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List of works by Lorenz von Seidlein

"Nine Dimensions": A multidisciplinary approach for community engagement in a complex postwar border region as part of the targeted malaria elimination in Karen/Kayin State, Myanmar

scientific article published on 01 January 2018

A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multi Drug Resistant Falciparum Malaria in Cambodian Villages

scientific article

A comparison of disease caused by Shigella and Campylobacter species: 24 months community based surveillance in 4 slums of Karachi, Pakistan ⬇️

scientific article published on February 1, 2011

A cost function analysis of shigellosis in Thailand

scientific article published in March 2008

A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995)

scientific article

A multi-level spatial analysis of clinical malaria and subclinical Plasmodium infections in Pailin Province, Cambodia

scientific article

A multicentre study of Shigella diarrhoea in six Asian countries: disease burden, clinical manifestations, and microbiology

scientific article (publication date: September 2006)

A randomized, placebo-controlled trial of the bivalent killed, whole-cell, oral cholera vaccine in adults and children in a cholera endemic area in Kolkata, India

scientific article

A study of typhoid fever in five Asian countries: disease burden and implications for controls

scientific article

Acceptability and accessibility of a Shigellosis vaccine in Nha Trang city of Viet Nam.

scientific article

Adults' perceived prevalence of enteric fever predicts laboratory-validated incidence of typhoid fever in children

scientific article

Affordable house designs to improve health in rural Africa: a field study from northeastern Tanzania

article

Airflow attenuation and bed net utilization: observations from Africa and Asia

scientific article

Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine

scientific article

Antimalarial use during pregnancy and its effect on birthweight

scientific article published in September 2002

Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones

scientific article

Artemisinin resistance: current status and scenarios for containment

scientific article

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

scientific article published on 13 November 2010

Artesunate-mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial

scientific article published on 18 November 2015

Assessment and comparative analysis of a rapid diagnostic test (Tubex®) for the diagnosis of typhoid fever among hospitalized children in rural Tanzania

scientific article

Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

scientific article

Association between Subclinical Malaria Infection and Inflammatory Host Response in a Pre-Elimination Setting

scientific article

Asymptomatic Natural Human Infections With the Simian Malaria Parasites Plasmodium cynomolgi and Plasmodium knowlesi

scholarly article by Mallika Imwong et al published 8 October 2018 in Journal of Infectious Diseases

Asymptomatic Plasmodium infections in 18 villages of southern Savannakhet Province, Lao PDR (Laos)

scientific article

Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants?

scientific article published on 3 April 2008

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group

scientific article

Challenges to replace ACT as first-line drug

scientific article published on 24 July 2017

Characteristics of a pandemic clone of O3 : K6 and O4 : K68 Vibrio parahaemolyticus isolated in Beira, Mozambique.

scientific article

Chemotherapeutic strategies for reducing transmission of Plasmodium vivax malaria

scientific article published on January 2012

Cholera outbreak in Yemen

scientific article published on November 2017

Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique in 2005.

scientific article published on 10 December 2009

Climate variability and the outbreaks of cholera in Zanzibar, East Africa: a time series analysis

scientific article

Clinical and epidemiological features of typhoid fever in Pemba, Zanzibar: assessment of the performance of the WHO case definitions

scientific article

Clinical, epidemiological, and socioeconomic analysis of an outbreak of Vibrio parahaemolyticus in Khanh Hoa Province, Vietnam.

scientific article

Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers

scientific article published on 15 August 2019

Community engagement and population coverage in mass anti-malarial administrations: a systematic literature review

scientific article

Community engagement and the social context of targeted malaria treatment: a qualitative study in Kayin (Karen) State, Myanmar

scientific article published on 14 February 2017

Community engagement for the rapid elimination of malaria: the case of Kayin State, Myanmar

scientific article published on 28 July 2017

Community engagement, social context and coverage of mass anti-malarial administration: Comparative findings from multi-site research in the Greater Mekong sub-Region

scientific article published on 25 March 2019

Community participation during two mass anti-malarial administrations in Cambodia: lessons from a joint workshop

