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List of works by Andrew Pekosz

A novel real-time RT-PCR assay for influenza C tested in Peruvian children

scientific article published on September 2017

An immunosuppressed Syrian golden hamster model for SARS-CoV infection

scientific article

Animal models of congenital zika syndrome provide mechanistic insight into viral pathogenesis during pregnancy

scientific article published on 22 October 2020

Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 mice

scientific article published on 6 October 2011

Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality

scientific article published on 18 December 2020

Bidirectional virus secretion and nonciliated cell tropism following Andes virus infection of primary airway epithelial cell cultures

scientific article published in February 2006

Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread

scientific article published on 10 August 2005

Bird flu: A virus of our own hatching.

scientific article

CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation

scientific article published on 08 October 2020

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

scientific article published on 26 May 2020

COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva

scientific article published on 16 October 2020

Characterizing Emerging Canine H3 Influenza Viruses

scientific article published on 14 April 2020

Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers

scientific article published on 02 September 2020

Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers

scientific article published on 02 November 2020

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Delivery of woodchuck hepatitis virus-like particle presented influenza M2e by recombinant attenuated Salmonella displaying a delayed lysis phenotype

scientific article

Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways

scientific article published in January 2005

Deployment of convalescent plasma for the prevention and treatment of COVID-19

scientific article published on 07 April 2020

Differential antibody recognition of H3N2 vaccine and seasonal influenza virus strains based on age, vaccine status, and sex in the 2017-18 season

scientific article published on 04 June 2020

Differentiated cultures of primary hamster tracheal airway epithelial cells

scientific article

Distinct domains of the influenza a virus M2 protein cytoplasmic tail mediate binding to the M1 protein and facilitate infectious virus production

scientific article

Durable SARS-CoV-2 B cell immunity after mild or severe disease

scientific article published on 30 October 2020

Dysregulated immunity in SARS-CoV-2 infected pregnant women

scientific article published on 16 November 2020

Emerging viral diseases

scientific article (publication date: 2008)

Epizootics in Industrial Livestock Production: Preventable Gaps in Biosecurity and Biocontainment.

scientific article published on 4 September 2016

Estrogenic compounds reduce influenza A virus replication in primary human nasal epithelial cells derived from female, but not male, donors

scientific article

Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells

scientific article published on 26 September 2017

Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model.

scientific article

Extending the cytoplasmic tail of the influenza a virus M2 protein leads to reduced virus replication in vivo but not in vitro

scientific article published on 7 November 2007

Exuberant fibroblast activity compromises lung function via ADAMTS4

scientific article published on 28 October 2020

Fatal SARS-CoV-2 Inflammatory Syndrome and Myocarditis in an Adolescent: A Case Report

scientific article published on 10 November 2020

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping

scientific article published on 03 June 2020

Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses

scientific article

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses

scientific journal article

IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection

scientific article published on 28 February 2019

Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms during the 2014-15 influenza season

scientific article published on 01 January 2021

Identification of a membrane targeting and degradation signal in the p42 protein of influenza C virus

scientific article

IgM autoantibodies recognizing ACE2 are associated with severe COVID-19

scientific article published on 15 October 2020

Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2

scientific article published on 26 June 2020

Influenza A H1N1 pandemic strain evolution--divergence and the potential for antigenic drift variants.

scientific article

Influenza A Virus M2 Protein Apical Targeting Is Required for Efficient Virus Replication

scholarly article by Nicholas Wohlgemuth et al published 15 November 2018 in Journal of Virology

Influenza A virus infection of primary differentiated airway epithelial cell cultures derived from Syrian golden hamsters

scientific article

Influenza C virus CM2 integral membrane glycoprotein is produced from a polypeptide precursor by cleavage of an internal signal sequence

scientific article published on October 1998

Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture

scientific article

Influenza virus assays based on virus-inducible reporter cell lines

scientific article

Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins

scientific article

Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells

scientific article

Influenza virus-like particles containing M2 induce broadly cross protective immunity

scientific article (publication date: 18 January 2011)

Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells

scientific article

Intracellular localization of the severe acute respiratory syndrome coronavirus nucleocapsid protein: absence of nucleolar accumulation during infection and after expression as a recombinant protein in vero cells

scientific article

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

scientific article (publication date: 21 February 2017)

Mechanism for proton conduction of the M(2) ion channel of influenza A virus

scientific article (publication date: 24 March 2000)

Mind the gap: social media engagement by public health researchers

scientific article published on 14 January 2014

Mitigation of SARS-CoV-2 transmission at a large public university

scientific article published in 2022

Moving Forward: Recent Developments for the Ferret Biomedical Research Model

scientific article published on 17 July 2018

Mutations in the Influenza A virus M1 protein enhance virus budding to complement lethal mutations in the M2 cytoplasmic tail

scientific article published on 18 October 2017

Mutations in the membrane-proximal region of the influenza A virus M2 protein cytoplasmic tail have modest effects on virus replication

scientific article

Neuraminidase antigenic drift of H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding

scientific article published on 29 June 2020

No evidence of infection with avian influenza viruses among US poultry workers in the Delmarva Peninsula, Maryland and Virginia, USA

scientific article

Palmitoylation of the influenza A virus M2 protein is not required for virus replication in vitro but contributes to virus virulence

scientific article published on 24 June 2009

Pathogenesis and Molecular Mechanisms of Zika Virus

scientific article published on 9 September 2016

Permeation and activation of the M2 ion channel of influenza A virus.

