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List of works by Mario Plebani

A manifesto for the future of laboratory medicine professionals

scientific article published on 13 November 2018

A note from the Editor in Chief regarding the Letter to the Editor "Great need for changes in higher education in Greece".

scientific article published on 4 April 2017

A real-world evidence-based approach to laboratory reorganization using e-Valuate benchmarking data

scientific article

Accreditation of medical laboratories in the European Union

scientific article

An approach for estimating measurement uncertainty in medical laboratories using data from long-term quality control and external quality assessment schemes.

scientific article

Analytical performance evaluation of the new GEM® Premier™ 5000 analyzer in comparison to the GEM® Premier™ 4000 and the RapidPoint® 405 systems

scientific article published on 15 August 2018

Analytical performance of 17 general chemistry analytes across countries and across manufacturers in the INPUtS project of EQA organizers in Italy, the Netherlands, Portugal, United Kingdom and Spain

scientific article

Analytical performances of a chemiluminescence immunoassay for SARS-CoV-2 IgM/IgG and antibody kinetics

scientific article published on 16 April 2020

Analytical quality: an unfinished journey

scientific article published on 13 September 2017

Antioxidant capacity in patients with type 2 diabetes: a preliminary investigation on gender-specific differences in an Italian population

scientific article

Appropriateness in programs for continuous quality improvement in clinical laboratories

scientific article

Appropriateness of cholesterol and triglycerides reporting checked by External Quality Assessment programs.

scientific article

Assessment and monitoring of agreement among professionals for morphological evaluation in compliance with International accreditation standard requirements

scientific article published on 25 November 2019

Assuring the quality of interpretative comments in clinical chemistry

scientific article published on 17 September 2016

Asymptomatic COVID-19 transmission: the importance of avoiding official miscommunication

scientific article published on 13 July 2020

Automated Blood Cell Counts

scientific article

Between Web search engines and artificial intelligence: what side is shown in laboratory tests?

scientific article published on 25 April 2020

Biochemical and genetic markers of erectile dysfunction

scientific article published on January 2012

Biological variation: back to basics

scientific article published on 01 February 2015

Biomarkers of acute kidney injury: a step forward

scientific article

Blood biomarkers in neurology: "a call to arms" for laboratory professionals

scientific article published on 01 September 2019

Borderline ovarian tumors and diagnostic dilemma of intraoperative diagnosis: could preoperative He4 assay and ROMA score assessment increase the frozen section accuracy? A multicenter case-control study

scientific article

Building a bridge to safe diagnosis in health care. The role of the clinical laboratory

scientific article published on 2 December 2015

C-peptide and insulin assays with the Mindray CL-2000i: Precision and comparability with different methods

scientific article published on 09 April 2019

CCLM Award for the Most Cited Paper Recently Published.

scientific article

CagA+ Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study

scientific article published in February 2007

Calcitonin measurement and immunoassay interference: a case report and literature review

scientific article published on 11 May 2016

Calcium-sensing receptor polymorphisms increase the risk of osteoporosis in ageing males

scientific article published on 10 October 2017

Cardiac biomarkers of acute coronary syndrome: from history to high-sensitive cardiac troponin

scientific article published on 17 February 2017

Cardiac troponins and physical exercise. It's time to make a point

scientific article published on January 2011

Cardiotoxic effects and myocardial injury: the search for a more precise definition of drug cardiotoxicity

scientific article published on 26 August 2020

ChatGPT: Angel or Demond? Critical thinking is still needed

scientific article published in 2023

Clinical Chemistry and Laboratory Medicine continues to shine brightly in the constellation of laboratory medicine

scientific article published on 01 August 2018

Clinical laboratory and SARS-CoV-2 infection: where do we stand?

scientific article published on 02 April 2020

Clinical laboratory: Factory or zero kilometer service?

scientific article published on 29 November 2019

Clinical laboratory: bigger is not always better

scientific article published on 01 June 2018

Clinical performance of cardiac Troponin I: A comparison between the POCT AQT90 FLEX and the Dimension Vista analyzer in an emergency setting

scientific article published on April 2017

Clinical significance of cytokine determination in synovial fluid

scientific article

Clinical usefulness of Glycated Albumin in the diagnosis of diabetes: Results from an Italian study.

scientific article published on 24 February 2018

Clinical utility of the (-2)proPSA and evaluation of the evidence: a systematic review.

scientific article

Clinical value and measurement of specific IgE.

