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List of works by António Coutinho

"In vivo" activated splenic T cells are refractory to interleukin 2 growth "in vitro"

scientific article published on 01 July 1987

A Model of the Immune Network with B-T Cell Co-operation. II—The Simulation of Ontogenesis

scientific article published on 01 October 1996

A functional idiotypic network of T helper cells and antibodies, limited to the compartment of "naturally" activated lymphocytes in normal mice.

scientific article published on June 1987

A missing dimension in measures of vaccination impacts

scientific article

A remarkable depletion of both naïve CD4+ and CD8+ with high proportion of memory T cells in an IPEX infant with a FOXP3 mutation in the forkhead domain.

scientific article

Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice

scientific article

Administration to mouse of endotoxin from gram-negative bacteria leads to activation and apoptosis of T lymphocytes.

scientific article published in February 1998

An example of idiotypic mimicry

scientific article published on 01 July 1997

Analysis of the natural human IgG antibody repertoire: life-long stability of reactivities towards self antigens contrasts with age-dependent diversification of reactivities against bacterial antigens

scientific article published on 01 September 1995

B lymphocyte activation upon exclusive recognition of major histocompatibility antigens by T helper cells

scientific article published on 01 March 1984

B lymphocyte sensitivity to IgM receptor ligation is independent of maturation stage and locally determined by macrophage-derived IFN-beta

scientific article published in November 1997

B-cell growth factor: distinction from T-cell growth factor and B-cell maturation factor.

scientific article

B-lineage cell deficits in bone marrow of lpr/lpr mice

scientific article published on 01 February 1996

Characteristic generated alterations of autoantibody patterns in idiopathic thrombocytopenic purpura.

scientific article

Decreased AIRE expression and global thymic hypofunction in Down syndrome.

scientific article

Differential sensitivity of B lymphocyte populations to IgM receptor ligation is determined by local factors

scientific article published in May 1997

Expression of V-region-like determinants on Ig-negative precursors in murine fetal liver and bone marrow

scientific article published on July 19, 1979

Functional diversity and clonal frequencies of reactivity in the available antibody repertoire

scientific article published on 01 April 1998

Further evidence for coelomic-associated B lymphocytes

scientific article published on 01 November 1989

Genetic control of natural antibody repertoires: I. IgH, MHC and TCR beta loci

scientific article published on 01 March 1998

Global analysis of antibody repertoires. 1. An immunoblot method for the quantitative screening of a large number of reactivities.

scientific article published in January 1994

Global analysis of antibody repertoires. II. Evidence for specificity, self-selection and the immunological "homunculus" of antibodies in normal serum

scientific article published on 01 November 1993

Immunity to microbes: lessons from primary immunodeficiencies.

scientific article published on 5 February 2007

Immunophenotypic aberrations, DNA content, and cell cycle analysis of plasma cells in patients with myeloma and monoclonal gammopathies.

scientific article

Increased IgE serum levels are unrelated to allergic and parasitic diseases in patients with juvenile systemic lupus erythematosus

scientific article

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype ⬇️

scientific article published on August 1, 1995

Maternal IgG stimulates B lineage cell development in the progeny

scientific article published on 01 March 1997

Maternal transmission of idiotypic network interactions selecting available T cell repertoires

article

Metabolic adaptation to tissue iron overload confers tolerance to malaria

scientific article published in November 2012

Natural autoantibodies.

scientific article published on December 1995

Naturally activated CD4+ T cells are highly enriched for cytokine-producing cells ⬇️

scientific article published on June 1, 1998

Negative selection of multireactive B cell clones in normal adult mice

scientific article published on 01 June 1994

Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires ⬇️

scientific article published on July 1, 1991

Physiopathology of natural auto-antibodies: the case for regulation

scientific article published on December 2007

Population dynamics of natural antibodies in normal and autoimmune individuals.

scientific article published on July 1991

Quantitative analysis of multiple V-region interactions among normal human IgG

scholarly article by Ahidjo Ayouba et al published April 1996 in European Journal of Immunology

Regulatory T cells in microbial infection

scientific article published on 28 July 2006

Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T cells

scientific article published on 01 September 1995

Selective peripheral expansion and activation of B cells expressing endogenous immunoglobulin in mu-transgenic mice

scientific article published on 01 May 1990

Selectivity of Recognition of Variable (V) Regions of Autoantibodies by Intravenous Immunoglobulin (IVIg)

scientific article published in February 1994

Self-reactive antibodies (natural autoantibodies) in healthy individuals

scientific article published on 01 July 1998

Simple developmental programs of gene expression and cellular composition of lymphoid organs at the origin of natural tolerance.

scientific article published on May 1995

Speculations on immunosomatics: potential diagnostic and therapeutic value of immune homeostasis concepts

scientific article published on 01 October 1992

Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen ⬇️

scientific article published on June 1, 1976

Steroid treatments in mice do not alter the number and function of regulatory T cells, but amplify cyclophosphamide-induced autoimmune disease

scientific article

Stimulation of B and T cells by in vivo high dose immunoglobulin administration in normal mice

scientific article published on 01 April 1991

Studies on the T cell dependence of natural IgM and IgG antibody repertoires in adult mice

scientific article published on 01 May 1995

Targeted disruption of the V(H) 81X gene: influence on the B cell repertoire.

scientific article published in January 1997

The network theory: 21 years later.

scientific article published in July 1995

The repertoire of serum IgM in normal mice is largely independent of external antigenic contact

scientific article published on 01 June 1997

Thymic epithelium induces full tolerance to skin and heart but not to B lymphocyte grafts

scientific article published on 01 February 1995

Tolerize one, tolerize them all: tolerance is self-assertion

scientific article published on 01 August 1989

Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.

scientific article

Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system.

scientific article

Type I IFN sets the stringency of B cell repertoire selection in the bone marrow

scientific article published in February 1999

VH-gene family dominance in ageing mice.

scientific article published on February 1994

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