List of works - Raimundo Gargallo

Application of Eigenstructure Tracking Analysis and SIMPLISMA to the Study of the Protonation Equilibria of cCMP and Several Polynucleotides

scientific article published in July 1996

Application of a multivariate curve resolution procedure to the analysis of second-order melting data of synthetic and natural polynucleotides.

scientific article

Application of a self-modeling curve resolution approach to the study of solvent effects on the acid-base and copper (II)-complexing behavior of polyuridylic acid

scientific article published on 01 August 1996

Application of multivariate resolution methods to the study of biochemical and biophysical processes.

scientific article published on April 2004

Chemical equilibria studies using multivariate analysis methods ⬇️

scientific article published on October 28, 2010

Chemometrics: an important tool for monitoring interactions of vitamin B7 with bovine serum albumin with the aim of developing an efficient biosensing system for the analysis of protein.

scientific article published on 28 September 2014

Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra.

scientific article

Combination of electrochemistry with chemometrics to introduce an efficient analytical method for simultaneous quantification of five opium alkaloids in complex matrices.

scientific article published on 26 July 2014

Destabilization of quadruplex DNA by 8-aminoguanine.

scientific article

Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques.

scientific article published on 6 February 2018

Experimental Methods for Studying the Interactions between G-Quadruplex Structures and Ligands ⬇️

scientific article published on January 1, 2012

Hard/soft hybrid modeling of temperature-induced unfolding processes involving G-quadruplex and i-motif nucleic acid structures.

scientific article published on 24 August 2014

Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5'-(C3TA2)4-3' sequence of the human telomere

scientific article published on 12 July 2011

Molecular dynamics simulation of highly charged proteins: comparison of the particle-particle particle-mesh and reaction field methods for the calculation of electrostatic interactions

scientific article published on October 2003

Multivariate Curve Resolution Applied to the Analysis and Resolution of Two-Dimensional [1H,15N] NMR Reaction Spectra

article

Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes

scientific article published on 01 August 2018

Nucleic Acid i-Motif Structures in Analytical Chemistry

scientific article published on 3 March 2016

Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene

article

Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.

scientific article

Resolution of parallel and antiparallel oligonucleotide triple helices formation and melting processes by multivariate curve resolution

scientific article published on 01 October 2003

Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops

article

Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter

scientific article published on 06 August 2007

Specific loop modifications of the thrombin-binding aptamer trigger the formation of parallel structures

scientific article published on 02 January 2014

Spectrometric study of the folding process of i-motif-forming DNA sequences upstream of the c-kit transcription initiation site.

scientific article published on 14 October 2010

Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods.

scientific article

Stabilization of Telomeric I-Motif Structures by (2'S)-2'-Deoxy-2'-C-Methylcytidine Residues

scientific article published on 13 April 2017

Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41

scientific article published on 04 October 2019

Structural properties of g,t-parallel duplexes

scientific article

Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines

scientific article

Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling

scientific article published on 01 July 2018

Study of the Intercalation Equilibrium between the Polynucleotide Poly(adenylic)-Poly(uridylic) Acid and the Ethidium Bromide Dye by Means of Multivariate Curve Resolution and the Multivariate Extension of the Continuous Variation and Mole Ratio Met

scientific article published on 01 October 1999

Study of the influence of temperature on the dynamics of the catalytic cleft in 1,3-1,4-beta-glucanase by molecular dynamics simulations

scientific article published on 09 March 2006

Synthesis and g-quadruplex-binding properties of defined acridine oligomers.

scientific article published on 13 June 2010

Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand

article

Tetraplex DNA transitions within the human c-myc promoter detected by multivariate curve resolution of fluorescence resonance energy transfer

scientific article published on 01 December 2005

The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA.

scientific article

The RNA Stem-Loop to G-Quadruplex Equilibrium Controls Mature MicroRNA Production inside the Cell.

scientific article published on 10 November 2015

The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures

scientific article

The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer ⬇️

scientific article published on June 9, 2012

The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.

scientific article published on 9 March 2017

Three-way curve resolution applied to the study of solvent effect on the thermodynamic and conformational transitions related to the protonation of polycytidylic acid

scientific article published on 01 July 1997

Three-way multivariate curve resolution applied to speciation of acid-base and thermal unfolding transitions of an alternating polynucleotide

scientific article published on December 1, 2001

Triplex formation using oligonucleotide clamps carrying 8-aminopurines.

scientific article published on January 2007

Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery

scientific article published on 24 December 2020

Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure.

scientific article published on March 2016

Using principal component analysis to find correlations between loop-related and thermodynamic variables for G-quadruplex-forming sequences.

scientific article published on 7 May 2010

Variable-temperature size exclusion chromatography for the study of the structural changes in g-quadruplex

scientific article

i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene

scientific article published on 12 June 2017

pH-Modulated Watson-Crick duplex-quadruplex equilibria of guanine-rich and cytosine-rich DNA sequences 140 base pairs upstream of the c-kit transcription initiation site.

scientific article

List of works by Raimundo Gargallo

Application of Eigenstructure Tracking Analysis and SIMPLISMA to the Study of the Protonation Equilibria of cCMP and Several Polynucleotides

Application of a multivariate curve resolution procedure to the analysis of second-order melting data of synthetic and natural polynucleotides.