scientific article

Cocaine in acute myocardial infarction

scientific article published on January 2010

Complete blood count at the ED: preanalytic variables for hemoglobin and leukocytes

scientific article published on 16 May 2015

Copeptin as a diagnostic and prognostic biomarker in patients admitted to Emergency Department with syncope, presyncope and vertiginous syndrome

scientific article published on 5 October 2017

Defective ADAMTS13 synthesis as a possible consequence of NASH in an obese patient with recurrent thrombotic thrombocytopenic purpura.

scientific article

Defining a roadmap for harmonizing quality indicators in Laboratory Medicine: a consensus statement on behalf of the IFCC Working Group "Laboratory Error and Patient Safety" and EFLM Task and Finish Group "Performance specifications for the extra-an

scientific article

Definition of the upper reference limit of glycated albumin in blood donors from Italy.

scientific article published on 6 June 2017

Developing GRADE outcome-based recommendations about diagnostic tests: a key role in laboratory medicine policies

scientific article published on 10 October 2015

Diabetes alert dogs: a narrative critical overview

scientific article published on 01 March 2019

Diagnosis of sphingolipidoses: a new simultaneous measurement of lysosphingolipids by LC-MS/MS.

scientific article

Diagnostic and prognostic role of presepsin in patients with cirrhosis and bacterial infection

scientific article published on 23 October 2020

Diagnostic test accuracy: a valuable tool for promoting quality and patient safety

scientific article published on 01 November 2018

Driving the route of laboratory medicine: a manifesto for the future

scientific article published on 19 February 2019

Effect of maternal smoking on breast milk interleukin-1alpha, beta-endorphin, and leptin concentrations and leptin concentrations

scientific article

Efficacy of weekly administration of cholecalciferol on parathyroid hormone in stable kidney-transplanted patients with CKD stage 1-3

scientific article published on 05 May 2020

Emerging role of monocytes and their intracellular calcium pattern in spondyloarthritis

scientific article published on 28 October 2019

Errors in laboratory medicine.

scientific article

Erythrocyte sedimentation rate is associated with severe coronavirus disease 2019 (COVID-19): a pooled analysis

scientific article published on 09 May 2020

Esophageal cancer management: preoperative CA19.9 and CEA serum levels may identify occult advanced adenocarcinoma

scientific article

Evaluation of an ELISA for SARS-CoV-2 antibody testing: clinical performances and correlation with plaque reduction neutralization titer

scientific article published on 08 August 2020

Evaluation of an improved small gauge needle for venipuncture in children with difficult venous access: Impact on sample quality, phlebotomist satisfaction and patient pain perception

scientific article published on 31 October 2019

Evaluation of reproducibility of the cTnT immunoassay using quality control samples

scientific article published on 22 April 2019

Evaluation of the hypochromic erythrocyte and reticulocyte hemoglobin content provided by the Sysmex XE-5000 analyzer in diagnosis of iron deficiency erythropoiesis

scientific article

Expression analysis and prognostic significance of human kallikrein 11 in prostate cancer

scientific article

External quality assessment programs in the context of ISO 15189 accreditation

scientific article published on 01 September 2018

Extra-analytical quality indicators - where to now?

scientific article

Extra-analytical quality indicators and laboratory performances.

scientific article published on 24 March 2017

Extra-analytical sources of uncertainty: which ones really matter?

scientific article published on 01 September 2019

Free light chains and heavy/light chains in monitoring POEMS patients

scientific article published on 01 June 2016

Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).

scientific article published in May 2006

Gender differences in endothelial progenitor cells and cardiovascular risk profile: the role of female estrogens

scientific article

Glypican-1 as a highly sensitive and specific pancreatic cancer biomarker

scientific article published on 19 September 2015

HCV core antigen comes of age: a new opportunity for the diagnosis of hepatitis C virus infection

scientific article published on 27 April 2018

Harmonization in laboratory medicine: Blowin' in the wind

scientific article published on 01 September 2018

Harmonization in laboratory medicine: more than clinical chemistry?

scientific article published on 2 November 2017

Harmonization of two hs-cTnI methods based on recalibration of measured quality control and clinical samples

scientific article published on 08 July 2020

Harmonization of units and reference intervals of plasma proteins: state of the art from an External Quality Assessment Scheme

scientific article published on 01 December 2018

Harmonization protocols for thyroid stimulating hormone (TSH) immunoassays: different approaches based on the consensus mean value.

