List of works by Michael Toft Overgaard

A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment

scientific journal article

A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen: establishment of normal ranges in pregnancy

scientific article published on 25 June 2013

ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity.

scientific article published on 10 June 2013

Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients

scientific article

Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures

scientific article published on 02 April 2019

AnOxPePred: using deep learning for the prediction of antioxidative properties of peptides

scientific article published on 08 December 2020

Antimicrobial peptide CAP18 and its effect on Yersinia ruckeri infections in rainbow trout Oncorhynchus mykiss (Walbaum): comparing administration by injection and oral routes.

scientific article published on 23 June 2016

Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+ binding and cause misfolding

scientific article published on 18 February 2020

Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel

article published in the Proceedings of the National Academy of Sciences of the United States of America

Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release

scientific article published on 26 August 2015

Beating tissue factor at its own game: Design and properties of a soluble tissue factor-independent coagulation factor VIIa

scientific article published on 04 December 2019

Biochemical Foundations of Health and Energy Conservation in Hibernating Free-ranging Subadult Brown Bear Ursus arctos

scientific article published on 8 September 2016

Biochemical evidence for heme linkage through esters with Asp-93 and Glu-241 in human eosinophil peroxidase. The ester with Asp-93 is only partially formed in vivo

scientific article

Biochemical mechanism of action of a diketopiperazine inactivator of plasminogen activator inhibitor-1.

scientific article published on August 2003

Biofunctionality of Enzymatically Derived Peptides from Codfish (<i>Gadus morhua</i>) Frame: Bulk In Vitro Properties, Quantitative Proteomics, and Bioinformatic Prediction

scientific article published on 27 November 2020

Biological age of the endometrium using DNA methylation

scientific article

Ca-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

scientific article published in 2019

Calmodulin in a heartbeat

scientific article published on 18 June 2013

Calmodulin mutations associated with long QT syndrome prevent inactivation of cardiac L-type Ca(2+) currents and promote proarrhythmic behavior in ventricular myocytes

scientific article published on 8 May 2014

Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes

scientific article published on 14 January 2015

Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module

scientific article published on April 2004

Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.

scientific article published on 4 October 2002

Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin

scientific article published on 13 December 2021

Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria

scientific article published on 11 December 2015

Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP

scientific article

Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment

scientific article (publication date: 24 January 2003)

Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.

scientific article published on January 2006

Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules

scientific article

Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells.

scientific article

Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

scientific article published on 12 July 2019

Dissection of the antimicrobial and hemolytic activity of Cap18: Generation of Cap18 derivatives with enhanced specificity.

scientific article published on 31 May 2018

Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors.

scientific article

Evidence that the insulin-like growth factor binding protein-4 protease in human ovarian follicular fluid is pregnancy associated plasma protein-A

scientific article published on 01 December 1999

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

scientific article

Expression of recombinant human pregnancy-associated plasma protein-A and identification of the proform of eosinophil major basic protein as its physiological inhibitor

scientific article

Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity

scientific journal article

Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex

scientific article

Human Calmodulin Mutations

scientific article published on 13 November 2018

IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.

scientific article published in March 2013

IGFBP-4 degradation by pregnancy-associated plasma protein-A in MC3T3 osteoblasts

scientific article

Identification and regulation of the IGFBP-4 protease and its physiological inhibitor in human trophoblasts and endometrial stroma: evidence for paracrine regulation of IGF-II bioavailability in the placental bed during human implantation.

scientific article

Identification of emulsifier potato peptides by bioinformatics: application to omega-3 delivery emulsions and release from potato industry side streams

scientific article published on 20 January 2020

Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase

scientific article published on February 2004

Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding

scientific article

Insulin-like growth factor binding protein-4 protease produced by smooth muscle cells increases in the coronary artery after angioplasty

scientific article published on 01 March 2001

Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility

scientific article

Localization and regulation of pregnancy-associated plasma protein a expression in healing human skin.

scientific article published in September 2003

Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues

scientific article (publication date: October 1999)

Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development.

