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List of works by Simon D. Brandt

'APAAN in the neck' - A reflection on some novel impurities found in seized materials containing amphetamine in Ireland during routine forensic analysis.

scientific article published on 23 March 2017

1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances

scientific article published on 01 January 2018

2-Aminoindan and its ring-substituted derivatives interact with plasma membrane monoamine transporters and α2-adrenergic receptors

scientific article published on 23 March 2019

5-(2-Aminopropyl)indole (5-IT): a psychoactive substance used for recreational purposes is an inhibitor of human monoamine oxidase (MAO).

scientific article

A qualitative/quantitative approach for the detection of 37 tryptamine-derived designer drugs, 5 β-carbolines, ibogaine, and yohimbine in human urine and plasma using standard urine screening and multi-analyte approaches.

scientific article published in November 2013

AMT (3-(2-aminopropyl)indole) and 5-IT (5-(2-aminopropyl)indole): an analytical challenge and implications for forensic analysis

scientific article

Addressing the challenges in forensic drug chemistry

scientific article published on 19 January 2017

Advancing supplement science: challenges and solutions

scientific article published on 01 March 2016

An analytical perspective on favoured synthetic routes to the psychoactive tryptamines

scientific article

An approach to shortening the timeframe between the emergence of new compounds on the drugs market and the availability of reference standards: The microscale syntheses of nitrazolam and clonazolam for use as reference materials, utilizing polymer-s

scientific article published on 15 March 2018

Analyses of second-generation 'legal highs' in the UK: initial findings.

scientific article

Analysis of NRG 'legal highs' in the UK: identification and formation of novel cathinones

scientific article

Analysis of psychoactive cathinones and tryptamines by electrospray ionization atmospheric pressure ion mobility time-of-flight mass spectrometry

scientific article

Analysis of six 'neuro-enhancing' phenidate analogs

scientific article published on 9 January 2017

Analytical characterisation of the routes by thermolytic decarboxylation from tryptophan to tryptamine using ketone catalysts, resulting in tetrahydro-beta-carboline formation.

scientific article

Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo and (±)-erythro diastereomers.

scientific article published on 19 January 2017

Analytical characterization and rapid determination of 2-(diphenylmethyl)pyrrolidine in blood and application to an internet product

article

Analytical characterization of N,N-diallyltryptamine (DALT) and 16 ring-substituted derivatives

scientific article

Analytical characterization of bioactive N-benzyl-substituted phenethylamines and 5-methoxytryptamines

scientific article published on April 2015

Analytical characterization of three trifluoromethyl-substituted methcathinone isomers.

scientific article

Analytical chemistry of synthetic routes to psychoactive tryptamines. Part I. Characterisation of the Speeter and Anthony synthetic route to 5-methoxy-N,N-diisopropyltryptamine using ESI-MS-MS and ESI-TOF-MS.

scientific article published in October 2004

Analytical chemistry of synthetic routes to psychoactive tryptamines. Part II. Characterisation of the Speeter and Anthony synthetic route to N,N-dialkylated tryptamines using GC-EI-ITMS, ESI-TQ-MS-MS and NMR.

scientific article

Analytical chemistry of synthetic routes to psychoactive tryptamines. Part III. Characterisation of the Speeter and Anthony route to N,N-dialkylated tryptamines using CI-IT-MS-MS.

scientific article published on 8 July 2005

Analytical profile of N-ethyl-N-cyclopropyl lysergamide (ECPLA), an isomer of lysergic acid 2,4-dimethylazetidide (LSZ)

scientific article published on 16 August 2020

Analytical techniques for the determination of tryptamines and β-carbolines in plant matrices and in psychoactive beverages consumed during religious ceremonies and neo-shamanic urban practices.

scientific article published on 11 May 2012

Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter.

scientific article

Biotransformation and detectability of the new psychoactive substances N,N-diallyltryptamine (DALT) derivatives 5-fluoro-DALT, 7-methyl-DALT, and 5,6-methylenedioxy-DALT in urine using GC-MS, LC-MSn, and LC-HR-MS/MS.

scientific article

Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry.

scientific article published on 23 June 2009

Characterization of a novel and potentially lethal designer drug (±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or 'Serotoni').

scientific article

Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry.

scientific article published on July 2010

Comparison of the behavioral effects of mescaline analogs using the head twitch response in mice

scientific article published on 21 February 2019

Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs

article

Conformational Evaluation of Indol-3-yl-N-alkyl-glyoxalylamides and Indol-3-yl-N,N-dialkyl-glyoxalylamides

scientific article published on 24 March 2009

Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species

scientific article published on 07 January 2020

Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class.

scientific article

DARK Classics in Chemical Neuroscience: Aminorex Analogues

scientific article published on 05 October 2018

Determination of N,N-dimethyltryptamine in beverages consumed in religious practices by headspace solid-phase microextraction followed by gas chromatography ion trap mass spectrometry.

scientific article

Drug laws and the 'derivative' problem

scientific article

Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties

scientific article (publication date: 2017)

Fingerprint analysis of thermolytic decarboxylation of tryptophan to tryptamine catalyzed by natural oils

scientific article published on 16 September 2008

First reported fatalities associated with the 'research chemical' 2-methoxydiphenidine.

scientific article

Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family

scientific article published on 6 October 2017

Forensic analysis of P2P derived amphetamine synthesis impurities: identification and characterization of indene by-products

scientific article published on 15 January 2016

From the street to the laboratory: analytical profiles of methoxetamine, 3-methoxyeticyclidine and 3-methoxyphencyclidine and their determination in three biological matrices.

scientific article

Halogenated solvent interactions with N,N-dimethyltryptamine: formation of quaternary ammonium salts and their artificially induced rearrangements during analysis.

scientific article published in May 2008

Identification and characterization of an imidazolium by-product formed during the synthesis of 4-methylmethcathinone (mephedrone).

scientific article published on April 2015

Identification of pyrolysis products of the new psychoactive substance 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone hydrochloride (bk-2C-B) and its iodo analogue bk-2C-I.

scientific article published on 31 March 2017

Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health.

scientific article

In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening procedures

scientific article published on 07 January 2019

In vitro metabolism of the synthetic cannabinoid 3,5-AB-CHMFUPPYCA and its 5,3-regioisomer and investigation of their thermal stability.

scientific article published on 17 February 2016

In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks

scientific article published on 14 March 2017

Interactions of phenethylamine-derived psychoactive substances of the 2C-series with human monoamine oxidases

scientific article published on 28 September 2018

Is nitrogen mustard contamination responsible for the reported MT-45 toxicity?

scientific article published on 02 July 2017

Is the breast cancer drug tamoxifen being sold as a bodybuilding dietary supplement?

scientific article published on 13 February 2014

Mephedrone. Banned but still available on the internet

scientific article published on 15 March 2011

Metabolic fate and detectability of the new psychoactive substances 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25B-NBOMe) and 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25C-NBOMe) in human and

scientific article published on 27 November 2016

Metabolic fate, mass spectral fragmentation, detectability, and differentiation in urine of the benzofuran designer drugs 6-APB and 6-MAPB in comparison to their 5-isomers using GC-MS and LC-(HR)-MS(n) techniques

scientific article published on 25 February 2015

Metabolism of Nine Synthetic Cannabinoid Receptor Agonists Encountered in Clinical Casework: Major in vivo Phase I Metabolites of AM-694, AM-2201, JWH-007, JWH-019, JWH-203, JWH-307, MAM-2201, UR-144 and XLR-11 in Human Urine Using LC-MS/MS

scientific article published on 01 January 2018

Metabolism of the new psychoactive substances N,N-diallyltryptamine (DALT) and 5-methoxy-DALT and their detectability in urine by GC-MS, LC-MSn, and LC-HR-MS-MS.

scientific article

Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS.

scientific article published on 24 March 2017

Microwave-accelerated preparation and analytical characterization of 5-ethoxy-N,N-dialkyl-[α,α,β,β-H4]- and [α,α,β,β-D4]-tryptamines

article

Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence

scientific article

Multiple fatalities involving a new designer drug: para-methyl-4-methylaminorex.

scientific article published on 15 May 2014

N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis.

scientific article

N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues

scientific article

New Psychoactive Substances 3-Methoxyphencyclidine (3-MeO-PCP) and 3-Methoxyrolicyclidine (3-MeO-PCPy): Metabolic Fate Elucidated with Rat Urine and Human Liver Preparations and their Detectability in Urine by GC-MS, "LC-(High Resolution)-MSn" and "

scientific article

Online test purchased new psychoactive substances in 5 different European countries: A snapshot study of chemical composition and price.

scientific article published in May 2017

Outsmarted by nootropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector: formation of 1,1,2,2-tetraphenylethane and its tetra fluoro analog

scientific article published on 8 December 2016

Pharmacokinetics and subjective effects of 1P-LSD in humans after oral and intravenous administration

scientific article published on 15 May 2020

Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues.

scientific article

Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD)

scientific article published on 19 November 2019

Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA)

scientific article published on 08 October 2018

Pharmacological characterizations of the 'legal high' fluorolintane and isomers

scientific article published on 29 May 2019

Pharmacological examination of trifluoromethyl ring-substituted methcathinone analogs

scientific article published on 21 November 2012

Pharmacological profile of methylphenidate-based designer drugs.

