Search filters

List of works by Robert Snoeck

(+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral properties

scientific article (publication date: 12 June 1992)

(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity

scientific article published in April 2001

(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication

scientific article

(±)-7-deazaaristeromycin lacking the hydroxymethyl substituent

scientific article published in 1993

2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.

scientific article published on 3 October 2009

2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections

scientific article published on September 2002

4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action

scientific article

4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus

scientific article

4-Benzyloxy-γ-Sultone Derivatives: Discovery of a Novel Family of Non-Nucleoside Inhibitors of Human Cytomegalovirus and Varicella Zoster Virus

5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication

scientific article (publication date: August 1991)

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity

scientific article published on November 2003

5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells

scientific article published on 23 May 2007

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity

scientific article

6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity

scientific article published in October 2004

9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo

scientific article

A European multi-centre External Quality Assessment (EQA) study on phenotypic and genotypic methods used for Herpes Simplex Virus (HSV) drug resistance testing.

scientific article published on 6 October 2017

A case of human orf in an immunocompromised patient treated successfully with cidofovir cream

scientific article

A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity

scientific article (publication date: 2013)

A rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frame

scientific article

Abatement of Cutaneous Kaposi's Sarcoma Associated with Cidofovir Treatment

article

Activities of acyclic nucleoside phosphonates against Orf virus in human and ovine cell monolayers and organotypic ovine raft cultures

scientific article published on December 2005

Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures

scientific article

Activities of different classes of acyclic nucleoside phosphonates against BK virus in primary human renal cells.

scientific article published on 22 February 2011

Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models ⬇️

scientific article

Activity and mechanism of action of HDVD, a novel pyrimidine nucleoside derivative with high levels of selectivity and potency against gammaherpesviruses

scientific article published on 23 January 2013

Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro.

scientific article

Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and camelpox viruses in cell monolayers and organotypic raft cultures

scientific article published in January 2007

Acyclic nucleoside phosphonates containing the amide bond

scientific article published on 26 October 2016

Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity

scientific article published on 22 June 2011

Acyclic/carbocyclic guanosine analogues as anti-herpesvirus agents.

scientific article

Acyclovir-resistant herpes simplex encephalitis in a patient treated with anti-tumor necrosis factor-α monoclonal antibodies

scientific article published on 31 October 2013

Adjuvant low-dose cidofovir therapy for BK polyomavirus interstitial nephritis in renal transplant recipients.

scientific article published in August 2005

Advances in the treatment of varicella-zoster virus infections.

scientific article published on January 2013

Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus

scientific article published on 14 March 2009

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

article

Amidate Prodrugs of Cyclic 9-()-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity

An epimer of 5'-noraristeromycin and its antiviral properties.

scientific article published on April 1994

Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes

scientific article

Anti-influenza virus activity and structure-activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains.

scientific article

Anti-varicella-zoster virus bicyclic nucleosides: replacement of furo by pyrro base reduces antiviral potency

scientific article published in September 2000

Antiadenovirus activities of several classes of nucleoside and nucleotide analogues

scientific article published on March 2005

Antiherpesvirus activities of two novel 4'-thiothymidine derivatives, KAY-2-41 and KAH-39-149, are dependent on viral and cellular thymidine kinases

scientific article published on 12 May 2014

Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells

scientific article

Antitumor Potential of Acyclic Nucleoside Phosphonates

scientific article published on 01 April 1999

Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives

scientific article published on 28 September 2019

Antivaccinia activities of acyclic nucleoside phosphonate derivatives in epithelial cells and organotypic cultures

scientific article published on November 2002

Antiviral Drug-Resistance Typing Reveals Compartmentalization and Dynamics of Acyclovir-Resistant Herpes Simplex Virus Type-2 (HSV-2) in a Case of Neonatal Herpes

scientific article published on 8 August 2013

Antiviral Potency of ST-246 on the Production of Enveloped Orthopoxviruses and Characterization of ST-246 Resistant Vaccinia, Cowpox and Camelpox Viruses

article

Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds

scientific article

Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV.

scientific article published in January 2007

Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs

scientific article

Antiviral activity of a novel compound P-4018 against different strains of herpes simplex virus in vitro and in vivo

scientific article published in 1997

Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique

scientific article (publication date: July 1991)

Antiviral activity of ganciclovir elaidic acid ester against herpesviruses

scientific article

Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds

scientific article published on 14 February 2007

Antiviral activity spectrum of phenoxazine nucleoside derivatives

scientific article published on 23 January 2019

Antiviral and Cytostatic Evaluation of 5-(1-Halo-2-sulfonylvinyl)- and 5-(2-Furyl)uracil Nucleosides.