scientific article published on October 2000

Production and Characterization of Monoclonal Antibodies Against the Nucleocapsid Protein of SARS-COV

article

Production of amphiregulin and recovery from influenza is greater in males than females.

scientific article published on 17 July 2018

Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females

scientific article (publication date: September 2016)

Prospects for oral replicating adenovirus-vectored vaccines

scientific article published on 22 May 2013

Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4

scientific article published on 18 November 2020

Repeat COVID-19 Molecular Testing: Correlation of SARS-CoV-2 Culture with Molecular Assays and Cycle Thresholds

scientific article published on 27 October 2020

Replication in cultured C2C12 muscle cells correlates with the neuroinvasiveness of California serogroup bunyaviruses.

scientific article published on June 1994

Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box.

scientific article published on June 1997

Respiratory pathogen diversity and co-infections in rural Zambia

scientific article published on 27 October 2020

Restricted replication of the live attenuated influenza A virus vaccine during infection of primary differentiated human nasal epithelial cells

scientific article

Reverse genetics of negative-strand RNA viruses: closing the circle

scientific article

Roles for the recycling endosome, Rab8, and Rab11 in hantavirus release from epithelial cells

scientific article

SARS Coronavirus Accessory Gene Expression and Function

article

SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors

scientific article published on 10 September 2020

SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy

scientific article published on 18 September 2020

Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance

scientific article

Seoul virus suppresses NF-kappaB-mediated inflammatory responses of antigen presenting cells from Norway rats

scientific article

Severe acute respiratory syndrome coronavirus gene 7 products contribute to virus-induced apoptosis

scientific article published on 8 August 2007

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

scientific article published on 28 June 2020

Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population

scientific article published on 07 August 2020

Sex-based biology and the rational design of influenza vaccination strategies.

scientific article

Sialic acid recognition is a key determinant of influenza A virus tropism in murine trachea epithelial cell cultures

scientific article

Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics

scientific article published on 3 January 2018

Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein

scientific article

Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b.

scientific article

Structure–function relationship of the M2 ion channel of influenza A virus

The CM2 Protein of Influenza C Virus Is an Oligomeric Integral Membrane Glycoprotein Structurally Analogous to Influenza A Virus M2and Influenza B Virus NB Proteins ⬇️

scientific article published on October 27, 1997

The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike

scientific article published on 09 December 2020

The Influenza A Virus M2 Protein trans-Complementation System Offers a Set of Tools for the Undergraduate Virology Laboratory.

scientific article published on 26 April 2019

The M2 protein of live, attenuated influenza vaccine encodes a mutation that reduces replication in human nasal epithelial cells

scientific article published on 24 October 2017

The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles

scientific article published on November 2006

The R35 residue of the influenza A virus NS1 protein has minimal effects on nuclear localization but alters virus replication through disrupting protein dimerization

scientific article

The RNA Binding Domain of Influenza A Virus NS1 Protein Affects Secretion of Tumor Necrosis Factor Alpha, Interleukin-6, and Interferon in Primary Murine Tracheal Epithelial Cells.

scientific article

The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cells

scientific article

The Xs and Y of immune responses to viral vaccines

scientific article published in May 2010

The cholesterol recognition/interaction amino acid consensus motif of the influenza A virus M2 protein is not required for virus replication but contributes to virulence

scientific article

The extracellular domain of La Crosse virus G1 forms oligomers and undergoes pH-dependent conformational changes.

scientific article published in November 1996

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence

The impact of sex, gender and pregnancy on 2009 H1N1 disease

scientific article

The influenza A virus M2 cytoplasmic tail is required for infectious virus production and efficient genome packaging

scientific article

The influenza C virus CM2 protein can alter intracellular pH, and its transmembrane domain can substitute for that of the influenza A virus M2 protein and support infectious virus production

scientific article published on 14 September 2011

The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex

scientific article published on 16 July 2008

The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses

scientific article

Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes

scientific article

Tropism and Infectivity of Influenza Virus, Including Highly Pathogenic Avian H5N1 Virus, in Ferret Tracheal Differentiated Primary Epithelial Cell Cultures ⬇️

scientific article published on December 19, 2012

Tyrosines in the influenza A virus M2 protein cytoplasmic tail are critical for production of infectious virus particles

scientific article

Variability of Salivary and Nasal Specimens for SARS-CoV-2 Detection

scientific article published on 12 October 2020

Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication

scientific article

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