List of works - Arthur M. Lesk

28-way vertebrate alignment and conservation track in the UCSC Genome Browser

scientific article (publication date: December 2007)

A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?

scientific article published in December 2002

A combinatorial study of the effects of admitting non-watson-crick base pairings and of base composition on the helix-forming potential of polynucleotides of random sequence ⬇️

scientific article published on 01 March 1974

A cross-reference table between the Protein Data Bank of macromolecular structures and the National Biomedical Research Foundation-Protein Identification Resource amino acid sequence data bank

scientific article

A method for multiple superposition of structures

scientific article published in January 1992

A tale of two proteinases

scientific article published on 01 August 1994

Alarums and diversions

scientific article published in Nature

Alignment of the amino acid sequences of distantly related proteins using variable gap penalties

scientific article published on 01 October 1986

Amyloid fibers are water-filled nanotubes

scientific article

An atlas of serpin conformations.

scientific article published on February 1998

An encoding technique to facilitate the detection of homologies in biopolymer sequences ⬇️

scientific article published on December 21, 1977

Antibody modeling: implications for engineering and design.

scientific article

Antibody structure, prediction and redesign

scientific article

Application of the common features of transfer RNAs to the determination of their nucleotide sequences ⬇️

scientific article published on November 5, 1971

Aprés moi lé deluge

scientific article published in Nature

Assessment of novel fold targets in CASP4: predictions of three-dimensional structures, secondary structures, and interresidue contacts.

scientific article

Bioinformatics of Protein Function

Brave new proteins: what evolution reveals about protein structure.

scientific article

CASP2: Report on ab initio predictions ⬇️

scientific article published on 01 January 1997

Canonical structures for the hypervariable regions of T cell alphabeta receptors

scientific article

Canonical structures for the hypervariable regions of immunoglobulins

scientific article published on 01 August 1987

Cataloging topologies of protein folding patterns

scientific article published on March 2010

Classification of Protein Function

Comment on “Comparing proteins by their internal dynamics: Exploring structure–function relationships beyond static structural alignments” by C. Micheletti ⬇️

scientific article published on October 26, 2012

Common features of the conformations of antigen-binding loops in immunoglobulins and application to modeling loop conformations

scientific article published in July 1992

Comparison of the structures of globins and phycocyanins: evidence for evolutionary relationship

scientific article

Comprehensive, comprehensible, distributed and intelligent databases: current status

scientific article published in January 1998

Computational study of the fibril organization of polyglutamine repeats reveals a common motif identified in beta-helices

scientific article published on 9 February 2006

Computer modelling of a potential agent against SARS-Cov-2 (COVID-19) protease

scientific article published on 14 July 2020

Computer-generated pictures of proteins

scientific article

Computer-generated schematic diagrams of protein structures

scientific article

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

scientific article

Conformational changes in serpins: I. the native and cleaved conformations of α 1 -antitrypsin 1 1Edited by J. M. Thornton

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

scientific article

Conformations of immunoglobulin hypervariable regions

scientific article

Conformations of the third hypervariable region in the VH domain of immunoglobulins

scientific article

Conservation and variability in the structures of serine proteinases of the chymotrypsin family

scientific article

Contact patterns between helices and strands of sheet define protein folding patterns

scientific article published in March 2007

Correlation of co-ordinated amino acid substitutions with function in viruses related to tobacco mosaic virus

scientific article published in February 1987

Correspondences between low-energy modes in enzymes: dynamics-based alignment of enzymatic functional families

scientific article published on 27 March 2008

Determinants of a protein fold. Unique features of the globin amino acid sequences

scientific article published on 01 July 1987

Does protein structure determine amino acid sequence?

