List of works - Diogo Rodrigo Magalhaes Moreira

2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity

scientific article published on 07 July 2019

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation

scientific article published on 06 August 2014

A Model of Peptide Triazole Entry Inhibitor Binding to HIV-1 gp120 and the Mechanism of Bridging Sheet Disruption ⬇️

scientific article published on March 22, 2013

A Novel Hybrid of Chloroquine and Primaquine Linked by Gold(I): Multitarget and Multiphase Antiplasmodial Agent

scientific article published on 24 November 2020

A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90

scientific article published on 14 October 2019

A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells

scientific article published on 12 October 2018

Anti-inflammatory activity of SintMed65, an N-acylhydrazone derivative, in a mouse model of allergic airway inflammation

scientific article published on 12 July 2019

Antiparasitic evaluation of betulinic acid derivatives reveals effective and selective anti-Trypanosoma cruzi inhibitors

scientific article published on 11 April 2016

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

scientific article published on 6 June 2016

Approaches for the development of new anti-Trypanosoma cruzi agents.

scientific article published on March 2009

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

scientific article published on 08 August 2019

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

scientific article published in 2019

Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization

scientific article published on 11 June 2019

Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents

scientific article published on 21 July 2016

Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents

scientific article

Correlation between DNA/HSA-interactions and antimalarial activity of acridine derivatives: Proposing a possible mechanism of action

scientific article published on 19 October 2018

Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells.

scientific article

Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents

scientific article published on 24 January 2014

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

scientific article

Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities

scientific article published on 20 April 2015

Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi.

scientific article published on 20 July 2016

Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death

scientific article published on 16 February 2017

Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity ⬇️

scientific article

Evaluation of naphthoquinones identified the acetylated isolapachol as a potent and selective antiplasmodium agent.

scientific article published on 28 November 2014

Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles

scientific article published on 28 October 2013

Halogen atoms in the modern medicinal chemistry: hints for the drug design.

scientific article

In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi

scientific article published on 29 July 2015

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

scientific article published in 2019

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

scientific article published in 2019

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

scientific article published on 13 December 2013

Investigation of the antitrypanosomal effects of 2-formyl-8-hydroxyquinoline-derived hydrazones and their antimony(iii) and bismuth(iii) complexes

scientific article published in 2019

Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation

scientific article

New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.

scientific article published on 24 May 2016

Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death

scientific article

Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells.

scientific article published in November 2017

Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice

scientific article published on 31 August 2012

Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi

scientific article published on 11 January 2016

Physalins B and F, seco-steroids isolated from Physalis angulata L., strongly inhibit proliferation, ultrastructure and infectivity of Trypanosoma cruzi.

scientific article published on 4 September 2013

Recent insights on the medicinal chemistry of metal-based compounds: hints for the successful drug design.

scientific article published on January 2010

Ru(II) complexes containing uracil nucleobase analogs with cytotoxicity against tumor cells

scientific article published on 09 June 2019

Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.

scientific article

Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole

scientific article published on 02 January 2016

Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice

scientific article published on 07 December 2012

Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.

scientific article

Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy

scientific article published on 23 January 2017

Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities.

scientific article published on 21 July 2010

Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.

scientific article published on 29 September 2010

Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity

scientific article published on 25 February 2013

Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.

scientific article

Synthesis of 4'-(2-ferrocenyl)-2,2':6'2''-terpyridine: characterization and antiprotozoal activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes

scientific article published on 31 January 2014

Synthesis of piplartine analogs and preliminary findings on structure–antimicrobial activity relationship

Thiosemicarbazones as Aedes aegypti larvicidal

scientific article published on 28 May 2015

List of works by Diogo Rodrigo Magalhaes Moreira

2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation

A Model of Peptide Triazole Entry Inhibitor Binding to HIV-1 gp120 and the Mechanism of Bridging Sheet Disruption ⬇️

A Novel Hybrid of Chloroquine and Primaquine Linked by Gold(I): Multitarget and Multiphase Antiplasmodial Agent

A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90

A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells

Anti-inflammatory activity of SintMed65, an N-acylhydrazone derivative, in a mouse model of allergic airway inflammation

Antiparasitic evaluation of betulinic acid derivatives reveals effective and selective anti-Trypanosoma cruzi inhibitors

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

Approaches for the development of new anti-Trypanosoma cruzi agents.

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization

Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents

Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents

Correlation between DNA/HSA-interactions and antimalarial activity of acridine derivatives: Proposing a possible mechanism of action

Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells.

Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities

Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi.

Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death

Dimeric flavonoids from Arrabidaea brachypoda and assessment of their anti-Trypanosoma cruzi activity ⬇️

Evaluation of naphthoquinones identified the acetylated isolapachol as a potent and selective antiplasmodium agent.

Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles

Halogen atoms in the modern medicinal chemistry: hints for the drug design.

In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

Investigation of the antitrypanosomal effects of 2-formyl-8-hydroxyquinoline-derived hydrazones and their antimony(iii) and bismuth(iii) complexes

Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation

New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.

Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death

Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells.

Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice

Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi

Physalins B and F, seco-steroids isolated from Physalis angulata L., strongly inhibit proliferation, ultrastructure and infectivity of Trypanosoma cruzi.

Recent insights on the medicinal chemistry of metal-based compounds: hints for the successful drug design.

Ru(II) complexes containing uracil nucleobase analogs with cytotoxicity against tumor cells

Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.

Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole

Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice

Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.

Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy

Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities.

Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.

Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity

Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.

Synthesis of 4'-(2-ferrocenyl)-2,2':6'2''-terpyridine: characterization and antiprotozoal activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes

Synthesis of piplartine analogs and preliminary findings on structure–antimicrobial activity relationship

Thiosemicarbazones as Aedes aegypti larvicidal