scientific article published on 17 March 2017

Antiviral and cytostatic evaluation of the novel 6-acyclic chain substituted thymine derivatives

scientific article published on January 2005

Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo

scientific article published on July 2002

Antiviral effect of the nucleoside analogue cidofovir in the context of sexual transmission of a gammaherpesvirus in mice

scholarly article by Caroline Zeippen et al published 16 May 2018 in Journal of Antimicrobial Chemotherapy

Antiviral enantiomeric preference for 5'-noraristeromycin.

scientific article published on February 1994

Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines

scientific article published on January 2005

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

scientific article published on 18 April 2006

Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus.

scientific article published on 6 November 2015

Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity

scientific article published in May 2004

Bicyclic furo pyrimidine nucleosides with aryloxyphenyl and halophenyl substituted side chains as potent and selective varicella-zoster virus inhibitors

scientific article published in April 2001

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain.

scientific article

Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of terminal unsaturation in the side chain

scientific article

Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain

scientific article published on August 2005

Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): effect of terminal unsaturation in the side-chain

scientific article published in April 2001

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.

scientific article

Bicyclic nucleoside inhibitors of varicella-zoster virus: 5'-chloro and 3'-chloro derivatives

scientific article published in May 2003

Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives

scientific article published in May 2003

Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.

scientific article published on September 1998

CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor

scientific article published on October 2002

CRISPR/Cas9 Editing of the Polyomavirus Tumor Antigens Inhibits Merkel Cell Carcinoma Growth In Vitro

scientific article published on 28 August 2019

Camelpox virus

scientific article published on 16 September 2011

Carbocyclic 5'-nor "reverse" fleximers. Design, synthesis, and preliminary biological activity

scientific article published on July 2011

Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation

scientific article published on 8 September 2005

Characterization of Cowpox Virus (CPV) Mutants Arising under Pressure with Different Acyclic Nucleoside Phosphonates

scientific article published in 2009

Characterization of herpes simplex virus type 1 thymidine kinase mutants selected under a single round of high-dose brivudin

scientific article published on May 2005

Chemotherapy of varicella zoster virus infections.

scientific article published in August 1994

Cidofovir Activity against Poxvirus Infections ⬇️

scientific article published on December 22, 2010

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms

scientific article published on 16 June 2016

Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice

scientific article published on October 2006

Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage

scientific article

Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice

scientific article

Cidofovir, a new approach for the treatment of cervix intraepithelial neoplasia grade III (CIN III)

scientific article published on 01 February 2000

Cidofovir: clinical experience and future perspectives on an acyclic nucleoside phosphonate analog of cytosine in the treatment of refractory and premalignant HPV-associated anal lesions

scientific article published on June 2009

Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus

scientific article published on December 1991

Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus

scientific article published on April 1995

Comparative activity of various compounds against clinical strains of herpes simplex virus

scientific article published in February 1992

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

scientific article published on 9 January 2018

Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping

scientific article published on 11 August 2015

Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products

scientific article published on 19 January 2017

Cross-Metathesis Mediated Synthesis of New Acyclic Nucleoside Phosphonates

scientific article published on 01 January 2007

Current acquisitions in antiviral drugs (anti-HIV)

scientific article published on July 1, 1992

DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.

scientific article

Desferrioxamine enhances AIDS-associated Kaposi's sarcoma tumor development in a xenograft model

scientific article

Design, Synthesis and Biological Evaluation of Novel Acyclovir ProTides

scientific article published in 2008

Design, Synthesis and Evaluation of Novel Anti-VZV BCNAs

scientific article published in 2008

Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates

scientific article published on 17 November 2015

Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole-Thiourea Scaffold as Antituberculosis Agents

scientific article published on January 2016

Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides

scientific article

Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues

scientific article published on 6 May 2015

Design, synthesis and antiviral evaluation of novel acyclic phosphonate nucleotide analogs with triazolo[4,5-b]pyridine, imidazo[4,5-b]pyridine and imidazo[4,5-b]pyridin-2(3H)-one systems

scientific article published on 25 September 2019

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides

scientific article published on 27 May 2011

Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives

article

Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues

scientific article

Development of a Model for the Study of Antivirals Against Molluscum Contagiosum Virus (MCV)

scientific article published in 2008

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

scientific article

Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation

scholarly article by Hanane Kaoukabi et al published July 2018 in European Journal of Medicinal Chemistry

Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues

scientific article published on 18 February 2011

Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism.

scientific article

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

scientific article published on 29 September 2016

Drug targets in cytomegalovirus infection

scientific article published on April 2009

Dual anti-HSV and anti-HIV activity of the lantibiotic Labyrinthopeptin A1

article

Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient

scientific article

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice

scientific article published in April 1993

Emergence of cowpox: study of the virulence of clinical strains and evaluation of antivirals

scientific article

Emerging drugs for varicella-zoster virus infections ⬇️

scientific article published on June 24, 2011

Emimycin and its nucleoside derivatives: Synthesis and antiviral activity

scientific article published on 7 December 2017

Epithelial raft cultures for investigations of virus growth, pathogenesis and efficacy of antiviral agents.

scientific article published on 31 October 2009

Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity

scientific article published on 19 October 2007

Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells

scientific article published on 11 September 2013

Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.

scientific article published on 28 October 2010

Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs

scientific article published on 6 July 2017

Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs

scholarly article by Elisa Pileggi published in July 2018

Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics

scientific article published on 03 March 2016

Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products

scientific article published on 5 January 2017

Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents

scientific article

Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus

scientific article

From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.

scientific article published in April 2005

From β-Amino-γ-sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral Activities

article

Furano pyrimidines as novel potent and selective anti-VZV agents

scientific article

GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions.

scientific article published on 27 April 2009

Halophenyl furanopyrimidines as potent and selective anti-VZV agents

scientific article published in May 2003

Herpes simplex virus drug-resistance: new mutations and insights

scientific article published on December 2013

Herpesvirus infections in immunocompromised patients

scientific article

Heterogeneity and evolution of thymidine kinase and DNA polymerase mutants of herpes simplex virus type 1: implications for antiviral therapy

scientific article

Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates

scientific article published on 31 January 2018

Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain

scientific article

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma

scientific article

Identification of Bicyclic Sulfone Inhibitors of HHV-6 Targeting the HHV-6 U77 Helicase

scientific article published in 2011

Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor

scientific article

Identification of the Type of Cells Responsible for Transfer of Herpes Simplex Virus (HSV) and Vaccinia Virus (VACV) Infection to Epithelial Cells Grown in 3D

scientific article published in 2009

Imbalance in Production of Cytokines by Bone Marrow Stromal Cells following Cytomegalovirus Infection

article

Imidazothiadiazine dioxides: synthesis and antiviral activity

scientific article

In Vitro -Selected Drug-Resistant Varicella-Zoster Virus Mutants in the Thymidine Kinase and DNA Polymerase Genes Yield Novel Phenotype-Genotype Associations and Highlight Differences between Antiherpesvirus Drugs ⬇️

scientific article published on December 21, 2011

In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.

scientific article published on 13 December 2006

In vitro sensitivity of Kaposi's sarcoma cells to various chemotherapeutic agents including acyclic nucleoside phosphonates.

scientific article

In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine

scientific article

Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase

scientific article published on March 2004

Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus

scientific article published on April 2002

Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).

scientific article published on 24 March 2007

Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.

scientific article published on 13 September 2008

Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir

scientific article published on 23 March 2009

Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains

scientific article published on 9 April 2007

Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro

scientific article published in August 1990

Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia.

scientific article

Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine

scientific article published on 19 August 2008

Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient

scientific article published on 6 December 2004

Introduction to the Special Issue dedicated to Prof. Erik De Clercq for reaching the Professor Emeritus status at the Katholieke Universiteit Leuven

scientific article published in 2006

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

scientific article

Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

scientific article

Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice

scientific article

Is the Large T Antigen a Target for the Inhibition of SV40 Replication?

scientific article published in 2010

Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity

scientific article published on 28 July 2018

KAY-2-41, a novel nucleoside analogue inhibitor of orthopoxviruses in vitro and in vivo

scientific article published on 14 October 2013

KSHV targeted therapy: an update on inhibitors of viral lytic replication

scientific article

Kaposi's sarcoma, oncogenic viruses, and iron.

scientific article

Kaposi's sarcoma-associated herpesvirus: the role of lytic replication in targeted therapy

scientific article

Lignosulfonic acid exhibits broad-spectrum anti-HIV and anti-HSV activity and has potential for microbicidal applications

article

Local treatment of HPV-induced skin lesions by Cidofovir

scientific article

Lymphocyte-independent pathways underlie the pathogenesis of murine cytomegalovirus-associated secondary hemophagocytic lymphohistiocytosis.

scientific article published on 27 November 2017

Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis

scientific article published on 19 December 2017

Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs

scientific article published on 8 October 2008

Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with AIDS.

scientific article published in November 1993

Metabolic and pharmacological characteristics of the bicyclic nucleoside analogues (BCNAs) as highly selective inhibitors of varicella-zoster virus (VZV).

scientific article published in May 2003

Methods in Anti-HCMV Research

scientific article published on 01 January 2000

Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity

article

Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis

scientific article

Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient.

scientific article published on 10 June 2016

Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus.

scientific article

Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219.

scientific article published on May 2013

N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity

scientific article published on 26 March 2014

N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase.

scientific article published on 3 January 2013

New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation

scientific article published on March 2002

New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

scientific article published on 30 April 2022

New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

scientific article published on 22 July 2016

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents

scientific article

New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.

scientific article published on June 1996

New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.

scientific article published on September 1996

New prodrugs of Adefovir and Cidofovir

scientific article published on 22 April 2011

New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity

scientific article

New treatments for genital herpes

scientific article

New treatments for genital herpes

article

Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?

scientific article published on 07 October 2011

No apparent effect of cidofovir in epidermodysplasia verruciformis

scientific article published on 01 February 2000

Non-nucleoside structures retain full anti-HCMV potency of the dideoxy furanopyrimidine family.

scientific article

Nosocomial bacteremia caused by Bacillus species.

scientific article published in December 1988

Novel Carbocyclic Nucleosides Containing A Cyclobutyl Ring. Guanosine and Adenosine Analogues ⬇️

scientific article published on July 1, 1998

Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues

scientific article published on 01 August 1997

Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides

scientific article published on 06 November 2019

Novel Therapeutics for Epstein⁻Barr Virus

scientific article published on 12 March 2019

Novel [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2" -dioxide) derivatives with anti-HIV-1 and anti-human-cytomegalovirus activity.

scientific article published on February 2005

Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates

scientific article

Novel aryl substituted bicyclic furo nucleosides as extremely potent and selective anti-VZV agents

scientific article published in April 2001

Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity

scientific article

Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.

scientific article published on 10 August 2015

Novel inhibitors of human CMV.

scientific article published on February 2008

Novel isoxazolidine analogues of homonucleosides and homonucleotides

scientific article published on 02 November 2016

Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships

scientific article published in January 2007

Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides

scientific article

Novel sulfated polysaccharides: dissociation of anti-human immunodeficiency virus activity from antithrombin activity.

scientific article published on February 1990

Orf nodules and immunosuppression: a case report and review of therapeutics

scientific article

Organotypic epithelial raft cultures as a model for evaluating compounds against alphaherpesviruses

scientific article published on November 2005

Ovine skin organotypic cultures applied to the ex vivo study of orf virus infection

scientific article

Palladium-catalyzed synthesis of (E)-5-(2-acylvinyl)-2′-deoxyuridines and their antiviral and cytotoxic activities

scientific article published in 1995

Papillomavirus and treatment

scientific article published on 23 June 2006

Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro

scientific article (publication date: July 1991)

Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro

scientific article published in July 1996

Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss

scientific article published on 15 June 2019

Phase II double-blind, placebo-controlled study of the safety and efficacy of cidofovir topical gel for the treatment of patients with human papillomavirus infection

scientific article published on 26 July 2001

Phosphonoamidate prodrugs of C5-substituted pyrimidine acyclic nucleosides for antiviral therapy.

scientific article published on 25 April 2017

Phosphonylated 8-Azahypoxantines as Acyclic Nucleotide Analogs

Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker.

scientific article published on 16 October 2015

Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission.

scientific article published on December 1998

Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants.

scientific article

Polyomavirus infection in pediatric renal transplant recipients: evaluation using a quantitative real-time PCR technique

scientific article published in October 2004

Polysulfonates derived from metal thiolate complexes as inhibitors of HIV-1 and various other enveloped viruses in vitro.

scientific article published on May 2002

Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base

scientific article

Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423.

scientific article published on January 2004

Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents

scientific article

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus

scientific article published on 22 October 2007

Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis

article

Pridine Oxide Derivatives: Structure‐Activity Relationship for Inhibition of Human Immunodeficiency Virus and Cytomegalovirus Replication in Cell Culture

scientific article

ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents.

scientific article published on 15 March 2014

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

scientific article (publication date: August 1988)

Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir

scientific article

Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

scientific article published on 25 January 2016

Role of cidofovir in the treatment of DNA virus infections, other than CMV infections, in immunocompromised patients.