scientific article published on 27 January 2018

Community perceptions of targeted anti-malarial mass drug administrations in two provinces in Vietnam: a quantitative survey

scientific article published on 06 January 2017

Community-acquired bacterial bloodstream infections in developing countries in south and southeast Asia: a systematic review

scientific article

Comparison of Rapid Diagnostic Tests for the Detection of Plasmodium vivax Malaria in South Korea ⬇️

scientific article published on May 7, 2013

Comparison of Three Screening Test Kits for G6PD Enzyme Deficiency: Implications for Its Use in the Radical Cure of Vivax Malaria in Remote and Resource-Poor Areas in the Philippines

scientific article published on 5 February 2016

Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial

scientific article

Comparison of glucose-6 phosphate dehydrogenase status by fluorescent spot test and rapid diagnostic test in Lao PDR and Cambodia.

scientific article

Comparisons of predictors for typhoid and paratyphoid fever in Kolkata, India

scientific article

Consecutive outbreaks of Vibrio cholerae O139 and V. cholerae O1 cholera in a fishing village near Karachi, Pakistan

scientific article published on 26 January 2006

Considerations for Oral Cholera Vaccine Use during Outbreak after Earthquake in Haiti, 2010–2011 ⬇️

scholarly article by Lorenz von Seidlein & Jacqueline L Deen published July 2012 in Emerging Infectious Diseases

Correction to: The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

scientific article published on 21 January 2020

Correction: Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children.

scientific article

Correction: The burden of diarrhoea, shigellosis, and cholera in North Jakarta, Indonesia: findings from 24 months surveillance.

scientific article published on 26 January 2007

Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa

scientific article published on 28 April 2011

Decreasing incidence of severe malaria and community-acquired bacteraemia among hospitalized children in Muheza, north-eastern Tanzania, 2006-2010 ⬇️

scientific article (publication date: 27 October 2011)

Defining falciparum-malaria-attributable severe febrile illness in moderate-to-high transmission settings on the basis of plasma PfHRP2 concentration

scientific article published on 7 November 2012

Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement

scientific article published in 2012

Diagnosis, clinical presentation, and in-hospital mortality of severe malaria in HIV-coinfected children and adults in Mozambique

scientific article

Diarrhoea episodes and treatment-seeking behaviour in a slum area of North Jakarta, Indonesia.

scientific article

Differences in perception of dysentery and enteric fever and willingness to receive vaccines among rural residents in China

scientific article

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

scientific article

Effectiveness of an oral cholera vaccine in Zanzibar: findings from a mass vaccination campaign and observational cohort study

scientific article published on 4 September 2012

Effectiveness of mass oral cholera vaccination in Beira, Mozambique

scientific article

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5-17 months in Kenya and Tanzania: a randomised controlled trial

scientific article published on 13 January 2011

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

scientific article

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa

scientific article published on 22 February 2017

Enhanced disease surveillance through private health care sector cooperation in Karachi, Pakistan: experience from a vaccine trial

scientific article published on January 2006

Enteric fever burden in North Jakarta, Indonesia: a prospective, community-based study

scientific article

Estimating the burden of shigellosis in Thailand: 36-month population-based surveillance study

scientific article published on October 2005

Evaluation of a PfHRP2 and a pLDH-based rapid diagnostic test for the diagnosis of severe malaria in 2 populations of African children

scientific article

Evaluation of a dried blood spot HIV-1 RNA program for early infant diagnosis and viral load monitoring at rural and remote healthcare facilities

scientific article

Evaluation of a rapid dipstick (Crystal VC) for the diagnosis of cholera in Zanzibar and a comparison with previous studies

scientific article

Evaluation of new-generation serologic tests for the diagnosis of typhoid fever: data from a community-based surveillance in Calcutta, India

scientific article

Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies

scientific article

Factors associated with population coverage of targeted malaria elimination (TME) in southern Savannakhet Province, Lao PDR.

