List of works - Brian T. Fife

A link between PDL1 and T regulatory cells in fetomaternal tolerance

scientific article published on 01 October 2007

Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity

scientific article published on 31 July 2020

Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease

scientific article

CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors

scientific article published on February 2016

Chemokine Regulation of Immune-mediated Demyelinating Disease

scientific article published on 01 September 1999

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

scientific article published on August 2008

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides

scientific article

Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation

scientific article published on 24 May 2017

Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control

scientific article published on 26 June 2013

Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade

scientific article

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice

scientific article published on 11 October 2013

Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes.

scientific article

Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

scientific article published on 13 June 2016

Eradication of Established Tumors by Chemically Self-Assembled Nanoring Labeled T Cells.

scientific article published on 4 June 2018

Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice ⬇️

scientific article published on November 22, 2010

Fractionated radiotherapy combined with PD-1 pathway blockade promotes CD8 T cell-mediated tumor clearance for the treatment of advanced malignancies

scientific article published on February 2016

Immunoneutralization of chemokines for the prevention and treatment of central nervous system autoimmune disease

scientific article published on 01 April 2003

Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.

scientific article published on 25 August 2017

Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes

scientific article published on 06 May 2019

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

scientific article

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

scientific article

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

scientific article

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.

scientific article

Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues

scientific article published on 01 March 2019

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.

scientific article published on 8 January 2018

Isolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation

scientific article

Keystone Symposia: chemokines and chemokine receptors. 16-21st February 2001, Taos, NM, USA

scientific article published on 01 May 2001

Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.

scientific article published on 29 August 2017

Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

scientific article published on 07 September 2020

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance

scientific article published on 26 September 2019

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

scientific article published on 12 July 2007

Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection

scientific article published on January 2016

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset

scientific article published on 20 February 2018

PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes

scientific article published on January 2016

PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

scientific article published on 4 April 2013

Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity

scientific article

Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes

scientific article published on 19 July 2019

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

scientific article published on 13 June 2016

Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodynia

scientific article

Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells

scientific article published on 24 January 2019

Selective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis

scientific article published on 01 November 2001

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

scientific article

T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes

scientific article published on 5 December 2017

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.

scientific article published in February 2018

T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

scientific article

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity

scientific article

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2

scientific article published on 11 March 2019

Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia ⬇️

scientific article published on 01 May 2019

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

scientific article

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns

scientific article

Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis

scientific article published on 11 November 2004

Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance

scientific article published on 26 April 2019

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

scientific article

List of works by Brian T. Fife

A link between PDL1 and T regulatory cells in fetomaternal tolerance

Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity

Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease

CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors

Chemokine Regulation of Immune-mediated Demyelinating Disease

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides

Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation

Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control

Cutting edge: identification of autoreactive CD4+ and CD8+ T cell subsets resistant to PD-1 pathway blockade

Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice

Editorial: Fresh Ideas, Foundational Experiments: Immunology and Diabetes.

Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment

Eradication of Established Tumors by Chemically Self-Assembled Nanoring Labeled T Cells.

Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice ⬇️

Fractionated radiotherapy combined with PD-1 pathway blockade promotes CD8 T cell-mediated tumor clearance for the treatment of advanced malignancies

Immunoneutralization of chemokines for the prevention and treatment of central nervous system autoimmune disease

Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes.

Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.

Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.

Isolation of Infiltrating Leukocytes from Mouse Skin Using Enzymatic Digest and Gradient Separation

Keystone Symposia: chemokines and chemokine receptors. 16-21st February 2001, Taos, NM, USA

Landscape review of current HIV 'kick and kill' cure research - some kicking, not enough killing.

Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance

Mechanisms of PDL1-mediated regulation of autoimmune diabetes

Most microbe-specific naïve CD4⁺ T cells produce memory cells during infection

Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset

PD-1 pathway-mediated regulation of islet-specific CD4+ T cell subsets in autoimmune diabetes

PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

Programmed Death-1 Culls Peripheral Accumulation of High-Affinity Autoreactive CD4 T Cells to Protect against Autoimmunity

Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

Repeated hapten exposure induces persistent tactile sensitivity in mice modeling localized provoked vulvodynia

Reprogramming responsiveness to checkpoint blockade in dysfunctional CD8 T cells

Selective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.

T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction

T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity

TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2

Tetrahydrocannabinol Reduces Hapten-Driven Mast Cell Accumulation and Persistent Tactile Sensitivity in Mouse Model of Allergen-Provoked Localized Vulvodynia ⬇️

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns

Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis

Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice