List of works by Helen Tremlett

A longitudinal model for disease progression was developed and applied to multiple sclerosis

scientific article

A population-based study comparing multiple sclerosis clinic users and non-users in British Columbia, Canada.

scientific article published on 15 March 2016

A proposed methodology to estimate the cumulative life-time UVB exposure using geographic information systems: An application to multiple sclerosis.

scientific article

A review of safety-related pregnancy data surrounding the oral disease-modifying drugs for multiple sclerosis.

scientific article

Accurate classification of secondary progression in multiple sclerosis using a decision tree

scientific article published on 02 December 2020

Adherence and persistence to drug therapies for multiple sclerosis: A population-based study

scientific article published on 7 May 2016

Adherence to disease-modifying therapies for multiple sclerosis and subsequent hospitalizations

scientific article published on 03 April 2017

Adherence to laboratory monitoring among people taking oral drugs for multiple sclerosis: A Canadian population-based study

scientific article published on 06 March 2020

Adherence to the immunomodulatory drugs for multiple sclerosis: contrasting factors affect stopping drug and missing doses

scientific article published on June 2008

Adverse health behaviours are associated with depression and anxiety in multiple sclerosis: A prospective multisite study

scientific article published on 5 August 2015

Age Related Multiple Sclerosis Severity Score: Disability ranked by age.

scientific article

Age-related decreases in relapses among adults with relapsing-onset multiple sclerosis

scientific article published on 29 July 2019

Altered tryptophan metabolism is associated with pediatric multiple sclerosis risk and course

scientific article published on 27 September 2018

An 'epidemic' of multiple sclerosis and falling infection rates? Reflecting on comparisons made and the rising multiple sclerosis incidence in Bach's 2002 New England Journal of Medicine figure.

scientific article

Animal exposure over the life-course and risk of multiple sclerosis: A case-control study within two cohorts of US women

scientific article published on 15 November 2018

Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case-control study protocol for dimethyl fumarate-induced lymphopenia

scientific article published on 2 June 2017

Assessing the long-term effectiveness of interferon-beta and glatiramer acetate in multiple sclerosis: final 10-year results from the UK multiple sclerosis risk-sharing scheme

scientific article published on 21 September 2018

Assessment of cancer risk with β-interferon treatment for multiple sclerosis.

scientific article published on 4 March 2014

Association between beta-interferon exposure and hospital events in multiple sclerosis.

scientific article

Association between the use of selective serotonin reuptake inhibitors and multiple sclerosis disability progression

scientific article published on 23 May 2016

Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis

scientific article

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

scientific article

Asthma and multiple sclerosis: an inverse association in a case-control general practice population.

scientific article

Atlas of Multiple Sclerosis 2013: A growing global problem with widespread inequity

scientific article published in September 2014

Author response: Evaluating the safety of β-interferons in MS: A series of nested case-control studies

scientific article published in November 2017

Bayesian analysis of pair-matched case-control studies subject to outcome misclassification

scientific article published on 07 August 2017

Beta-interferon exposure and onset of secondary progressive multiple sclerosis

scientific article published on 06 April 2015

Birth outcomes in newborns fathered by men with multiple sclerosis exposed to disease-modifying drugs

scientific article

Birth outcomes of pregnancies fathered by men with multiple sclerosis.

scientific article published on 5 February 2014

Cancer risk in multiple sclerosis: findings from British Columbia, Canada

scientific article published on 21 June 2012

Cardiotoxicity and other adverse events associated with mitoxantrone treatment for MS.

scientific article

Characterising aggressive multiple sclerosis.

scientific article published on 6 June 2013

Characteristics associated with drug-induced liver injury from interferon beta in multiple sclerosis patients

scientific article published on 18 August 2014

Characteristics of a population-based multiple sclerosis cohort treated with disease-modifying drugs in a universal healthcare setting

scientific article published on 04 November 2020

Characteristics of multiple sclerosis in aboriginals living in British Columbia, Canada

scientific article published on March 2012

Children and adolescents adjustment to parental multiple sclerosis: a systematic review

scientific article

Children of chronically ill parents: Relationship between parental multiple sclerosis and childhood developmental health.

