List of works - Mats Ohlin

A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy

scientific article published on 25 September 2019

A carbohydrate binding module as a diversity-carrying scaffold.

scientific article published in March 2004

A central core structure in an antibody variable domain determines antigen specificity

scientific article

A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2.

scientific article

A dimerized single-chain variable fragment system for the assessment of neutralizing activity of phage display-selected antibody fragments specific for cytomegalovirus

scientific article

A focused antibody library for improved hapten recognition

scientific article published on 19 January 2006

A folded and immunogenic IgE-hyporeactive variant of the major allergen Phl p 1 produced in Escherichia coli

scientific article published on 9 June 2015

A microarray-based reaction rate analysis platform. Is there evidence of validity?

scientific article published on 10 July 2015

A new look at a poorly immunogenic neutralization epitope on cytomegalovirus glycoprotein B. Is there cause for antigen redesign?

scientific article published on 4 May 2014

A novel mammalian display system for the selection of protein-protein interactions by decoy receptor engagement

scientific article

A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia

scientific article published on 03 September 2018

A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli

scientific article published on May 1995

AFFIRM--a multiplexed immunoaffinity platform that combines recombinant antibody fragments and LC-SRM analysis

scientific article published on 25 November 2014

Acoustic microfluidic chip technology to facilitate automation of phage display selection.

scientific article

Advancing the global proteome survey platform by using an oriented single chain antibody fragment immobilization approach

scientific article published on 15 December 2015

Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules

scientific article

Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

scientific article

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths

scientific article published on 13 November 2017

Antibody evolution beyond Nature

scientific article (publication date: December 2002)

Antibody evolution from the centre to the periphery: applied to a human antibody fragment recognising the tumour-associated antigen mucin-1.

scientific article

Antibody-encoding repertoires of bone marrow and peripheral blood-a focus on IgE.

scientific article published on 09 August 2016

Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region

scientific article published on 01 March 2002

Antigen-binding sites dominate the surface properties of IgG antibodies

scientific article published on 01 August 1995

Antigenic domain 1 of human cytomegalovirus glycoprotein B induces a multitude of different antibodies which, when combined, results in incomplete virus neutralization

scientific article published in August 1999

Antigens for the selection of pan-variable number of tandem repeats motif-specific human antibodies against Mucin-1.

scientific article

Augmented Phl p 5-specific Th2 response after exposure of dendritic cells to allergen in complex with specific IgE compared to IgG1 and IgG4.

scientific article published on 26 June 2008

Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences

scientific article published on 01 March 2020

Binding characteristics determine the neutralizing potential of antibody fragments specific for antigenic domain 2 on glycoprotein B of human cytomegalovirus

scientific article published in January 2003

Bioinspired assemblies of plant cell wall polymers unravel the affinity properties of carbohydrate-binding modules

scientific article published on 20 July 2015

CD4+CD57+ T cells derived from peripheral blood do not support immunoglobulin production by B cells

scientific article published on 01 July 1995

Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions

scientific article

Chain shuffling to modify properties of recombinant immunoglobulins

scientific article

Characteristics of human antibody repertoires following active immune responses in vivo

scientific article

Characterization of human monoclonal antibodies directed against the pp65-kD matrix antigen of human cytomegalovirus

scientific article published in June 1991

Characterization of the substitution pattern of cellulose derivatives using carbohydrate-binding modules

scientific article published on 24 December 2014

Charges drive selection of specific antibodies by phage display

scientific article

Clonal evolution and stereotyped sequences of human IgE lineages in aeroallergen-specific immunotherapy

scientific article published in 2023

Clonal repertoire diversification of a neutralizing cytomegalovirus glycoprotein B-specific antibody results in variants with diverse anti-viral properties

scientific article

Complementarity-determining region (CDR) implantation: a theme of recombination

scientific article

Critical steps for computational inference of the 3'-end of novel alleles of immunoglobulin heavy chain variable genes - illustrated by an allele of IGHV3-7

scientific article published on 30 August 2018

Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase

scientific article

Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques.

scientific article

Data on haplotype-supported immunoglobulin germline gene inference

scientific article

Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains.

scientific article

Decomplexing biofluids using microchip based acoustophoresis

scientific article published in December 2008

Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes

scientific article published on 30 July 2019

Delineating the specificity of an IgE-encoding transcriptome

scientific article

Differential effects of glycoprotein B epitope-specific antibodies on human cytomegalovirus-induced cell-cell fusion.