scientific article published in February 2015

Healthcare is a giant with feet of clay

scientific article published on 01 June 2016

Hemolyzed specimens: a major challenge for emergency departments and clinical laboratories ⬇️

scientific article published on May 1, 2011

High level of oxysterols in neonatal cholestasis: a pitfall in analysis of biochemical markers for Niemann-Pick type C disease

scientific article published on 9 December 2015

High-sensitivity cardiac troponin I and T methods for the early detection of myocardial injury in patients on chemotherapy

scientific article published on 22 May 2020

Identifying risk in the use of tumor markers to improve patient safety.

scientific article published on 8 March 2016

IgA-Ab response to spike glycoprotein of SARS-CoV-2 in patients with COVID-19: A longitudinal study

scientific article published on 25 April 2020

Impaired Release of Vitamin D in Dysfunctional Adipose Tissue: New Cues on Vitamin D Supplementation in Obesity

scientific article published on 10 February 2017

Improving IBD diagnosis and monitoring by understanding preanalytical, analytical and biological fecal calprotectin variability

scientific article published on 01 October 2018

Improving diagnosis and reducing diagnostic errors: the next frontier of laboratory medicine

scientific article published on 01 July 2016

In Memoriam: Gérard Siest (1936-2016).

scientific article

Inflammation and pancreatic cancer: molecular and functional interactions between S100A8, S100A9, NT-S100A8 and TGFβ1

scientific article

Influence of patients' clinical features at intensive care unit admission on performance of cell cycle arrest biomarkers in predicting acute kidney injury

scientific article published on 28 September 2020

Influence of physiological dietary selenium supplementation on the natural course of autoimmune thyroiditis

scientific article

Insulin autoimmune syndrome (Hirata's disease) in an Italian patient: a case report and review of the literature

scientific article published on 16 September 2017

Interference in coagulation testing: focus on spurious hemolysis, icterus, and lipemia.

scientific article published on 10 December 2012

Interference of lipemia in samples for routine coagulation testing using a Sysmex CS-5100 coagulometer

scientific article published on 11 September 2019

Interpretative comments and reference ranges in EQA programs as a tool for improving laboratory appropriateness and effectiveness.

scientific article

Ischemia-modified albumin in the era of high-sensitivity troponin immunoassays: useful or hype?

scientific article published on 17 June 2013

Kinetics of highly sensitive troponin I and T after eccentric exercise

scientific article published on 13 August 2010

Laboratory abnormalities in children with novel coronavirus disease 2019

scientific article published on 16 March 2020

Laboratory abnormalities in patients with COVID-2019 infection

scientific article published on 03 March 2020

Laboratory testing in pharmacies

scientific article published on July 2010

Laboratory testing in the emergency department: an Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC) and Academy of Emergency Medicine and Care (AcEMC) consensus report.

scientific article published on 31 March 2017

Laboratory-related errors: you cannot manage what you don't measure. You manage what you know and measure

scientific article published on 01 November 2017

Less is more, but do not throw out the baby with the bathwater either!

scientific article published on 01 September 2014

Letter to the Editor in reply to Dayyani and Morgenstern's comment on the article "Identifying risk in the use of tumor markers to improve patient safety".

scientific article

Maldi-TOF analysis of portal sera of pancreatic cancer patients: identification of diabetogenic and antidiabetogenic peptides

scientific article

Managing transferability of laboratory data

scientific article

Mass spectrometry or immunoassay: est modus in rebus

scientific article

Measurement uncertainty in laboratory reports: A tool for improving the interpretation of test results

scientific article published on 13 March 2018

Measurement uncertainty: light in the shadows

scientific article published on 05 March 2020

Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)

scientific article

Molecular diagnostics at the times of SARS-CoV-2 outbreak

scientific article published on 28 April 2020

New insights on the analytical performances for detecting and quantifying monoclonal proteins

scientific article published on 01 March 2020

New issues on measurement of B-type natriuretic peptides

scientific article published on 15 August 2017

Norbert Tietz, 13th November 1926-23rd May 2018

scientific article published on 01 July 2018

One disease, different features: COVID-19 laboratory and radiological findings in three Italian patients

scientific article published on 02 April 2020

Opportunities and drawbacks of nonstandard body fluid analysis

scientific article

Osteocalcin and Sex Hormone Binding Globulin Compete on a Specific Binding Site of GPRC6A.

scientific article published on 27 September 2016

Overweight - obesity is associated with decreased vitamin K2 levels in hemodialysis patients

scientific article published on 08 May 2020

PSA-based, prostate cancer risk on-line calculators: no such thing as a crystal ball?

