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List of works by Diego De Stefani

A High-Throughput Screening Identifies MICU1 Targeting Compounds

scientific article published on 01 February 2020

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

scientific article

Breast Tissue Engineering: Decellularized Scaffolds Derived from Porcine Mammary Glands.

scientific article published in October 2015

Ca(2+) transfer from the ER to mitochondria: when, how and why

scientific article

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

scientific article

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy

scientific article published on 9 October 2017

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether

scientific article published on 19 September 2016

DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.

scientific article published on 12 June 2019

Enjoy the Trip: Calcium in Mitochondria Back and Forth

scientific article published on 4 May 2016

Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production.

scientific article published on 14 December 2013

Identification of an ATP-sensitive potassium channel in mitochondria

scientific article published on 21 August 2019

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux.

scientific article published on 17 November 2017

Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans

scientific article published on 01 October 2018

Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference.

scientific article published on 19 September 2018

Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization

scientific article published on 26 June 2008

Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling

scientific article

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB.

scientific article published on March 2015

MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics

scientific article published on 01 June 2019

MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity

scientific article

MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake.

scientific article published on 3 May 2018

Measuring baseline Ca(2+) levels in subcellular compartments using genetically engineered fluorescent indicators

scientific article published on January 2014

Mitochondria as sensors and regulators of calcium signalling

scientific article published on August 2012

Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes

scientific article

Mitochondrial Calcium Handling in Physiology and Disease

scientific article published in January 2017

Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism.

scientific article published on 25 June 2018

Molecular control of mitochondrial calcium uptake

scientific article published on 30 April 2014

Overexpression of Mitochondrial Calcium Uniporter Causes Neuronal Death

scientific article published on 16 October 2019

Reduced mitochondrial Ca(2+) transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase.

scientific article

Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria?

scientific article published on 13 March 2017

Respiratory dysfunction by AFG3L2 deficiency causes decreased mitochondrial calcium uptake via organellar network fragmentation

scientific article

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

scientific article published on 21 April 2009

Structure and function of the mitochondrial calcium uniporter complex

scientific article

Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca2+ handling

scientific article published on 11 July 2018

The MCU complex in cell death

scientific article published on 25 August 2017

The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria

scientific journal article

The mitochondrial Ca(2+) uniporter

scientific article published on 04 June 2012

The mitochondrial calcium uniporter (MCU): molecular identity and physiological roles

scientific article published on 11 February 2013

The mitochondrial calcium uniporter controls skeletal muscle trophism in vivo

scientific article

The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit

scientific journal article

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria.

scientific article published on July 2011