List of works by Antonio Lanzavecchia

110 Broadly neutralizing antibodies for serotherapy and vaccine design.

scientific article

A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential

scientific article published on September 2017

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens

scientific article published on 23 December 2015

A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 9 November 2015

A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

scientific article published on 01 November 1997

A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression

scientific article published on 22 May 2006

A functional BCR in human IgA and IgM plasma cells

scientific article published on 2 April 2013

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

scientific article

A novel and simple procedure for determining T cell epitopes in protein antigens

scientific article published in August 1989

A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing

scientific article

A perspective on potential antibody-dependent enhancement of SARS-CoV-2

scientific article published on 13 July 2020

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

scientific article

A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

scientific article published on 27 May 2021

A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells

scientific article published on 30 January 2003

A shift in the phenotype of melan-A-specific CTL identifies melanoma patients with an active tumor-specific immune response

scientific article

A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients

scientific article published on 09 September 2019

A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding

scientific article

ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells

scientific article

ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies

scientific article published on 12 August 2022

Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation

scientific article published on 01 October 2003

Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development

scientific article

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

scientific article published on 26 October 2017

Adoptive immunotherapy of ovarian carcinoma with bs-MAb-targeted lymphocytes: a multicenter study

scientific article published on January 1, 1992

Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation

scientific article published on 01 July 1997

An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor

scientific article published on 26 July 2018

An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV

scientific article

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

scientific article published on 11 July 2004

An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells

scientific article published on 10 September 2018

An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells

scientific article published on September 1994

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

scientific article

AncesTree: An interactive immunoglobulin lineage tree visualizer

scientific article published on 10 July 2020

Anti-ovarian carcinoma anti-T3 heteroconjugates or hybrid antibodies induce tumor cell lysis by cytotoxic T-cells.

scientific article published in January 1988

Antibodies against neutralization epitopes of human cytomegalovirus gH/gL/pUL128-130-131 complex and virus spreading may correlate with virus control in vivo

scientific article published on 27 July 2012

Antibodies as antigens. The use of mouse monoclonal antibodies to focus human T cells against selected targets.

scientific article published on February 1988

Antibody-driven design of a human cytomegalovirus gHgLpUL128L subunit vaccine that selectively elicits potent neutralizing antibodies

scientific article

Antibody-guided vaccine design: identification of protective epitopes

scientific article

Antigen dependent and independent mechanisms that sustain serum antibody levels

scientific article

Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions

scientific article published on 01 June 1991

Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets

scientific article

Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 01 July 2020

BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction

scientific article

Broad betacoronavirus neutralization by a stem helix–specific human antibody

scientific article

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

scientific article

Broadly neutralizing antiviral antibodies

scientific article

Broadly reactive human CD4+ T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire

scientific article published on 23 November 2020

C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

scientific article

CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function

scientific article

CD34+ Hematopoietic Progenitors From Human Cord Blood Differentiate Along Two Independent Dendritic Cell Pathways in Response to Granulocyte-Macrophage Colony-Stimulating Factor Plus Tumor Necrosis Factor α: II. Functional Analysis

scientific article published on 15 August 1997

CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection

scientific article

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor alpha: II. Functional analysis

article

CD4+ CD25+ Treg regulate the contribution of CD8+ T-cell subsets in repopulation of the lymphopenic environment

scientific article published on 11 November 2010

CD40 ligand-independent B cell activation revealed by CD40 ligand-deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation

scientific article published on 01 June 1995

CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming

scientific article published on 06 October 2008

Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells.

scientific article published in April 2008

Central memory and effector memory T cell subsets: function, generation, and maintenance

scientific article (publication date: 2004)

