List of works - Barbara Monti

3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease

scientific article published on 14 July 2015

Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death

scientific journal article

Alterations of markers related to synaptic function in aging rat brain, in normal conditions or under conditions of long-term dietary manipulation

scientific article published in June 2004

Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection

scientific article

Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum.

scientific article published in September 2000

Brain nitric oxide and its dual role in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches

scientific article

CRY1 Variations Impacts on the Depressive Relapse Rate in a Sample of Bipolar Patients

scientific article

Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation.

scientific article

Characterization of DNA methylation as a function of biological complexity via dinucleotide inter-distances ⬇️

scientific article published in March 2016

Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity

scientific article published on February 2009

Chronic valproic acid administration impairs contextual memory and dysregulates hippocampal GSK-3β in rats.

scientific article published on 6 March 2013

Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity

scientific journal article

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

scientific article published on 11 September 2019

Developmental effects of in vivo and in vitro inhibition of nitric oxide synthase in neurons

scientific article

Differential toxicity of protease inhibitors in cultures of cerebellar granule neurons

scientific article published in October 1998

Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice.

scientific article published on April 2005

Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.

scientific article

Dysregulation of memory-related proteins in the hippocampus of aged rats and their relation with cognitive impairment

scientific article published in January 2005

Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.

scientific article published on 2 March 2017

Genetic variations within metalloproteinases impact on the prophylaxis of depressive phases in bipolar patients

scientific article

Histone post-translational modifications in Huntington's and Parkinson's diseases.

scientific article published on January 2013

Histone post-translational modifications to target memory-related diseases

scientific article published on January 2013

In vitro and in vivo toxicity of type 2 ribosome-inactivating proteins lanceolin and stenodactylin on glial and neuronal cells

scientific article published on 2 February 2007

Memory-enhancing drugs: a molecular perspective

scientific article published on June 2009

Microglia and neuroprotection: from in vitro studies to therapeutic applications

scientific article published on 04 July 2010

Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects

scientific article

Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors

scientific article published on 11 December 2014

NMDA receptor-dependent CREB activation in survival of cerebellar granule cells during in vivo and in vitro development

scientific article published in October 2002

Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.

scientific article published in August 2015

Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2.

scientific article

Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids

scientific article published on 23 December 2014

Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.

scientific article

Regional alterations of the NO/NOS system in the aging brain: a biochemical, histochemical and immunochemical study in the rat.

scientific article

Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged rats and effect of dietary restriction

scientific article

Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear

scientific article published in February 2006

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.

scientific article published on 26 December 2016

The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon

scientific article

The electron transport system of the halophilic purple nonsulfur bacterium Rhodospirillum salinarum. 1. A functional and thermodynamic analysis of the respiratory chain in aerobically and photosynthetically grown cells.

scientific article published in October 1997

The transcription factor CCAAT enhancer-binding protein β protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms

scientific article published on 6 November 2013

Topography of neurochemical alterations in the CNS of aged rats

scientific article published in February 2001

Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

scientific article published on 21 July 2009

Zinc supplementation in rats impairs hippocampal-dependent memory consolidation and dampens post-traumatic recollection of stressful event

scientific article

List of works by Barbara Monti

3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease

Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death

Alterations of markers related to synaptic function in aging rat brain, in normal conditions or under conditions of long-term dietary manipulation

Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection

Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum.

Brain nitric oxide and its dual role in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches

CRY1 Variations Impacts on the Depressive Relapse Rate in a Sample of Bipolar Patients

Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation.

Characterization of DNA methylation as a function of biological complexity via dinucleotide inter-distances ⬇️

Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity

Chronic valproic acid administration impairs contextual memory and dysregulates hippocampal GSK-3β in rats.

Copper-zinc superoxide dismutase (SOD1) is released by microglial cells and confers neuroprotection against 6-OHDA neurotoxicity

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

Developmental effects of in vivo and in vitro inhibition of nitric oxide synthase in neurons

Differential toxicity of protease inhibitors in cultures of cerebellar granule neurons

Disease-related regressive alterations of forebrain cholinergic system in SOD1 mutant transgenic mice.

Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.

Dysregulation of memory-related proteins in the hippocampus of aged rats and their relation with cognitive impairment

Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.

Genetic variations within metalloproteinases impact on the prophylaxis of depressive phases in bipolar patients

Histone post-translational modifications in Huntington's and Parkinson's diseases.

Histone post-translational modifications to target memory-related diseases

In vitro and in vivo toxicity of type 2 ribosome-inactivating proteins lanceolin and stenodactylin on glial and neuronal cells

Memory-enhancing drugs: a molecular perspective

Microglia and neuroprotection: from in vitro studies to therapeutic applications

Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects

Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors

NMDA receptor-dependent CREB activation in survival of cerebellar granule cells during in vivo and in vitro development

Neuronal Regulation of Neuroprotective Microglial Apolipoprotein E Secretion in Rat In Vitro Models of Brain Pathophysiology.

Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2.

Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids

Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.

Regional alterations of the NO/NOS system in the aging brain: a biochemical, histochemical and immunochemical study in the rat.

Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged rats and effect of dietary restriction

Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.

The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon

The electron transport system of the halophilic purple nonsulfur bacterium Rhodospirillum salinarum. 1. A functional and thermodynamic analysis of the respiratory chain in aerobically and photosynthetically grown cells.

The transcription factor CCAAT enhancer-binding protein β protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms

Topography of neurochemical alterations in the CNS of aged rats

Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

Zinc supplementation in rats impairs hippocampal-dependent memory consolidation and dampens post-traumatic recollection of stressful event