List of works by Nancy Andrews

2002 E. Mead Johnson Award for Research in Pediatrics Lecture: the molecular biology of the anemia of chronic disease: a hypothesis

scientific article published in March 2003

A genetic view of iron homeostasis

scientific article

A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency

scientific journal article

A mouse model of juvenile hemochromatosis

scientific article

A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice

scientific article

A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase

scientific journal article

A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway

scientific article

ABCs of erythroid mitochondrial iron uptake

scientific article published on 15 September 2009

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

scientific article published on 18 April 2004

An Iron-Clad Role for Proteasomal Degradation

scientific article published on 01 September 2011

Analysis of the E399D mutation in SLC11A2

scientific article published on 01 September 2005

Anemia of inflammation: the cytokine-hepcidin link

scientific article

Anemia of inflammation: the cytokine-hepcidin link

Anemia of inflammation: the hepcidin link

scientific article (publication date: March 2005)

Animal models of hereditary iron transport disorders

scientific article

Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) gene

article

Balancing acts: molecular control of mammalian iron metabolism

scientific article (publication date: 30 April 2004)

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

scientific article

Build it and hope that enough of them will come

scientific article (publication date: October 2009)

Can we keep the "academic" in academic medicine? 2009 American Society for Clinical Investigation Presidential Address

scientific article published on 14 December 2009

Case records of the Massachusetts General Hospital. Case 21-2005. A four-week-old male infant with jaundice and thrombocytopenia

scientific article

Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice

scientific article

Climbing through medicine's glass ceiling

scientific article published in November 2007

Closing the iron gate.

scientific article published in January 2012

Commentary on

scientific article published on 01 September 1999

Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus

scientific article

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

scientific article published on 01 May 2003

Contributions of beta2-microglobulin-dependent molecules and lymphocytes to iron regulation: insights from HfeRag1(-/-) and beta2mRag1(-/-) double knock-out mice

scientific article published on 4 December 2003

Control of Systemic Iron Homeostasis by the 3' Iron-Responsive Element of Divalent Metal Transporter 1 in Mice

scientific article published on 23 September 2020

Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice

scientific article published on 16 June 2005

Deficiency of heme-regulated eIF2alpha kinase decreases hepcidin expression and splenic iron in HFE-/- mice

scientific article

Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis

scientific article published on October 2008

Disorders of iron metabolism

scientific article (publication date: 23 December 1999)

Disorders of iron metabolism

scientific article (publication date: 27 April 2000)

Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice

scientific article published on 29 February 2016

Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines

article

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis

scientific article

Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells.

scientific article

Enhanced expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor receptor subunits in murine hematopoietic cells stimulated with hematopoietic growth factors ⬇️

scientific article published on September 1, 1992

Erratum: Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2

scientific article published in Nature

Erythroid transcription factor NF-E2 coordinates hemoglobin synthesis

scientific article published on October 1994

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.

scientific article

Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.

scientific article published in March 2002

Ferrit(in)ing Out New Mechanisms in Iron Homeostasis

scientific article published on 01 September 2010

Folic acid use by women receiving routine gynecologic care.

scientific article published in April 2004

Forging a field: the golden age of iron biology

scientific article published on July 2008

Genes determining blood cell traits

article

Genes that modify the hemochromatosis phenotype in mice

scientific article

Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice

scientific journal article

Haptoglobin modifies the hemochromatosis phenotype in mice

scientific article published on 21 December 2004

Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression

scientific article published on 13 June 2008

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

scientific article published on 11 January 2007

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

scientific article

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

scientific article

Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice.

scientific article

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

scientific journal article

Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin

scientific article

Hungry irony

scientific article published on 24 August 2015

Identification of a novel mutation (C321X) in HJV.

scientific article

In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction ⬇️

scientific article published on May 1, 1992

Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease

scientific article (publication date: 15 November 2002)

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

scientific article published on 13 February 2007

Inherited iron overload disorders

scientific article

Interleukin-6 induces hepcidin expression through STAT3

scientific article

Iron Absorption

Iron Deficiency Anemia Associated with an Error of Iron Metabolism in Two Siblings: A Thirty Year Follow Up.