Characterization of neutralizing profiles in HIV-1 infected patients from whom the HJ16, HGN194 and HK20 mAbs were obtained

scientific article

Characterization of severe acute respiratory syndrome coronavirus membrane protein

scientific article published on 19 January 2006

Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells

scientific article

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

scientific article published on 01 December 1998

Cholera toxin induces maturation of human dendritic cells and licences them for Th2 priming

scientific article published on 01 August 2000

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

scientific article published on 15 November 2010

Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

Clonal dissection of the human memory B-cell repertoire following infection and vaccination

scientific article published on May 2009

Clonal expansions of V delta 1+ and V delta 2+ cells increase with age and limit the repertoire of human gamma delta T cells

scientific article published on 01 August 1994

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

scientific article

Common variable immunodeficiency: long term clinical consequencies of splenectomy in a case of late-onset hypogammaglobulinaemia ⬇️

scientific article published on June 1, 1978

Concanavalin A induces a T-cell dependent activation of human tonsil B cells in vitro

scientific article published on 01 January 1980

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

scientific article published in January 2018

Correction: In-Depth Analysis of the Antibody Response of Individuals Exposed to Primary Dengue Virus Infection

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C

scientific article published in PLoS ONE

Correction: Systems Analysis of MVA-C Induced Immune Response Reveals Its Significance as a Vaccine Candidate against HIV/AIDS of Clade C.

scientific article published on 17 May 2012

Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells.

scientific article

Correction: Therapeutic Efficacy of Antibodies Lacking Fc. Receptor Binding against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies.

scientific article published on 27 March 2013

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

scientific article published on 18 May 2020

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

scientific article published on 18 August 2013

Crystal Structure and Size-Dependent Neutralization Properties of HK20, a Human Monoclonal Antibody Binding to the Highly Conserved Heptad Repeat 1 of gp41

scientific article

Current Opinion in Immunology. Vaccines. Introduction.

scientific article published on 24 May 2010

Cutting edge: recombinase-activating gene expression and V(D)J recombination in CD4+CD3low mature T lymphocytes

scientific article published on 01 April 2000

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

scientific article

Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin

scientific article published on 01 October 2020

Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge

scientific article published on 11 March 2015

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

scientific article published on May 1997

Delineation of several DR-restricted tetanus toxin T cell epitopes

scientific article published on 01 January 1989

Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells

scientific article published in February 2000

Dendritic cell migration to peripheral lymph nodes

scientific article published on January 2009

Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice

article

Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation

scientific article published on 01 December 1999

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

scientific article

Development of a human adaptive immune system in cord blood cell-transplanted mice

scientific article published in April 2004

Development of broad-spectrum human monoclonal antibodies for rabies post-exposure prophylaxis

scientific article

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

scientific article published on April 1996

Dissecting human antibody responses: useful, basic and surprising findings

scientific article published on 23 January 2018

Dissecting the human T and B cell response to pathogens.

scientific article

Dissecting the human immunologic memory for pathogens

scientific article published on March 2011

Distinct patterns and kinetics of chemokine production regulate dendritic cell function.

scientific article

Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate.

scientific article published in August 2007

Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? T-Cell Heterogeneity, Plasticity, and Selection in Humans

scientific article published on 21 April 2017

Dual receptor T-cells. Implications for alloreactivity and autoimmunity.

scientific article published on July 1995

Duration, combination and timing: the signal integration model of dendritic cell activation

scientific article published on 2 April 2007

Dynamics in protein translation sustaining T cell preparedness

scientific article published on 06 July 2020

ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells

scientific article published on 16 March 2015

Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells

scientific article published on October 2014

Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells ⬇️

scientific article published on February 1, 1991

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

scientific article

Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity

scientific article

Enforced STAT3 and PU.1 Expression Activates Type I Interferon-Producing Cell and Dendritic Cell Differentiation Programs in Megakaryocyte/Erythrocyte Progenitors. ⬇️

scholarly article

Erratum: Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

scientific article published on 01 April 2016

Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus

scientific article

Establishment of human double-positive thymocyte clones

scientific article published on July 1989

Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses

scientific article

Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells

scientific article published on 18 May 2016

Expression of two T cell receptor alpha chains: dual receptor T cells

scientific article published in Science

Fetal human cytomegalovirus transmission correlates with delayed maternal antibodies to gH/gL/pUL128-130-131 complex during primary infection

scientific article

Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes

scientific article

Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors

scientific article published in June 2003

From TCR Engagement to T Cell Activation

scientific article published on 01 January 1999

From synapses to immunological memory: the role of sustained T cell stimulation

scientific article

From vaccines to memory and back

scientific article published on October 2010

Functional analysis of two tetanus toxin universal T cell epitopes in their interaction with DR1101 and DR1104 alleles

scientific article published on 01 March 1994

Functional subsets of memory T cells identified by CCR7 expression

scientific article (publication date: 2000)

