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List of works by Sun Choi

2-(3-Fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists: structure activity relationships of the 2-oxy pyridine C-region.

scientific article

2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent transient receptor potential vanilloid 1 (TRPV1) antagonists: structure-activity relationships of 2-amino derivatives in the N-(6-trifluoromethylpyridin-3-ylmethyl) C-region

scientific article

2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists

scientific article published on 02 June 2014

2-Aryl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists

scientific article published on 02 June 2014

2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

scientific article published on 28 January 2016

4-Aminophenyl acetamides and propanamides as potent transient receptor potential vanilloid 1 (TRPV1) ligands

scientific article published on 25 July 2018

5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1 expression

scientific article published on 15 September 2015

6,6-Fused heterocyclic ureas as highly potent TRPV1 antagonists.

scientific article published on 5 January 2015

8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation

scientific article published on 19 April 2012

Adaptable Small Ligand of CYP1 Enzymes for Use in Understanding the Structural Features Determining Isoform Selectivity

scientific article published on 29 October 2018

Advances in Molecular Dynamics Simulations and Enhanced Sampling Methods for the Study of Protein Systems

scientific article published on 01 September 2020

Anti-angiogenic activity of thienopyridine derivative LCB03-0110 by targeting VEGFR-2 and JAK/STAT3 Signalling.

scientific article

Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands.

scientific article published on 6 November 2013

Balancing focused combinatorial libraries based on multiple GPCR ligands

scientific article

Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity.

scientific article published in January 2008

Communication over the network of binary switches regulates the activation of A2A adenosine receptor ⬇️

scientific article (publication date: February 2015)

Design, synthesis, and anticancer activity of C8-substituted-4'-thionucleosides as potential HSP90 inhibitors.

scientific article published on 20 May 2016

Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift

scientific article published on 01 January 2021

Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer's Agents by Structure-Based Design

scientific article published on 27 August 2019

Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template.

scientific article published on 7 June 2016

Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine.

scientific article

Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.

scientific article

Efficient synthesis of 2-substituted 2,3-dihydro-4-quinolones as potential intermediates for 2-substituted 1,2,3,4-tetrahydro-4-quinolone antitumor agents

scientific article published on 01 May 2006

Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

scientific article published on 06 August 2018

Expediting the Design, Discovery, and Development of Anticancer Drugs using Computational Approaches.

scientific article

Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.

scientific article published on 9 March 2018

GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory

scientific article published in 2024

Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases

scientific article

Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades.

scientific article

Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development

scientific article published on 4 February 2013

Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)

scientific article published on 01 April 2019

In Vivo Albumin Traps Photosensitizer Monomers from Self-Assembled Phthalocyanine Nanovesicles: A Facile and Switchable Theranostic Approach

scientific article published on 02 January 2019

In silico classification of adenosine receptor antagonists using Laplacian-modified naïve Bayesian, support vector machine, and recursive partitioning.

scientific article published on 27 March 2010

In silico prediction of multiple-category classification model for cytochrome P450 inhibitors and non-inhibitors using machine-learning method.

scientific article published in October 2017

Inhibitory effect of tartrate against phosphate-induced DJ-1 aggregation

scientific article published on 10 October 2017

Integrated Ligand and Structure-Based Investigation of Structural Requirements for Silent Information Regulator 1 (SIRT1) Activation

scientific article published on 01 January 2018

Link between allosteric signal transduction and functional dynamics in a multisubunit enzyme: S-adenosylhomocysteine hydrolase.

scientific article published on 15 November 2011

MLACP: machine-learning-based prediction of anticancer peptides.

scientific article published on 19 August 2017

Mapping the intramolecular signal transduction of G-protein coupled receptors

scientific article published on 22 November 2013

Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs

scientific article

Multiscale Molecular Modeling in G Protein-Coupled Receptor (GPCR)-Ligand Studies

scientific article published on 19 April 2020

N-4-t-Butylbenzyl 2-(4-methylsulfonylaminophenyl) propanamide TRPV1 antagonists: Structure-activity relationships in the A-region.

scientific article

N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation

scientific article published on 5 April 2017

Novel Oxidative Modifications in Redox-Active Cysteine Residues ⬇️

scientific article published on December 10, 2010

Polymodal Transient Receptor Potential Vanilloid Type 1 Nocisensor: Structure, Modulators, and Therapeutic Applications.

scientific article published on 4 January 2016

Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region

scientific article published on 31 January 2018

Promiscuous gating modifiers target the voltage sensor of K(v)7.2, TRPV1, and H(v)1 cation channels

scientific article published on 5 March 2014

Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.

scientific article published on 12 August 2017

Recent Advances in Structure-Based Drug Design Targeting Class A G Protein-Coupled Receptors Utilizing Crystal Structures and Computational Simulations

scientific article

Receptor activity and conformational analysis of 5'-halogenated resiniferatoxin analogs as TRPV1 ligands

scientific article

Role of computer-aided drug design in modern drug discovery.

scientific article published on 25 July 2015

Selectivity enhancement arising from interactions at the PI3K unique pocket.

scientific article

Stereoselective functionalization of the 1'-position of 4'-thionucleosides

scientific article published on 01 September 2006

Structural Origins for the Loss of Catalytic Activities of Bifunctional Human LTA4H Revealed through Molecular Dynamics Simulations ⬇️

scientific article published on July 25, 2012

Structural and Biochemical Characterization of the Curcumin-Reducing Activity of CurA from Vibrio vulnificus

scientific article published on 02 October 2018

Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17.

scientific article

Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies ⬇️

scientific article published on March 30, 2011

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

scientific article published on 09 October 2015

Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities

scientific article published on 05 June 2015

Structure-activity relationships and molecular modeling of the N-(3-pivaloyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl] thiourea template for TRPV1 antagonism.

scientific article published on 13 April 2012

Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists.

scientific article published on 05 February 2014

Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors.

scientific article published on 30 June 2016

TRPV1 antagonist with high analgesic efficacy: 2-Thio pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides

scientific article published on 13 August 2013

The carbonate analogues of 5'-halogenated resiniferatoxin as TRPV1 ligands.

scientific article

The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.

scientific article published on 6 August 2016

The effects of biasing torsional mutations in a conformational GA.

scientific article published in July 2006

Total Synthesis of Hoiamide A Using an Evans-Tishchenko Reaction as a Key Step

scientific article published on 05 July 2019

Total synthesis of the putative structure of the proposed Banyasin A.

scientific article

Transient receptor potential vanilloid type 1 antagonists: a patent review (2011 - 2014).

scientific article published on March 2015

Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling

scientific article published on 04 April 2019

Ultraslow Water-Mediated Transmembrane Interactions Regulate the Activation of A2A Adenosine Receptor. ⬇️

scientific article published on September 2016

Understanding G Protein-Coupled Receptor Allostery via Molecular Dynamics Simulations: Implications for Drug Discovery.

scientific article published in January 2018

t-Butyl pyridine and phenyl C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.

scientific article published on 6 March 2017

α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists.

scientific article published on 12 April 2015

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