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List of works by Jan M. Deussing

A hypomorphic vasopressin allele prevents anxiety-related behavior

scientific article

A robust and reliable non-invasive test for stress responsivity in mice

scientific article

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.

scientific article published on 19 July 2013

Activation of the mouse odorant receptor 37 subsystem coincides with a reduction of novel environment-induced activity within the paraventricular nucleus of the hypothalamus

scientific article published on 24 January 2015

Adrenal and Ovarian Phenotype of a Tissue-Specific Urocortin 2-Overexpressing Mouse Model

scientific article published on 5 May 2015

Amygdala and neocortex: common origins and shared mechanisms

scientific article published on 01 September 2007

An integrated genome research network for studying the genetics of alcohol addiction

scientific article published on October 2010

Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans

scientific article (publication date: November 2014)

Behavioral phenotyping of Nestin-Cre mice: implications for genetic mouse models of psychiatric disorders

scientific article published on 12 April 2014

Beware of your Cre-Ation: lacZ expression impairs neuronal integrity and hippocampus-dependent memory

scientific article published on 22 April 2016

Biomimetic screening of class-B G protein-coupled receptors.

scientific article

Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high anxiety-related behavior.

scientific article

Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking

scientific article published on 23 November 2011

CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery.

scientific article published on 23 August 2016

CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting.

scientific article published on 18 May 2016

Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery.

scientific article

Cathepsin J, a novel murine cysteine protease of the papain family with a placenta-restricted expression

scientific journal article

Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells

scientific article

Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus ⬇️

scientific article published on April 17, 1998

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation ⬇️

scientific article published on April 14, 1998

Cerebellar Learning Properties Are Modulated by the CRF Receptor

scientific article published on 22 June 2018

Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety

scientific article published on 21 May 2018

Circadian rhythms of basal orexin levels in the hypothalamus are not influenced by an impaired corticotropin-releasing hormone receptor type 1 system.

scientific article published on 18 April 2009

Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function

scientific article

Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system

scientific article published on 01 November 2008

Conditional RNAi in mice.

scientific article published on 10 August 2010

Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.

scientific article published on 13 May 2008

Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus.

scientific article published on 26 October 2011

Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif

scientific article published on 9 September 2015

Corticotropin-releasing factor (CRF) receptor type 1-dependent modulation of synaptic plasticity

scientific article published on 26 January 2007

Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas.

scientific article

Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety.

scientific article

Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models

scientific article

Deficiency of corticotropin-releasing hormone type-2 receptor alters sleep responses to bacterial lipopolysaccharide in mice

scientific article

Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients

scientific article

Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence

scientific article published on December 2016

Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice.

scientific article

Distinct protease requirements for antigen presentation in vitro and in vivo.

scientific article published in March 2010

Early effects of a high-caloric diet and physical exercise on brain volumetry and behavior: a combined MRI and histology study in mice

scientific article

Early-life stress-induced anxiety-related behavior in adult mice partially requires forebrain corticotropin-releasing hormone receptor 1.

scientific article published on 4 June 2012

Enriched environment impacts trimethylthiazoline-induced anxiety-related behavior and immediate early gene expression: critical role of Crhr1.

scientific article published on 20 May 2014

Erratum: Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients

article

Evidence for the role of corticotropin-releasing factor in major depressive disorder

scientific article

Expression profiling identifies the CRH/CRH-R1 system as a modulator of neurovascular gene activity

scientific article published on 7 February 2007

Fkbp52 heterozygosity alters behavioral, endocrine and neurogenetic parameters under basal and chronic stress conditions in mice.

scientific article published on 27 May 2012

Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits

scientific article

Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor.

scientific article

Gene expression profiling following maternal deprivation: involvement of the brain Renin-Angiotensin system

scientific article published on 14 May 2009

Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein

scientific article

Gene targeting of the cysteine peptidase cathepsin H impairs lung surfactant in mice

scientific article

Genetic mouse models for behavioral analysis through transgenic RNAi technology

scientific article published on 2 June 2008

Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.

scientific article

Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.

scientific article published in September 2011

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality.

scientific article

Histone Modifications in Major Depressive Disorder and Related Rodent Models.

scientific article published on January 2017

Identification and characterization of a dense cluster of placenta-specific cysteine peptidase genes and related genes on mouse chromosome 13.

scientific article published in February 2002

Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety.

scientific article

Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.

scientific article published on December 2010

Inferior olive CRF plays a role in motor performance under challenging conditions.

scientific article

Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD).

scientific article published on 4 February 2017

Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress.

scientific article published on 14 September 2003

Local CRH signaling promotes synaptogenesis and circuit integration of adult-born neurons

scientific article

Local Optogenetic Induction of Fast (20-40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity

scientific article published on 26 April 2016

MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults

scientific article

MicroRNA-9 controls dendritic development by targeting REST.

scientific article

Mn2+ dynamics in manganese-enhanced MRI (MEMRI): Cav1.2 channel-mediated uptake and preferential accumulation in projection terminals

scientific article published on 19 December 2017

Mouse procathepsin E gene: molecular organisation and chromosomal localisation

scientific article published in May 1998

NPTX2 is a key component in the regulation of anxiety.

scientific article published on 11 May 2018

Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss.

scientific article published on 5 May 2013

Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition

scientific article published on 12 January 2015

Optogenetic evocation of field inhibitory postsynaptic potentials in hippocampal slices: a simple and reliable approach for studying pharmacological effects on GABAA and GABAB receptor-mediated neurotransmission.

scientific article published on 22 January 2014

PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions

scientific article

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.

scientific article

Placental cathepsin M is alternatively spliced and exclusively expressed in the spongiotrophoblast layer.

scientific article

Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction

scientific article published on 8 April 2016

Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine

scientific article published on 16 July 2008

Profiling trait anxiety: transcriptome analysis reveals cathepsin B (Ctsb) as a novel candidate gene for emotionality in mice

scientific article (publication date: 2011)

Region-specific roles of the corticotropin-releasing factor-urocortin system in stress.

scientific article

Roles of prefrontal cortex and paraventricular thalamus in affective and mechanical components of visceral nociception.

scientific article published on 6 August 2015

Sequencing on the SOLiD 5500xl System - in-depth characterization of the GC bias

scientific article published on 27 April 2017

Stress peptides sensitize fear circuitry to promote passive coping

scientific article published on 14 June 2018

Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function.

scientific article published on 11 January 2016

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

scientific article

TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies

scientific article published on 6 April 2010

Targeted mutagenesis tools for modelling psychiatric disorders.

scientific article published on 10 September 2013

The Corticotropin-Releasing Factor Family: Physiology of the Stress Response

scientific article published on 01 October 2018

The genes of the lysosomal cysteine proteinases cathepsin B, H, L, and S map to different mouse chromosomes

scientific article published on 01 April 1997

The optogenetic (r)evolution ⬇️

scientific article published on December 20, 2011

Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices

scientific article published on 12 February 2011

Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer.

scientific article published in May 2006

Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele

article

Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics.

scientific article published on 18 July 2016

Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain.

scientific article published on 25 March 2007

Urocortin 2 modulates aspects of social behaviour in mice

scientific article published on 26 May 2012

Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.

scientific article published on July 2010

Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

scientific article published in October 2012

Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation

scientific article published in February 2011

Wake-promoting effects of orexin: Its independent actions against the background of an impaired corticotropine-releasing hormone receptor system

scientific article

cAMP-dependent cell differentiation triggered by activated CRHR1 in hippocampal neuronal cells.

scientific article

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