scientific article published in July 2003

Diversity of immunoglobulin E-encoding transcripts in sinus mucosa of subjects diagnosed with non-allergic fungal eosinophilic sinusitis

scientific article published on 29 March 2011

Effect of cysteine substitutions on dimerization and interfragment linkage of human cytomegalovirus glycoprotein B (gp UL55)

scientific article published on 01 January 1998

Engineered xyloglucan specificity in a carbohydrate-binding module

scientific article published on 10 August 2006

Enhanced ELISA sensitivity using TCA for efficient coating of biologically active lipopolysaccharides or lipid A to the solid phase

scientific article published on 01 November 1994

Epstein-Barr virus-induced transformation of human B lymphocytes: the effect of L-leucyl-L-leucine methyl ester on inhibitory T cell populations

scientific article published on December 1992

Evaluation of novel control elements by construction of eukaryotic expression vectors

scientific article published on April 1997

Evolution of a carbohydrate binding module into a protein-specific binder

scientific article published on 20 January 2006

Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization

scientific article

Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework

scientific article

Exploring central and peripheral diversity in antibody evolution

scientific article

Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies

scientific article published on February 1993

Flow cytometric analysis of the stability of antibody production by human x human x mouse heterohybridoma subclones

scientific article published on March 1994

Functional consequences of insertions and deletions in the complementarity-determining regions of human antibodies

scientific article published on 16 September 2002

Generation and analyses of human synthetic antibody libraries and their application for protein microarrays

scientific article

Generation of diversity in a human anti-viral response

scientific article published on 01 September 1995

Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins

scientific article

Human MoAbs produced from normal, HIV-1-negative donors and specific for glycoprotein gp120 of the HIV-1 envelope

scientific article published in August 1992

Human antibody reactivity against the lower matrix protein (pp65) produced by cytomegalovirus

scientific article

Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis

scientific article published on 01 December 1992

Human monoclonal antibodies with different fine specificity for digoxin derivatives: cloning of heavy and light chain variable region sequences

scientific article published in September 1991

Humoral immunity targeting site I of antigenic domain 2 of glycoprotein B upon immunization with different cytomegalovirus candidate vaccines

scientific article published on 09 November 2007

Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus

scientific article

Immunoglobulin production induced by CD57+ GC-derived helper T cells in vitro requires addition of exogenous IL-2

scientific article published on 01 May 1996

In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.

scientific article

In vitro evolution of an antibody fragment population to find high-affinity hapten binders

scientific article

In vitro immunization of naive human B cells yields high affinity immunoglobulin G antibodies as illustrated by phage display

scientific article published on September 1996

In vitro molecular evolution of antibody genes mimicking receptor revision

scientific article

Inconclusive evidence for or against positive antigen selection in the shaping of human immunoglobulin E repertoires: a call for new approaches

scientific article published on 22 January 2013

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

article

Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity

scientific article published in March 1998

Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins.

scientific article

Kinetic analysis of recombinant antibody-antigen interactions: relation between structural domains and antigen binding

scientific article published in June 1992

Length of the antibody heavy chain complementarity determining region 3 as a specificity-determining factor

scientific article published in July 2004

Light chain shuffling of a high affinity antibody results in a drift in epitope recognition

scientific article

Low affinity, antibody binding of an Escherichia coli-derived component.

scientific article published on February 1996

Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor cells

scientific article published on 21 September 2009

Multiple independent IgE epitopes on the highly allergenic grass pollen allergen Phl p 5.

scientific article

Neutron crystallographic studies reveal hydrogen bond and water-mediated interactions between a carbohydrate-binding module and its bound carbohydrate ligand

scientific article

New approach to steroid separation based on a low affinity IgM antibody

scientific article published in May 1998

Non-germ-line encoded residues are critical for effective antibody recognition of a poorly immunogenic neutralization epitope on glycoprotein B of human cytomegalovirus