scientific article published on 01 November 2018

Pancreatic cancer alters human CD4+ T lymphocyte function: a piece in the immune evasion puzzle

scientific article

Parathormone stability in hemodialyzed patients and healthy subjects: comparison on non-centrifuged EDTA and serum samples with second- and third-generation assays

scientific article published on 18 January 2017

Patient and Sample Identification. Out of the Maze?

scientific article

Patient safety and quality in laboratory and hemostasis testing: a renewed loop?

scientific article published on 02 June 2012

Peptidomic and proteomic analysis of stool for diagnosing IBD and deciphering disease pathogenesis

scientific article published on 27 March 2020

Percentile transformation and recalibration functions allow harmonization of thyroid-stimulating hormone (TSH) immunoassay results

scientific article published on 13 January 2020

Performance criteria and quality indicators for the post-analytical phase.

scientific article published on 10 December 2015

Performance evaluation of 14 specific proteins measurement checked by an External Quality Assessment Scheme

scientific article published on 10 December 2019

Performance evaluation of ImmunoCAP® ISAC 112: a multi-site study.

scientific article published on 7 November 2016

Performance specifications for the extra-analytical phases of laboratory testing: Why and how.

scientific article

Performance specifications of critical results management.

scientific article published on 25 May 2017

Pilot study on harmonization of cardiac troponin I immunoassays using patients and quality control plasma samples. On behalf of the Italian Section of the European Ligand Assay Society (ELAS) and of the Study Group on Cardiovascular Biomarkers of th

scientific article published on 25 February 2016

Platelet response to Helicobacter pylori eradication therapy in adult chronic idiopathic thrombocytopenic purpura seems to be related to the presence of anticytotoxin-associated gene A antibodies

scientific article

Potential preanalytical and analytical vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19)

scientific article published on 16 March 2020

Pre-analytical quality indicators in laboratory medicine: Performance of laboratories participating in the IFCC working group "Laboratory Errors and Patient Safety" project

scientific article published on 08 July 2019

Preanalytical challenges - time for solutions

scientific article published on 01 June 2019

Presence of anti-ADAMTS13 antibodies in obesity.

scientific article

Presepsin in risk stratification of SARS-CoV-2 patients

scientific article published on 22 April 2020

Procalcitonin (PCT)-guided antibiotic stewardship: an international experts consensus on optimized clinical use

scientific article published on 01 August 2019

Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis

scientific article published on 04 March 2020

Procalcitonin-guided antibiotic therapy: an expert consensus

scientific article published on 01 July 2018

Proficiency testing project for brain natriuretic peptide (BNP) and the N-terminal part of the propeptide of BNP (NT-proBNP) immunoassays: the CardioOrmocheck study.

scientific article published in January 2009

Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation.

scientific article published in September 2013

Prospective validation of an automated chemiluminescence-based assay of renin and aldosterone for the work-up of arterial hypertension.

scientific article published on 29 January 2016

Prostate-specific antigen, prostate cancer, and disorders of hemostasis

scientific article published on October 2009

Proteomic analysis of venous thromboembolism

scientific article published on April 2010

Putative pancreatic cancer-associated diabetogenic factor: 2030 MW peptide

scientific article

Quality Indicators in Laboratory Medicine: from theory to practice. Preliminary data from the IFCC Working Group Project "Laboratory Errors and Patient Safety".

scientific article

Quality Indicators in Laboratory Medicine: the status of the progress of IFCC Working Group "Laboratory Errors and Patient Safety" project.

scientific article published on 19 December 2016

Quality and future of clinical laboratories: the Vico's whole cyclical theory of the recurring cycles

scientific article published on 10 February 2018

Quality controls for serology: an unfinished agenda

scientific article published on 10 April 2020

Quality of plasma samples and BD Vacutainer Barricor tubes: Effects of centrifugation

scientific article published on 10 May 2018

Quality performance of laboratory testing in pharmacies: a collaborative evaluation

scientific article published on 19 May 2016

Recommendations for the clinical use of cardiac natriuretic peptides

scientific article

Reference intervals for hemoglobin A1c in pregnant women: data from an Italian multicenter study

scientific article

Reflex TSH strategy: the good, the bad and the ugly

scientific article published on 01 December 2019

Reporting altered test results in hemolyzed samples: is the cure worse than the disease?

scientific article published on 16 February 2017

SARS-CoV-2 RNA identification in nasopharyngeal swabs: issues in pre-analytics

scientific article published on 22 June 2020

SARS-CoV-2 antibody performances: we need better criteria

scientific article published on 25 September 2020

SARS-CoV-2 serosurvey in health care workers of the Veneto Region

scientific article published on 26 August 2020

Sample collections from healthy volunteers for biological variation estimates' update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine

scientific article

Sensitive cardiac troponin T assay

scientific article published in April 2010

SerpinB3 Promotes Pro-fibrogenic Responses in Activated Hepatic Stellate Cells.

