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List of works by Michael G. Roth

5-Azacitidine Monotherapy Followed by Related Haploidentical Hematopoietic Stem Cell Transplantation Achieves Durable Remission in a Pediatric Patient With Acute Undifferentiated Leukemia Refractory to High-Dose Chemotherapy

scientific article published on 23 February 2016

A Novel Inhibitor of Topoisomerase I Is Selectively Toxic for a Subset of Non-Small Cell Lung Cancer Cell Lines.

scientific article

A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer

scientific article

A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance

scientific article

A new biology of diabetes revealed by leptin

scientific article

A point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion.

scientific article

A quarter causing intermittent gastric outlet obstruction ⬇️

scientific article published on January 1, 2012

A review of psychological symptoms and post-traumatic growth among adolescent and young adult survivors of childhood cancer

scientific article published on 06 November 2020

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin ⬇️

scientific article published on August 1, 1991

ARNO and ARF6 Regulate Axonal Elongation and Branching through Downstream Activation of Phosphatidylinositol 4-Phosphate 5-Kinase α ⬇️

scientific article published on October 17, 2003

Action of brefeldin A blocked by activation of a pertussis-toxin-sensitive G protein

scientific article published in Nature

Airway and lung remodelling in chronic pulmonary obstructive disease: a role for muscarinic receptor antagonists?

scientific article

Amino acid sequence requirements of the transmembrane and cytoplasmic domains of influenza virus hemagglutinin for viable membrane fusion

scientific article

An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production

scientific article published on 16 December 2015

An assessment of the current state of palliative care education in pediatric hematology/oncology fellowship training

scientific article published on 01 October 2009

An internalization-competent influenza hemagglutinin mutant causes the redistribution of AP-2 to existing coated pits and is colocalized with AP-2 in clathrin free clusters.

scientific article

Apical and basolateral coated pits of MDCK cells differ in their rates of maturation into coated vesicles, but not in the ability to distinguish between mutant hemagglutinin proteins with different internalization signals.

scientific article

Attitudes and practices of pediatric oncologists regarding methadone use in the treatment of cancer-related pain: results of a North American Survey

scientific article published on 01 March 2013

CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression.

scientific article published on 23 September 2017

Career burnout among pediatric oncologists ⬇️

scientific article published on May 5, 2011

Casein kinase I regulates membrane binding by ARF GAP1.

scientific article

Cell biology: porter and sorter

scientific article published on 01 April 2008

Cellular expression and function of phospholipase D1.

scientific article

Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins.

scientific article

Characterization of cholesterol homeostasis in telomerase-immortalized Tangier disease fibroblasts reveals marked phenotype variability.

scientific article

Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor

scientific article published on 11 September 2011

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.

scientific article published on 11 April 2018

Comprehensive mapping of the human kinome to epidermal growth factor receptor signaling

scientific article

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

scientific article published on 5 June 2017

Dapsone-induced DRESS after infliximab-induced vasculitis: a case of cerebral infarction in the context of multiple drug reactions

scientific article published on 17 December 2020

Day One Talk: parent preferences when learning that their child has cancer ⬇️

scientific article published on June 13, 2013

Deformity Angular Ratio Describes the Severity of Spinal Deformity and Predicts the Risk of Neurologic Deficit in Posterior Vertebral Column Resection Surgery

scientific article published on 4 March 2016

Degradation of mutant influenza virus hemagglutinins is influenced by cytoplasmic sequences independent of internalization signals.

scientific article published in January 1996

Detection of circulating tumor DNA in patients with osteosarcoma.

scientific article published on 18 January 2018

Development and validation of a prognostic model to predict recovery following intracerebral hemorrhage

scientific article published on 13 March 2006

Development of acute lymphoblastic leukemia following treatment for acute myeloid leukemia in children with Down syndrome: A case report and retrospective review of Children's Oncology Group acute myeloid leukemia trials

scientific article published on 25 March 2019

Differently anchored influenza hemagglutinin mutants display distinct interaction dynamics with mutual rafts ⬇️

scientific article published on November 17, 2003

Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma

scientific article published in Scientific Reports

Dynamic or stable interactions of influenza hemagglutinin mutants with coated pits. Dependence on the internalization signal but not on aggregation.

scientific article

Eltrombopag can overcome the anti-megakaryopoietic effects of lenalidomide without increasing proliferation of the malignant myelodysplastic syndrome/acute myelogenous leukemia clone

scientific article

Eltrombopag for the treatment of thrombocytopenia in patients with malignant and non-malignant hematologic disorders

scientific article

Eltrombopag inhibits the proliferation of leukemia cells via reduction of intracellular iron and induction of differentiation

scientific article

Endocytosis of chimeric influenza virus hemagglutinin proteins that lack a cytoplasmic recognition feature for coated pits.

