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List of works by Chai K Lim

A brief diet intervention can reduce symptoms of depression in young adults - A randomised controlled trial

scientific article published on 09 October 2019

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality

scientific article published on 12 August 2014

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

scientific article published on 30 May 2015

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study.

scientific article published on 22 May 2018

Altered kynurenine pathway metabolism in autism: Implication for immune-induced glutamatergic activity.

scientific article published on 24 October 2015

Antibodies to MOG have a demyelination phenotype and affect oligodendrocyte cytoskeleton.

scientific article

Characterization of the Kynurenine Pathway in CD8+ Human Primary Monocyte-Derived Dendritic Cells.

scientific article

Characterization of the kynurenine pathway and quinolinic Acid production in macaque macrophages.

scientific article published on 15 May 2013

Characterization of the kynurenine pathway in human neurons

scientific article published on November 2007

Connecting inflammation with glutamate agonism in suicidality.

scientific article published on 3 December 2012

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

scientific article published on 01 April 2019

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis

scientific article

Does escitalopram reduce neurotoxicity in major depression?

scientific article published on 12 May 2015

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia

scientific article published on 03 April 2019

Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition

scientific article published on 27 May 2014

Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota

scientific article published on 17 July 2019

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

scientific article published on 26 June 2015

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

scientific article published on 2 August 2017

Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression

scientific article published on 05 November 2019

Involvement of the kynurenine pathway in human glioma pathophysiology

scientific article

Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease

scientific article published on 9 April 2016

Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms

scientific article published on 21 January 2019

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

scientific article published on 03 February 2017

Kynurenines, Gender and Neuroinflammation; Showcase Schizophrenia

scientific article published on 24 June 2016

Loss of the Chr16p11.2 ASD candidate gene leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model

article

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

scientific article published in August 2017

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes

scientific article published on 30 November 2017

Neurotoxicity of the Cyanotoxin BMAA Through Axonal Degeneration and Intercellular Spreading.

scientific article published on 25 August 2017

Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease

scientific article published on 10 October 2019

Progesterone Alters Kynurenine Pathway Activation in IFN-γ-Activated Macrophages - Relevance for Neuroinflammatory Diseases.

scientific article published on 07 December 2016

Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class.

scientific article published on 18 April 2008

Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells

scientific article

Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

scientific article

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases.

scientific article published on 16 March 2016

Renal denervation does not affect hypertension or the renin-angiotensin system in a rodent model of juvenile-onset polycystic kidney disease: clinical implications

scientific article published on 12 July 2021

Role of NAD(+), Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders

scientific article published on 21 July 2013

Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility

scientific article published on 12 February 2016

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66.

scientific article published on 29 January 2016

The kynurenine pathway of tryptophan degradation is activated during osteoblastogenesis.

scientific article published in January 2015

Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis

scientific article published on 8 June 2018

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

scientific article

Understanding the roles of the kynurenine pathway in multiple sclerosis progression.

scientific article published on 25 August 2010

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