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List of works by Eva Nogales

A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation

scientific article published on 08 October 2013

A new protocol to accurately determine microtubule lattice seam location

scientific article

A revised nomenclature for the human and rodent alpha-tubulin gene family

scientific article published in June 2007

A unique supramolecular organization of photosystem I in the moss Physcomitrella patens

scientific article published on 29 October 2018

ATP ground- and transition states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, sigma54.

scientific article published on April 2007

Ab initio reconstruction of helical samples with heterogeneity, disorder and coexisting symmetries

scientific article published on 15 May 2009

An electron microscopy journey in the study of microtubule structure and dynamics

scientific article published on 24 September 2015

An iterative Fourier-Bessel algorithm for reconstruction of helical structures with severe Bessel overlap

scientific article published on January 2005

Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

scientific article

Architecture and flexibility of the yeast Ndc80 kinetochore complex

scientific article published on 05 September 2008

Architecture of human translation initiation factor 3.

scientific article published on 25 April 2013

Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms

scientific article published on 22 July 2007

Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement

scientific article published on 30 December 2019

Architecture of the human XPC DNA repair and stem cell coactivator complex

scientific article

Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing

scientific article

Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine

scientific article published on 20 September 2005

Assembly, molecular organization, and membrane-binding properties of development-specific septins

scientific article published on February 2016

Atomic force microscopy of photosystem II and its unit cell clustering quantitatively delineate the mesoscale variability in Arabidopsis thylakoids

scientific article

Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors

scientific article published on 01 April 2019

Automated multi-model reconstruction from single-particle electron microscopy data

scientific article

Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner

scientific article published on 14 March 2007

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference

scientific article

CasX enzymes comprise a distinct family of RNA-guided genome editors

scientific article published on 04 February 2019

Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners

scientific article published on 16 June 2017

Characterization of Septin Ultrastructure in Budding Yeast Using Electron Tomography

scientific article published in January 2016

Chloroplast Sec14-like 1 (CPSFL1) is essential for normal chloroplast development and affects carotenoid accumulation in Chlamydomonas

scientific article published on 13 May 2020

Comparative studies of microtubule mechanics with two competing models suggest functional roles of alternative tubulin lateral interactions

scientific article

Complete subunit architecture of the proteasome regulatory particle ⬇️

scientific article published on January 11, 2012

Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method

scientific article

Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae

scientific article published on 18 May 2016

Correction: Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

scientific article published on 21 October 2015

Corrigendum to “A revised nomenclature for the human and rodent α-tubulin gene family” [Genomics 90 (2007) 285–289]

scientific article published in April 2009

Corrigendum: Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

scientific article published on 20 April 2016

Cross-correlation of common lines: A novel approach for single-particle reconstruction of a structure containing a flexible domain

scientific article (publication date: September 2007)

Cryo-EM

scientific article published on 01 October 2018

Cryo-EM in the study of challenging systems: the human transcription pre-initiation complex

scientific article

Cryo-EM structure of substrate-bound human telomerase holoenzyme.

scientific article published on 25 April 2018

Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes.

scientific article

Cryo-EM studies of NAIP-NLRC4 inflammasomes

scientific article published on 24 May 2019

Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions

scientific article

Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity

scientific article published on May 2015

Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues

scientific article

Cryoelectron Microscopy Applications in the Study of Tubulin Structure, Microtubule Architecture, Dynamics and Assemblies, and Interaction of Microtubules with Motors ⬇️

scientific article published on January 1, 2010

Current outcomes when optimizing 'standard' sample preparation for single-particle cryo-EM

scientific article published on 07 October 2019

Cytoskeleton in high resolution

scientific article published on 24 January 2018

DNA Targeting by a Minimal CRISPR RNA-Guided Cascade

scientific article published on September 2016

DNA interference states of the hypercompact CRISPR-CasΦ effector

scientific article published on 11 August 2021

Dear microtubule, I see you

scientific article

Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore

scientific article

Disabling Cas9 by an anti-CRISPR DNA mimic

scientific article

Disabling Cas9 by an anti-CRISPR DNA mimic

Dynamic mechanical responses of Arabidopsis thylakoid membranes during PSII-specific illumination

scientific article

Effects of Bni5 Binding on Septin Filament Organization

scientific article

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure

scientific article

Effects of α-tubulin acetylation on microtubule structure and stability

Effects of α-tubulin acetylation on microtubule structure and stability.

