List of works - Gang Liu

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment

scientific article

ATF4 Mediates Mitochondrial Unfolded Protein Response (UPRmt) in Alveolar Epithelial Cells

scientific article published on 18 June 2020

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.

scientific article published on 27 June 2008

Airway PI3K pathway activation is an early and reversible event in lung cancer development

scientific article published on April 2010

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

article

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

scientific article published on 07 August 2013

Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.

scientific article published on 16 January 2009

Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data

scientific article

Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis

scientific article

Cellular Metabolism in Lung Health and Disease

scientific article published on 28 November 2018

Characterization of p73 functional domains necessary for transactivation and growth suppression

scientific article published on 01 July 2003

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

scientific article published on 11 December 2019

DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.

scientific article

DeltaNp73beta is active in transactivation and growth suppression.

scientific article published on January 2004

Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial

scientific article published on 26 August 2019

Effects of cigarette smoke on the human airway epithelial cell transcriptome

scholarly article

Extracellular histones inhibit efferocytosis.

scientific article

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.

scientific article published on 26 July 2017

Gene expression profiling of human lung tissue from smokers with severe emphysema

scientific article published on 16 September 2004

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

scientific article

Glutaminolysis Promotes Collagen Translation and Stability via α-ketoglutarate Mediated mTOR Activation and Proline Hydroxylation

scientific article published on 11 October 2017

High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine

scientific journal article

IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages

scientific article published on 21 March 2018

IL-13 induces YY1 through the AKT pathway in lung fibroblasts.

scientific article

Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells ⬇️

scientific article published on May 9, 2012

Identification of a microRNA signature in renal fibrosis: role of miR-21.

scientific article

Impact of cigarette smoke on the normal airway transcriptome

scientific article published in May 2004

Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury

scientific article published on 01 February 2019

Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.

scientific article published on 13 July 2009

Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis

scientific article published on 01 October 2019

Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.

scientific article

Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

scientific article

Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities

scientific article published on 16 August 2015

Intracellular HMGB1 negatively regulates efferocytosis

scientific article published on 28 September 2011

Involvement of vitronectin in lipopolysaccaride-induced acute lung injury

scientific article published on 01 November 2007

Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury

scientific article published on 21 February 2019

Lung Myofibroblast Promote Macrophage Pro-fibrotic Activity Through Lactate-induced Histone Lactylation

scientific article published on 19 October 2020

Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis

scientific article published on 18 August 2016

Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation.

scientific article

MicroRNA let-7c regulates macrophage polarization.

scientific article published on 10 May 2013

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

scholarly article

MicroRNAs for osteosarcoma in the mouse: a meta-analysis

scientific article

MicroRNAs in immune response and macrophage polarization.

scientific article published on February 2013

Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide

scientific article

Myosin VI is a mediator of the p53-dependent cell survival pathway.

scientific article

Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality ⬇️

scientific article published on May 20, 2013

Noninvasive imaging of experimental lung fibrosis

scientific article

Noninvasive method for obtaining RNA from buccal mucosa epithelial cells for gene expression profiling.

scientific article

Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.

scientific article published on 08 January 2009

Participation of miR-200 in Pulmonary Fibrosis ⬇️

scientific article published on December 20, 2011

Participation of the receptor for advanced glycation end products in efferocytosis

scientific article published on 18 April 2011

Participation of the urokinase receptor in neutrophil efferocytosis.

scientific article published on 27 April 2009

Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.

scientific article

Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice

scientific article

Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

scientific article published on 24 July 2008

Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism

scientific article published on 11 May 2015

Regulation of alveolar epithelial Na+ channels by ERK1/2 in chlorine-breathing mice

scientific article published on 13 October 2011

Regulation of the p53 transcriptional activity.

scientific article

Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase.

scientific article

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression

scientific article published on January 2007

Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production.

scientific article

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue

scientific article published on 17 September 2012

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

scientific article

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

scientific article

The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis.

scientific article

The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73.

scientific article

The Lung Likes the Little Fella miR-29.

scientific article published in December 2017

The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.

