List of works - Thiago Moreno L Souza

1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses.

scientific article

2,8-bis(trifluoromethyl)quinoline analogs show improved anti-Zika virus activity, compared to mefloquine

scientific article (publication date: December 2016)

An observational clinical case of Zika virus-associated neurological disease is associated with primary IgG response and enhanced TNF levels.

scientific article published on 17 May 2018

Anti HSV-1 Alkaloids from a Feeding Deterrent Marine Sponge of the Genus Aaptos

article

Antiviral resistance surveillance for influenza A virus in Brazil: investigation on 2009 pandemic influenza A (H1N1) resistance to oseltamivir.

scientific article published on 23 July 2011

Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

scientific article published on 06 April 2020

Atazanavir, alone or in combination with ritonavir, inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

scientific article published on 05 August 2020

Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

scientific article

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

scientific article published on 04 February 2019

Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies

scientific article

Clinical Manifestations of Zika Virus Infection, Rio de Janeiro, Brazil, 2015 ⬇️

scientific article

Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture

scientific article published on 22 February 2022

Correction: Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

scientific article published on 30 October 2015

Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

scientific article published on 24 April 2017

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

article published in 2013

Detection of Zika Virus in April 2013 Patient Samples, Rio de Janeiro, Brazil

scientific article published on 15 December 2017

Detection of oseltamivir-resistant pandemic influenza A(H1N1)pdm2009 in Brazil: can community transmission be ruled out?

scientific article (publication date: 2013)

Detection of the influenza A(H1N1)pdm09 virus carrying the K-15E, P83S and Q293H mutations in patients who have undergone bone marrow transplant

scientific article

Development of standard methods for Zika virus propagation, titration, and purification

scientific article

Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

article

H1N1pdm influenza infection in hospitalized cancer patients: clinical evolution and viral analysis

scientific article

H1N1pdm09 adjuvanted vaccination in HIV-infected adults: a randomized trial of two single versus two double doses.

scientific article

HIV controllers suppress viral replication and evolution and prevent disease progression following intersubtype HIV-1 superinfection

scientific article published on 01 March 2019

HIV-1 and its gp120 inhibits the influenza A(H1N1)pdm09 life cycle in an IFITM3-dependent fashion

scientific article

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

scientific article

Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology

scientific article published on 22 April 2022

Identification of 1-Aryl-1H-1,2,3-triazoles as Potential New Antiretroviral Agents

scientific article published on 6 September 2017

Immunogenicity and sustainability of the immune response in Brazilian HIV-1-infected individuals vaccinated with inactivated triple influenza vaccine

scientific article

Influenza virus RNA polymerase may be activated inside the virion

scientific article published on 05 November 2018

Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone

scientific article published on 17 September 2007

Inhibitory effect of microalgae and cyanobacteria extracts on influenza virus replication and neuraminidase activity

scientific article published on 26 October 2018

Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice

scientific article (publication date: 2015)

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

scientific article published on 16 December 2020

Molecular findings from influenza A(H1N1)pdm09 detected in patients from a Brazilian equatorial region during the pandemic period.

scientific article

N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity

scientific article

New efavirenz derivatives and 1,2,3-triazolyl-phosphonates as inhibitors of reverse transcriptase of HIV-1

article

Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19

scientific article published on 14 April 2022

Polymorphisms at residue 222 of the hemagglutinin of pandemic influenza A(H1N1)pdm09: association of quasi-species to morbidity and mortality in different risk categories

scientific article

Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum.

scientific article published on September 2017

SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.

scientific article published on 22 September 2007

Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

scientific article published on 25 August 2017

Synthesis and anti-HSV-1 activity of new 1,2,3-triazole derivatives

scientific article published on 02 March 2011

Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines

scientific article published on 01 February 2012

Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives

scientific article

The alkaloid 4-methylaaptamine isolated from the sponge Aaptos aaptos impairs Herpes simplex virus type 1 penetration and immediate-early protein synthesis

scientific article published on 6 February 2007

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

scientific article

The compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase

scientific article published on May 2008

The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme

article

The effects of neurotrophins and the neuropeptides VIP and PACAP on HIV-1 infection: histories with opposite ends

scientific article published on March 2014

The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages.

scientific article

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo

scientific article published on 30 January 2019

List of works by Thiago Moreno L Souza

1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses.

2,8-bis(trifluoromethyl)quinoline analogs show improved anti-Zika virus activity, compared to mefloquine

An observational clinical case of Zika virus-associated neurological disease is associated with primary IgG response and enhanced TNF levels.

Anti HSV-1 Alkaloids from a Feeding Deterrent Marine Sponge of the Genus Aaptos

Antiviral resistance surveillance for influenza A virus in Brazil: investigation on 2009 pandemic influenza A (H1N1) resistance to oseltamivir.

Atazanavir inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

Atazanavir, alone or in combination with ritonavir, inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies

Clinical Manifestations of Zika Virus Infection, Rio de Janeiro, Brazil, 2015 ⬇️

Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture

Correction: Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin

Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

Detection of Zika Virus in April 2013 Patient Samples, Rio de Janeiro, Brazil

Detection of oseltamivir-resistant pandemic influenza A(H1N1)pdm2009 in Brazil: can community transmission be ruled out?

Detection of the influenza A(H1N1)pdm09 virus carrying the K-15E, P83S and Q293H mutations in patients who have undergone bone marrow transplant

Development of standard methods for Zika virus propagation, titration, and purification

Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

H1N1pdm influenza infection in hospitalized cancer patients: clinical evolution and viral analysis

H1N1pdm09 adjuvanted vaccination in HIV-infected adults: a randomized trial of two single versus two double doses.

HIV controllers suppress viral replication and evolution and prevent disease progression following intersubtype HIV-1 superinfection

HIV-1 and its gp120 inhibits the influenza A(H1N1)pdm09 life cycle in an IFITM3-dependent fashion

Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1).

Human endogenous retrovirus K in the respiratory tract is associated with COVID-19 physiopathology

Identification of 1-Aryl-1H-1,2,3-triazoles as Potential New Antiretroviral Agents

Immunogenicity and sustainability of the immune response in Brazilian HIV-1-infected individuals vaccinated with inactivated triple influenza vaccine

Influenza virus RNA polymerase may be activated inside the virion

Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone

Inhibitory effect of microalgae and cyanobacteria extracts on influenza virus replication and neuraminidase activity

Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice

Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

Molecular findings from influenza A(H1N1)pdm09 detected in patients from a Brazilian equatorial region during the pandemic period.

N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity

New efavirenz derivatives and 1,2,3-triazolyl-phosphonates as inhibitors of reverse transcriptase of HIV-1

Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19

Polymorphisms at residue 222 of the hemagglutinin of pandemic influenza A(H1N1)pdm09: association of quasi-species to morbidity and mortality in different risk categories

Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum.

SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.

Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae

Synthesis and anti-HSV-1 activity of new 1,2,3-triazole derivatives

Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines

Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives

The alkaloid 4-methylaaptamine isolated from the sponge Aaptos aaptos impairs Herpes simplex virus type 1 penetration and immediate-early protein synthesis

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication

The compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase

The dolabellane diterpene Dolabelladienetriol is a typical noncompetitive inhibitor of HIV-1 reverse transcriptase enzyme

The effects of neurotrophins and the neuropeptides VIP and PACAP on HIV-1 infection: histories with opposite ends

The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages.

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo