List of works by Larissa Fabritz

191 Advancement of Optical Mapping through Automated Algorithms and Second Generation CMOS Detectors to Reveal Murine Atrial Activation Patterns and Regional Variation of Action Potential Duration

A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity

scientific article

A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference

scientific article

Age- and Training-Dependent Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Heterozygous Plakoglobin-Deficient Mice

article

Amiodarone-induced postrepolarization refractoriness suppresses induction of ventricular fibrillation

scientific article published in April 2003

An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane action potentials

scientific article published on 15 August 2014

An introduction to murine models of atrial fibrillation

scientific article published on 03 August 2012

An ultrasound view on the substrate for incident and recurrent atrial fibrillation in heart failure patients

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

scientific article published in 2022

Anterior T-Wave Inversion Does Not Convey Short-Term Sudden Death Risk

Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model

article

Arrhythmogenic right ventricular cardiomyopathy: an update on pathophysiology, genetics, diagnosis, and risk stratification

scientific article published on 26 September 2012

Atrial Arrhythmias in long-QT syndrome under daily life conditions: a nested case control study

scientific article published on 27 October 2008

Autonomic modulation and antiarrhythmic therapy in a model of long QT syndrome type 3

scientific article

Ca/calmodulin kinase II differentially modulates potassium currents

scientific article published on 17 April 2009

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

scientific article

Can T-type calcium channels make a change of heart after myocardial infarction? Fiction or fact, and for better or for worse?

scientific article published on 17 June 2011

Can biomarkers balance stroke and bleeding risk?

scientific article published in The Lancet

Can preload-reducing therapy prevent disease progression in arrhythmogenic right ventricular cardiomyopathy? Experimental evidence and concept for a clinical trial

scientific article published on 27 August 2012

Cardiac Optogenetics and Optical Mapping - Overcoming Spectral Congestion in All-Optical Cardiac Electrophysiology

article

Cardiac overexpression of the human 5-HT4 receptor in mice.

scientific article published on 16 July 2010

Cardiac pacemaker function of HCN4 channels in mice is confined to embryonic development and requires cyclic AMP.

scientific article

Cell-based therapy of the failing heart: a need to connect for proper electrical and contractile function

Clinical Potential of Targeting Fibroblast Growth Factor-23 and αKlotho in the Treatment of Uremic Cardiomyopathy

scientific article published on 26 March 2020

Computer analysis of monophasic action potentials: manual validation and clinically pertinent applications.

scientific article

Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging

scientific article

Data-driven discovery and validation of circulating blood-based biomarkers associated with prevalent atrial fibrillation

scientific article published on 01 April 2019

Development and external validation of predictive models for prevalent and recurrent atrial fibrillation: a protocol for the analysis of the CATCH ME combined dataset

scientific article published on 21 May 2019

Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation

scientific article published on 26 August 2021

Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes

scientific article published in October 2002

Drug-induced torsades de pointes — A form of mechano-electric feedback?

scientific article published in November 2007

Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference

scientific article published in 2022

Effects of genetic background, sex, and age on murine atrial electrophysiology

scientific article published on 01 June 2021

ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology

scientific article published in Scientific Reports

Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank

scientific article published in 2022

Enhanced activity of the myocardial Na+/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice.

scientific article

European Society of Cardiology smartphone and tablet applications for patients with atrial fibrillation and their health care providers

scientific article published on 10 October 2017

Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment.

scientific article published on 24 December 2015

Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.

scientific article published on 6 February 2003

First report on an inotropic peptide activating tetrodotoxin-sensitive, "neuronal" sodium currents in the heart

scientific article published on 25 November 2014

Flecainide acetate for the treatment of atrial and ventricular arrhythmias

scientific article published on 07 January 2013

G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased connexin43 expression and arteriogenesis

scientific article

Gene construction, expression and functional testing of an inotropic peptide from the venom of the black scorpion Hottentotta judaicus

scientific article published on 22 October 2012

Gene dose-dependent atrial arrhythmias, heart block, and brady-cardiomyopathy in mice overexpressing A(3) adenosine receptors

scientific article published on June 2004

Heart-directed expression of a human cardiac isoform of cAMP-response element modulator in transgenic mice

scientific article published on 29 November 2004

High-Density Lipoprotein Shortens the Ventricular Action Potential

High-Throughput Analysis of Optical Mapping Data Using ElectroMap

scientific article published on 04 June 2019

Hypervolemic hypertension in mice with systemic inactivation of the (floxed) guanylyl cyclase-A gene by alphaMHC-Cre-mediated recombination

scientific article

Impaired relaxation in transgenic mice overexpressing junctin.