scientific article

Iron Metabolism

Iron Metabolism: Disorders

Iron and copper in mitochondrial diseases

scientific article published on March 2013

Iron homeostasis

scientific article published on January 2007

Iron homeostasis and erythropoiesis

scientific article published on January 2008

Iron homeostasis and inherited iron overload disorders: an overview

scientific article

Iron homeostasis: insights from genetics and animal models

scientific article published on 01 December 2000

Iron in skin of mice with three etiologies of systemic iron overload.

scientific article

Iron is essential for neuron development and memory function in mouse hippocampus

scientific journal article

Iron metabolism and absorption

Iron metabolism in mice with partial frataxin deficiency.

scientific article published in January 2003

Iron-dependent regulation of the divalent metal ion transporter

scientific article (publication date: 7 December 2001)

Late stage erythroid precursor production is impaired in mice with chronic inflammation

scientific article

Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

scientific article published on 7 October 2015

Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle

scientific article published on 04 October 2015

Metal transporters and disease

scientific article

Mining copper transport genes

scientific article

Mitogen-activated protein kinases enhance long-range activation by the beta-globin locus control region

scientific article

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

scientific article

Molecular Characterization and Localization of the HumanMAFGGene ⬇️

scientific article published on August 15, 1997

Molecular control of iron metabolism

scientific article

Molecular insights into mechanisms of iron transport

scientific article

Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter.

scientific article

Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice

scientific article

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

scientific article

Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis

scientific article

Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences

scientific article published on December 1994

Nramp2 Transports Ferrous Iron, and is Defective in mk Mice and b Rats • 800

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

scientific article published on February 1998

Pathophysiologic mechanisms of anemia of chronic disease

scientific article

Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence

scientific article published on 01 March 1981

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

scientific article (publication date: 17 February 2000)

Positive and negative elements regulate human interleukin 3 expression ⬇️

scientific article published on July 1, 1990

Probing the iron pool. Focus on “Detection of intracellular iron by its regulatory effect”

scientific article published on 01 December 2004

Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse

scientific article

Proinflammatory state, hepcidin, and anemia in older persons

scientific article

Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner

scientific article

Randomized trial of a physician-based intervention to increase the use of folic acid supplements among women.

scientific article published in April 2005

Regulation of iron absorption in Hfe mutant mice

scientific article published in August 2002

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

scientific article published in May 2003

Research in academic medical centers: two threats to sustainable support.

scientific article published in May 2015

Scara5 is a ferritin receptor mediating non-transferrin iron delivery

scientific journal article

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

scientific article

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

scientific journal article

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

article published in 2005

TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation

scientific article

The Maf transcription factors: regulators of differentiation

scientific article

The Molecular Basis of Iron Metabolism

The NF-E2 transcription factor

scientific article

The channel kinase, TRPM7, is required for early embryonic development

scientific article published on 27 December 2011

The function of heme-regulated eIF2alpha kinase in murine iron homeostasis and macrophage maturation

scientific journal article

The ins and outs of iron homeostasis

scientific article

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

scientific article

The iron transporter DMT1.

scientific article

The molecular defect in hypotransferrinemic mice

scientific article published on 01 August 2000

The molecular regulation of iron metabolism

scientific article published in January 2004

The other physician-scientist problem: Where have all the young girls gone?

scientific article published on 01 May 2002

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

scientific article published on March 2008

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice

scientific article

Transferrin

scientific article

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

scientific article

Transferrin is required for early T-cell differentiation

scientific article published on 01 August 2004

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

scientific article

Transferrin receptor 1 is differentially required in lymphocyte development.

scientific article published on 24 July 2003

Transferrin receptor is necessary for development of erythrocytes and the nervous system

scientific journal article

Understanding Heme Transport

scientific article published on 01 December 2005

Uroporphyria in Hfe mutant mice given 5-aminolevulinate: a new model of Fe-mediated porphyria cutanea tarda

scientific article

When Is a Heme Transporter Not a Heme Transporter? When It's a Folate Transporter

scientific article published on 01 January 2007

Women: diversity among leaders is there if you look

scientific article

p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes

scientific article

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

scientific article

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