List of works - Robert J. Homer

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

scientific article

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

scientific article published on September 2001

Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

scientific article

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

scientific article

Regression of murine lung tumors by the let-7 microRNA

scientific article

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

scientific article

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

scientific article

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

scientific article

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

scholarly article

Interferon gamma induction of pulmonary emphysema in the adult murine lung

scientific article

New insights into the pathogenesis of asthma

article

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

scientific article

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

scientific article

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

scientific journal article

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

scientific article

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

scientific article

Role of tissue protection in lethal respiratory viral-bacterial coinfection

scientific article published on 25 April 2013

T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production

scientific article

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction

scientific article published on December 1996

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

scientific article

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

scientific article

Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9.

scientific article published in November 2002

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

scientific article

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

scientific article published on 5 January 2007

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

scientific article

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways

scientific article

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

scientific article

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

scientific article

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

scientific article

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

scientific article

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

scientific article

Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma

scientific article

Activation of the STAT pathway in acute lung injury

scientific article published on 16 January 2004

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

scientific article

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling

scientific article published on 26 January 2006

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function

scientific article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

scientific article

Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease

scientific article published on August 2011

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

scientific article

Zika virus causes testicular atrophy

scientific article (publication date: February 2017)

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

scientific article published on 6 December 2012

Developmental regulation of NO-mediated VEGF-induced effects in the lung

scientific article published on 25 April 2008

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

scholarly article

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

scientific article published on 21 January 2005

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

scientific article published on 23 March 2006

Idiopathic pulmonary fibrosis: new insights into pathogenesis

scientific article

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

scientific article

Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway

scientific article

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia

scientific article published on 30 March 2007

List of works by Robert J. Homer

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

Regression of murine lung tumors by the let-7 microRNA

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung.

Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

Interferon gamma induction of pulmonary emphysema in the adult murine lung

New insights into the pathogenesis of asthma

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

Role of tissue protection in lethal respiratory viral-bacterial coinfection

T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production

Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis

Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling

Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9.

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

Transforming growth factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent, bid-activated pathway that involves matrix metalloproteinase-12.

Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes

Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease

Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo

Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma

Activation of the STAT pathway in acute lung injury

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

Zika virus causes testicular atrophy

Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis

Developmental regulation of NO-mediated VEGF-induced effects in the lung

Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

Differential expression of chitinases identify subsets of murine airway epithelial cells in allergic inflammation

Idiopathic pulmonary fibrosis: new insights into pathogenesis

Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis

Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway

Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia