Search filters

List of works by Gary J. Gorbsky

A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor

scientific article

CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation

scientific article published on 14 February 2019

Cell-cycle-regulated localization of tyrosine and threonine phosphoepitopes at the kinetochores of mitotic chromosomes.

scientific article

Chondrosarcoma-associated gene 1 (CSAG1) maintains the integrity of the mitotic centrosome in cells with defective p53

scientific article published on 15 April 2020

Cohesion fatigue.

scientific article published in November 2013

Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint

scientific article

Duct tape for broken chromosomes.

scientific article published in January 2010

Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.

scientific article

Expression of HPV16 E5 produces enlarged nuclei and polyploidy through endoreplication.

scientific article

GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms

scientific article published on 18 August 2017

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

scientific article

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis

scientific article

Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion.

scientific article

ICIS and Aurora B coregulate the microtubule depolymerase Kif2a

scientific article

Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons

scientific article

Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis

scientific article (publication date: 4 June 2002)

Is the movement of single cells within solid tissue masses induced by trypsinization?

scientific article published on 01 December 1976

Isolation of the non-glycosylated proteins of desmosomes and immunolocalization of a third plaque protein: desmoplakin III.

scientific article published on February 1985

Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint ⬇️

scientific article published on August 1, 1995

Live-cell fluorescence imaging for phenotypic analysis of mitosis

scientific article

Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.

scientific article published on June 1999

Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase

scientific article

Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited

scientific article

Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin

scientific article

PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles

scientific article

Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.

scientific article published on 5 October 2017

Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores

scientific article

Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis

scientific article

Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis

scientific article

The 3F3/2 anti-phosphoepitope antibody binds the mitotically phosphorylated anaphase-promoting complex/cyclosome

scientific article published on 01 November 2000

The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity

scientific article

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

scientific article

The mitotic spindle checkpoint

scientific article published on 01 December 2001

The reversibility of mitotic exit in vertebrate cells

scientific article

The spindle and kinetochore-associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit

scientific article published on 08 January 2014

The spindle checkpoint and chromosome segregation in meiosis

scientific article

The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment

scientific article

Paulina is supported by:

About Paulina

Help