scientific article

S-Adenosyl-L-homocysteine Hydrolase Inhibitors as Anti-Viral Agents: 5′-Deoxyaristeromycin

article

ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping

scientific article published on 27 January 2015

Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation

scientific article published on 10 January 2018

Selection and Characterization of (S)-1-[3-Hydroxy-2-(Phosphonomethoxypropyl)-2,6-Diaminopurine [HPMPDAP] Resistant Camelpox Viruses

article

Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).

scientific article published on November 1990

Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anticytomegalovirus agents

scientific article published on 01 November 1991

Sequestration of human cytomegalovirus by human renal and mammary epithelial cells

scientific article

Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim.

scientific article published on 2 January 2012

Solvent-free synthesis of pyrimidine nucleoside-aminophosphonate hybrids and their biological activity evaluation

scientific article published on August 2010

Sonication-Assisted Synthesis of(E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs

Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting the D5R gene

scientific article

Specific targeting of the F13L protein by ST-246 affects orthopoxvirus production differently

scientific article

Spectrum of activity and mechanisms of resistance of various nucleoside derivatives against gammaherpesviruses

scientific article published on 29 September 2014

Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base

scientific article

Structure–Activity Relationship of a Novel Class of Aglycoristocetin Derivatives with Potent and Broad Activity Against Influenza Viruses

scientific article published in 2009

Study of camelpox virus pathogenesis in athymic nude mice

scientific article (publication date: 2011)

Successful kinase bypass with new acyclovir phosphoramidate prodrugs

scientific article published on 24 June 2008

Successful treatment of a squamous papilloma of the hypopharynx-esophagus by local injections of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.

scientific article published on February 1995

Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).

scientific article published in April 1994

Successful treatment of recurrent vulvar intraepithelial neoplasia resistant to interferon and isotretinoin with cidofovir.

scientific article published in June 2001

Successful use of intralesional and intravenous cidofovir in association with indole-3-carbinol in an 8-year-old girl with pulmonary papillomatosis

scientific article published in February 2005

Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate

article

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

scientific article

Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides

scientific article published on March 2005

Synthesis and Antiviral Activities of Some Novel Carbocyclic Nucleosides

Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines

Synthesis and Antiviral Activity of Various N4-Acyl Derivatives of Cidofovir and its 5-Azacytosine Counterpart, 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine

scientific article published in 2008

Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring

scientific article published in October 1999

Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).

scientific article published on 07 March 2017

Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides.

scientific article published on 8 February 2016

Synthesis and Biological Evaluation of 1,2-Disubstituted Carbonucleosides of 6-Substituted Purine and 8-Azapurine

scientific article published on 01 April 1999

Synthesis and Biological Evaluation of Acyclic Nucleotide Analogues of Bicyclic Pyrimidine Bases

scientific article published in 2009

Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues

scientific article published on 07 August 2019

Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors

article

Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof

scientific article published on 16 May 2013

Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine.

scientific article published in May 2004

Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives

scientific article published in March 2006

Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives

scientific article published on 02 February 2019

Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues

scientific article published on 21 March 2009

Synthesis and anti-herpes activity of 5-trifluorovinyl-2′-deoxyuridine

scientific article published in 1992

Synthesis and anti-herpetic activity of phosphoramidate ProTides

scientific article published on 18 April 2013

Synthesis and anti-varicella-zoster virus activity of some novel bicyclic nucleoside inhibitors: effect of enhanced aqueous solubility

scientific article

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

scientific article published on July 1993

Synthesis and antiviral activities of 3-aralkylthiomethylimidazo[1,2-b]pyridazine derivatives

scientific article published on July 2003

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety

scientific article

Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV.

scientific article published in September 2003

Synthesis and antiviral activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil against HIV-1.

scientific article

Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds

scientific article published on June 2004

Synthesis and antiviral activity of 3-substituted imidazo[1,2-a]pyridines

article

Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines

scientific article

Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.

scientific article published on March 1993

Synthesis and antiviral activity of 6-benzoyl-benzoxazolin-2-one and 6-benzoyl-benzothiazolin-2-one derivatives

scientific article

Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain

scientific article (publication date: 17 April 1992)

Synthesis and antiviral activity of new pyrazole and thiazole derivatives.

scientific article published on 5 April 2009

Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines

scientific article published on 6 December 2007

Synthesis and antiviral activity of three pyrazole analogues of distamycin A.

scientific article published on June 1994

Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives

scientific article published on 2 August 2007

Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core

scientific article

Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines.

