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List of works by Atsushi Ogata

346 Clinical Effects of Tocilizumab, a Humanized Anti-interleukin-6 Receptor Antibody, on Patients with Autoimmune and Allergic Diseases.

scientific article published on 17 February 2012

572 Effect of Enzymatically Modified Isoquercitrin, a Flavonoid, on Symptoms of Japanese Cedar Pollinosis

A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab.

scientific article published on 12 July 2011

A new era for the treatment of inflammatory autoimmune diseases by interleukin-6 blockade strategy.

scientific article published on February 2014

A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.

scientific article published on January 2013

A randomized, double-blind, parallel-group, phase III study of shortening the dosing interval of subcutaneous tocilizumab monotherapy in patients with rheumatoid arthritis and an inadequate response to subcutaneous tocilizumab every other week: Resu

scientific article published on 16 June 2017

Adenovirus vector-based purging of multiple myeloma cells.

scientific article published on December 1998

Amelioration of small bowel injury by switching from nonselective nonsteroidal anti-inflammatory drugs to celecoxib in rheumatoid arthritis patients: a pilot study

scientific article published on 7 February 2014

Anti-estrogens induce apoptosis of multiple myeloma cells

scientific article published on 01 September 1998

Anti-interleukin-6 autoantibodies in rheumatic diseases. Increased frequency in the sera of patients with systemic sclerosis

scientific article published on 01 August 1992

Autoimmune myelofibrosis associated with systemic lupus erythematosus: a case report

scientific article published on 05 September 2019

Biliary interleukin 6 levels as indicators of hepatic allograft rejection in rats ⬇️

scientific article published on June 1, 1992

Blockade of mitogen-activated protein kinase cascade signaling in interleukin 6-independent multiple myeloma cells

scientific article published on 01 June 1997

Characterization of p16(INK4A) expression in multiple myeloma and plasma cell leukemia

scientific article published on 01 November 1997

Clinical significance of interleukin-6 gene expression in the bone marrow of patients with multiple myeloma

scientific article published on 01 October 1999

Clinical significance of vascular endothelial growth factor and hepatocyte growth factor in multiple myeloma

scientific article published on 01 March 2002

Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells

scientific article published on 01 November 1997

DNA damage in rheumatoid arthritis: an age-dependent increase in the lipid peroxidation-derived DNA adduct, heptanone-etheno-2'-deoxycytidine

scientific article published on 07 October 2013

Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism

scientific article published on 01 August 1997

Effect of graft-versus-host disease (GVHD) on host hematopoietic progenitor cells is mediated by Fas-Fas ligand interactions but this does not explain the effect of GVHD on donor cells

scientific article published on 01 October 1999

Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-β Therapy in Multiple Sclerosis ⬇️

scientific article published on April 9, 2012

Enhanced production of osteopontin in multiple myeloma: clinical and pathogenic implications

scientific article published on 01 October 2003

Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab

scientific article published on 18 February 2014

Gp130 in human myeloma/plasmacytoma

scientific article published on 01 January 1995

IL-18 gene polymorphisms affect IL-18 production capability by monocytes

scientific article published on 28 February 2006

IL-6 inhibitor for the treatment of rheumatoid arthritis: A comprehensive review

scientific article published on 03 January 2019

IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade.

scientific article published on September 1997

IgD multiple myeloma preceding the development of extensive extramedullary disease without medullary involvement

scientific article published in January 2000

Imatinib mesylate inhibited rat adjuvant arthritis and PDGF-dependent growth of synovial fibroblast via interference with the Akt signaling pathway.

scientific article published in July 2009

Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab

scientific article published on 26 October 2010

In vitro FK 506 kidney tubular cell toxicity

scientific article published on December 1, 1991

Increased serum interleukin-18 in a patient with systemic lupus erythematosus and T-cell large granular lymphocytic leukemia

scientific article published in January 2004

Inhibitory effect of all-trans retinoic acid on the growth of freshly isolated myeloma cells via interference with interleukin-6 signal transduction

scientific article published on 01 November 1994

Interleukin 6 levels in bile following liver transplantation

scientific article published on 01 February 1991

Interleukin-6 as a new indicator of inflammatory status: detection of serum levels of interleukin-6 and C-reactive protein after surgery

scientific article published on 01 February 1992

Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells

scientific article published on 01 January 1997

Interleukin-6 overcomes p21WAF1 upregulation and G1 growth arrest induced by dexamethasone and interferon-gamma in multiple myeloma cells

scientific article published on 01 July 1997

Interleukin-6 promotes multiple myeloma cell growth via phosphorylation of retinoblastoma protein.

scientific article

Levels of vascular endothelial growth factor and hepatocyte growth factor in sera of patients with rheumatic diseases.

