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List of works by Manel Juan

A SNP in intron 1 of TSHR controls its thymic expression and susceptibility to Graves’ disease suggesting central tolerance failure in pathogenesis.

scientific article published on 23 November 2011

A somatic NLRP3 mutation as a cause of a sporadic case of chronic infantile neurologic, cutaneous, articular syndrome/neonatal-onset multisystem inflammatory disease: Novel evidence of the role of low-level mosaicism as the pathophysiologic mechanis

scientific article published in April 2010

Adult peripheral blood and umbilical cord blood NK cells are good sources for effective CAR therapy against CD19 positive leukemic cells

scientific article published on 10 December 2019

Androgen Receptor and Its Splicing Variant 7 Expression in Peripheral Blood Mononuclear Cells and in Circulating Tumor Cells in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 14 January 2020

Association between PD1 mRNA and response to anti-PD1 monotherapy across multiple cancer types

scientific article published on 01 October 2018

Association of Polymorphisms in IRAK1, IRAK4 and MyD88, and Severe Invasive Pneumococcal Disease

scientific article

Association of an SNP with intrathymic transcription of TSHR and Graves' disease: a role for defective thymic tolerance.

scientific article published on 3 June 2011

B Regulatory Cells: Players in Pregnancy and Early Life

scientific article published on 19 July 2018

B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

scientific article

BglII and EcoRI polymorphism of the human nm23-H1 gene (NME1).

scientific article published on December 1991

CAR-T Cell Therapy: A Door Is Open to Find Innumerable Possibilities of Treatments for Cancer Patients

scientific article published on 06 September 2018

CART manufacturing process and reasons for academy-pharma collaboration

scientific article published on 25 October 2019

CCL4L Polymorphisms and CCL4/CCL4L Serum Levels Are Associated with Psoriasis Severity

scientific article published in September 2011

CCL4L polymorphisms and serum levels are associated with psoriasis severity

scientific article published on 25 November 2010

CD34+CD19−CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

scientific article published in 2022

CD50 (intercellular adhesion molecule-3) is expressed at higher levels on memory than on naive human T cells but induces a similar calcium mobilization on both subsets.

scientific article

CDw50 and ICAM-3: two names for the same molecule.

scientific article

Characterization of a monoclonal IgMK (IgMGAS) anti-Gd cold agglutinin (CA). Its coexistence with a monoclonal IgG3K (IgGGAS) without CA activity that might be clonally related to IgMGAS.

scientific article published in March 1994

Characterization of the Highly Prevalent Regulatory CD24hiCD38hi B-Cell Population in Human Cord Blood

scientific article published on 07 March 2017

Chemokines determine local lymphoneogenesis and a reduction of circulating CXCR4+ T and CCR7 B and T lymphocytes in thyroid autoimmune diseases.

scientific article

Chimeric Antigen Receptor T Cells Targeting CD19 and Ibrutinib for Chronic Lymphocytic Leukemia

scientific article published on 08 February 2019

Clues to management of neonatally diagnosed BTK deficiency.

scientific article

Combined analysis of levels of serum B-cell activating factor and a proliferation-inducing ligand as predictor of disease progression in patients with chronic lymphocytic leukemia.

scientific article

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation

article

Comparison of the sensitization profile between children and adults allergic to multiple plant-foods.

scientific article published on 25 July 2013

Copy number variation in chemokine superfamily: the complex scene of CCL3L-CCL4L genes in health and disease.

scientific article published on 19 August 2010

Copy number variation in the CCL4L gene is associated with susceptibility to acute rejection in lung transplantation

article

Correction: Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon

scientific article

Corrigendum: Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma.

scientific article published on 5 June 2018

Cutaneous angiolymphoid hyperplasia with high endothelial venules is characterized by endothelial expression of cutaneous lymphocyte antigen

scientific article published on 01 February 2001

Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmatics

scientific article published on 01 July 1999

DNA demethylation of inflammasome-associated genes is enhanced in patients with cryopyrin-associated periodic syndromes.

scientific article published on 6 July 2016

Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes

scientific article

Detection of inflammatory monocytes but not mesenchymal stem/stromal cells in peripheral blood of patients with myelofibrosis

scientific article published on 21 February 2017

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions

scientific article published on 06 December 2018

Development of a new HLA-DRB real-time PCR typing method.

scientific article published in January 2005

Dithiothreitol sensitivity versus autoreactivity in sera from hypersensitized patients

scientific article published on 01 February 1992

Dynamic pattern of endothelial cell adhesion molecule expression in muscle and perineural vessels from patients with classic polyarteritis nodosa

scientific article published on 01 March 1998

Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with </=250/microL CD4 T cells and undetectable plasma virus load

scientific article published in July 1999

Estradiol enhances endothelial cell interactions with extracellular matrix proteins via an increase in integrin expression and function.

scientific article

Evaluating the Genetics of Common Variable Immunodeficiency: Monogenetic Model and Beyond.

scientific article published on 14 May 2018

Evans Syndrome as First Manifestation of Primary Immunodeficiency in Clinical Practice

scientific article published in October 2017

Existence of a soluble form of CD50 (intercellular adhesion molecule-3) produced upon human lymphocyte activation. Present in normal human serum and levels are increased in the serum of systemic lupus erythematosus patients

scientific article published on 01 March 1995

Expression of intercellular adhesion molecule-3 (ICAM-3/CD50) in malignant lymphoproliferative disorders and solid tumors

scientific article published on 01 October 1996

Expression of the human glucocorticoid receptor alpha and beta isoforms in human respiratory epithelial cells and their regulation by dexamethasone.