scientific article published on 18 December 2015

Children of chronically ill parents: the silence of research

scientific article published in September 2014

Chronic lung disease and multiple sclerosis: Incidence, prevalence, and temporal trends

scientific article published on 11 May 2016

Coming of age

scientific article published on 01 March 2005

Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis

scientific article published on 16 July 2018

Comorbidity increases the risk of relapse in multiple sclerosis: A prospective study

scientific article published on 8 November 2017

Comorbidity is associated with pain-related activity limitations in multiple sclerosis

scientific article published on 29 July 2015

Comparison of Statistical Approaches for Dealing With Immortal Time Bias in Drug Effectiveness Studies

scientific article published on 25 July 2016

Comparison of statistical approaches dealing with time-dependent confounding in drug effectiveness studies

scientific article

Concussion may not cause multiple sclerosis

scientific article published on 4 October 2017

Defining the natural history of MS: the need for complete data and rigorous definitions.

scientific article published on 13 August 2008

Determinants of neurological disease: Synthesis of systematic reviews.

scientific article

Determinants of non-adherence to disease-modifying therapies in multiple sclerosis: A cross-Canada prospective study

scientific article

Differences in the burden of psychiatric comorbidity in MS vs the general population

scientific article

Differing trends in the incidence of vascular comorbidity in MS and the general population

scientific article published on April 2016

Disability progression in aggressive multiple sclerosis

scientific article published on 20 June 2016

Disability progression in multiple sclerosis is slower than previously reported

scientific article published in January 2006

Disease-Modifying Therapies and Adherence in Multiple Sclerosis: Comparing Patient Self-Report with Pharmacy Records

scientific article

Disease-modifying drugs for multiple sclerosis and infection risk: a cohort study.

scientific article

Disease-modifying drugs for multiple sclerosis in pregnancy: A systematic review

article

Disease-modifying drugs for multiple sclerosis in pregnancy: a systematic review

scientific article

Disparities in management and outcomes of myocardial infarction in multiple sclerosis: A matched cohort study

scientific article published on 13 September 2019

Does the season or month of birth influence disease progression in multiple sclerosis?

scientific article

Drug exposure and the risk of multiple sclerosis: A systematic review.

scientific article published on 6 December 2017

Effect of adherence to the first-generation injectable immunomodulatory drugs on disability accumulation in multiple sclerosis: a longitudinal cohort study.

scientific article published on 29 September 2017

Effectiveness and cost-effectiveness of interferon beta and glatiramer acetate in the UK Multiple Sclerosis Risk Sharing Scheme at 6 years: a clinical cohort study with natural history comparator

scientific article published on April 2015

Effects of seasons on magnetic resonance imaging-measured disease activity in patients with multiple sclerosis

scientific article published on 01 September 2001

Epidemiology in multiple sclerosis has had its day: there are no more unanswered questions--no

scientific article

Examining the effects of comorbidities on disease-modifying therapy use in multiple sclerosis

scientific article published on 4 March 2016

Factors associated with delay to medical recognition in two Canadian multiple sclerosis cohorts

article

Factors associated with onset, relapses or progression in multiple sclerosis: A systematic review

scientific article published on April 2016

Fatigue and Comorbidities in Multiple Sclerosis

scientific article published on March 2016

Fatigue, sleep disorders, anaemia and pain in the multiple sclerosis prodrome

scientific article published on 06 April 2020

Five years before multiple sclerosis onset: Phenotyping the prodrome

scientific article published on 06 July 2018

Five-minute Apgar score as a marker for developmental vulnerability at 5 years of age.

scientific article published on 17 July 2015

From bugs to brains: The microbiome in neurological health

scientific article

General practitioners' prescribing data for multiple sclerosis patients indicates a link with asthma.

scientific article published in April 2000

Genetic variation associated with the occurrence and progression of neurological disorders.

scientific article published on 3 October 2016

Gut microbiota in early pediatric multiple sclerosis: a case-control study

scientific article

Health-care use before a first demyelinating event suggestive of a multiple sclerosis prodrome: a matched cohort study

scientific article published on 20 April 2017

Health-related quality of life in multiple sclerosis: Direct and indirect effects of comorbidity

scientific article published on 9 March 2016

Health-related quality of life in patients with longstanding 'benign multiple sclerosis'.