scientific article published on 23 October 2017

Factors associated with reported diarrhoea episodes and treatment-seeking in an urban slum of Kolkata, India

scientific article published on June 2004

Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

scientific article

Field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population

scientific article

Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance

scientific article published on April 2015

Frequency of isolation of various subtypes and antimicrobial resistance of Shigella from urban slums of Karachi, Pakistan

scientific article published on 8 January 2009

Genetic diversity of El Tor strains of Vibrio cholerae O1 with hybrid traits isolated from Bangladesh and Mozambique

article

Geographic analysis of shigellosis in Vietnam

scientific article published on 28 December 2007

Global extent of chloroquine-resistant Plasmodium vivax - Authors' reply

scientific article published on June 2015

Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysis

scientific article

Healthcare use for diarrhoea and dysentery in actual and hypothetical cases, Nha Trang, Viet Nam.

scientific article published in June 2004

Herd immunity conferred by killed oral cholera vaccines in Bangladesh: a reanalysis

scientific article

Herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations and the implications for malaria elimination

scholarly article published 19 August 2018

History of malaria treatment as a predictor of subsequent subclinical parasitaemia: a cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia

scientific article published on 26 April 2016

How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria

scientific article

Immunogenicity and Protection From a Single Dose of Internationally Available Killed Oral Cholera Vaccine: A Systematic Review and Metaanalysis

scientific article published on 21 November 2017

Individual-level factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study

scientific article published in June 2017

Invasive salmonellosis among children admitted to a rural Tanzanian hospital and a comparison with previous studies

scientific article

Is HIV infection associated with an increased risk for cholera? Findings from a case-control study in Mozambique

scientific article published on 6 March 2008

Isolation of Salmonella enterica subspecies enterica serovar Paratyphi B dT+, or Salmonella Java, from Indonesia and alteration of the d-tartrate fermentation phenotype by disrupting the ORF STM 3356.

scientific article published in December 2006

Knowledge gaps in the construction of rural healthy homes: A research agenda for improved low-cost housing in hot-humid Africa

scientific article published on 10 October 2019

Lessons and implications from a mass immunization campaign in squatter settlements of Karachi, Pakistan: an experience from a cluster-randomized double-blinded vaccine trial [NCT00125047].

scientific article

Likely health outcomes for untreated acute febrile illness in the tropics in decision and economic models; a Delphi survey

scientific article

Limitations of malaria reactive case detection in an area of low and unstable transmission on the Myanmar-Thailand border

scientific article

Long-term effectiveness against cholera of oral killed whole-cell vaccine produced in Vietnam

article

Malaria Epidemiology in Kilifi, Kenya during the 21st Century: What Next?

scientific article

Malaria eradication and elimination: views on how to translate a vision into reality

scientific article published on 25 July 2015

Malaria vaccines: past, present and future

scientific article published on 23 September 2013

Mass administrations of antimalarial drugs ⬇️

scientific article published on October 1, 2003

Mass anti-malarial administration in western Cambodia: a qualitative study of factors affecting coverage

scientific article

Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials

scientific article published on 05 February 2020

Mass psychogenic illness following oral cholera immunization in Ca Mau City, Vietnam ⬇️

scientific article published on November 7, 2003

Methods for the field evaluation of quantitative G6PD diagnostics: a review

scientific article published on 11 September 2017

Model citizen

scientific article published in October 2017

Multidisciplinary studies of disease burden in the Diseases of the Most Impoverished Programme.

scientific article published on September 2004

Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage.

scientific article

Multilocus sequence typing analysis of Shigella flexneri isolates collected in Asian countries

scientific article

Novel Approaches to Control Malaria in Forested Areas of Southeast Asia

scientific article published on 07 May 2019

Novel Vector Control Approaches: The Future for Prevention of Zika Virus Transmission?

scientific article

Numerical Distributions of Parasite Densities During Asymptomatic Malaria

scientific article published on 17 December 2015

Oral cholera vaccine development and use in Vietnam

scientific article

Oral quinine for the treatment of uncomplicated malaria.

scientific article published on 21 July 2009

Organizational aspects and implementation of data systems in large-scale epidemiological studies in less developed countries

scientific article

Pandemic serovars (O3:K6 and O4:K68) of Vibrio parahaemolyticus associated with diarrhea in Mozambique: spread of the pandemic into the African continent.