scientific article

Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways.

scientific article published in October 1999

Frequency of Antineutrophil Cytoplasmic Antibody in Graves’ Disease Patients Treated with Methimazole ⬇️

scientific article published on May 1, 2003

Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis

article

Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling

scientific article published on 14 February 2019

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

scientific article

Humoral deficiency in three paediatric patients with genetic diseases

scientific article published on 29 February 2016

Immune tolerance in multiple sclerosis and neuromyelitis optica with peptide-loaded tolerogenic dendritic cells in a phase 1b trial

article

Immunological Changes in Blood of Newborns Exposed to Anti-TNF-α during Pregnancy

scientific article published on 21 September 2017

Immunophenotypic analysis and quantification of B-1 and B-2 B cells during human fetal hematopoietic development.

scientific article published on 29 December 2015

Impact on the immune system of undetectable plasma HIV-1 RNA for more than 2 years

scientific article published in May 1998

Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.

scientific article published on 23 February 2014

Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus

scientific article published on 24 October 2005

Isolation of two CD50 (ICAM-3)-negative Jurkat T-cell clones and their application for analysis of CD50 function.

scientific article published in May 1998

Jug r 2-reactive CD4(+) T cells have a dominant immune role in walnut allergy

scientific article

Kinetic analysis of changes in T- and B-lymphocytes after anti-CD20 treatment in renal pathology.

scientific article published on 17 November 2016

LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population

scientific article

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma.

scientific article published on 21 October 2013

Lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant-foods and pollens

article

Massively parallel sequencing reveals maternal somatic IL2RG mosaicism in an X-linked severe combined immunodeficiency family.

scientific article published on 15 May 2013

Multi-level immune response network in mild-moderate Chronic Obstructive Pulmonary Disease (COPD)

scientific article published on 12 July 2019

Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients

scientific article published on 01 May 2005

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome

scientific article published on 29 April 2014

Neutrophil and Monocyte Function in Patients with Chronic Hepatitis C Undergoing Antiviral Therapy with Regimens Containing Protease Inhibitors with and without Interferon.

scientific article

Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: Report from the 17th International HLA and Immunogenetics Workshop

scientific article published on 04 March 2019

Nonsteroidal anti-inflammatory drugs enhance IgE-mediated activation of human basophils in patients with food anaphylaxis dependent on and independent of nonsteroidal anti-inflammatory drugs.

scientific article

Novel and atypical splicing mutation in a compound heterozygous UNC13D defect presenting in Familial Hemophagocytic Lymphohistiocytosis triggered by EBV infection

scientific article published on 10 May 2014

One-tube-PCR technique for CCL2, CCL3, CCL4 and CCL5 applied to fine needle aspiration biopsies shows different profiles in autoimmune and non-autoimmune thyroid disorders

scientific article published on 01 April 2006

Population structure in copy number variation and SNPs in the CCL4L chemokine gene

scientific article published on 27 March 2008

Preclinical development of a humanized chimeric antigen receptor against B cell maturation antigen for multiple myeloma

scientific article published on 09 January 2020

Prevalence and clinical relevance of low levels of Pru p 3 specific IgE in patients with peach sensitization

scientific article

Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.

scientific article

Pyogenic bacterial infections in humans with MyD88 deficiency

scientific article

Real-time PCR using fluorescent resonance emission transfer probes for HLA-B typing.

scientific article

Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.

scientific article

Recurrent invasive pneumococcal disease in children: underlying clinical conditions, and immunological and microbiological characteristics

scientific article

RsaI polymorphism of the human CD27 gene, a member of nerve growth factor receptor gene family

scientific article

Severe BCG-osis Misdiagnosed as Multidrug-Resistant Tuberculosis in an IL-12Rβ1-Deficient Peruvian Girl

scholarly article by Ana Esteve-Sole et al published 23 July 2018 in Journal of Clinical Immunology

Signaling through CD50 (ICAM-3) stimulates T lymphocyte binding to human umbilical vein endothelial cells and extracellular matrix proteins via an increase in β1 and β2 integrin function

scientific article published on 01 June 1994

Single-cycle rituximab-induced immunologic changes in children: Enhanced in neuroimmunologic disease?

scientific article published on 06 May 2020

Sirolimus as an alternative treatment in patients with granulomatous-lymphocytic lung disease and humoral immunodeficiency with impaired regulatory T cells.

scientific article published on 12 March 2018

Stimulation through CD50 (ICAM-3) induces both activation and programmed cell death of human thymocytes.

scientific article published on December 1996

Targeting IRAK4 disrupts inflammatory pathways and delays tumor development in chronic lymphocytic leukemia

scientific article published on 13 June 2019

The chemokine network. I. How the genomic organization of chemokines contains clues for deciphering their functional complexity. ⬇️

scientific article published on May 2007

The inflammasome pathway in stable COPD and acute exacerbations

scientific article

Toll-like receptor 3 deficiency in autoimmune encephalitis post-herpes simplex encephalitis

scientific article published on 05 September 2019

Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens

scientific article published on 01 December 1998

Type I leucocyte adhesion deficiency (LAD I). Report of a case.

scientific article

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

scientific article (publication date: 5 June 2011)

[Reduction of hematogenous infection in HIV positive patients following highly active antiretroviral therapy]

scientific article published on 01 February 2001

mTOR intersects antibody-inducing signals from TACI in marginal zone B cells

scientific article published on 13 November 2017

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