List of works - Steven J. Brookes

A Fourth KLK4 Mutation Is Associated with Enamel Hypomineralisation and Structural Abnormalities

scientific article

A missense mutation in ITGB6 causes pitted hypomineralized amelogenesis imperfecta ⬇️

scientific article published on 06 December 2013

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta

scientific article

Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis

scientific article published on March 2013

Amelin extracellular processing and aggregation during rat incisor amelogenesis.

scientific article

Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair

scientific article

Amelogenesis Imperfecta; Genes, Proteins, and Pathways ⬇️

scientific article

Amelogenesis imperfecta caused by N-terminal enamelin point mutations in mice and men is driven by endoplasmic reticulum stress ⬇️

scientific article

An in vitro study of the use of photodynamic therapy for the treatment of natural oral plaque biofilms formed in vivo

scientific article published in May 1999

Biochemistry and molecular biology of amelogenin proteins of developing dental enamel.

scientific article published on January 1995

Cellular uptake and processing of enamel matrix derivative by human periodontal ligament fibroblasts

scientific article

Defects in the acid phosphatase ACPT cause recessive hypoplastic amelogenesis imperfecta ⬇️

scientific article published on 17 May 2017

Deletion of ameloblastin exon 6 is associated with amelogenesis imperfecta ⬇️

scientific article

Deletion of amelotin exons 3-6 is associated with amelogenesis imperfecta ⬇️

scientific article published on 12 July 2016

Determination of protein regions responsible for interactions of amelogenin with CD63 and LAMP1.

scientific article published on December 2007

EMD in periodontal regenerative surgery modulates cytokine profiles: A randomised controlled clinical trial ⬇️

scientific article published on 15 March 2016

Effect of experimental fluorosis on the surface topography of developing enamel crystals.

scientific article published in January 2001

Enamel Research: Priorities and Future Directions ⬇️

scientific article

Enamel defects reflect perinatal exposure to bisphenol A

scientific article published on 10 June 2013

Enamel matrix derivative enhances tissue formation around scaffolds used for tissue engineering of ligaments

scientific article

Enamel matrix derivative stimulates expression and secretion of resistin in mesenchymal cells

article

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate ⬇️

scientific article

Evidence for direct amelogenin-target cell interactions using dynamic force spectroscopy

scientific article published on May 2006

Evidence for regulation of amelogenin gene expression by 1,25-dihydroxyvitamin D3 in vivo

article

Fluoride reduces the expression of enamel proteins and cytokines in an ameloblast-derived cell line

scientific article published on 17 December 2010

Human osteoblastic cells discriminate between 20-kDa amelogenin isoforms

scientific article

Hydrostatic pressure modulates proteoglycan metabolism in chondrocytes seeded in agarose.

scientific article

Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta

scientific journal article

Is the 32-kDa fragment the functional enamelin unit in all species?

scientific article

Isolation and characterisation of an alternatively-spliced rat amelogenin cDNA: LRAP--a highly conserved, functional alternatively-spliced amelogenin?

scientific article published in November 1994

Mutations in C4orf26, encoding a peptide with in vitro hydroxyapatite crystal nucleation and growth activity, cause amelogenesis imperfecta

scientific article

Novel methodology for determining the effect of adsorbates on human enamel acid dissolution. ⬇️

scientific article

Plaque biofilms: the effect of chemical environment on natural human plaque biofilm architecture.

scientific article

Preparative SDS PAGE as an Alternative to His-Tag Purification of Recombinant Amelogenin ⬇️

scientific article published on 16 June 2017

Self-assembling Peptide Scaffolds Promote Enamel Remineralization

scientific article (publication date: May 2007)

Spatially related amelogenin interactions in developing rat enamel as revealed by molecular cross-linking studies

scientific article published in November 2000

Spectrum of PEX1 and PEX6 variants in Heimler syndrome ⬇️

scientific article published on 15 June 2016

Subfractions of enamel matrix derivative differentially influence cytokine secretion from human oral fibroblasts ⬇️

scientific article published on 19 March 2015

Surface chemistry of enamel apatite during maturation in relation to pH: implications for protein removal and crystal growth

scientific article published on 20 January 2005

The Importance of Serine Phosphorylation of Ameloblastin on Enamel Formation. ⬇️

scientific article published on 28 July 2016

The Unfolded Protein Response in Amelogenesis and Enamel Pathologies ⬇️

scientific article published on 8 September 2017

The chemical composition of tooth enamel in junctional epidermolysis bullosa

scientific article published in May 2000

The effect of fluoride on the developing tooth.