scientific article published in June 2003

Long-Term Safety and Efficacy of Weekly Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis Who Had an Inadequate Response to Subcutaneous Tocilizumab Every Other Week: Results From the Open-Label Extension of the SHINOBI Study

article

MDM2 protein overexpression inhibits apoptosis of TF-1 granulocyte-macrophage colony-stimulating factor-dependent acute myeloblastic leukemia cells.

scientific article published on August 1998

MDM2 protein overexpression promotes proliferation and survival of multiple myeloma cells ⬇️

scientific article published on September 1, 1997

Minimal influence of tocilizumab on IFN-gamma synthesis by tuberculosis antigens

scientific article published on 07 November 2009

Minimal neonatal transfer of certolizumab pegol in a Japanese patient with rheumatoid arthritis

scientific article

Monoclonal antibodies in rheumatoid arthritis: comparative effectiveness of tocilizumab with tumor necrosis factor inhibitors

scientific article

Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone.

scientific article published on February 1999

Pathological role of interleukin-6 in psoriatic arthritis

scientific article published on 11 October 2012

Phase III study of the efficacy and safety of subcutaneous versus intravenous tocilizumab monotherapy in patients with rheumatoid arthritis.

scientific article

Psoriatic arthritis in two patients with an inadequate response to treatment with tocilizumab

scientific article published on 01 October 2011

Quantification of hardness, elasticity and viscosity of the skin of patients with systemic sclerosis using a novel sensing device (Vesmeter): a proposal for a new outcome measurement procedure.

scientific article

Rapid improvement of AA amyloidosis with humanised anti-interleukin 6 receptor antibody treatment

scientific article published on 01 July 2009

Regulation of cytokine expression by an autoreactive B cell clone derived from MRL/MP-lpr/lpr mice ⬇️

scientific article published on October 1, 1998

Retention of tocilizumab and anti-tumour necrosis factor drugs in the treatment of rheumatoid arthritis.

scientific article published on 7 March 2013

Role of CDK4 and p16INK4A in interleukin-6-mediated growth of multiple myeloma

scientific article published on 01 November 1997

Safety and Efficacy of Tocilizumab for the Treatment of Rheumatoid Arthritis ⬇️

scientific article published on March 5, 2012

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.

scientific article published on June 2015

Serum interleukin 6 as a predicator of the therapeutic effect and adverse reactions after transcatheter arterial embolization

scientific article published on 01 February 1995

Subcutaneous tocilizumab: recent advances for the treatment of rheumatoid arthritis

scientific article published on 01 June 2019

Successful therapy with steroid and cyclophosphamide pulse for CNS lupus and lupus myelitis

scientific article

Successful treatment of a patient with febrile, lobular panniculitis (Weber-Christian disease) with oral cyclosporin A: implications for pathogenesis and therapy.

scientific article published on July 1999

Successful treatment of reactive arthritis with a humanized anti-interleukin-6 receptor antibody, tocilizumab.

scientific article published in December 2009

Sustained response to tocilizumab, anti-interleukin-6 receptor antibody, in two patients with refractory relapsing polychondritis

scientific article published on 23 December 2008

Systemic production of interleukin-6 following acute inflammation

scientific article published on 01 December 1993

The 86-kD subunit of Ku autoantigen mediates homotypic and heterotypic adhesion of multiple myeloma cells ⬇️

scientific article published on March 15, 1998

The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis

scientific article

The development of a model for the homing of multiple myeloma cells to human bone marrow

scientific article published on 01 July 1997

The molecular mechanism in activation-induced cell death of an Ag-reactive B cell clone.

scientific article

The role of donor T cells for target organ injuries in acute and chronic graft-versus-host disease

scientific article published in July 2001

The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.

scientific article

Therapeutic effect of tocilizumab on two patients with polymyositis

scientific article published on 22 April 2011

Tocilizumab for the Treatment of Rheumatoid Arthritis and Other Systemic Autoimmune Diseases: Current Perspectives and Future Directions ⬇️

scientific article published on January 18, 2012

Treatment of a patient with remitting seronegative, symmetrical synovitis with pitting oedema with a humanized anti-interleukin-6 receptor antibody, tocilizumab

scientific article published on 11 December 2009

What kind of durometer is best suited for the assessment of skin disease in systemic sclerosis? Comment on the article by Kissin et al

scientific article published on 01 April 2008

[Advances in interleukin-6 therapy]

scientific article published on 01 April 1999

[Interleukin-6]

scientific article published on 01 August 1994

iTRAQ-based proteomic identification of leucine-rich alpha-2 glycoprotein as a novel inflammatory biomarker in autoimmune diseases

scientific article published on 22 October 2009

p16INK4A promotes differentiation and inhibits apoptosis of JKB acute lymphoblastic leukemia cells.

scientific article published on November 1997

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