scientific article published in June 1992

Domain closure in lactoferrin. Two hinges produce a see-saw motion between alternative close-packed interfaces

scientific article published on November 1993

Domain closure in mitochondrial aspartate aminotransferase

scientific article

Elbow motion in the immunoglobulins involves a molecular ball-and-socket joint

scientific article published in Nature

Evolution of amino acid frequencies in proteins over deep time: inferred order of introduction of amino acids into the genetic code

scientific article

Evolution of proteins formed by beta-sheets. I. Plastocyanin and azurin

scientific article published on 01 September 1982

Evolution of proteins formed by beta-sheets. II. The core of the immunoglobulin domains

scientific article published on 01 September 1982

Extraction of geometrically similar substructures: least-squares and Chebyshev fitting and the difference distance matrix

scientific article published in November 1998

Extraction of well-fitting substructures: root-mean-square deviation and the difference distance matrix ⬇️

scientific article published on January 1, 1997

Fix L, a haemoglobin that acts as an oxygen sensor: signalling mechanism and structural basis of its homology with PAS domains

scientific article

Folding units in globular proteins

scientific article

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

scientific article published in September 1990

Functional insights from the distribution and role of homopeptide repeat-containing proteins

scientific article

Gathering them in to the fold

scientific article

Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)

scientific article

Haemoglobin: the surface buried between the alpha 1 beta 1 and alpha 2 beta 2 dimers in the deoxy and oxy structures

scientific article published in May 1985

Helix movements and the reconstruction of the haem pocket during the evolution of the cytochrome c family

scientific article published in March 1985

How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins

scientific article

How precise are reported protein coordinate data?

scientific article

Hydrophobicity—getting into hot water ⬇️

scientific article published on September 1, 2003

Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpins

scientific article

Interior and surface of monomeric proteins

scientific article

Intraspecific phylogenetic analysis of Siberian woolly mammoths using complete mitochondrial genomes

scientific article (publication date: 17 June 2008)

MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography

scientific article

MUSTANG: a multiple structural alignment algorithm

scientific article published in August 2006

Macromolecular marionettes

scientific article published on 01 April 1977

Mechanisms of domain closure in proteins

scientific article published on 01 March 1984

Minimum message length inference of secondary structure from protein coordinate data

scientific article

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

scientific article published on 01 November 1996

Modelling Protein Structures

Modularity and homology: modelling of the titin type I modules and their interfaces

article

Molecular biology. Coordination of sequence data

scientific article published on 01 March 1985

Molecular forces in antibody maturation

scientific article published on 10 November 2005

NAD-binding domains of dehydrogenases

scientific article

On Sufficient Statistics of Least-Squares Superposition of Vector Sets

article by Arun S Konagurthu et al published 2014 in Lecture Notes in Computer Science

On hypothesized selective pressure by u.v. on DNA base compositions ⬇️

scientific article published on 01 July 1973

On sufficient statistics of least-squares superposition of vector sets

scientific article published on 19 February 2015

On the origin of distribution patterns of motifs in biological networks

scientific article

On the possibility of a stage in the evolution of the genetic message in which replication was imprecise

scientific article published on 01 March 1970

On the use of overlapping lattices for screening to find pairs of nearby points in two and three dimensions

scientific article published on 12 February 2008

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

scientific article

Piecewise linear approximation of protein structures using the principle of minimum message length

scientific article

Prediction of protein function from protein sequence and structure

scientific article

Preparative induction and characterization of L-antithrombin: a structural homologue of latent plasminogen activator inhibitor-1.

scientific article

Principles determining the structure of beta-sheet barrels in proteins. I. A theoretical analysis

scientific article

Principles determining the structure of beta-sheet barrels in proteins. II. The observed structures

scientific article

Probing protein structure by solvent perturbation of NMR spectra. II. Determination of surface and buried residues in homologous proteins

scientific article

Probing protein structure by solvent perturbation of NMR spectra: the surface accessibility of bovine pancreatic trypsin inhibitor

scientific article

Probing protein structure by solvent perturbation of nuclear magnetic resonance spectra. Nuclear magnetic resonance spectral editing and topological mapping in proteins by paramagnetic relaxation filtering.

scientific article

Protein structural alignments and functional genomics

scientific article published on 01 February 2001

Protein structure, evolution, and conformational change

scientific article

Quantitative sequence-function relationships in proteins based on gene ontology

scientific article

Reinterpretation of Moseley’s experiments relating Kα line frequencies and atomic number