Application of a self-modeling curve resolution approach to the study of solvent effects on the acid-base and copper (II)-complexing behavior of polyuridylic acid

Application of multivariate resolution methods to the study of biochemical and biophysical processes.

Chemical equilibria studies using multivariate analysis methods ⬇️

Chemometrics: an important tool for monitoring interactions of vitamin B7 with bovine serum albumin with the aim of developing an efficient biosensing system for the analysis of protein.

Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra.

Combination of electrochemistry with chemometrics to introduce an efficient analytical method for simultaneous quantification of five opium alkaloids in complex matrices.

Destabilization of quadruplex DNA by 8-aminoguanine.

Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques.

Experimental Methods for Studying the Interactions between G-Quadruplex Structures and Ligands ⬇️

Hard/soft hybrid modeling of temperature-induced unfolding processes involving G-quadruplex and i-motif nucleic acid structures.

Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif formed by the 5'-(C3TA2)4-3' sequence of the human telomere

Molecular dynamics simulation of highly charged proteins: comparison of the particle-particle particle-mesh and reaction field methods for the calculation of electrostatic interactions

Multivariate Curve Resolution Applied to the Analysis and Resolution of Two-Dimensional [1H,15N] NMR Reaction Spectra

Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes

Nucleic Acid i-Motif Structures in Analytical Chemistry

Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene

Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.

Resolution of parallel and antiparallel oligonucleotide triple helices formation and melting processes by multivariate curve resolution

Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops

Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1 promoter

Specific loop modifications of the thrombin-binding aptamer trigger the formation of parallel structures

Spectrometric study of the folding process of i-motif-forming DNA sequences upstream of the c-kit transcription initiation site.

Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the central base sequences -XGCY- and -XGGCCY- using multivariate methods.

Stabilization of Telomeric I-Motif Structures by (2'S)-2'-Deoxy-2'-C-Methylcytidine Residues

Stabilization of c-KIT G-Quadruplex DNA Structures by the RNA Polymerase I Inhibitors BMH-21 and BA-41

Structural properties of g,t-parallel duplexes

Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines

Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling

Study of the Intercalation Equilibrium between the Polynucleotide Poly(adenylic)-Poly(uridylic) Acid and the Ethidium Bromide Dye by Means of Multivariate Curve Resolution and the Multivariate Extension of the Continuous Variation and Mole Ratio Met

Study of the influence of temperature on the dynamics of the catalytic cleft in 1,3-1,4-beta-glucanase by molecular dynamics simulations

Synthesis and g-quadruplex-binding properties of defined acridine oligomers.

Targeting the G-quadruplex-forming region near the P1 promoter in the human BCL-2 gene with the cationic porphyrin TMPyP4 and with the complementary C-rich strand

Tetraplex DNA transitions within the human c-myc promoter detected by multivariate curve resolution of fluorescence resonance energy transfer

The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA.

The RNA Stem-Loop to G-Quadruplex Equilibrium Controls Mature MicroRNA Production inside the Cell.

The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures

The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer ⬇️

The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.

Three-way curve resolution applied to the study of solvent effect on the thermodynamic and conformational transitions related to the protonation of polycytidylic acid

Three-way multivariate curve resolution applied to speciation of acid-base and thermal unfolding transitions of an alternating polynucleotide

Triplex formation using oligonucleotide clamps carrying 8-aminopurines.

Tuning G-Quadruplex Nanostructures with Lipids. Towards Designing Hybrid Scaffolds for Oligonucleotide Delivery

Understanding the effect of the nature of the nucleobase in the loops on the stability of the i-motif structure.

Using principal component analysis to find correlations between loop-related and thermodynamic variables for G-quadruplex-forming sequences.

Variable-temperature size exclusion chromatography for the study of the structural changes in g-quadruplex

i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene

pH-Modulated Watson-Crick duplex-quadruplex equilibria of guanine-rich and cytosine-rich DNA sequences 140 base pairs upstream of the c-kit transcription initiation site.