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List of works by Spencer Proctor

A novel complex of arginine-silicate improves micro- and macrovascular function and inhibits glomerular sclerosis in insulin-resistant JCR:LA-cp rats.

scientific article published in July 2005

A unique rodent model of cardiometabolic risk associated with the metabolic syndrome and polycystic ovary syndrome.

scientific article published on 21 May 2009

Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat.

scientific article published on 14 May 2015

Adiposity in Children and CVD Risk: ApoB48 Has a Stronger Association With Central Fat Than Classic Lipid Markers

scientific article

ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance

scientific article published on 13 March 2012

ApoB-lipoprotein remnant dyslipidemia and high-fat meal intolerance is associated with markers of cardiometabolic risk in youth with obesity

scientific article published on 04 November 2020

Apolipoprotein B48: a novel marker of metabolic risk in overweight children?

scientific article published in June 2007

Arterial intimal retention of pro-atherogenic lipoproteins in insulin deficient rabbits and rats

scientific article published on 01 April 2000

Arterial permeability and efflux of apolipoprotein B-containing lipoproteins assessed by in situ perfusion and three-dimensional quantitative confocal microscopy.

scientific article published on 2 September 2004

Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis.

scientific article

Arterial retention of remnant lipoproteins ex vivo is increased in insulin resistance because of increased arterial biglycan and production of cholesterol-rich atherogenic particles that can be improved by ezetimibe in the JCR:LA-cp rat

scientific article published on 25 October 2012

Beef Fat Enriched with Polyunsaturated Fatty Acid Biohydrogenation Products Improves Insulin Sensitivity Without Altering Dyslipidemia in Insulin Resistant JCR:LA-cp Rats

scientific article published on 12 April 2016

Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans

scientific article published on 28 April 2008

Brain inflammation is induced by co-morbidities and risk factors for stroke

scientific article

Cardiometabolic and reproductive benefits of early dietary energy restriction and voluntary exercise in an obese PCOS-prone rodent model

scientific article published on 17 July 2015

Cardiomyocyte Antihypertrophic Effect of Adipose Tissue Conditioned Medium from Rats and Its Abrogation by Obesity is Mediated by the Leptin to Adiponectin Ratio

scientific article published on 5 January 2016

Cardiovascular function in male and female JCR:LA-cp rats: effect of high-fat/high-sucrose diet

scientific article published on 13 January 2017

Choline deficiency impairs intestinal lipid metabolism in the lactating rat.

scientific article

Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet

scientific article

Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndrome

scientific article published on 31 January 2011

Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome.

scientific article published on June 2007

Current issues surrounding the definition of trans-fatty acids: implications for health, industry and food labels

scientific article published on 18 April 2013

Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia

scientific article published in December 2012

Delayed administration of interleukin-1 receptor antagonist reduces ischemic brain damage and inflammation in comorbid rats

scientific article

Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome

scientific article published on 15 November 2012

Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat.

scientific article published on 16 November 2009

Diets enriched in trans-11 vaccenic acid alleviate ectopic lipid accumulation in a rat model of NAFLD and metabolic syndrome

scientific article published on 18 March 2014

Differential expression of hypothalamic, metabolic and inflammatory genes in response to short-term calorie restriction in juvenile obese- and lean-prone JCR rats

scientific article

Down-regulation of hypothalamic pro-opiomelanocortin (POMC) expression after weaning is associated with hyperphagia-induced obesity in JCR rats overexpressing neuropeptide Y.

scientific article published on 7 October 2013

Effects of feeding flaxseed or sunflower-seed in high-forage diets on beef production, quality and fatty acid composition.

scientific article published on 12 April 2013

Effects of feeding steers extruded flaxseed on its own before hay or mixed with hay on animal performance, carcass quality, and meat and hamburger fatty acid composition

scientific article published on 19 April 2017

Effects of ruminant trans fatty acids on cardiovascular disease and cancer: a comprehensive review of epidemiological, clinical, and mechanistic studies.

scientific article

Elevated 20-HETE impairs coronary collateral growth in metabolic syndrome via endothelial dysfunction

scientific article published on 23 December 2016

Emerging pathways in the regulation of whole body cholesterol flux: therapeutic opportunities to target atherosclerosis?

scientific article

Evolution and obesity: resistance of obese-prone rats to a challenge of food restriction and wheel running.

scientific article published on 12 January 2010

Feeding history and obese-prone genotype increase survival of rats exposed to a challenge of food restriction and wheel running

scientific article published on 20 October 2011

Feeding long-chain n-3 polyunsaturated fatty acids to obese leptin receptor-deficient JCR:LA-cp rats modifies immune function and lipid-raft fatty acid composition

article

Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts.

scientific article

Human health benefits of vaccenic acid

scientific article published on October 2009

Hypersensitivity of prediabetic JCR:LA-cp rats to fine airborne combustion particle-induced direct and noradrenergic-mediated vascular contraction.

scientific article published on 11 January 2006

Hypolipidemic and cardioprotective benefits of a novel fireberry hawthorn fruit extract in the JCR:LA-cp rodent model of dyslipidemia and cardiac dysfunction.

