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List of works by Hans R. Widlund

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis

scientific article published on 31 August 2016

A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression

scientific article

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

scientific article

A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes

scientific article (publication date: 14 November 2003)

ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.

scientific article published on February 2017

An oncogenic role for ETV1 in melanoma

scientific article

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

scientific article published in February 2005

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

scientific article

CXCR4 pathway associated with family history of melanoma

scientific article

DNA sequence-dependent contributions of core histone tails to nucleosome stability: differential effects of acetylation and proteolytic tail removal

scientific article published on 01 April 2000

Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.

scientific article

ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas

scientific article published on 8 June 2017

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

scientific article published on 3 December 2003

Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF.

scientific article

IL1α antagonizes IL1β and promotes adaptive immune rejection of malignant tumors

scientific article published on 11 March 2020

Identification and characterization of genomic nucleosome-positioning sequences

scientific article published on 01 April 1997

Imatinib targeting of KIT-mutant oncoprotein in melanoma.

scientific article

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

scientific article (publication date: 7 July 2005)

MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin γ2 expression in oral dysplasia and squamous cell carcinoma.

scientific article

MC1R is a potent regulator of PTEN after UV exposure in melanocytes

scientific article published on August 2013

Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential

scientific article published on 10 March 2015

Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival.

scientific article

Molecular pathways: BRAF induces bioenergetic adaptation by attenuating oxidative phosphorylation

scientific article

Nucleosome structural features and intrinsic properties of the TATAAACGCC repeat sequence

scientific article published on 01 November 1999

Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF ⬇️

scientific article published on March 7, 2013

Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.

scientific article

PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors.

scientific article

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.

scientific article published on 14 February 2013

PIK3CA mutant tumors depend on oxoglutarate dehydrogenase

scientific article published on 10 April 2017

Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage

scientific article published on 27 June 2008

Potent p53-independent tumor suppressor activity of ARF in melanoma-genesis

scientific article published on 01 October 2007

RSK activation of translation factor eIF4B drives abnormal increases of laminin γ2 and MYC protein during neoplastic progression to squamous cell carcinoma

scientific article

Sequence motifs and free energies of selected natural and non-natural nucleosome positioning DNA sequences.

scientific article published on April 1999

Small interfering RNA.

scientific article published in December 2013

TGGA repeats impair nucleosome formation.

scientific article published in August 1998

Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma

scientific article (publication date: 15 January 2004)

Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation.

scientific article published on 05 December 2016

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