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List of works by Jorge Manzanares

3-Methoxy-4-hydroxyphenylethyleneglycol concentrations in discrete hypothalamic nuclei reflect the activity of noradrenergic neurons ⬇️

scientific article published on September 13, 1991

Activation of tuberohypophysial dopamine neurons following intracerebroventricular administration of the selective kappa opioid receptor antagonist nor-binaltorphimine ⬇️

scientific article published on January 1, 1991

Activation of tuberoinfundibular and tuberohypophysial dopamine neurons following intracerebroventricular administration of bombesin ⬇️

scientific article published on November 22, 1991

Alterations in Gene and Protein Expression of Cannabinoid CB2 and GPR55 Receptors in the Dorsolateral Prefrontal Cortex of Suicide Victims.

scientific article published on 12 February 2018

Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors.

scientific article

Cannabidiol Modulates Behavioural and Gene Expression Alterations Induced by Spontaneous Cocaine Withdrawal

scientific article published on 23 November 2020

Cannabidiol as a Potential Treatment for Anxiety Disorders

scientific article

Cannabidiol reduces ethanol consumption, motivation and relapse in mice

scientific article published on 13 February 2017

Cannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal.

scientific article published on 6 April 2018

Cannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress

article

Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson's Disease

scientific article

Cannabinoid/opioid crosstalk in the central nervous system

scientific article

Changes in prodynorphin and POMC gene expression in several brain regions of rat fetuses prenatally exposed to Delta(9)-tetrahydrocannabinol

scientific article

Characterization of opioid receptor-mediated regulation of incertohypothalamic dopamine neurons: lack of evidence for a role of 5-hydroxytryptaminergic neurons in mediating the stimulatory effects of morphine

scientific article published on September 18, 1992

Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors

scientific article

Decreased GABAA and GABAB receptor functional activity in cannabinoid CB1 receptor knockout mice

scientific article published on 8 February 2010

Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist.

scientific article

Effect of beta-pyridyl-carbinol on platelet aggregation ⬇️

scientific article published on March 15, 1988

Effects of cannabidiol plus naltrexone on motivation and ethanol consumption

scientific article published on 01 July 2018

Effects of immunoneutralization of dynorphin1-17 and dynorphin1-8 on the activity of central dopaminergic neurons in the male rat

scientific article published on August 7, 1992

Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects

scientific article

Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation

Extinction of cocaine self-administration produces alterations in corticotropin releasing factor gene expression in the paraventricular nucleus of the hypothalamus ⬇️

scientific article published on October 7, 2003

Gender differences in the effects of cannabidiol on ethanol binge drinking in mice

scientific article published on 09 May 2019

Gene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims

scientific article published on 5 December 2012

Identification of endocannabinoids and cannabinoid CB(1) receptor mRNA in the pituitary gland

scientific article

Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors

scientific article published in June 2004

Increased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission

scientific article published on 4 October 2011

Increased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors.

scientific article published on 5 May 2009

Kappa opioid receptor-mediated regulation of prolactin and alpha-melanocyte-stimulating hormone secretion in male and female rats

scientific article

Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice

scientific article published in October 2005

Neurochemical evidence that estrogen-induced suppression of kappa-opioid-receptor-mediated regulation of tuberoinfundibular dopaminergic neurons is prolactin-independent

scientific article

Neurotransmitter amino acid in cerebrospinal fluid of patients with dementia with Lewy bodies

scientific article published on 10 September 2004

Noradrenergic innervation to the VMN or MPN is not necessary for lordosis ⬇️

scientific article published on July 1, 1991

Opioid and Cannabinoid Systems as Therapeutic Targets for the Treatment of Alcohol Dependence: From Animal Models to Clinical Practice

Opioid and cannabinoid receptor-mediated regulation of the increase in adrenocorticotropin hormone and corticosterone plasma concentrations induced by central administration of delta(9)-tetrahydrocannabinol in rats

scientific article published in August 1999

Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice ⬇️

scientific article published on September 13, 2010

Plasmatic somatostatin as a marker of positive symptoms of schizophrenia

scientific article published on March 1, 1992

Prenatal Delta(9)-tetrahydrocannabinol exposure modifies proenkephalin gene expression in the fetal rat brain: sex-dependent differences

scientific article

Prodynorphin gene deletion increased anxiety-like behaviours, impaired the anxiolytic effect of bromazepam and altered GABAA receptor subunits gene expression in the amygdala

scientific article

Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice

scientific article

Repeated administration of delta9-tetrahydrocannabinol produces a differential time related responsiveness on proenkephalin, proopiomelanocortin and corticotropin releasing factor gene expression in the hypothalamus and pituitary gland of the rat

scientific article

Repeated administration with Delta9-tetrahydrocannabinol regulates mu-opioid receptor density in the rat brain

scientific article

Role of endocannabinoid system in mental diseases

scientific article published in January 2004

Role of gonadal steroids in the corticotropin-releasing hormone and proopiomelanocortin gene expression response to Delta(9)-tetrahydrocannabinol in the hypothalamus of the rat.

scientific article published in September 2001

Role of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes

scientific article published on July 2006

Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland

scientific article

Sexual differences in kappa opioid receptor-mediated regulation of tuberoinfundibular dopaminergic neurons

scientific article published on March 1, 1992

Sexual differences in the activity of periventricular-hypophysial dopaminergic neurons in rats

scientific article published on January 1, 1992

Sexual differences in the stimulatory effects of bombesin on tuberoinfundibular dopaminergic neurons

scientific article published on December 11, 1992

Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors

scientific article

Time course of opioid and cannabinoid gene transcription alterations induced by repeated administration with fluoxetine in the rat brain

scientific article published in October 2005

Time dependent alterations on tyrosine hydroxylase, opioid and cannabinoid CB1 receptor gene expressions after acute ethanol administration in the rat brain

scientific article

Time-dependent differences of repeated administration with Delta9-tetrahydrocannabinol in proenkephalin and cannabinoid receptor gene expression and G-protein activation by mu-opioid and CB1-cannabinoid receptors in the caudate-putamen

scientific article

delta-Opioid receptor-mediated regulation of central dopaminergic neurons in the rat.

scientific article

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