scientific article published on 7 October 2014

Hepatic injury, liver monitoring and the beta-interferons for multiple sclerosis

scientific article

High incidence and increasing prevalence of multiple sclerosis in British Columbia, Canada: findings from over two decades (1991-2010).

scientific article

High-dose frequency beta-interferons increase the risk of liver test abnormalities in multiple sclerosis: a longitudinal study.

scientific article published on 10 December 2010

Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis

scientific article published on August 2010

Hospital admissions and MS: temporal trends and patient characteristics.

scientific article published on November 2012

Impact of parental multiple sclerosis on early childhood development: A retrospective cohort study.

scientific article published on 12 January 2015

Incidence of Mood or Anxiety Disorders in Children of Parents with Multiple Sclerosis.

scientific article

Increased incidence and prevalence of psoriasis in multiple sclerosis

scientific article published on 20 February 2017

Infection-related health care utilization among people with and without multiple sclerosis.

scientific article

Informing Medication Discontinuation Decisions among Older Adults with Relapsing-Onset Multiple Sclerosis

scientific article published on 01 March 2020

Interferon beta and long-term disability in multiple sclerosis

scientific article published in May 2013

Interferon-β treatment and the natural history of relapsing-remitting multiple sclerosis

scientific article published on 01 January 2008

Interferons and multiple sclerosis: is it plausible that beta-IFN treatment could influence the risk of cancer among MS patients?

scientific article published in September 2009

Interrupted therapy: stopping and switching of the beta-interferons prescribed for MS.

scientific article

Investigation of heterogeneity in the association between interferon beta and disability progression in multiple sclerosis: an observational study

scientific article published on 18 December 2013

Is late-onset multiple sclerosis associated with a worse outcome?

scientific article published in September 2006

Labor induction and augmentation in women with multiple sclerosis.

scientific article

Liver and thyroid function and autoimmunity during interferon-beta 1b treatment for multiple sclerosis

scientific article published on 01 June 2002

Liver injury associated with the beta-interferons for MS: a comparison between the three products.

scientific article published on February 2004

Liver test abnormalities in multiple sclerosis: Findings from placebo-treated patients

scientific article published on 01 October 2006

Longitudinal follow-up of "benign" multiple sclerosis at 20 years

scientific article published on 01 February 2007

Malignant melanoma in a multiple sclerosis patient with persistent neutralizing antibodies to interferon-beta

scientific article published on 01 January 2008

Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review.

scientific article

Marginal structural Cox models for estimating the association between β-interferon exposure and disease progression in a multiple sclerosis cohort

scientific article

Mental comorbidity and multiple sclerosis: validating administrative data to support population-based surveillance

scientific article

Modelling disease progression in relapsing-remitting onset multiple sclerosis using multilevel models applied to longitudinal data from two natural history cohorts and one treated cohort

scientific article

Monthly ambient sunlight, infections and relapse rates in multiple sclerosis

scientific article published on 30 October 2008

Multiple sclerosis and pregnancy: What should we be telling our patients?

scientific article published on 18 November 2009

Multiple sclerosis in men: management considerations.

scientific article published on 02 January 2016

Multiple sclerosis in older adults: the clinical profile and impact of interferon Beta treatment

scientific article published on April 2015

Natural history comparisons of primary and secondary progressive multiple sclerosis reveals differences and similarities

scientific article published on 18 March 2009

Natural history of secondary-progressive multiple sclerosis

scientific article published on 21 January 2008

Natural, innate improvements in multiple sclerosis disability

scientific article published on 26 June 2012

Neonatal and delivery outcomes in women with multiple sclerosis

scientific article published on 27 June 2011

New perspectives in the natural history of multiple sclerosis

scientific article published on June 2010

Nonprescription medicine use in a multiple sclerosis clinic population.

scientific article published in July 2000

Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: associations with disease course and progression.

scientific article published on 7 September 2012

Oral versus intravenous corticosteroids in acute relapses of multiple sclerosis

Perinatal outcomes in women with multiple sclerosis exposed to disease-modifying drugs.