scientific article

Serum YKL-40 following resection for cerebral glioblastoma

scientific article published in April 2012

Serum or plasma? An old question looking for new answers

scientific article published on 01 January 2020

Short-term biological variation and diurnal rhythm of cardiac troponin I (Access hs-TnI) in healthy subjects

scientific article published on 05 February 2020

Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors

scientific article

State of the art of BNP and NT-proBNP immunoassays: the CardioOrmoCheck study.

scientific article

System-related and cognitive errors in laboratory medicine

scientific article published on 01 November 2018

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

scientific article published on 27 April 2015

Targeting errors in microbiology: the case of the Gram stain

scientific article

Technological advances in the hemostasis laboratory

scientific article published on 17 January 2014

The 99th percentile of reference population for cTnI and cTnT assay: methodology, pathophysiology and clinical implications.

scientific article

The Choosing Wisely campaign - don't throw the baby out with the bathwater.

scientific article

The Italian External Quality Assessment (EQA) program on urinary sediment: results of the period 2012-2015.

scientific article published on 17 October 2015

The Model List of Essential In Vitro Diagnostics: nuisance or opportunity?

scientific article published on 01 August 2019

The Theranos saga and the consequences

scientific article published on 01 August 2018

The changing face of hemostasis testing in modern laboratories: consolidation, automation, and beyond

scientific article published on 19 February 2015

The circulating miRNAs as diagnostic and prognostic markers

scientific article published on 01 June 2019

The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks

scientific article published on 19 March 2020

The future of laboratory medicine: Navigating between technology and professionalism

scientific article published on 26 July 2019

The measurement of cardiac troponins in patients undergoing major orthopaedic surgery

scientific article

The quality indicator paradox

scientific article published on 7 December 2015

The rs2274911 polymorphism in GPRC6A gene is associated with insulin resistance in normal weight and obese subjects.

scientific article published in October 2016

The silk road to total quality in Laboratory Medicine

scientific article published on 01 May 2019

The standardization of the urine albumin assays: no longer deferrable

scientific article published on 19 September 2015

The syndrome of the "obsessive-compulsory scientist": a new mental disorder?

scientific article published in August 2013

The ten commandments of laboratory testing for emergency physicians

scientific article published on 01 February 2014

The use of extra-analytical phase quality indicators by clinical laboratories: the results of an international survey.

scientific article published on 27 September 2016

Theranos phenomenon - Part 5: Theranos' presentation at the American Association for Clinical Chemistry Annual Conference 2016.

scientific article published on 30 August 2016

Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis

scientific article published on 13 March 2020

Total testing process: roots and state-of-the-art

scientific article published on 01 January 2020

Towards a new paradigm in laboratory medicine: the five rights

scientific article

Towards the rational utilization of SARS-CoV-2 serological tests in clinical practice

scientific article published on 03 July 2020

Traceable machine learning real-time quality control based on patient data

scientific article published in 2022

Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer.

scientific article

Two-center comparison of 10 fully-automated commercial procalcitonin (PCT) immunoassays

scientific article published on 01 December 2019

Understanding and managing interferences in clinical laboratory assays: the role of laboratory professionals

scientific article published on 01 February 2020

Urine chloride self-measurement to monitor sodium chloride intake in patients with chronic kidney disease

scientific article published on 01 July 2019

Usefulness of MALDI-TOF/MS identification of low-MW fragments in sera for the differential diagnosis of pancreatic cancer

scientific article

Verification of examination procedures in clinical laboratory for imprecision, trueness and diagnostic accuracy according to ISO 15189:2012: a pragmatic approach

scientific article

Vitamin D Prevents Pancreatic Cancer-Induced Apoptosis Signaling of Inflammatory Cells

scientific article published on 15 July 2020

Vitamin K plasma levels determination in human health.

scientific article

Vitamins B2 and B6 and genetic polymorphisms related to one-carbon metabolism as risk factors for gastric adenocarcinoma in the European prospective investigation into cancer and nutrition

scientific article published in January 2010

What information on measurement uncertainty should be communicated to clinicians, and how?

scientific article published on 2 February 2018

Why harmonization is essential to realize the manifesto for the future of laboratory medicine

scientific article published on 03 April 2019

Widespread increase in myeloid calcifying cells contributes to ectopic vascular calcification in type 2 diabetes

scientific article published on 10 March 2011

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