scientific article published on 21 April 2012

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides

article

Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates.

scientific article

Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine

scientific article published on September 2001

Synthesis and antiviral evaluation of some 3'-fluoro bicyclic nucleoside analogues

scientific article published in January 2004

Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design

scientific article

Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl)uracil derivatives

article

Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives

scientific article published on January 2006

Synthesis and biological evaluation of N- and O-alkylated bicyclic furanopyrimidines as non-nucleosidic inhibitors of human cytomegalovirus.

scientific article published on January 2005

Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues

scientific article published on 12 March 2012

Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides

scientific article published on July 2005

Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base

Synthesis and biological properties of C-2 triazolylinosine derivatives

scientific article

Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides

scientific article published on 4 July 2013

Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates.

scientific article published on 26 October 2016

Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin

scientific article published on 17 September 2014

Synthesis of O2- and N3-(2-Phosphonomethoxy)ethyl Derivatives of 6-Phenyl- and 6-Pyridinyl-5-azacytosine

article

Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents

scientific article published on October 2010

Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation

scientific article published on 21 December 2010

Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities.

scientific article published on 6 May 2014

Synthesis of unusual bicyclic nucleosides bearing an unsaturated side-chain, as potential inhibitors of varicella-zoster virus (VZV).

scientific article published on May 2003

Synthesis, Anti-varicella-zoster virus and Anti-cytomegalovirus Activity of 4,5-Disubstituted 1,2,3-(1H)-Triazoles

Synthesis, Biological Evaluation, and Structure Analysis of a Series of New 1,5-Anhydrohexitol Nucleosides

article

Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids.

scientific article published on February 2005

Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures

scientific article published on 04 October 2016

Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide

scientific article published on 9 March 2009

Synthesis, antiviral, cytotoxic and cytostatic evaluation of N 1-(phosphonoalkyl)uracil derivatives

scientific article published on 01 March 2016

Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues.

scientific article

Systemic cidofovir in papillomatosis

scientific article

Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection.

scientific article published on March 2010

Tenofovir Activating Kinases May Impact the Outcome of HIV Treatment and Prevention

scientific article published on 3 August 2015

The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications

scientific article

The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication ⬇️

scientific article published on December 1, 1994

The anti-HIV drug tenofovir, a reverse transcriptase inhibitor, also targets the herpes simplex virus (HSV) DNA polymerase

scientific article published on 23 November 2017

The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine

scientific article

The journey towards elucidating the anti-HCMV activity of alkylated bicyclic furano pyrimidines.

scientific article published on January 2005

The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications

scientific article

The large tumor antigen: a "Swiss Army knife" protein possessing the functions required for the polyomavirus life cycle.

scientific article

The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.

scientific article published on January 2005

The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations

scientific article

The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations.

scientific article published on 15 September 2007

Therapy for herpesvirus infections

Therapy of poxvirus infections

article

Thienothiadiazine 2,2-dioxide acyclonucleosides: synthesis and antiviral activity

scientific article published in May 2000

Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra.

scientific article

Topical cidofovir (HPMPC) is an effective adjuvant to surgical treatment of anogenital condylomata acuminata

scientific article published in August 2003

Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication

scientific article

Topical treatment of CIN 2+ by cidofovir: results of a phase II, double-blind, prospective, placebo-controlled study.

scientific article published on 3 August 2009

Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides.

scientific article

Treatment of a bowenoid papulosis of the penis with local applications of cidofovir in a patient with acquired immunodeficiency syndrome

scientific article

Treatment of anogenital papillomavirus infections with an acyclic nucleoside phosphonate analogue

scientific article published in October 1995

Treatment of intraurethral condylomata acuminata with surgery and cidofovir instillations in two immunocompromised patients and review of the literature

article

Treatment of severe laryngeal papillomatosis with intralesional injections of cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine].

scientific article

Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.

scientific article published on September 1994

Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity

scientific article published in 2006

Use of polymerase chain reaction for diagnosis of disseminated adenovirus infection

scientific article

Utilisation des antiviraux pour les orthopoxviroses

scientific article published on 01 June 2004

Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity

scientific article published on 07 December 2018

Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity

scientific article published on 17 July 2018

Verrucous carcinoma of the esophagus. A case report

scientific article published in February 2005

Viral DNA Polymerase Inhibitors

Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis and biological evaluation of new acyclic nucleoside ProTides

scientific article

Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus

scientific article published on 01 January 2018

Paulina is supported by:

About Paulina

Help