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List of works by Robert J. Homer

A 34-year-old man presenting with gradual onset of shortness of breath and interstitial lung disease

scientific article published on April 2008

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

scientific article

A critical regulatory role for macrophage migration inhibitory factor in hyperoxia-induced injury in the developing murine lung

scientific article

A critical role of SHP-1 in regulation of type 2 inflammation in the lung

scientific article published on 23 October 2008

A role for matrix metalloproteinase 9 in IFNγ-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia

scientific article published on 7 January 2011

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

scholarly article

ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES AS MARKERS FOR SYSTEMIC AUTOIMMUNE DISEASE

article

Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

scientific article

Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cells

scientific article

Activation of the STAT pathway in acute lung injury

scientific article published on 16 January 2004

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

scientific article

Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway

scientific article

Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma

scientific article published in October 2004

Airway remodeling and RELM-β

article

An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection

scientific article published on 22 May 2014

Approach to the ground-glass nodule

scientific article published on 02 October 2011

Back to the future: historical perspective on the pathogenesis of idiopathic pulmonary fibrosis

scientific article

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

scientific article

Bcl-2–related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

article

Benign pulmonary epithelial inclusions within the pleura: a case report

scientific article published on 29 June 2007

CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung

scientific article

Case study review

scientific article

Cathepsin E promotes pulmonary emphysema via mitochondrial fission

scientific article

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

scientific article

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

scientific article

Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes

scientific article published on 18 July 2012

Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease

scientific article published on January 2016

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung

scientific article

Cutting Edge: Limiting MHC Class II Expression to Dendritic Cells Alters the Ability to Develop Th2- Dependent Allergic Airway Inflammation

scientific article published on 13 July 2009

Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro

scientific article published in April 2003

Cytokines

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia

scientific article published on 30 March 2007

Developmental regulation of NO-mediated VEGF-induced effects in the lung

scientific article published on 25 April 2008

Diagnosing idiopathic pulmonary fibrosis without a lung biopsy: honeycombing not required

scientific article

Differences in Pathology, Staging, and Treatment between HIV+ and Uninfected Patients with Microscopically Confirmed Hepatocellular Carcinoma

scientific article published on 01 October 2019

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

scientific article published on 23 March 2006

Drug sensitivity and allele-specificity of first-line osimertinib resistance EGFR mutations

scientific article published on 19 March 2020

Duodenal hemangioendothelioma: a case report ⬇️

scientific article published on 01 May 1998

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

scientific article published on 25 January 2024

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

scientific article

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

scientific article

Endobronchial Ultrasound-Guided Cautery-Assisted Transbronchial Forceps Biopsies: Safety and Sensitivity Relative to Transbronchial Needle Aspiration

scientific article published on 22 February 2016

Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production

scientific article published on 10 July 2008

Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection.

scientific article published on 4 August 2008

Eosinophilic pneumonia as a presentation of occult chronic granulomatous disease

scientific article published on September 1997

Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation.

scientific article published on 25 October 2010

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

scholarly article

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

scientific article

Genetic control of transforming growth factor-beta1-induced emphysema and fibrosis in the murine lung

scientific article published in August 2006

Genetic, serological and functional analysis of I-J molecules.

scientific article published on April 1985

Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide.

scientific article published in June 2009

High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

scientific article

High expression of mammalian target of rapamycin is associated with better outcome for patients with early stage lung adenocarcinoma

scientific article

Hubert Humphrey's bladder cancer

scientific article published in September 1994

Hyperoxia and interferon-γ-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway

scientific article published on June 2013

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

scientific article

IFN-gamma-dependent DNA injury and/or apoptosis are critical in cigarette smoke-induced murine emphysema

scientific article published in August 2006

IFN-γ acts on the airway epithelium to inhibit local and systemic pathology in allergic airway disease

scientific article

IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension

scientific article published on 2 November 2012

IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma

scientific article

IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells

scientific article published on 13 November 2006

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis

scientific article

Identification of EGFR mutation, KRAS mutation, and ALK gene rearrangement in cytological specimens of primary and metastatic lung adenocarcinoma.

scientific article

Idiopathic pulmonary fibrosis: new insights into pathogenesis

scientific article

Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.

scientific article

Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling

scientific article published on 5 February 2016

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

scientific article

Inhibition of Regulatory-Associated Protein of Mechanistic Target of Rapamycin Prevents Hyperoxia-Induced Lung Injury by Enhancing Autophagy and Reducing Apoptosis in Neonatal Mice.

scientific article published on 02 July 2016

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

scientific journal article

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

scientific article

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

scientific article published on 21 January 2005

Interferon gamma induction of pulmonary emphysema in the adult murine lung

scientific article

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

scientific article published on September 2001

Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9.

scientific article published in November 2002

Interstitial lung disease in the connective tissue diseases

scientific article published on March 2012

Massive cavitary pulmonary rheumatoid nodules in a patient with HIV.

scientific article published in October 2006

Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling

scientific article published on 28 July 2016

Molecular classification of nonsmall cell lung cancer using a 4-protein quantitative assay

article

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

scientific article

New insights into the pathogenesis of asthma

article

New insights into the pathogenesis of asthma

Of lungs, lipids, and lollipops

scientific article published in November 2009

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells

scientific article published on 21 June 2016

Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

article

P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway

scientific article published on 11 October 2007

Pathologists' staging of multiple foci of lung cancer: poor concordance in absence of dramatic histologic or molecular differences

scientific article published on May 2015

Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis

scientific article published on 8 September 2016

Preparation, characterization, and evaluation of a monoclonal antibody against the rabbit platelet glycoprotein IIb/IIIa in an experimental angioplasty model

article

Primary malignant melanoma of the transverse colon: report of a case and review of the literature

scientific article published on October 2007

Pulmonary expression of leukemia inhibitory factor induces B cell hyperplasia and confers protection in hyperoxia

scientific article published on 2 June 2003

Pulmonary manifestations of rheumatoid arthritis

scientific article published on September 2010

RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism

scientific article published on 28 January 2011

Recent advances in pulmonary fibrosis: implications for scleroderma

scientific article

Regression of murine lung tumors by the let-7 microRNA

scientific article

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

scientific article

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

scientific article

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

scientific article

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

scientific article

Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs

scientific article (publication date: 2016)

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema

scientific article

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling

scientific article published on 26 January 2006

Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease

scientific article published on August 2011

Role of tissue protection in lethal respiratory viral-bacterial coinfection

scientific article published on 25 April 2013

SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.

scientific article published on 13 October 2016

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

scientific article

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

scientific article published on 6 December 2012

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

scientific article published on 08 July 2020

State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic mice

scientific article published on August 2006

Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9.

scientific article

T cell unresponsiveness correlates with quantitative TCR levels in a transgenic model

article

T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production

scientific article

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

scientific article

Targeted Lung Expression of Interleukin-11 Enhances Murine Tolerance of 100% Oxygen and Diminishes Hyperoxia-Induced DNA Fragmentation

scientific article published on 01 July 1999

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction

scientific article published on December 1996

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

scientific article

The Airway in Idiopathic Pulmonary Fibrosis: Protecting the Lung or Promoting Disease?

scientific article published on May 2016

Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis

scientific article published on 16 November 2020

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

scientific article

Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma

scientific article

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

scientific article published on 5 January 2007

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

scientific article

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways

scientific article

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

scientific article

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

scientific article

Zika virus causes testicular atrophy

scientific article (publication date: February 2017)

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