scientific article

Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming

scientific article

Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania

scientific article published on July 2010

Performance of the Access Bio/CareStart rapid diagnostic test for the detection of glucose-6-phosphate dehydrogenase deficiency: A systematic review and meta-analysis

scientific article published on 13 December 2019

Persistent Plasmodium falciparum and Plasmodium vivax infections in a western Cambodian population: implications for prevention, treatment and elimination strategies

scientific article published on 24 March 2016

Peru-15, a live attenuated oral cholera vaccine, is safe and immunogenic in Bangladeshi toddlers and infants

scientific article published on 5 September 2006

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity

scientific article published on 03 December 2008

Plasmodium vivax population structure and transmission dynamics in Sabah Malaysia

scientific article

Plasmodium vivax treatments: what are we looking for?

scientific article published on December 2011

Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria

scientific article published on 26 November 2012

Potential cost-effectiveness of a rotavirus immunization program in rural China

scientific article published in October 2009

Pre-referral rectal artesunate in severe malaria

scientific article

Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial

scientific article published on 12 March 2012

Preventing cholera outbreaks through early targeted interventions.

scientific article

Primaquine radical cure of Plasmodium vivax: a critical review of the literature

scientific article

Private demand for cholera vaccines in Beira, Mozambique

scientific article published on 21 December 2006

Progress in Medicine: Experts Take Stock

scientific article published on 29 December 2015

Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

scientific article published on 14 May 2020

Randomized, controlled study of the safety and immunogenicity of Peru-15, a live attenuated oral vaccine candidate for cholera, in adult volunteers in Bangladesh

scientific article published on 15 July 2005

Rationale for short course primaquine in Africa to interrupt malaria transmission

scientific article

Reducing stunting among children: the potential contribution of diagnostics

scientific article published in Nature

Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba, Zanzibar

scientific article

Response to "Poor control vaccines in two randomised trials of malaria vaccine?".

scientific article published on 30 May 2009

Revaccination with locally-produced vi typhoid polysaccharide vaccine among chinese school-aged children: safety and immunogenicity findings

scientific article

Review of key knowledge gaps in glucose-6-phosphate dehydrogenase deficiency detection with regard to the safe clinical deployment of 8-aminoquinoline treatment regimens: a workshop report

scientific article

Risk factors for shigellosis in Thailand

scientific article

Safety and effectiveness of mass drug administration to accelerate elimination of artemisinin-resistant falciparum malaria: A pilot trial in four villages of Eastern Myanmar

scientific article published on 6 September 2017

Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults

scientific article

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

scientific article (publication date: 29 November 2010)

Safety of the recombinant cholera toxin B subunit, killed whole-cell (rBS-WC) oral cholera vaccine in pregnancy

scientific article

Salmonella paratyphi A rates, Asia

scientific article published in November 2005

Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria

scientific article published on 16 August 2012

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

scientific article (publication date: 2011)

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

scientific article published on 18 July 2019

Submicroscopic Plasmodium prevalence in relation to malaria incidence in 20 villages in western Cambodia

scientific article published on 31 January 2017

Surveillance of shigellosis by real-time PCR suggests underestimation of shigellosis prevalence by culture-based methods in a population of rural China

scientific article published on 15 October 2010

The Epidemiology of Cholera in Zanzibar: Implications for the Zanzibar Comprehensive Cholera Elimination Plan

scholarly article by Qifang Bi et al published 19 September 2018 in Journal of Infectious Diseases

The Future of the RTS,S/AS01 Malaria Vaccine: An Alternative Development Plan

scientific article

The acceptability of mass administrations of anti-malarial drugs as part of targeted malaria elimination in villages along the Thai-Myanmar border

scientific article published on 27 September 2016

The burden of diarrhoea, shigellosis, and cholera in North Jakarta, Indonesia: findings from 24 months surveillance

scientific article

The burden of invasive bacterial infections in Pemba, Zanzibar

scientific article

The burden of rotavirus diarrhea in Khanh Hoa Province, Vietnam: baseline assessment for a rotavirus vaccine trial

scientific article

The case for reactive mass oral cholera vaccinations

scientific article

The case for ring vaccinations with special consideration of oral cholera vaccines.