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

scientific article

Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity

scientific article published on August 2009

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

scientific article

High throughput cellular screens to interrogate the human T and B cell repertoires

scientific article

High-avidity IgA protects the intestine by enchaining growing bacteria

scientific article published on 12 April 2017

Homeostatic Proliferation of Chronic Lymphocytic Leukemia. ⬇️

scholarly article

Human B cell memory

scientific article published on 06 June 2009

Human T lymphocyte subset identification according to avidity for sheep erythrocytes and rosetting capacity with allogeneic red blood cells

scientific article published on July 31, 1977

Human Th17 cells in infection and autoimmunity

scientific article published on 14 April 2009

Human Th17 subsets

scientific article published on September 2012

Human adaptive immune system Rag2-/-gamma(c)-/- mice

scientific article

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

scientific article

Human monoclonal antibodies by immortalization of memory B cells

scientific article published on 11 December 2007

Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

scientific article

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

scientific article published on 14 December 2006

Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation

scientific article published on 01 September 2020

Identification of HLA-DR alpha chain residues critical for binding of the toxic shock syndrome toxin superantigen ⬇️

scientific article published on December 1, 1992

Identification of a Novel Non-desmoglein Autoantigen in Pemphigus Vulgaris

scientific article published on 19 June 2019

Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae

scientific article published on 8 December 2017

Immune subversion by Helicobacter pylori

scientific article

Immunogenetic mechanisms driving norovirus GII.4 antigenic variation

scientific article

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

scientific article published on 11 November 2022

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors

scientific article (publication date: 15 February 2011)

In vivo persistence of expanded clones specific for bacterial antigens within the human T cell receptor alpha/beta CD4-8- subset

scientific article published on June 1993

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection

scientific article

Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles

scientific article published on 01 November 2019

Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming

scientific article published on 07 November 2004

Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus

article

Infections and Organ Transplantation

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

scientific article published in Nature

Influenza hemagglutinin membrane anchor

article published in the Proceedings of the National Academy of Sciences of the United States of America

Inhibition of dendritic cell maturation by herpes simplex virus

scientific article published in October 1999

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

scientific article (publication date: September 2007)

Irreversible association of peptides with class II MHC molecules in living cells.

scientific article

Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex

scientific article

Kaposi's sarcoma cells express the macrophage-associated antigen mannose receptor and develop in peripheral blood cultures of Kaposi's sarcoma patients

scientific article published on March 1997

Kinetics and expression patterns of chemokine receptors in human CD4+ T lymphocytes primed by myeloid or plasmacytoid dendritic cells

scientific article published on 01 February 2003

Kinetics of MHC-antigen complex formation on antigen-presenting cells

scientific article published on June 1988

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

scientific article published on 01 October 2000

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

scientific article published on 13 October 2016

L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells.

scientific article published on 27 May 2007

Lack of fair play in the T cell response

scientific article published on 01 January 2002

Lead and follow: the dance of the dendritic cell and T cell

scientific article published on 01 December 2004

Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies

scientific article

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

scientific article

Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node.

scientific article published on March 2017

Maintenance of serological memory by polyclonal activation of human memory B cells.

scientific article published in December 2002

Mannose receptor mediated antigen uptake and presentation in human dendritic cells

scientific article published on 01 January 1997

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

scientific article published on 16 September 2020

Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

scientific article

Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes

scientific article published on 25 November 2002

Memory in disguise

scientific article published on 11 October 2011

Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines

scientific article published on 01 October 1995

Mobilizing dendritic cells for tolerance, priming, and chronic inflammation

scientific article published on February 1999

Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants

scientific article published on June 1995

Molecular Signatures of Immunity and Immunogenicity in Infection and Vaccination

scientific article published on 15 November 2017

Molecular analysis of human gamma/delta+ clones from thymus and peripheral blood

scientific article published on November 1989

Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone.

