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List of works by Giuseppe Grasso

A neglected modulator of insulin-degrading enzyme activity and conformation: The pH

scientific article published on 27 May 2015

A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au (111)

scientific article published on 23 March 2007

A ratiometric naphthalimide sensor for live cell imaging of copper(I).

scientific article published on June 2013

AP/MALDI-MS complete characterization of the proteolytic fragments produced by the interaction of insulin degrading enzyme with bovine insulin

scientific article

Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au (111) surfaces monitored by ESI-MS.

scientific article published in December 2005

Atmospheric pressure MALDI for the noninvasive characterization of carbonaceous ink from Renaissance documents

scientific article published on 21 April 2017

Carnosine protects pancreatic beta cells and islets against oxidative stress damage

scientific article published on 26 February 2018

Commentary on Ivancic et al.: Enzyme Kinetics from Circular Dichroism of Insulin Reveals Mechanistic Insights into the Regulation of Insulin-degrading Enzyme

scholarly article by Giuseppe Grasso published in November 2018

Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.

scientific article published on 27 January 2011

Copper, differently from zinc, affects the conformation, oligomerization state and activity of bradykinin.

scientific article published on 21 June 2016

Covalent modifications of the amyloid beta peptide by hydroxynonenal: Effects on metal ion binding by monomers and insights into the fibril topology

scientific article published on 20 June 2017

Effects of covalent modification by 4-hydroxy-2-nonenal on the noncovalent oligomerization of ubiquitin

scientific article published on 11 November 2016

Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme

scientific article

Formation of insulin fragments by insulin-degrading enzyme: the role of zinc(II) and cystine bridges

scientific article published on 01 February 2013

IDE Degrades Nociceptin/Orphanin FQ through an Insulin Regulated Mechanism

scientific article published on 10 September 2019

In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases

scientific article published in December 2006

Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry.

scientific article published on 31 May 2017

Mass spectrometry is a multifaceted weapon to be used in the battle against Alzheimer's disease: Amyloid beta peptides and beyond

scientific article published on 15 June 2018

Metabolism of cryptic peptides derived from neuropeptide FF precursors: the involvement of insulin-degrading enzyme

scientific article

Metal complexes and metalloproteases: targeting conformational diseases

scientific article published on August 2014

Metal ions affect insulin-degrading enzyme activity.

scientific article

Metallostasis and amyloid β-degrading enzymes.

scientific article published on August 2012

Monitoring the biomolecular interactions and the activity of Zn-containing enzymes involved in conformational diseases: experimental methods for therapeutic purposes.

scientific article published on 26 September 2014

Multiple functions of insulin-degrading enzyme: a metabolic crosslight?

scientific article published on 21 June 2017

New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes.

scientific article

Plasmonics for the study of metal ion-protein interactions.

scientific article published on 29 September 2012

Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity

scientific article published on 17 December 2019

Site directed mutagenesis of insulin-degrading enzyme allows singling out the molecular basis of peptidase versus E1-like activity: the role of metal ions

scientific article published on 01 February 2019

Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity

scientific article

Surface tailoring of polyacrylate-grafted graphene oxide for controlled interactions at the biointerface

scientific article published on 21 July 2017

THE USE OF MASS SPECTROMETRY TO STUDY ZN-METALLOPROTEASE-SUBSTRATE INTERACTIONS

scientific article published on 03 January 2020

The copper(II) and zinc(II) coordination mode of HExxH and HxxEH motif in small peptides: the role of carboxylate location and hydrogen bonding network

scientific article published on 9 October 2013

The double faced role of copper in Aβ homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration

The insulin degrading enzyme activates ubiquitin and promotes the formation of K48 and K63 diubiquitin

scientific article published on 14 September 2015

The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S.

scientific article

The proteolytic activity of insulin-degrading enzyme: a mass spectrometry study

scientific article

The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme.

scientific article published on April 2014

The role of copper(II) in the aggregation of human amylin.

scientific article

The use of mass spectrometry to study amyloid-β peptides.

scientific article

Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions

scientific article

Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

scientific article published on 10 January 2019

Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging

scientific article published on 01 September 2008

Zinc(II) complexes of ubiquitin: speciation, affinity and binding features

scientific article published on 26 August 2011

Zinc(II) interactions with brain-derived neurotrophic factor N-terminal peptide fragments: inorganic features and biological perspectives

scientific article

Zn2+'s ability to alter the distribution of Cu2+ among the available binding sites of Aβ(1-16)-polyethylenglycol-ylated peptide: implications in Alzheimer's disease

scientific article published on 25 May 2011

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