scientific article

The challenges of introducing routine G6PD testing into radical cure: a workshop report

scientific article

The dynamic of asymptomatic Plasmodium falciparum infections following mass drug administrations with dihydroarteminisin-piperaquine plus a single low dose of primaquine in Savannakhet Province, Laos

scholarly article published by Nicholas P J Day in 2018

The effect of mass administration of sulfadoxine-pyrimethamine combined with artesunate on malaria incidence: a double-blind, community-randomized, placebo-controlled trial in The Gambia

scientific article

The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam

scientific article

The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial

scientific article published on 6 March 2018

The failure of screening and treating as a malaria elimination strategy

scientific article published on 28 January 2014

The feasibility and acceptability of mass drug administration for malaria in Cambodia: a mixed-methods study

scholarly article published by Thomas J Peto in 2018

The high burden of cholera in children: comparison of incidence from endemic areas in Asia and Africa

scientific article

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial

article

The malaria and typhoid fever burden in the slums of Kolkata, India: data from a prospective community-based study

scientific article

The need for another typhoid fever vaccine

scientific article

The persistence and oscillations of submicroscopic Plasmodium falciparum and Plasmodium vivax infections over time in Vietnam: an open cohort study

scientific article published in February 2018

The prevalence, incidence and prevention of Plasmodium falciparum infections in forest rangers in Bu Gia Map National Park, Binh Phuoc province, Vietnam: a pilot study

scientific article

The probability of a sequential Plasmodium vivax infection following asymptomatic Plasmodium falciparum and P. vivax infections in Myanmar, Vietnam, Cambodia, and Laos

scientific article published on 30 December 2019

The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans

scientific article

The use of a computerized database to monitor vaccine safety in Viet Nam.

scientific article published on August 2005

The use of typhoid vaccines in Asia: the DOMI experience

scientific article

The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR

scientific article published on 03 January 2020

The vaccine data link in Nha Trang, Vietnam: a progress report on the implementation of a database to detect adverse events related to vaccinations

scientific article

The value of and challenges for cholera vaccines in Africa

scientific article

Therapy of uncomplicated malaria in children: a review of treatment principles, essential drugs and current recommendations

scientific article published on 24 July 2008

Towards malaria elimination in Savannakhet, Lao PDR: mathematical modelling driven strategy design

scientific article

Treatment uptake by individuals infected with Plasmodium falciparum in rural Gambia, West Africa.

scientific article published on 28 November 2002

Trend and disease burden of bacillary dysentery in China (1991-2000)

scientific article

Trends and disease burden of enteric fever in Guangxi province, China, 1994-2004

scientific article

Trends in malaria research in 11 Asian Pacific countries: an analysis of peer-reviewed publications over two decades

scientific article

Use of verbal autopsy to determine mortality patterns in an urban slum in Kolkata, India.

scientific article

Utilization and accessibility of healthcare on Pemba Island, Tanzania: implications for health outcomes and disease surveillance for typhoid fever

scientific article published on 3 December 2012

Vaccines for cholera control: does herd immunity play a role

scientific article

Vivax malaria and bacteraemia: a prospective study in Kolkata, India

scientific article published on 31 May 2013

Where chloroquine still works: the genetic make-up and susceptibility of Plasmodium vivax to chloroquine plus primaquine in Bhutan

scientific article

Why do people participate in mass anti-malarial administration? Findings from a qualitative study in Nong District, Savannakhet Province, Lao PDR (Laos).

scientific article published on 9 January 2018

Willingness to be vaccinated against shigella and other forms of dysentery: a comparison of three regions in Asia

scientific article published on 15 August 2005

“Nine Dimensions”: A multidisciplinary approach for community engagement in a complex postwar border region as part of the targeted malaria elimination in Karen/Kayin State, Myanmar

scholarly article by Decha Tangseefa et al published 18 September 2018 in Wellcome Open Research

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