scientific article published on 17 August 2017

Phencyclidine-Based New Psychoactive Substances

scientific article published on 01 January 2018

Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screenings

scientific article published on 31 July 2019

Phenothiazinium photosensitisers VII: novel substituted asymmetric N-benzylphenothiaziniums as photoantimicrobial agents.

scientific article published on 16 February 2010

Potential antimalarial derivatives from astraodorol

scientific article published on 19 April 2014

Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products

scientific article published on 17 October 2012

Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues

scientific article

Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.

scientific article

Prodrugs of New Psychoactive Substances (NPS): A New Challenge

scientific article published on 13 January 2020

Receptor binding profiles and behavioral pharmacology of ring-substituted N,N-diallyltryptamine analogs.

scientific article published on 27 February 2018

Reinforcing and neurochemical effects of the "bath salts" constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats

scientific article published on 29 August 2015

Research on psychedelic substances

scientific article published on 6 July 2012

Return of the lysergamides. Part I: Analytical and behavioural characterization of 1-propionyl-d-lysergic acid diethylamide (1P-LSD)

scientific article

Return of the lysergamides. Part III: Analytical characterization of N6 -ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD).

scientific article published on 24 March 2017

Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775).

scientific article published on 5 June 2017

Return of the lysergamides. Part V: Analytical and behavioural characterization of 1-butanoyl-d-lysergic acid diethylamide (1B-LSD)

scientific article published on 18 June 2019

Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)

scientific article published on 16 March 2020

Ribonucleotide and ribonucleoside determination by ambient pressure ion mobility spectrometry.

scientific article

Salvia divinorum use and phenomenology: results from an online survey

scientific article published on 11 October 2010

Self-Experiments with Psychoactive Substances: A Historical Perspective

scientific article published on 01 January 2018

Special issue on illicit drugs ⬇️

scientific article published on 01 September 2011

Studies on the metabolism and toxicological detection of the new psychoactive designer drug 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) in human and rat urine using GC-MS, LC-MS(n), and LC-HR-MS/MS

scientific article published on 25 June 2015

Syntheses and analytical characterizations of N-alkyl-arylcyclohexylamines.

scientific article

Syntheses and analytical characterizations of novel (2-aminopropyl)benzo[b]thiophene (APBT) based stimulants

scientific article published on 05 May 2020

Syntheses and analytical characterizations of the research chemical 1-[1-(2-fluorophenyl)-2-phenylethyl]pyrrolidine (fluorolintane) and five of its isomers

scientific article published on 10 July 2019

Syntheses, analytical and pharmacological characterizations of the 'legal high' 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo) and analogues.

scientific article published on 16 May 2017

Synthesis and characterization of 5-methoxy-2-methyl-N,N-dialkylated tryptamines.

scientific article published in January 2012

Synthesis, analytical characterization and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers

scientific article published on 19 April 2018

Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.

scientific article

Synthesis, characterization, and monoamine transporter activity of the new psychoactive substance 3',4'-methylenedioxy-4-methylaminorex (MDMAR).

scientific article published on 20 October 2014

Synthetic cannabinoid receptor agonists: analytical profiles and development of QMPSB, QMMSB, QMPCB, 2F-QMPSB, QMiPSB, and SGT-233

scientific article published on 16 August 2020

Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B).

scientific article

Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers.

scientific article

Test purchase, synthesis, and characterization of 2-methoxydiphenidine (MXP) and differentiation from its meta- and para-substituted isomers.

scientific article

The confusing case of NRG-1

scientific article published in the British Medical Journal

The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue

scientific article

The first reported fatality associated with the synthetic opioid 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) and implications for forensic analysis

scientific article published on 27 May 2016

The naphyrone story: The alpha or beta-naphthyl isomer?

scientific article

The new drug phenomenon

scientific article published on 03 July 2014

The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue

scientific article

The psychoactive aminoalkylbenzofuran derivatives, 5-APB and 6-APB, mimic the effects of 3,4-methylenedioxyamphetamine (MDA) on monoamine transmission in male rats

scientific article published on 01 September 2020

The psychostimulant (±)-cis-4,4'-dimethylaminorex (4,4'-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters

scientific article published on 23 June 2018

The synthesis and characterization of the 'research chemical' N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.

scientific article

Validation of an LC-MS/MS method for the quantitative analysis of 1P-LSD and its tentative metabolite LSD in fortified urine and serum samples including stability tests for 1P-LSD under different storage conditions

scientific article published on 28 May 2019

Who said practice makes perfect?

scientific article published on 01 January 1989

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