scientific article published on 27 February 2003

The code of non-coding RNAs in lung fibrosis

scientific article

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

scientific article (publication date: 17 October 2002)

The human long noncoding RNA lnc-IL7R regulates the inflammatory response

scientific article

The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.

scientific article

The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils

scientific article

miR-125a-5p regulates differential activation of macrophages and inflammation.

scientific article published on 22 October 2013

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses.

scholarly article

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

scientific article

miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling

scientific article published on 6 February 2013

miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling.

scientific article published on 6 January 2012

miR-27a regulates inflammatory response of macrophages by targeting IL-10.

scientific article published on 16 May 2014

miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.

scientific article

miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence

scientific article

miR‐145 regulates myofibroblast differentiation and lung fibrosis ⬇️

scientific article published on March 1, 2013

microRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia.

scientific article published on 12 December 2017

ncRNA-regulated immune response and its role in inflammatory lung diseases

scientific article

p53 Attenuates lipopolysaccharide-induced NF-kappaB activation and acute lung injury.

scientific article published in April 2009

p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.

scientific article

List of works by Gang Liu

A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment

ATF4 Mediates Mitochondrial Unfolded Protein Response (UPRmt) in Alveolar Epithelial Cells

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.

Airway PI3K pathway activation is an early and reversible event in lung cancer development

Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.

Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data

Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis

Cellular Metabolism in Lung Health and Disease

Characterization of p73 functional domains necessary for transactivation and growth suppression

Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution

DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.

DeltaNp73beta is active in transactivation and growth suppression.

Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial

Effects of cigarette smoke on the human airway epithelial cell transcriptome

Extracellular histones inhibit efferocytosis.

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.

Gene expression profiling of human lung tissue from smokers with severe emphysema

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

Glutaminolysis Promotes Collagen Translation and Stability via α-ketoglutarate Mediated mTOR Activation and Proline Hydroxylation

High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine

IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages

IL-13 induces YY1 through the AKT pathway in lung fibroblasts.

Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells ⬇️

Identification of a microRNA signature in renal fibrosis: role of miR-21.

Impact of cigarette smoke on the normal airway transcriptome

Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury

Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.

Inhibition of Glutaminase 1 Attenuates Experimental Pulmonary Fibrosis

Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.

Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities

Intracellular HMGB1 negatively regulates efferocytosis

Involvement of vitronectin in lipopolysaccaride-induced acute lung injury

Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury

Lung Myofibroblast Promote Macrophage Pro-fibrotic Activity Through Lactate-induced Histone Lactylation

Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis

Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation.

MicroRNA let-7c regulates macrophage polarization.

MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium

MicroRNAs for osteosarcoma in the mouse: a meta-analysis

MicroRNAs in immune response and macrophage polarization.

Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide

Myosin VI is a mediator of the p53-dependent cell survival pathway.

Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, senescence, and radiation-induced mortality ⬇️

Noninvasive imaging of experimental lung fibrosis

Noninvasive method for obtaining RNA from buccal mucosa epithelial cells for gene expression profiling.

Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.

Participation of miR-200 in Pulmonary Fibrosis ⬇️

Participation of the receptor for advanced glycation end products in efferocytosis

Participation of the urokinase receptor in neutrophil efferocytosis.

Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.

Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice

Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism

Regulation of alveolar epithelial Na+ channels by ERK1/2 in chlorine-breathing mice

Regulation of the p53 transcriptional activity.

Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase.

Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression

Role of extracellular superoxide in neutrophil activation: interactions between xanthine oxidase and TLR4 induce proinflammatory cytokine production.

SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium

The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis.

The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73.

The Lung Likes the Little Fella miR-29.

The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.

The code of non-coding RNAs in lung fibrosis

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

The human long noncoding RNA lnc-IL7R regulates the inflammatory response

The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.

The receptor for urokinase regulates TLR2 mediated inflammatory responses in neutrophils

miR-125a-5p regulates differential activation of macrophages and inflammation.

miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses.

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling

miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling.

miR-27a regulates inflammatory response of macrophages by targeting IL-10.