scientific article published on May 2004

The effect of glycosylaminoglycans on the mineralization of sheep periodontal ligament in vitro

scientific article published in January 1995

The potential use of enamel matrix derivative for in situ anterior cruciate ligament tissue engineering: a translational in vitro investigation

scientific article published in August 2007

The structure and composition of deciduous enamel affected by local hypoplastic autosomal dominant amelogenesis imperfecta resulting from an ENAM mutation.

scientific article

Tracking endogenous amelogenin and ameloblastin in vivo ⬇️

scientific article

Treatment of early caries lesions using biomimetic self-assembling peptides--a clinical safety trial ⬇️

scientific article

List of works by Steven J. Brookes

A Fourth KLK4 Mutation Is Associated with Enamel Hypomineralisation and Structural Abnormalities

A missense mutation in ITGB6 causes pitted hypomineralized amelogenesis imperfecta ⬇️

A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta

Adaptor protein complex 2-mediated, clathrin-dependent endocytosis, and related gene activities, are a prominent feature during maturation stage amelogenesis

Amelin extracellular processing and aggregation during rat incisor amelogenesis.

Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair

Amelogenesis Imperfecta; Genes, Proteins, and Pathways ⬇️

Amelogenesis imperfecta caused by N-terminal enamelin point mutations in mice and men is driven by endoplasmic reticulum stress ⬇️

An in vitro study of the use of photodynamic therapy for the treatment of natural oral plaque biofilms formed in vivo

Biochemistry and molecular biology of amelogenin proteins of developing dental enamel.

Cellular uptake and processing of enamel matrix derivative by human periodontal ligament fibroblasts

Defects in the acid phosphatase ACPT cause recessive hypoplastic amelogenesis imperfecta ⬇️

Deletion of ameloblastin exon 6 is associated with amelogenesis imperfecta ⬇️

Deletion of amelotin exons 3-6 is associated with amelogenesis imperfecta ⬇️

Determination of protein regions responsible for interactions of amelogenin with CD63 and LAMP1.

EMD in periodontal regenerative surgery modulates cytokine profiles: A randomised controlled clinical trial ⬇️

Effect of experimental fluorosis on the surface topography of developing enamel crystals.

Enamel Research: Priorities and Future Directions ⬇️

Enamel defects reflect perinatal exposure to bisphenol A

Enamel matrix derivative enhances tissue formation around scaffolds used for tissue engineering of ligaments

Enamel matrix derivative stimulates expression and secretion of resistin in mesenchymal cells

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate ⬇️

Evidence for direct amelogenin-target cell interactions using dynamic force spectroscopy

Evidence for regulation of amelogenin gene expression by 1,25-dihydroxyvitamin D3 in vivo

Fluoride reduces the expression of enamel proteins and cytokines in an ameloblast-derived cell line

Human osteoblastic cells discriminate between 20-kDa amelogenin isoforms

Hydrostatic pressure modulates proteoglycan metabolism in chondrocytes seeded in agarose.

Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta

Is the 32-kDa fragment the functional enamelin unit in all species?

Isolation and characterisation of an alternatively-spliced rat amelogenin cDNA: LRAP--a highly conserved, functional alternatively-spliced amelogenin?

Mutations in C4orf26, encoding a peptide with in vitro hydroxyapatite crystal nucleation and growth activity, cause amelogenesis imperfecta

Novel methodology for determining the effect of adsorbates on human enamel acid dissolution. ⬇️

Plaque biofilms: the effect of chemical environment on natural human plaque biofilm architecture.

Preparative SDS PAGE as an Alternative to His-Tag Purification of Recombinant Amelogenin ⬇️

Self-assembling Peptide Scaffolds Promote Enamel Remineralization

Spatially related amelogenin interactions in developing rat enamel as revealed by molecular cross-linking studies

Spectrum of PEX1 and PEX6 variants in Heimler syndrome ⬇️

Subfractions of enamel matrix derivative differentially influence cytokine secretion from human oral fibroblasts ⬇️

Surface chemistry of enamel apatite during maturation in relation to pH: implications for protein removal and crystal growth

The Importance of Serine Phosphorylation of Ameloblastin on Enamel Formation. ⬇️

The Unfolded Protein Response in Amelogenesis and Enamel Pathologies ⬇️

The chemical composition of tooth enamel in junctional epidermolysis bullosa

The effect of fluoride on the developing tooth.

The effect of glycosylaminoglycans on the mineralization of sheep periodontal ligament in vitro

The potential use of enamel matrix derivative for in situ anterior cruciate ligament tissue engineering: a translational in vitro investigation

The structure and composition of deciduous enamel affected by local hypoplastic autosomal dominant amelogenesis imperfecta resulting from an ENAM mutation.

Tracking endogenous amelogenin and ameloblastin in vivo ⬇️

Treatment of early caries lesions using biomimetic self-assembling peptides--a clinical safety trial ⬇️