scientific article published on July 1996

Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized

scientific article

Evaluating the potential of vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamide.

scientific article published on 05 July 2008

Evaluation and characterization of the hyt/hyt hypothyroid mouse. II. Abnormalities of TSH and the thyroid gland

scientific article published on 01 May 1989

Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles

scientific article

Exo1: a new chemical inhibitor of the exocytic pathway

scientific article

Exploring food preparation practices in families with and without school-aged childhood cancer survivors

scientific article published on 20 September 2019

Exploring the trilemma of cost-efficiency, landscape impact and regional equality in onshore wind expansion planning

scientific article published in 2022

Features of influenza HA required for apical sorting differ from those required for association with DRMs or MAL.

scientific article published on December 2003

Ganglioside GD2 as a therapeutic target for antibody-mediated therapy in patients with osteosarcoma.

scientific article published on 25 October 2013

Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma

scientific article

Genetically transforming human osteoblasts to sarcoma: development of an osteosarcoma model

scientific article

Genome-wide siRNA screen reveals coupling between mitotic apoptosis and adaptation

scientific article published on 14 July 2014

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

scientific article

Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway

scientific article

Glucagon therapeutics, dawn of a new era for diabetes care.

scientific article published on 04 January 2016

Glycosaminoglycan analysis in brain stems from animals infected with the bovine spongiform encephalopathy agent

scientific article

H2.0-like Homeobox Regulates Early Hematopoiesis and Promotes Acute Myeloid Leukemia ⬇️

scientific article published on August 14, 2012

HER2-Targeted Therapy in Osteosarcoma

scientific article published on 01 January 2020

Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway

scientific article

Hierarchy of sorting signals in chimeras of intestinal lactase-phlorizin hydrolase and the influenza virus hemagglutinin.

scientific article published on March 1999

High-Dose Chemotherapy with Stem Cell Rescue in Desmoplastic Small Round Cell Tumor: A Single-Institution Experience and Review of the Literature.

scientific article

High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

scientific article

Host modulators of H1N1 cytopathogenicity

scientific article

Identifying predictive factors for posttransplant lymphoproliferative disease in pediatric solid organ transplant recipients with Epstein-Barr virus viremia

scientific article

Image-based genome-wide siRNA screen identifies selective autophagy factors

scientific article

Immunolocalisation of phospholipase D1 on tubular vesicular membranes of endocytic and secretory origin

scientific article published on 01 August 2001

Impact of Lagtime, Health Insurance Type, and Income Status at Diagnosis on the Long-Term Survival of Adolescent and Young Adult Cancer Patients

scientific article published on 14 July 2020

Impact of a Genetic Evaluation Initiative to Increase Access to Genetic Services for Adolescent and Young Adults at a Tertiary Cancer Hospital

scientific article published on 19 August 2020

In vivo, noninvasive functional measurements of bone sarcoma using diffuse optical spectroscopic imaging

scientific article published in December 2017

Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines

scientific article

Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export

scientific article published on February 2012

Initial in vivo testing of TPO-receptor agonist eltrombopag in osteosarcoma patient-derived xenograft models by the pediatric preclinical testing consortium

scientific article published on 17 August 2020

Intra-articular solitary fibrous tumor of the knee

scientific article published on 09 March 2018

Land Tenure and Investment in African Agriculture: Theory and Evidence

article

Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis: Impact of Family History.

scientific article published on 20 April 2018

Meal planning values impacted by the cancer experience in families with school-aged survivors-a qualitative exploration and recommendations for intervention development

scientific article published on 26 June 2019

Mechanical analysis of the vascularized fibular graft prosthetic composite (VFGPC) for internal hemipelvectomy reconstruction.

scientific article published on 22 May 2017

Minimal PU.1 reduction induces a preleukemic state and promotes development of acute myeloid leukemia.

scientific article published on 7 September 2015

Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans

scientific article

Molecular mechanisms of PLD function in membrane traffic.

scientific article published on 31 March 2008

Muscarinic receptors and their antagonists in COPD: anti-inflammatory and antiremodeling effects

scientific article

Mutations in the Middle of the Transmembrane Domain Reverse the Polarity of Transport of the Influenza Virus Hemagglutinin in MDCK Epithelial Cells ⬇️

scientific article published on July 13, 1998

New candidates for vesicle coat proteins

scientific article

Opposition from Within

Pediatric Hematologists Report Infrequent Prognosis Discussions in the Routine Care of Children with Sickle Cell Disease

scientific article published on 01 January 2020

Pediatric Oncology Provider Views on Performing a Biopsy of Solid Tumors in Children with Relapsed or Refractory Disease for the Purpose of Genomic Profiling.