SH3 domains in prokaryotes

scientific article

Sequencing the nuclear genome of the extinct woolly mammoth

scientific article

Serpins in Prokaryotes

Serpins in prokaryotes

scientific article

Serpins in the Caenorhabditis elegans genome

scientific article published on 01 July 1999

Serpins in theCaenorhabditis elegans genome

scholarly article by James C. Whisstock published in July 1999

Single and multiple input modules in regulatory networks

scientific article

Sizes of interface residues account for cross-class binding affinity patterns in Eph receptor-ephrin families

scientific article published on 18 October 2013

Solvent accessibility, protein surfaces, and protein folding

scientific article

Spectroscopic features of nucleic acid evolution

scientific article published on 01 January 1971

Stabilization of the native tertiary structure of yeast tRNALeu3 by cationic metal complexes

scientific article published in October 1975

Standard conformations for the canonical structures of immunoglobulins

scientific article

Statistical Compression of Protein Folding Patterns for Inference of Recurrent Substructural Themes

Statistical Inference of Protein "LEGO Bricks"

Statistical inference of protein structural alignments using information and compression

scientific article published on 8 January 2017

Structural alignment and analysis of two distantly related proteins:Aplysia limacina myoglobin and sea lamprey globin

scholarly article by Annalisa Pastore published in January 1988

Structural determinants of the conformations of medium-sized loops in proteins

scientific article published in January 1989

Structural divergence and distant relationships in proteins: evolution of the globins

scientific article

Structural mechanisms for domain movements in proteins

scientific article

Structural principles of alpha/beta barrel proteins: the packing of the interior of the sheet

scientific article

Structural repertoire of the human VH segments

scientific article published on October 1992

Structure Description and Identification Using the Tableau Representation of Protein Folding Patterns ⬇️

scientific article published on January 1, 2013

Super: a web server to rapidly screen superposable oligopeptide fragments from the protein data bank ⬇️

scientific article published on May 25, 2012

Systematic representation of protein folding patterns ⬇️

scientific article published on June 1, 1995

Tendamistat surface accessibility to the TEMPOL paramagnetic probe.

scientific article

The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site

scientific article

The Computational Analysis of Protein Structures: Sources, Methods, Systems and Results

scientific article (publication date: 1989)

The accessible surface area and stability of oligomeric proteins

scientific article published in Nature

The evolution of protein structures

scientific article published on 01 January 1987

The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition

scientific article

The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus)

scientific article published in February 2009

The outline structure of the T-cell alpha beta receptor.

scientific article published on December 1988

The predicted structure of immunoglobulin D1.3 and its comparison with the crystal structure

scientific article

The relation between the divergence of sequence and structure in proteins

scientific article

The structural repertoire of the human V kappa domain

scientific article

The unreasonable effectiveness of mathematics in molecular biology

scholarly article by Arthur M. Lesk published in March 2000

Three-dimensional searching for recurrent structural motifs in data bases of protein structures

scientific article

Three-dimensional structures of proteins: archives, research and applications

scientific article

Transfer experiments: a plea for tolerance

scientific article

Transmission of conformational change in insulin

scientific article published in Nature

What determines the spectrum of protein native state structures?

scientific article

Why does DNA contain thymine and RNA uracil? ⬇️

scientific article published on 01 March 1969

beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors

scientific article

List of works by Arthur M. Lesk

28-way vertebrate alignment and conservation track in the UCSC Genome Browser

A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry?

A combinatorial study of the effects of admitting non-watson-crick base pairings and of base composition on the helix-forming potential of polynucleotides of random sequence ⬇️

A cross-reference table between the Protein Data Bank of macromolecular structures and the National Biomedical Research Foundation-Protein Identification Resource amino acid sequence data bank

A method for multiple superposition of structures

A tale of two proteinases

Alarums and diversions

Alignment of the amino acid sequences of distantly related proteins using variable gap penalties

Amyloid fibers are water-filled nanotubes

An atlas of serpin conformations.

An encoding technique to facilitate the detection of homologies in biopolymer sequences ⬇️

Antibody modeling: implications for engineering and design.

