List of works by Arul Chinnaiyan

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article

A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium

scientific article

A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer

scientific article published on September 2008

A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.

scientific article published on November 2002

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

scientific article published on 18 June 2018

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

scientific article

Abstract 2795: An onco-protein axis linking polycomb repressive complex 2 and polycomb repressive complex 1 through miRNAs in cancer

Abstract 4707: Discovery and characterization of PCAT-1, a novel lincRNA implicated in prostate cancer tumorigenesis

article

Abstract 953: Mechanistic rationale for inhibition of Poly(ADP-Ribose) Polymerase in ETS gene fusion positive prostate cancer

article

Active surveillance for prostate cancer: the role of the pathologist

article

Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions

scientific article

An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer

scientific article

Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression.

scientific article published on 28 May 2018

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

scientific article published on July 2009

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

article

Antibody-based detection of ERG rearrangement-positive prostate cancer

scientific article

Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.

scientific article

Autoantibody signatures in prostate cancer

scientific article

Beyond PSA: the next generation of prostate cancer biomarkers

scientific article published on March 2012

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer

scientific article published on 18 September 2006

Characterization of KRAS rearrangements in metastatic prostate cancer

scientific article published on June 2011

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer

scientific article

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

scientific article

Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

scientific article

Chimeric transcript discovery by paired-end transcriptome sequencing

scientific article published on 10 July 2009

Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer

scientific article published on 19 May 2011

Common gene rearrangements in prostate cancer

scientific article published on 22 August 2011

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer

scientific article published on 7 December 2011

Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer

article

Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

scientific article

Coordinated regulation of polycomb group complexes through microRNAs in cancer.

scientific article

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ⬇️

scientific article

Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death

scientific article

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

scientific article

Defining aggressive prostate cancer using a 12-gene model

scientific article

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

scientific article

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

scientific article published on August 2007

EML4-ALK fusion lung cancer: a rare acquired event

scientific article

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

scientific article

ETS gene fusions in prostate cancer: from discovery to daily clinical practice

scientific article published on 24 April 2009

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

scientific article

Expressed pseudogenes in the transcriptional landscape of human cancers

scientific article (publication date: 22 June 2012)

Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

scientific article published in June 2003

Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors

scientific article

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

scientific article published on July 2012

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

scientific article published on 20 November 2011

Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer

scientific article

Gene-expression profiles in hereditary breast cancer.

scientific article

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.

scientific article published on September 2012

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

scientific article

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

scientific article

HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

scientific article

Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease

scientific article

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

scientific article published on 10 April 2012

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 01 November 2018

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer

scientific article published on December 2016

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

scientific article published on 06 July 2016

Integrative Clinical Genomics of Advanced Prostate Cancer.

scientific article

Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth

scientific article published on September 2015

Integrative analysis of genomic aberrations associated with prostate cancer progression

scientific article

Integrative clinical genomics of advanced prostate cancer

scientific article

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

article

Integrative molecular concept modeling of prostate cancer progression.

scientific article

Internet-based Profiler system as integrative framework to support translational research

scientific article

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

scientific article

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

scientific article

Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination

scientific article published on 04 January 2021

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

scientific article

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

scientific article

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

scientific article

Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

scientific article published on 17 November 2004

Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

scientific article

Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma

scientific article published on 25 January 2013

Overexpression of the Long Non-coding RNA SChLAP1 Independently Predicts Lethal Prostate Cancer

scientific article published on 23 December 2015

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

scientific article published in June 2004

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

scientific article

Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures

scientific article

Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States

scientific article published on 7 July 2009

Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification

scientific article published on 26 June 2014

Publisher Correction: The long tail of oncogenic drivers in prostate cancer

scientific article published on 01 July 2019

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

scientific article

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

scientific article

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

scientific article

Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia

scientific article published on 4 February 2013

Role of the TMPRSS2-ERG gene fusion in prostate cancer

scientific article

Role of transcriptional corepressor CtBP1 in prostate cancer progression

scientific article

SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.

scientific article published in March 2017

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

scientific article published on 01 June 2007

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

scientific article published on September 2006

Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer

scientific article published on 22 December 2021

Targeting the MLL complex in castration-resistant prostate cancer

scientific article

The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, Internationa

scientific article published on 05 August 2014

The lncRNA PCAT29 inhibits oncogenic phenotypes in prostate cancer

scientific article

The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex

scientific article published on 29 September 2013

The long tail of oncogenic drivers in prostate cancer.

scientific article published on 2 April 2018

The role of SPINK1 in ETS rearrangement-negative prostate cancers

scientific article

The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells

scientific article published on 19 October 2002

The role of metastasis-associated protein 1 in prostate cancer progression

scientific article published in February 2004

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes

scientific article

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

scientific article

Transcriptome sequencing to detect gene fusions in cancer

scientific article

Transcriptomic heterogeneity in multifocal prostate cancer

scientific article

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

scientific article published on 14 April 2009

Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA.

scientific article published on August 2011

Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors

scientific article

Whole transcriptome amplification for gene expression profiling and development of molecular archives

scientific article

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