scientific article published on 26 July 2016

Pediatric oncologist willingness to offer germline TP53 testing in osteosarcoma.

scientific article published on 3 January 2018

Pediatric oncologists' views toward the use of complementary and alternative medicine in children with cancer

scientific article published on 01 March 2009

Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex

scientific article published on 01 May 1997

Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

scientific article published on March 2000

Phosphoinositides in constitutive membrane traffic.

scientific article published in July 2004

Phospholipase D as an effector for ADP-ribosylation factor in the regulation of vesicular traffic.

scientific article

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A

scientific article

Physician perspectives on compassionate use in pediatric oncology

scientific article published on 08 November 2018

Position and orientation control of an omni-directional mobile rehabilitation robot

Provider views on the management of Ewing sarcoma of the spine and pelvis

scientific article published on 16 October 2017

PtK1 cells contain a nondiffusible, dominant factor that makes the Golgi apparatus resistant to brefeldin A ⬇️

scientific article published on June 1, 1991

Review of recent non-hyperbaric oxygen interventions for mild traumatic brain injury

scientific article published in August 2016

Role of Stone-Wales defects on the interfacial interactions among graphene, carbon nanotubes, and Nylon 6: A first-principles study

scientific article published on 01 August 2018

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

scientific article published on February 1999

SAR-Based Optimization of a 4-Quinoline Carboxylic Acid Analogue with Potent Antiviral Activity ⬇️

scientific article published on June 13, 2013

SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers

scientific article (publication date: 19 January 2017)

SUN-598 Neck Pain as an Initial Presentation of Medullary Thyroid Cancer.

scientific article published on 30 April 2019

SV40 virus expression vectors.

scientific article published on January 1994

Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.

scientific article published on 7 April 2013

Short-Term Changes in Cardiac Function in Osteosarcoma Patients Receiving Anthracyclines

scientific article published on 22 February 2019

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

scientific article (publication date: February 2009)

Stem Cell Transplant for Children with Sickle Cell Anemia: Parent and Patient Interest ⬇️

scientific article published on May 29, 2012

Studies toward the Unique Pederin Family Member Psymberin: Structure–Activity Relationships, Biochemical Studies, and Genetics Identify the Mode-of-Action of Psymberin ⬇️

scientific article published on November 13, 2012

Studying Spatial Distributions of Influenza Hemagglutinin on the Plasma Membrane of Fibroblasts: A Work in Progress

Sustained molecular response following a failed attempt of tyrosine kinase inhibitor discontinuation & the effects on growth in a child with chronic myeloid leukemia: not always a short story

scientific article published on 29 April 2020

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

scientific article

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

scientific article published on 24 October 2013

TDP-43 identified from a genome wide RNAi screen for SOD1 regulators

scientific article

Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R).

scientific article published on 30 July 2016

Targeting QseC signaling and virulence for antibiotic development

scientific article

The Children's Oncology Group Adolescent and Young Adult Responsible Investigator Network: A New Model for Addressing Site-Level Factors Impacting Clinical Trial Enrollment

scientific article published on 20 February 2020

The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation

scientific article published on 23 April 2015

The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation

scientific article

The case for catch-up human papillomavirus vaccination in at-risk populations: Rural communities and survivors of pediatric and young adult cancers

scientific article published on 16 October 2020

The effect of bone morphogenetic protein-2 on osteosarcoma metastasis.

scientific article

The feasibility of implementing a communication skills training course in pediatric hematology/oncology fellowship

scientific article published on 6 December 2016

The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease

scientific article

The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1

scientific article

The non-geometric¯P Swave in high-resolution seismic data: observations and modelling

The role of lipid signaling in constitutive membrane traffic.

scientific article published on August 1997

Thrombotic disorders

scientific article published on January 2011

To B(MP-2) or Not To B(MP-2): Cytokines and Tumor Surgery—Letter

scientific article

Tumor tracking and motion compensation with an adaptive tumor tracking system (ATTS): System description and prototype testing.

scientific article published on September 2008

Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells.

scientific article published on October 1998

Tyrosine-dependent Basolateral Sorting Signals Are Distinct from Tyrosine-dependent Internalization Signals ⬇️

scientific article published on October 17, 1997

Utility of Motor and Somatosensory Evoked Potentials for Neural Thermoprotection in Ablations of Musculoskeletal Tumors

scientific article published on 24 April 2020

Variability in the reported management of pulmonary metastases in osteosarcoma

scientific article

XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.

scientific article published on 28 September 2016

microRNA-23a contributes to asthma by targeting BCL2 in airway epithelial cells and CXCL12 in fibroblasts

scientific article published on 24 April 2019

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