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List of works by Eleanor J. Mackie

A T cell-specific knockout reveals an important role for protease-activated receptor 2 in lymphocyte development.

scientific article published on 22 September 2017

Activation of protease-activated receptor-2 leads to inhibition of osteoclast differentiation

scientific article published on 22 December 2003

Adhesive properties of isolated chick osteocytes in vitro

scientific article published on 01 April 1996

Altered gene expression in early osteochondrosis lesions

article

Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

scientific article published on 04 November 2019

Can high-resolution peripheral quantitative computed tomography imaging of subchondral and cortical bone predict condylar fracture in Thoroughbred racehorses?

scientific article

Chondrocytic ephrin B2 promotes cartilage destruction by osteoclasts in endochondral ossification.

scientific article published on 11 January 2016

Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis

article

Comparison of the distribution patterns of tenascin and alkaline phosphatase in developing teeth, cartilage, and bone of rats and mice.

scientific article published in September 1990

Comprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics

scientific article

Contractile properties of slow and fast skeletal muscles from protease activated receptor-1 null mice

scientific article published on 30 October 2014

Disrupted type II collagenolysis impairs angiogenesis, delays endochondral ossification and initiates aberrant ossification in mouse limbs

scientific article published on 02 August 2019

Dissection of Protease-Activated Receptor-1-Dependent and -Independent Responses to Thrombin in Skeletal Myoblasts

article

Endochondral ossification: how cartilage is converted into bone in the developing skeleton.

scientific article published on 29 June 2007

EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis.

scientific article published on 30 June 2014

Erratum to “Inhibition of osteoblast apoptosis by thrombin” [Bone 33 (2003) 733–743]

scholarly article published in Bone

Establishment of a Model of Cortical Bone Repair in Mice

scientific article published on 01 July 2003

Evaluation of antibodies directed against human protease-activated receptor-2.

scientific article published on 31 July 2012

Evidence for the activation of PAR-2 by the sperm protease, acrosin: expression of the receptor on oocytes

scientific article published in November 2000

Exercise-induced inhibition of remodelling is focally offset with fatigue fracture in racehorses

article

Expression of Tenascin-C in Bones Responding to Mechanical Load ⬇️

scientific article published on January 1, 1997

Expression of protease-activated receptor-2 by osteoblasts.

scientific article

Expression of protease-activated receptor-2 during embryonic development

article

Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopecia areata

scientific article published on 01 January 1991

Expression of the thrombin receptor in developing bone and associated tissues

scientific article published in May 1998

Functional responses of bone cells to thrombin

scientific article published on August 2006

Growth Plate Borderline Chondrocytes: A New Source of Metaphyseal Mesenchymal Precursors

scientific article published on 22 July 2019

High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism

scientific article

Hyaluronan synthesis and myogenesis: a requirement for hyaluronan synthesis during myogenic differentiation independent of pericellular matrix formation

scientific article published on 14 March 2013

Hypertrophy and physiological death of equine chondrocytes in vitro

scientific article published on 01 November 2007

Identification of novel osteochondrosis--Associated genes.

scientific article

Immunohistochemical localization of a tenascin-like extracellular matrix protein in sea urchin embryos

scientific article

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

scientific article published on 31 July 2019

Inhibition of osteoblast apoptosis by thrombin

scientific article published on October 2003

Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study

scientific article published in May 2010

Keratinocyte-specific ablation of protease-activated receptor 2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease

scientific article published on 31 July 2018

Modulation of Osteoblast-like Cell Behavior by Activation of Protease-Activated Receptor-1

scientific article published on 01 August 1999

Myoblasts isolated from hypertrophy-responsive callipyge muscles show altered growth rates and increased resistance to serum deprivation-induced apoptosis

scientific article published on 23 October 2007

Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells

scientific article published on 26 February 2019

Osteopontin and skeletal muscle myoblasts: association with muscle regeneration and regulation of myoblast function in vitro

scientific article

Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury

scientific article

Osteopontin, inflammation and myogenesis: influencing regeneration, fibrosis and size of skeletal muscle

scientific article

Periostin expression distinguishes between light and dark hypertrophic chondrocytes

scientific article published on 18 January 2010

Physiological death of hypertrophic chondrocytes.

scientific article

Prevalence of subchondral bone pathological changes in the distal metacarpi/metatarsi of racing Thoroughbred horses.

scientific article published in October 2017

Protease-Activated Receptor-1 Down-regulates the Murine Inflammatory and Humoral Response to Helicobacter pylori

scientific article published on 23 August 2009

Protease-activated receptor 2 has pivotal roles in cellular mechanisms involved in experimental periodontitis

scientific article

Protease-activated receptors: a means of converting extracellular proteolysis into intracellular signals.

scientific article

Proteinase-activated receptor-2 (PAR2) and mouse osteoblasts: regulation of cell function and lack of specificity of PAR2-activating peptides

scientific article published on 21 September 2009

Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair.

scientific article published on 7 December 2011

Regulation of Tenascin-C Expression in Bone Cells by Transforming Growth Factor-β ⬇️

scientific article published on April 1, 1998

Responses in vivo to purified poly(3-hydroxybutyrate-co-3-hydroxyvalerate) implanted in a murine tibial defect model.

scientific article published in December 2009

Role of subchondral bone remodelling in collapse of the articular surface of Thoroughbred racehorses with palmar osteochondral disease

scientific article published on 13 January 2015

Studies on the receptors mediating responses of osteoblasts to thrombin.

scientific article published in January 2005

Subchondral bone microdamage accumulation in distal metacarpus of Thoroughbred racehorses

scientific article published on 12 May 2018

Tenascin expression in basal cell carcinoma

scientific article published on December 1, 1992

Tenascin expression in hyperproliferative skin diseases.

scientific article

Tenascin-C induced stimulation of chondrogenesis is dependent on the presence of the C-terminal fibrinogen-like globular domain.

scientific article

The antiepileptic medications carbamazepine and phenytoin inhibit native sodium currents in murine osteoblasts.

scientific article published on 21 July 2016

The differential effects of stanozolol on human skin and synovial fibroblastsin vitro: DNA synthesis and receptor binding

scientific article published on 01 March 1994

The gingipains from Porphyromonas gingivalis do not directly induce osteoclast differentiation in primary mouse bone marrow cultures.

scientific article

The role of tenascin-C and related glycoproteins in early chondrogenesis

scientific article published on 01 October 1998

The skeleton: a multi-functional complex organ: the growth plate chondrocyte and endochondral ossification.

scientific article published on 03 June 2011

The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation

scientific article published on 18 August 2017

Third metacarpal condylar fatigue fractures in equine athletes occur within previously modelled subchondral bone

scientific article published on 24 July 2010

Thoroughbred horses in race training have lower levels of subchondral bone remodelling in highly loaded regions of the distal metacarpus compared to horses resting from training

scientific article published on 21 September 2014

Thrombin inhibits osteoclast differentiation through a non-proteolytic mechanism.

scientific article published on 23 April 2013

Thrombin is a pro-fibrotic factor for rat renal fibroblasts in vitro.

scientific article published on 7 June 2005

Thrombin, a Survival Factor for Cultured Myoblasts

scientific article published in Journal of Biological Chemistry

Thrombin-stimulated growth factor and cytokine expression in osteoblasts is mediated by protease-activated receptor-1 and prostanoids

scientific article

Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy

scientific article

Tumour progression and cancer-induced pain: a role for protease-activated receptor-2?

scientific article

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