scientific article

Electron microscopy visualization of DNA-protein complexes formed by Ku and DNA ligase IV

scientific article published on 15 November 2011

Enhanced FIB-SEM systems for large-volume 3D imaging

scientific article

Eva Nogales: See how they run.

scientific article published on May 2015

Flexible tethering of primase and DNA Pol in the eukaryotic primosome

Flexible tethering of primase and DNA Pol α in the eukaryotic primosome.

scientific article

Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex

scientific article

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3) ⬇️

scientific article published on December 20, 2011

Go hybrid: EM, crystallography, and beyond ⬇️

scientific article published on July 24, 2012

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

scientific article

High-resolution cryo-EM structures of TFIIH and their functional implications

scientific article published on 07 October 2019

How Cryo-EM Became so Hot.

scientific article published in November 2017

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

scientific article

Human TFIID binds to core promoter DNA in a reorganized structural state

scientific article published on January 2013

In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release

scientific article

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

scientific article published on 16 January 2017

Maximum likelihood refinement of electron microscopy data with normalization errors

scientific article

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

scientific article

Microtubule dynamics

scientific article

Microtubule structure at 8 A resolution

scientific article published on 01 October 2002

Microtubules: 50 years on from the discovery of tubulin

scientific article published on April 2016

Molecular architecture and conformational flexibility of human RNA polymerase II.

scientific article published on November 2006

Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex

scientific article

Molecular architecture of human polycomb repressive complex 2

scientific article published in 2012

Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly

scientific article

Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes

scientific article published on 31 December 2012

Multimodal microtubule binding by the Ndc80 kinetochore complex

scientific article

Multiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts ⬇️

scientific article published on February 8, 2012

Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends

scientific article published on April 2016

Mutations in TUBB8 and Human Oocyte Meiotic Arrest

scientific journal article

My Dream of a Fantastic Voyage to See the Inner Workings of a Cell ⬇️

scientific article published on November 15, 2010

Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins

scientific article published on 19 August 2013

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

scientific article published on 04 August 2016

Near-atomic model of microtubule-tau interactions

scientific article published on 10 May 2018

Near-atomic resolution visualization of human transcription promoter opening

scientific article

New technologies in imaging

scientific article published in March 2013

Next-generation electron microscopy in autophagy research

scientific article published on 7 September 2016

Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly

scientific article

Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex.

scientific article published on 9 July 2006

Octomeric pyruvate-ferredoxin oxidoreductase from Desulfovibrio vulgaris

scientific article published on 17 February 2007

Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization

scientific article

Profile of Joachim Frank, Richard Henderson, and Jacques Dubochet, 2017 Nobel Laureates in Chemistry

scientific article published in December 2017

Protein domain mapping by internal labeling and single particle electron microscopy

scientific article published on 29 September 2015

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus

scientific article

Ranking TEM cameras by their response to electron shot noise

scientific article

Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding

scientific article published on 03 December 2018

Recent insights into the structure of TFIID, its assembly, and its binding to core promoter

scientific article published on 18 November 2019

Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome

scientific article

Regulatory interplay between TFIID's conformational transitions and its modular interaction with core promoter DNA.

scientific article

Remote control of myosin and kinesin motors using light-activated gearshifting

scientific article

Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability

scientific article

Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly

scientific article

Separating the effects of nucleotide and EB binding on microtubule structure.

scientific article published on 18 June 2018

Septin Filament Formation Is Essential in Budding Yeast ⬇️

scientific article published on April 19, 2011

Septin filament organization in Saccharomyces cerevisiae

scientific article

Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly

scientific article

Single particle EM studies of the Drosophila melanogaster origin recognition complex and evidence for DNA wrapping

scientific article published on 11 September 2008

Structural Insights into the Eukaryotic Transcription Initiation Machinery

scientific article published on May 2017

Structural and functional differences between porcine brain and budding yeast microtubules.