scientific article

Peripartum depression in parents with multiple sclerosis and psychiatric disorders in children

scientific article published on 22 February 2016

Physical comorbidities increase the risk of psychiatric comorbidity in multiple sclerosis

scientific article published on 29 June 2016

Predicting risk of secondary progression in multiple sclerosis: A nomogram

scientific article published on 18 June 2018

Prevalence and incidence of ischemic heart disease in multiple sclerosis: A population-based validation study

scientific article

Primary and secondary progressive MS have a similar age at onset of progression - NO.

scientific article published in April 2017

Prodrome in relapsing-remitting and primary progressive multiple sclerosis

scientific article published on 03 February 2019

Progressive lipoatrophy after cessation of glatiramer acetate injections: a case report

scientific article

Randomized multicenter trial of natalizumab in acute MS relapses: Clinical and MRI effects

scientific article published on 01 January 2005

Relapses in multiple sclerosis are age- and time-dependent

scientific article published on 05 June 2008

Relative mortality and survival in multiple sclerosis: findings from British Columbia, Canada

scientific article published on 23 August 2011

Reply to letter to the editor

scientific article published on 20 June 2019

Rising prevalence of vascular comorbidities in multiple sclerosis: validation of administrative definitions for diabetes, hypertension, and hyperlipidemia

scientific article

Risk factors associated with the onset of relapsing-remitting and primary progressive multiple sclerosis: a systematic review

scientific article

Safety of disease-modifying drugs for multiple sclerosis in pregnancy: current challenges and future considerations for effective pharmacovigilance.

scientific article published on March 2013

Serum proteomics in multiple sclerosis disease progression.

scientific article published on 6 March 2015

Sex differences in comorbidity at diagnosis of multiple sclerosis: A population-based study

scientific article published on 9 March 2016

Short-term laboratory and related safety outcomes for the multiple sclerosis oral disease-modifying therapies: an observational study

scientific article published on 19 December 2020

Sun exposure over the life course and associations with multiple sclerosis.

scientific article published on 7 March 2018

Suspected autoimmune hepatitis and primary biliary cirrhosis unmasked by interferon-beta in a multiple sclerosis patient.

scientific article

Symptomatic liver injury (hepatotoxicity) associated with administration of complementary and alternative products (Ayurveda-AP-Mag Capsules®) in a beta-interferon-treated multiple sclerosis patient

scientific article published on 01 July 2011

THE AUTHORS REPLY.

scientific article published on 16 November 2016

Temporal trends of disability progression in multiple sclerosis: findings from British Columbia, Canada (1975-2009).

scientific article published on 27 September 2011

Ten years of adverse drug reaction reports for the multiple sclerosis immunomodulatory therapies: a Canadian perspective

article

The gut microbiome in human neurological disease: A review

scientific article

The incidence and prevalence of fibromyalgia are higher in multiple sclerosis than the general population: A population-based study

scientific article

The incidence and prevalence of thyroid disease do not differ in the multiple sclerosis and general populations: a validation study using administrative data.

scientific article

The multiple sclerosis prodrome: Emerging evidence, challenges, and opportunities

scientific article published on 31 March 2020

The natural history of primary progressive MS in British Columbia, Canada

scientific article published in December 2005

The natural history of primary progressive multiple sclerosis.

scientific article

The natural history of secondary progressive multiple sclerosis

scientific article published on 16 July 2010

The potential role of pharmacogenomics in the prevention of serious adverse drug reactions in multiple sclerosis.

scientific article published on 10 January 2013

The psychosocial and cognitive impact of longstanding 'benign' multiple sclerosis

scientific article published on 15 June 2011

The reporting of observational studies of drug effectiveness and safety: recommendations to extend existing guidelines

scientific article published on 10 November 2020

The risks for falls and fractures in multiple sclerosis

scientific article published on 16 May 2012

The systematic search for risk factors in multiple sclerosis.

scientific article published on 04 February 2015

The utility of administrative data for surveillance of comorbidity in multiple sclerosis: a validation study

scientific article

Timing of birth and disease progression in multiple sclerosis

scientific article published on 23 June 2008

What went wrong in the natalizumab trials Comment?

scientific article published in The Lancet

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