Antibody structure, prediction and redesign

Application of the common features of transfer RNAs to the determination of their nucleotide sequences ⬇️

Aprés moi lé deluge

Assessment of novel fold targets in CASP4: predictions of three-dimensional structures, secondary structures, and interresidue contacts.

Bioinformatics of Protein Function

Brave new proteins: what evolution reveals about protein structure.

CASP2: Report on ab initio predictions ⬇️

Canonical structures for the hypervariable regions of T cell alphabeta receptors

Canonical structures for the hypervariable regions of immunoglobulins

Cataloging topologies of protein folding patterns

Classification of Protein Function

Comment on “Comparing proteins by their internal dynamics: Exploring structure–function relationships beyond static structural alignments” by C. Micheletti ⬇️

Common features of the conformations of antigen-binding loops in immunoglobulins and application to modeling loop conformations

Comparison of the structures of globins and phycocyanins: evidence for evolutionary relationship

Comprehensive, comprehensible, distributed and intelligent databases: current status

Computational study of the fibril organization of polyglutamine repeats reveals a common motif identified in beta-helices

Computer modelling of a potential agent against SARS-Cov-2 (COVID-19) protease

Computer-generated pictures of proteins

Computer-generated schematic diagrams of protein structures

Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin

Conformational changes in serpins: I. the native and cleaved conformations of α 1 -antitrypsin 1 1Edited by J. M. Thornton

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

Conformations of immunoglobulin hypervariable regions

Conformations of the third hypervariable region in the VH domain of immunoglobulins

Conservation and variability in the structures of serine proteinases of the chymotrypsin family

Contact patterns between helices and strands of sheet define protein folding patterns

Correlation of co-ordinated amino acid substitutions with function in viruses related to tobacco mosaic virus

Correspondences between low-energy modes in enzymes: dynamics-based alignment of enzymatic functional families

Determinants of a protein fold. Unique features of the globin amino acid sequences

Does protein structure determine amino acid sequence?

Domain closure in lactoferrin. Two hinges produce a see-saw motion between alternative close-packed interfaces

Domain closure in mitochondrial aspartate aminotransferase

Elbow motion in the immunoglobulins involves a molecular ball-and-socket joint

Evolution of amino acid frequencies in proteins over deep time: inferred order of introduction of amino acids into the genetic code

Evolution of proteins formed by beta-sheets. I. Plastocyanin and azurin

Evolution of proteins formed by beta-sheets. II. The core of the immunoglobulin domains

Extraction of geometrically similar substructures: least-squares and Chebyshev fitting and the difference distance matrix

Extraction of well-fitting substructures: root-mean-square deviation and the difference distance matrix ⬇️

Fix L, a haemoglobin that acts as an oxygen sensor: signalling mechanism and structural basis of its homology with PAS domains

Folding units in globular proteins

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

Functional insights from the distribution and role of homopeptide repeat-containing proteins

Gathering them in to the fold

Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)

Haemoglobin: the surface buried between the alpha 1 beta 1 and alpha 2 beta 2 dimers in the deoxy and oxy structures

Helix movements and the reconstruction of the haem pocket during the evolution of the cytochrome c family

How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins

How precise are reported protein coordinate data?

Hydrophobicity—getting into hot water ⬇️

Importance of the release of strand 1C to the polymerization mechanism of inhibitory serpins

Interior and surface of monomeric proteins

Intraspecific phylogenetic analysis of Siberian woolly mammoths using complete mitochondrial genomes

MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography

MUSTANG: a multiple structural alignment algorithm

Macromolecular marionettes

Mechanisms of domain closure in proteins

Minimum message length inference of secondary structure from protein coordinate data

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

Modelling Protein Structures

Modularity and homology: modelling of the titin type I modules and their interfaces

Molecular biology. Coordination of sequence data

Molecular forces in antibody maturation

NAD-binding domains of dehydrogenases

On Sufficient Statistics of Least-Squares Superposition of Vector Sets

On hypothesized selective pressure by u.v. on DNA base compositions ⬇️

On sufficient statistics of least-squares superposition of vector sets

On the origin of distribution patterns of motifs in biological networks