scientific article published on 26 December 2017

Structural basis for dimerization quality control

scientific article published on 19 August 2020

Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning

scientific article

Structural changes in TAF4b-TFIID correlate with promoter selectivity

scientific article

Structural differences between yeast and mammalian microtubules revealed by cryo-EM.

scientific article published on 26 June 2017

Structural dynamics and DNA interaction of human TFIID.

scientific article published on 09 December 2016

Structural insight into TPX2-stimulated microtubule assembly.

scientific article published on 9 November 2017

Structural insights into RNA processing by the human RISC-loading complex

scientific article

Structural insights into transcriptional repression by noncoding RNAs that bind to human Pol II

scientific article published on 4 September 2012

Structural intermediates in microtubule assembly and disassembly: how and why?

scientific article

Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives

scientific article

Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5

scientific article

Structural roles for human translation factor eIF3 in initiation of protein synthesis

scientific article

Structural studies of the human PBAF chromatin-remodeling complex

scientific article

Structural visualization of key steps in human transcription initiation ⬇️

scientific article published on February 27, 2013

Structure and flexibility of the yeast NuA4 histone acetyltransferase complex

scientific article published in 2022

Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription

scientific article

Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts

scientific article published on 28 October 2019

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

scientific article

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

scientific journal article

Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ

scientific article

Structure of the human SAGA coactivator complex

scientific article published on 22 November 2021

Structure, function, and activator-induced conformations of the CRSP coactivator

scientific article

Structure-function insights into the yeast Dam1 kinetochore complex

scientific article

Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

scientific article

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

scientific article

Structures of human PRC2 with its cofactors AEBP2 and JARID2.

scientific article

Structures of the CRISPR genome integration complex

scientific article

Structures of the RNA-guided surveillance complex from a bacterial immune system

scientific article

Structures of three distinct activator-TFIID complexes

scientific article published on July 2009

Substrate-specific structural rearrangements of human Dicer

scientific article published on 28 April 2013

Subunit organization in the Dam1 kinetochore complex and its ring around microtubules ⬇️

scientific article published on September 30, 2011

Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation

scientific article published on 5 December 2011

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

scientific article

Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag

scientific article

Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble

scientific article published on 05 July 2019

Telomerase structures and regulation: shedding light on the chromosome end

scientific article published on 01 April 2019

Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

scientific article published on 27 December 2018

The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends.

scientific article published on 15 January 2006

The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule ⬇️

scientific article published on December 17, 2010

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules

scientific article

The Structures of Eukaryotic Transcription Pre-initiation Complexes and Their Functional Implications

scientific article published on 01 January 2019

The complete structure of the human TFIIH core complex

scientific article published on 12 March 2019

The cryo-electron microscopy structure of human transcription factor IIH.

scientific article published on 13 September 2017

The cryoelectron microscopy structure of the human CDK-activating kinase

scientific article published on 27 August 2020

The development of cryo-EM into a mainstream structural biology technique

scientific article published on January 2016

The gammaherpesviral TATA-box-binding protein directly interacts with the CTD of host RNA Pol II to direct late gene transcription

scientific article published on 04 September 2020

The microtubule binding properties of CENP-E's C-terminus and CENP-F.

scientific article published on 25 July 2013

The orthogonal tilt reconstruction method: an approach to generating single-class volumes with no missing cone for ab initio reconstruction of asymmetric particles

scientific article published on 21 December 2005

The proteasome under the microscope: the regulatory particle in focus

scientific article

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

scientific article

The structural basis for regulated assembly and function of the transcriptional activator NtrC.

scientific article

The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.

scientific article

Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae

scientific article published on 7 December 2011

Towards a mechanistic understanding of core promoter recognition from cryo-EM studies of human TFIID.

scientific article

Tubulin rings: which way do they curve?

scientific article

Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability

scientific article

Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation

scientific journal article

Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions

scientific article published on January 2007

Visualizing kinetochore architecture

scientific article

Visualizing microtubule structural transitions and interactions with associated proteins

scientific article published on 21 January 2016

When cytoskeletal worlds collide

scientific article

Who mentors whom?

scientific article published on 01 November 2018

XKCM1 acts on a single protofilament and requires the C terminus of tubulin

scientific article

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