Novel antibody specificities targeting glycoprotein B of cytomegalovirus identified by molecular library technology

scientific article

Novel xylan-binding properties of an engineered family 4 carbohydrate-binding module

scientific article

OGRDB: a reference database of inferred immune receptor genes

scientific article published on 01 January 2020

Parallel antibody germline gene and haplotype analyses support the validity of immunoglobulin germline gene inference and discovery

scientific article published on 04 April 2017

Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy

scientific article published on 7 November 2015

Phl p 1-specific human monoclonal IgE and design of a hypoallergenic group 1 grass pollen allergen fragment

scientific article published on 12 June 2013

Poorly Expressed Alleles of Several Human Immunoglobulin Heavy Chain Variable Genes are Common in the Human Population

scientific article published on 24 February 2021

Production of human monoclonal antibodies in dialysis tubing

scientific article published on 01 June 1991

Protein expression profiling of formalin-fixed paraffin-embedded tissue using recombinant antibody microarrays

scientific article published on 09 October 2013

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

scientific article

Restricted variable region gene usage and possible rheumatoid factor relationship among human monoclonal antibodies specific for the AD-1 epitope on cytomegalovirus glycoprotein B.

scientific article published in September 1994

Selection of antibodies based on antibody kinetic binding properties.

scientific article

Selection of binders from phage displayed antibody libraries using the BIAcore biosensor

scientific article published on October 1996

Selection of phage displayed antibodies based on kinetic constants

scientific article published on 01 February 1996

Site-directed primary in vitro immunization: production of HIV-1 neutralizing human monoclonal antibodies from lymphocytes obtained from seronegative donors.

scientific article published on March 1994

Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules

scientific article

Structural domains involved in human cytomegalovirus glycoprotein B-mediated cell-cell fusion.

scientific article published on September 1996

Subtle sequence differences in a tumour-associated peptide epitope translate into major changes in antigenicity

scientific article published on 16 February 2005

Synthetic xylan-binding modules for mapping of pulp fibres and wood sections

scientific article

The crystal structure of XG-34, an evolved xyloglucan-specific carbohydrate-binding module

scientific article

The effect of leucyl-leucine methyl ester on proliferation and Ig secretion of EBV-transformed human B lymphocytes.

scientific article published in April 1989

The functional 3'-end of immunoglobulin heavy chain variable (IGHV) genes

scientific article published on 27 February 2018

The human IgE repertoire

scientific article

The human IgE-encoding transcriptome to assess antibody repertoires and repertoire evolution

scientific article

The immune diversity in a test tube--non-immunised antibody libraries and functional variability in defined protein scaffolds

scientific article

The number and affinity of productive IgE pairs determine allergen activation of mast cells

scientific article published on 4 May 2017

Thermostable carbohydrate-binding modules in affinity chromatography

scientific article

Three-dimensional structure of a human Fab with high affinity for tetanus toxoid

scientific article

Transiently binding antibody fragments against Lewis x and sialyl-Lewis x.

scientific article published on 24 March 2006

Uneven distribution of repetitive trinucleotide motifs in human immunoglobulin heavy variable genes

scientific article published on 01 March 2002

Versatile high resolution oligosaccharide microarrays for plant glycobiology and cell wall research

scientific article

List of works by Mats Ohlin

A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy

A carbohydrate binding module as a diversity-carrying scaffold.

A central core structure in an antibody variable domain determines antigen specificity

A common idiotype in IgE and its relation to recognition of the grass pollen allergen Phl p 2.

A dimerized single-chain variable fragment system for the assessment of neutralizing activity of phage display-selected antibody fragments specific for cytomegalovirus

A focused antibody library for improved hapten recognition

A folded and immunogenic IgE-hyporeactive variant of the major allergen Phl p 1 produced in Escherichia coli

A microarray-based reaction rate analysis platform. Is there evidence of validity?

A new look at a poorly immunogenic neutralization epitope on cytomegalovirus glycoprotein B. Is there cause for antigen redesign?

A novel mammalian display system for the selection of protein-protein interactions by decoy receptor engagement

A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia

A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli

AFFIRM--a multiplexed immunoaffinity platform that combines recombinant antibody fragments and LC-SRM analysis

Acoustic microfluidic chip technology to facilitate automation of phage display selection.

Advancing the global proteome survey platform by using an oriented single chain antibody fragment immobilization approach

Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules

Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths

Antibody evolution beyond Nature

Antibody evolution from the centre to the periphery: applied to a human antibody fragment recognising the tumour-associated antigen mucin-1.

Antibody-encoding repertoires of bone marrow and peripheral blood-a focus on IgE.

Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region

Antigen-binding sites dominate the surface properties of IgG antibodies

Antigenic domain 1 of human cytomegalovirus glycoprotein B induces a multitude of different antibodies which, when combined, results in incomplete virus neutralization

Antigens for the selection of pan-variable number of tandem repeats motif-specific human antibodies against Mucin-1.

Augmented Phl p 5-specific Th2 response after exposure of dendritic cells to allergen in complex with specific IgE compared to IgG1 and IgG4.

Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences

Binding characteristics determine the neutralizing potential of antibody fragments specific for antigenic domain 2 on glycoprotein B of human cytomegalovirus

Bioinspired assemblies of plant cell wall polymers unravel the affinity properties of carbohydrate-binding modules

CD4+CD57+ T cells derived from peripheral blood do not support immunoglobulin production by B cells

Carbohydrate binding module recognition of xyloglucan defined by polar contacts with branching xyloses and CH-Π interactions

Chain shuffling to modify properties of recombinant immunoglobulins

Characteristics of human antibody repertoires following active immune responses in vivo

Characterization of human monoclonal antibodies directed against the pp65-kD matrix antigen of human cytomegalovirus

Characterization of the substitution pattern of cellulose derivatives using carbohydrate-binding modules

Charges drive selection of specific antibodies by phage display

Clonal evolution and stereotyped sequences of human IgE lineages in aeroallergen-specific immunotherapy

Clonal repertoire diversification of a neutralizing cytomegalovirus glycoprotein B-specific antibody results in variants with diverse anti-viral properties

Complementarity-determining region (CDR) implantation: a theme of recombination

Critical steps for computational inference of the 3'-end of novel alleles of immunoglobulin heavy chain variable genes - illustrated by an allele of IGHV3-7

Crystallization, neutron data collection, initial structure refinement and analysis of a xyloglucan heptamer bound to an engineered carbohydrate-binding module from xylanase

Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques.

Data on haplotype-supported immunoglobulin germline gene inference

Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains.

Decomplexing biofluids using microchip based acoustophoresis

Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes

Delineating the specificity of an IgE-encoding transcriptome

Differential effects of glycoprotein B epitope-specific antibodies on human cytomegalovirus-induced cell-cell fusion.

Diversity of immunoglobulin E-encoding transcripts in sinus mucosa of subjects diagnosed with non-allergic fungal eosinophilic sinusitis

Effect of cysteine substitutions on dimerization and interfragment linkage of human cytomegalovirus glycoprotein B (gp UL55)

Engineered xyloglucan specificity in a carbohydrate-binding module

Enhanced ELISA sensitivity using TCA for efficient coating of biologically active lipopolysaccharides or lipid A to the solid phase

Epstein-Barr virus-induced transformation of human B lymphocytes: the effect of L-leucyl-L-leucine methyl ester on inhibitory T cell populations

Evaluation of novel control elements by construction of eukaryotic expression vectors

Evolution of a carbohydrate binding module into a protein-specific binder

Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization

Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework

Exploring central and peripheral diversity in antibody evolution

Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies

Flow cytometric analysis of the stability of antibody production by human x human x mouse heterohybridoma subclones

Functional consequences of insertions and deletions in the complementarity-determining regions of human antibodies

Generation and analyses of human synthetic antibody libraries and their application for protein microarrays

Generation of diversity in a human anti-viral response

Human IgE against the major allergen Bet v 1 - defining an epitope with limited cross-reactivity between different PR-10 family proteins

Human MoAbs produced from normal, HIV-1-negative donors and specific for glycoprotein gp120 of the HIV-1 envelope

Human antibody reactivity against the lower matrix protein (pp65) produced by cytomegalovirus

Human monoclonal antibodies against an epitope on the class 5c outer membrane protein common to many pathogenic strains of Neisseria meningitidis

Human monoclonal antibodies with different fine specificity for digoxin derivatives: cloning of heavy and light chain variable region sequences

Humoral immunity targeting site I of antigenic domain 2 of glycoprotein B upon immunization with different cytomegalovirus candidate vaccines

Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus

Immunoglobulin production induced by CD57+ GC-derived helper T cells in vitro requires addition of exogenous IL-2

In Vitro Evolution of Antibodies Inspired by In Vivo Evolution.

In vitro evolution of an antibody fragment population to find high-affinity hapten binders

In vitro immunization of naive human B cells yields high affinity immunoglobulin G antibodies as illustrated by phage display

In vitro molecular evolution of antibody genes mimicking receptor revision

Inconclusive evidence for or against positive antigen selection in the shaping of human immunoglobulin E repertoires: a call for new approaches

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming

Insertions and deletions in hypervariable loops of antibody heavy chains contribute to molecular diversity

Intra- and extracellular expression of an scFv antibody fragment in E. coli: effect of bacterial strains and pathway engineering using GroES/L chaperonins.