List of works - Tobias Jung

"Cyt/Nuc", a customizable and documenting ImageJ macro for evaluation of protein distributions between cytosol and nucleus

scientific article published on 10 January 2018

4-Hydroxynonenal (HNE) modified proteins in metabolic diseases

scientific article published in November 2016

Accumulation of modified proteins and aggregate formation in aging.

scientific article

Actual Isothermal Effects of Water-Filtered Infrared A-Irradiation

scientific article published on 12 March 2015

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

scientific article

Age-related differences in oxidative protein-damage in young and senescent fibroblasts

scientific article published on 25 December 2008

Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity

scientific article published on 23 October 2010

Age-related oxidative changes in pancreatic islets are predominantly located in the vascular system.

scientific article published on 29 December 2017

An experimental setup for the measurement of nonthermal effects during water-filtered infrared A-irradiation of mammalian cell cultures.

scientific article

Carbonylation of the cytoskeletal protein actin leads to aggregate formation.

scientific article published on 15 June 2012

Cardiomyocyte Contractility and Autophagy in a Premature Senescence Model of Cardiac Aging

scientific article published on 14 April 2020

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

scientific article published in December 2004

Degradation of glycated bovine serum albumin in microglial cells.

scientific article published on 17 November 2005

Distribution of oxidized and HNE-modified proteins in U87 cells.

scientific article published on January 2005

Experimental basis for discriminating between thermal and athermal effects of water‐filtered infrared A irradiation ⬇️

scientific article published on July 1, 2012

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

scientific article published on 07 December 2016

Hyperammonemia causes protein oxidation and enhanced proteasomal activity in response to mitochondria-mediated oxidative stress in rat primary astrocytes

scientific article

Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology

scientific article published on 12 October 2015

Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease.

scientific article published in May 2009

Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress.

scientific article published on 28 December 2005

Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages.

scientific article published in April 2004

Lipofuscin inhibits the proteasome by binding to surface motifs

scientific article published on 16 December 2010

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

scientific journal article

Lipofuscin-bound iron is a major intracellular source of oxidants: role in senescent cells

scientific article published on 29 January 2010

Low proteasomal activity in fast skeletal muscle fibers is not associated with increased age-related oxidative damage

Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts.

scientific article published on 26 October 2016

Metabolism-induced oxidative stress is a mediator of glucose toxicity in HT22 neuronal cells.

scientific article

Mitochondrial contribution to lipofuscin formation.

scientific article published on 25 January 2017

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

scientific article published on 2 December 2006

Oxidative stress related changes in the brain of hypercholesterolemic rabbits.

scientific article published in January 2008

Oxidized proteins: intracellular distribution and recognition by the proteasome

scientific article published on March 2007

Pathophysiological importance of aggregated damaged proteins.

scientific article published on 12 March 2014

Protein aggregates and proteostasis in aging: Amylin and β-cell function.

scientific article published on 23 March 2018

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin

scientific article published on 22 December 2006

Protein oxidation and degradation during postmitotic senescence.

scientific article published on November 2005

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

scientific article published in Scientific Reports

Proteostasis, oxidative stress and aging

scientific article published on 12 July 2017

Reduced autophagy leads to an impaired ferritin turnover in senescent fibroblasts.

scientific article published on 24 October 2016

Reprint of "accumulation of modified proteins and aggregate formation in aging".

scientific article

SIPS as a model to study age-related changes in proteolysis and aggregate formation

scientific article published on 26 July 2017

Structure of the proteasome.

scientific article published on January 2012

Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.

scientific article

The "MYOCYTER" - Convert cellular and cardiac contractions into numbers with ImageJ

scientific article published on 22 October 2019

The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome.

scientific article published on 03 August 2016

The proteasomal system.

scientific article published on 14 April 2009

The proteasome and its role in nuclear protein maintenance.

scientific article published on 10 April 2007

The proteasome and the degradation of oxidized proteins: Part I-structure of proteasomes.

scientific article published on 19 January 2013

The proteasome and the degradation of oxidized proteins: Part II - protein oxidation and proteasomal degradation

scientific article

Tocopherol-mediated modulation of age-related changes in microglial cells: turnover of extracellular oxidized protein material

scientific article published on 9 March 2006

Vimentin is the specific target in skin glycation. Structural prerequisites, functional consequences, and role in skin aging

scientific article published on 13 June 2007

List of works by Tobias Jung

"Cyt/Nuc", a customizable and documenting ImageJ macro for evaluation of protein distributions between cytosol and nucleus

4-Hydroxynonenal (HNE) modified proteins in metabolic diseases

Accumulation of modified proteins and aggregate formation in aging.

Actual Isothermal Effects of Water-Filtered Infrared A-Irradiation

Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

Age-related differences in oxidative protein-damage in young and senescent fibroblasts

Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity

Age-related oxidative changes in pancreatic islets are predominantly located in the vascular system.

An experimental setup for the measurement of nonthermal effects during water-filtered infrared A-irradiation of mammalian cell cultures.

Carbonylation of the cytoskeletal protein actin leads to aggregate formation.

Cardiomyocyte Contractility and Autophagy in a Premature Senescence Model of Cardiac Aging

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

Degradation of glycated bovine serum albumin in microglial cells.

Distribution of oxidized and HNE-modified proteins in U87 cells.

Experimental basis for discriminating between thermal and athermal effects of water‐filtered infrared A irradiation ⬇️

Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

Hyperammonemia causes protein oxidation and enhanced proteasomal activity in response to mitochondria-mediated oxidative stress in rat primary astrocytes

Identification of an unstable 4-hydroxynoneal modification on the 20S proteasome subunit α7 by recombinant antibody technology

Impact of magnetic labeling on human and mouse stem cells and their long-term magnetic resonance tracking in a rat model of Parkinson disease.

Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress.

Iron oxide particles for molecular magnetic resonance imaging cause transient oxidative stress in rat macrophages.

Lipofuscin inhibits the proteasome by binding to surface motifs

Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts

Lipofuscin-bound iron is a major intracellular source of oxidants: role in senescent cells

Low proteasomal activity in fast skeletal muscle fibers is not associated with increased age-related oxidative damage

Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts.

Metabolism-induced oxidative stress is a mediator of glucose toxicity in HT22 neuronal cells.

Mitochondrial contribution to lipofuscin formation.

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

Oxidative stress related changes in the brain of hypercholesterolemic rabbits.

Oxidized proteins: intracellular distribution and recognition by the proteasome

Pathophysiological importance of aggregated damaged proteins.

Protein aggregates and proteostasis in aging: Amylin and β-cell function.

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin

Protein oxidation and degradation during postmitotic senescence.

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Proteostasis, oxidative stress and aging

Reduced autophagy leads to an impaired ferritin turnover in senescent fibroblasts.

Reprint of "accumulation of modified proteins and aggregate formation in aging".

SIPS as a model to study age-related changes in proteolysis and aggregate formation

Structure of the proteasome.

Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.

The "MYOCYTER" - Convert cellular and cardiac contractions into numbers with ImageJ

The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome.

The proteasomal system.

The proteasome and its role in nuclear protein maintenance.

The proteasome and the degradation of oxidized proteins: Part I-structure of proteasomes.

The proteasome and the degradation of oxidized proteins: Part II - protein oxidation and proteasomal degradation

Tocopherol-mediated modulation of age-related changes in microglial cells: turnover of extracellular oxidized protein material

Vimentin is the specific target in skin glycation. Structural prerequisites, functional consequences, and role in skin aging