scientific article published in March 2004

Molecular Basis of Enhanced Activity in Factor VIIa-Trypsin Variants Conveys Insights into Tissue Factor-mediated Allosteric Regulation of Factor VIIa Activity

scientific article published on 22 December 2015

Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women

scientific article

Molecular regulation of the IGF-binding protein-4 protease system in human fibroblasts: identification of a novel inducible inhibitor

scientific article (publication date: April 2002)

Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

scientific article published on 29 November 2017

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin

scientific journal article

Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death

scientific article

Participation of mitogen-activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles

scientific article

Plasma proteomics data from hibernating and active Scandinavian brown bears

publication published on 16 February 2022

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ovine, Bovine, Porcine, and Equine Ovarian Follicles: Involvement in IGF Binding Protein-4 Proteolytic Degradation and mRNA Expression During Follicular Development

scientific article published on 01 December 2001

Pregnancy-associated plasma protein A and its endogenous inhibitor, the proform of eosinophil major basic protein (proMBP), are related to complex stenosis morphology in patients with stable angina pectoris

scientific article (publication date: 13 April 2004)

Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane.

scientific article published in November 2002

Pregnancy-associated plasma protein a gene expression as a target of inflammatory cytokines.

scientific article published on 4 December 2003

Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A

scientific journal article

Pregnancy-associated plasma protein-A (PAPP-A) expression and insulin-like growth factor binding protein-4 protease activity in normal and malignant ovarian surface epithelial cells.

scientific article published on July 2004

Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degrada

scientific article published on 01 January 2003

Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase

scientific article

Pregnancy-associated plasma protein-a is the insulin-like growth factor binding protein-4 protease secreted by human ovarian granulosa cells and is a marker of dominant follicle selection and the corpus luteum

scientific article published on 01 May 2001

Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements.

scientific article

Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles

scientific article published on 01 September 2004

Quantification and characterization of pregnancy-associated complexes of angiotensinogen and the proform of eosinophil major basic protein in serum and amniotic fluid

scientific article published on 01 August 2000

Regulation of Human ADAM 12 Protease by the Prodomain

scientific article published in Journal of Biological Chemistry

Relationship among pregnancy associated plasma protein-A levels, clinical characteristics, and coronary artery disease extent in patients with chronic stable angina pectoris

scientific article published on 29 July 2005

Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I

scientific article published on 25 November 2019

Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers.

scientific article published in January 2004

Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2.

scientific article published on 25 September 2008

Simple and reliable procedure for PCR amplification of genomic DNA from yeast cells using short sequencing primers

scientific article published on 01 June 1997

Study of the tryptophan-terbium FRET pair coupled to silver nanoprisms for biosensing applications.

scientific article published on 3 May 2013

Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis

scientific article published on October 2002

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

scientific article published on 07 December 2016

The Bacillus subtilis RNA helicase YxiN is distended in solution

scientific article

The GH–IGF–IGFBP axis is changed in Turner syndrome: Partial normalization by HRT

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic

scientific article

The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat

scientific article published on 22 December 2015

The International Calmodulinopathy Registry: recording the diverse phenotypic spectrum of un-CALM hearts

scientific article published on 01 September 2019

The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity

scientific article published on 15 July 2004

The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-domain, altering its interaction with the cardiac ryanodine receptor

scientific article published on 21 April 2020

The brown bear as a translational model for sedentary lifestyle-related diseases

scientific article published on 24 October 2019

The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold

scientific article

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

scientific article

The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential

scientific article

The proform of eosinophil major basic protein: a new maternal serum marker for Down syndrome

scientific article published on 01 October 1999

Therapeutic endometrial scratching and implantation after in vitro fertilization: a multicenter randomized controlled trial

scientific article published on 01 December 2019

Transforming growth factor-beta regulation of the insulin-like growth factor binding protein-4 protease system in cultured human osteoblasts

scientific article

Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development

scientific article

Up date on IGFBP-4: regulation of IGFBP-4 levels and functions, in vitro and in vivo

scientific article published on April 2004

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