scientific article

Monoclonal Antibodies to Different Components of the Human Cytomegalovirus (HCMV) Pentamer gH/gL/pUL128L and Trimer gH/gL/gO as well as Antibodies Elicited during Primary HCMV Infection Prevent Epithelial Cell Syncytium Formation.

scientific article published on 27 April 2016

Monocytes join the dendritic cell family

scientific article published on 01 October 2010

Mouse pre-immunocytes as non-proliferating multipotent precursors of macrophages, interferon-producing cells, CD8alpha(+) and CD8alpha(-) dendritic cells

scientific article published on 01 November 2001

Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis

scientific article published on 16 June 2015

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

scientific article

Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells

scientific article published on November 2002

Organization of plasma membrane functional rafts upon T cell activation

scientific article

Origin, maturation and antigen presenting function of dendritic cells.

scientific article

Particle conformation regulates antibody access to a conserved GII.4 norovirus blockade epitope

scientific article

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

scientific article published in April 2012

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.

scientific article

Peptide partners call the tune

scientific article published in Nature

Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations

scientific article published on 19 February 2019

Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype

scientific article published on 14 March 2013

Phenotype and specificity of T cells in primary human cytomegalovirus infection during pregnancy: IL-7Rpos long-term memory phenotype is associated with protection from vertical transmission

scientific article published on 7 November 2017

Pillars Article: Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 1994. 179:11

scientific article published in February 2018

Pillars article: Antigen-specific interaction between T and B cells. 1985.

scientific article

Pillars article: two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 1999. 401: 708-712.

scientific article published in February 2014

Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes

scientific article

Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.

scientific article published in October 2000

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

article by Marina Cella et al published August 1999 in Nature Medicine

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

scientific article published on 06 June 2016

Polyclonal activation of human B lymphocytes in vitro by pokeweed mitogen: a simple technique for the simultaneous assessment of cell proliferation, generation of plasma cells, plaque-forming cells and immunoglobulin production

scientific article published on January 1978

Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies

scholarly article

Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility co ⬇️

scientific article published on March 1, 1992

Presentation of peptides by cultured monocytes or activated T cells allows specific priming of human cytotoxic T lymphocytes in vitro

Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways.

scientific article published on December 1989

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

scientific article

Professional presentation of antigen by activated human T cells

scholarly article by Vincenzo Barnaba et al published January 1994 in European Journal of Immunology

Progressive differentiation and selection of the fittest in the immune response

scientific article

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

scientific article published on 06 February 2003

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

scientific article

Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza

scientific article (publication date: May 2007)

Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells

scientific article published in May 2009

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

scientific article published on March 2017

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

scientific article

Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells

scientific article published on 01 January 2019

Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering

scientific article published on November 1997

Ralph M. Steinman 1943-2011.

scientific article

Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

scientific article published on 01 September 1998

Rapid development of broadly influenza neutralizing antibodies through redundant mutations

scientific article published on 5 October 2014

Rapid generation of a human monoclonal antibody to combat Middle East respiratory syndrome

scientific article published on 18 April 2016

Rational engineering of a human anti-dengue antibody through experimentally validated computational docking

scientific article

Re-expression of RAG-1 and RAG-2 genes and evidence for secondary rearrangements in human germinal center B lymphocytes

scientific article published on 01 November 1998

Recognition by Class II Alloreactive T Cells of Processed Determinants from Human Serum Proteins ⬇️

scientific article published on June 14, 1991

Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease

scientific article

Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

scientific article published on 8 May 2017

Regulation of T cell immunity by dendritic cells

scientific article

Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

scientific article

Regulation of peripheral T cell activation by calreticulin

scientific article

Restricted TCR repertoire and long-term persistence of donor-derived antigen-experienced CD4+ T cells in allogeneic bone marrow transplantation recipients.

scientific article published in December 1996

Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland

Role of B cells in TH cell responses in a mouse model of asthma.

scientific article published on 7 September 2017

Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility.