scientific article published on 19 August 2016

Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet-induced metabolic syndrome

scientific article

Impaired ApoB-Lipoprotein and Triglyceride Metabolism in Obese Adolescents With Polycystic Ovary Syndrome

scientific article published on 20 December 2016

Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity

scientific article

Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome

scientific article published on 19 April 2006

Impaired postprandial metabolism of apolipoprotein B48-containing remnant particles in normolipidemic subjects with brittle type 1 diabetes

scientific article published on 01 February 2009

Improving beef hamburger quality and fatty acid profiles through dietary manipulation and exploitation of fat depot heterogeneity

scientific article published on 24 November 2014

Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat.

scientific article

Increased insulin sensitivity and reduced micro and macro vascular disease induced by 2-deoxy-D-glucose during metabolic syndrome in obese JCR: LA-cp rats.

scientific article

Increased risk of cardiovascular disease in Type 1 diabetes: arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans

scientific article published in January 2011

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption

scientific article published on 3 June 2010

Interrelationship of CB1R and OBR pathways in regulation of metabolic, neuroendocrine, and behavioral responses to food restriction and voluntary wheel running.

scientific article

Intestinal lipid transport and chylomicron production: possible links to exacerbated atherogenesis in a rodent model of the metabolic syndrome.

scientific article published on 15 July 2008

Intimal retention of cholesterol derived from apolipoprotein B100- and apolipoprotein B48-containing lipoproteins in carotid arteries of Watanabe heritable hyperlipidemic rabbits.

scientific article published on 3 July 2003

Irbesartan-mediated reduction of renal and cardiac damage in insulin resistant JCR : LA-cp rats.

scientific article published on 8 October 2009

Koch's postulates, microbial dysbiosis and inflammatory bowel disease.

scientific article published on 11 May 2016

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs

scientific article published on 5 March 2016

Metabolic effects of a novel silicate inositol complex of the nitric oxide precursor arginine in the obese insulin-resistant JCR:LA-cp rat.

scientific article published in October 2007

Methods to assess impaired post-prandial metabolism and the impact for early detection of cardiovascular disease risk.

scientific article published on 26 June 2009

Model of intestinal chylomicron over-production and ezetimibe treatment: impact on the retention of cholesterol in arterial vessels.

scientific article published on 14 May 2010

New Insights Into How the Intestine Can Regulate Lipid Homeostasis and Impact Vascular Disease: Frontiers for New Pharmaceutical Therapies to Lower Cardiovascular Disease Risk ⬇️

scientific article published on March 1, 2011

Novel Aspects of Nonfasting Lipemia in relation to Vascular Biology

scientific article published on 2 April 2012

Nutritional and Lipid Modulation of PCSK9: Effects on Cardiometabolic Risk Factors

scientific article published on 8 February 2017

Overeating by young obesity-prone and lean rats caused by tastes associated with low energy foods

scientific article published on 01 August 2007

Pair feeding-mediated changes in metabolism: stress response and pathophysiology in insulin-resistant, atherosclerosis-prone JCR:LA-cp rats.

scientific article published on 15 April 2008

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells

scientific article published on 10 January 2014

Postprandial lipemia as an early predictor of cardiovascular complications in childhood obesity.

scientific article published on 11 February 2009

Prior caloric restriction increases survival of prepubertal obese- and PCOS-prone rats exposed to a challenge of time-limited feeding and physical activity

scientific article published on 28 February 2013

Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial.

scientific article published on 27 September 2010

Retention of fluorescent-labelled chylomicron remnants within the intima of the arterial wall--evidence that plaque cholesterol may be derived from post-prandial lipoproteins.

scientific article published in June 1998

Sequential Feeding of Lipid Supplement Enriches Beef Adipose Tissues with 18:3n-3 Biohydrogenation Intermediates.

scientific article published on 25 May 2017

Simvastatin treatment upregulates intestinal lipid secretion pathways in a rodent model of the metabolic syndrome.

scientific article published on 13 November 2013

Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.

scientific article published in January 2007

The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator-activated receptor-α and -γ in a rodent model of dyslipidemia and the metabolic syndrome

article

Trans-11 Vaccenic Acid Reduces Hepatic Lipogenesis and Chylomicron Secretion in JCR:LA-cp Rats

scientific article published on 16 September 2009

Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR:LA-cp rats

scientific article published in November 2008

Trans-11 vaccenic acid improves insulin secretion in models of type 2 diabetes in vivo and in vitro

scientific article published on 20 January 2016

Types of oilseed and adipose tissue influence the composition and relationships of polyunsaturated fatty acid biohydrogenation products in steers fed a grass hay diet

scientific article published on 08 January 2014

Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases

scientific article

Vaccenic acid favourably alters immune function in obese JCR:LA-cp rats

scientific article published on 16 February 2009

Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat

scientific article published on 17 February 2016

Vaccenic and elaidic acid modify plasma and splenocyte membrane phospholipids and mitogen-stimulated cytokine production in obese insulin resistant JCR: LA-cp rats

scientific article published on 11 February 2010

miR-21 normalizes vascular smooth muscle proliferation and improves coronary collateral growth in metabolic syndrome

scientific article

miR-21-mediated decreased neutrophil apoptosis is a determinant of impaired coronary collateral growth in metabolic syndrome

scientific article published on 3 April 2015

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