scientific article published in August 2003

Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality

scientific article published on 08 August 2008

Insights into sick sinus syndrome from an inducible mouse model

scientific article published on 30 December 2010

Integrating new approaches to atrial fibrillation management: the 6th AFNET/EHRA Consensus Conference

scientific article published on 2 January 2018

Ivabradine in patients with inappropriate sinus tachycardia

scientific article

Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability

scientific article published on 19 August 2010

Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

scientific article

Load-Reducing Therapy Prevents Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Plakoglobin-Deficient Mice

article

Local Atrial Natriuretic Peptide Signaling Prevents Hypertensive Cardiac Hypertrophy in Endothelial Nitric-oxide Synthase-deficient Mice

scientific article published on 26 March 2005

Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice

scientific article published on 24 July 2017

Minimally invasive closed-chest ultrasound-guided substance delivery into the pericardial space in mice

scientific article published on 19 December 2012

Modulation of cardiac contractility by serine/threonine protein phosphatase type 5 ⬇️

scientific article published on September 28, 2010

Of hammers and screws: renin-angiotensin-aldosterone system inhibition to prevent atrial fibrillation in patients with hypertension

Optical mapping design for murine atrial electrophysiology

article published in 2015

Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice

scientific article published on 16 November 2011

PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

scientific article published on October 2016

PITX2-dependent gene regulation in atrial fibrillation and rhythm control

scientific article

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

article

Phytanic acid accumulation is associated with conduction delay and sudden cardiac death in sterol carrier protein-2/sterol carrier protein-x deficient mice

scientific article published in November 2004

Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice

scientific journal article

Postrepolarization refractoriness: A mechanism in need for a molecule?

Preclinical testing of drug-induced proarrhythmia: value of transgenic models.

scientific article published on October 2007

Predicting recurrent atrial fibrillation after catheter ablation: a systematic review of prognostic models

scientific article published on 30 March 2020

Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca 2+ exchanger overexpression: whole heart and cellular mechanisms

scientific article published on 11 February 2012

Prognostic models for predicting incident or recurrent atrial fibrillation: protocol for a systematic review

scientific article published on 28 August 2019

Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia

scientific article

Reduced arrhythmogenicity of biphasic versus monophasic T-wave shocks. Implications for defibrillation efficacy.

scientific article

Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation

scientific article published on 20 August 2020

Regional, age-dependent, and genotype-dependent differences in ventricular action potential duration and activation time in 410 Langendorff-perfused mouse hearts

scientific article published on 14 March 2009

Selective atrial profibrotic signalling in mice and man.

scientific article published in September 2013

Sex differences in catheter ablation of atrial fibrillation: results from AXAFA-AFNET 5

scientific article published on 06 March 2020

Shock-induced dispersion of ventricular repolarization: implications for the induction of ventricular fibrillation and the upper limit of vulnerability

scientific article published in September 1997

Spontaneous Brugada electrocardiogram patterns are rare in the German general population: results from the KORA study

scientific article published on 04 August 2009

Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin

Survivin determines cardiac function by controlling total cardiomyocyte number

scientific journal article

Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue

scientific article

Temporal irregularity quantification and mapping of optical action potentials using wave morphology similarity

scientific article published on 30 December 2019

The Biomarkers NT-proBNP and CA-125 are Elevated in Patients with Idiopathic Atrial Fibrillation.

scientific article published on 31 December 2018

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results

scientific article published on 12 September 2015

The RACE-3 is on: double-locking sinus rhythm by upstream and downstream therapy

scientific article published on 7 February 2018

The power of P in the elderly: Small biphasic wave, big impact

scientific article published in March 2016

To the Editor--Propranolol, a β-adrenoreceptor blocker, prevents arrhythmias also by its sodium channel blocking effect

scientific article published on 19 December 2013

Triadin is a critical determinant of cellular Ca cycling and contractility in the heart.

scientific article

Universal cardiac induction of human pluripotent stem cells in two and three-dimensional formats: implications for in vitro maturation.

scientific article published on May 2015

Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide

scientific article

Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.

scientific article published on 31 May 2012

Ventricular arrhythmias, increased cardiac calmodulin kinase II expression, and altered repolarization kinetics in ANP receptor deficient mice

scientific article

Vorhofflimmern: Molekularbiologische Grundlagen

scientific article published on 01 June 2002

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