scientific article published in April 1993

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies

scientific article

SARS-like WIV1-CoV poised for human emergence

scientific article published on 14 March 2016

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

scientific article published on 03 July 2005

Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells

scientific article

Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells

scientific article

Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

scientific article

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

scientific article

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

scientific article published on May 1995

Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses

scientific article published in July 2015

Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates

scientific article published on 01 September 1996

Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases.

scientific article published in November 2006

Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature

scientific article published on 28 March 2021

Social network architecture of human immune cells unveiled by quantitative proteomics

scientific article published on 6 March 2017

Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation ⬇️

scientific article published on April 1, 1993

Somatic mutations and affinity maturation are impaired by excessive numbers of T follicular helper cells and restored by Treg cells or memory T cells

scientific article published on September 2015

Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells

scientific article published on 01 November 2001

Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection

scientific article

Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies

scientific article published on 28 December 2010

Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01

scientific article published on 22 October 2019

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structural and functional analysis of a potent sarbecovirus neutralizing antibody

scientific article published on 09 April 2020

Structural and molecular basis for Ebola virus neutralization by protective human antibodies

scientific article

Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge

scientific article

Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs

scientific article published on 09 July 2021

Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.

article by Yiwei Chen et al published April 2021 in Nature

Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes

scientific article published on 20 July 2016

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody

scientific article published on 13 July 2015

Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein

scientific article

Study on the immunogenicity of human class-II-restricted T-cell epitopes: processing constraints, degenerate binding, and promiscuous recognition.

scientific article

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

scientific article (publication date: June 2007)

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

scientific article published on February 1995

Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells

scientific article published on June 1999

Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.

scientific article

T cell activation by a bispecific anti-CD3/anti-major histocompatibility complex class I antibody

scientific article published on 01 June 1990

T cell activation determined by T cell receptor number and tunable thresholds.

scientific article

T cell costimulation by chemokine receptors

scientific article published on 10 April 2005

T cell fitness determined by signal strength

scientific article published on 17 March 2003

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines

scientific article

T cell priming by dendritic cells: thresholds for proliferation, differentiation and death and intraclonal functional diversification

scientific article published on 01 July 2002

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

scientific article published in Nature

T lymphocyte costimulation mediated by reorganization of membrane microdomains

scientific article

T-cell activation and the dynamic world of rafts

scientific article

T-cell trafficking in the central nervous system

scientific article published on July 2012

TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines

scientific article

Tackling influenza with broadly neutralizing antibodies

scientific article

The Antibody Response to Plasmodium falciparum: Cues for Vaccine Design and the Discovery of Receptor-Based Antibodies

scientific article published on 19 December 2018

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells

scientific article

The challenges of primary biliary cholangitis: What is new and what needs to be done

scientific article published on 20 September 2019

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells

scientific article published in March 2002

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

scientific article published on September 2010

The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics

scientific article

The instructive role of dendritic cells on T-cell responses

scientific article

The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

scientific article published on 01 September 1997

The role of aquaporins in dendritic cell macropinocytosis

scientific article published on February 2000

The role of chemokine receptors in directing traffic of naive, type 1 and type 2 T cells.

scientific article

The set of naturally processed peptides displayed by DR molecules is tuned by polymorphism of residue 86 ⬇️

scientific article published on February 1, 1993

The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells.

scientific article published in January 2008

Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected].

scientific article

Toll-like receptor stimulation as a third signal required for activation of human naive B cells.

scientific article

Toll-like receptors and innate immunity in B-cell activation and antibody responses

scientific article published on 12 April 2007

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

scientific article (publication date: 14 October 1999)

Understanding and making use of human memory B cells

scientific article published on June 2006

Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression

scientific article

Understanding the generation and function of memory T cell subsets

scientific article

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

scientific article published on 21 February 2019

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

scientific article published on 01 December 2020

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells.

scientific article published in December 1989

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.

scientific article published on 7 March 2018

Within-host evolution results in antigenically distinct GII.4 noroviruses

scientific article

kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire

scientific article published on March 1995

Paulina is supported by:

About Paulina

Help