in cellular antigen presentation

Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

T-cell activation by lipopeptide antigens

TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire

Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation

The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2.

The evolved functions of CD1 during infection

The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins

The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle

Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition.

Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

Two canine CD1a proteins are differentially expressed in skin

γδ T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent.