List of works - Nicolas Degauque

A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.

scientific article published on 28 January 2015

A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice.

scientific article

AKT1 leader gene and downstream targets are involved in a rat model of kidney allograft tolerance.

scientific article

An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8(+) T cells involved in multiple sclerosis

scientific article

Analysis of the peripheral T-cell repertoire in kidney transplant patients

scientific article published on 27 October 2010

Benefits of Using CD45RA and CD28 to Investigate CD8 Subsets in Kidney Transplant Recipients

scientific article published on 28 January 2016

Blood T-cell Vbeta transcriptome in melanoma patients

scientific article

Blood T-cell receptor beta chain transcriptome in multiple sclerosis. Characterization of the T cells with altered CDR3 length distribution

scientific article published on 25 February 2004

Blood T-cell repertoire in idiopathic nephrotic syndrome recurrence following kidney transplantation.

scientific article

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

scientific article published on 2 January 2015

Characterization of antigen-specific B cells using nominal antigen-coated flow-beads

scientific article

Compartmentalization of TCR repertoire alteration during rejection of an intrabrain xenograft

scientific article

Cross-reactivity of herpesvirus-specific CD8 T cell lines toward allogeneic class I MHC molecules

scientific article

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

scholarly article

Development of CD25- regulatory T cells following heart transplantation: evidence for transfer of long-term survival

scientific article published on 01 January 2007

Effects of cyclosporine on transplant tolerance: the role of IL-2

scientific article published on 01 August 2007

Efficient Expansion of Human Granzyme B-Expressing B Cells with Potent Regulatory Properties

scientific article published on 18 September 2020

Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis

scientific article published on 28 April 2015

Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction

scientific article

Expression of miR-142-5p in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Chronic Antibody-Mediated Rejection ⬇️

scientific article published on April 5, 2013

Fate of transplanted lungs is controlled by immune cells encounter within pulmonary allografts

scientific article

Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.

scientific article

Functional compartmentalization following induction of long-term graft survival with pregraft donor-specific transfusion

scientific article published on 11 January 2007

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.

scientific article

Indirect CD4+ TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming

scientific article published in April 2009

Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts

scholarly article

Neuropathologic, phenotypic and functional analyses of Mucosal Associated Invariant T cells in Multiple Sclerosis

scientific article published on 2 April 2016

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.

scientific article published on 29 December 2006

OX40 costimulation turns off Foxp3+ Tregs.

scientific article

Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation

scientific article published on 01 February 2005

Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype

scientific article published on 9 June 2010

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients

scientific article

Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells

scientific article published on 01 September 2007

Regulatory B cells and tolerance in transplantation: from animal models to human.

scientific article published on 31 December 2013

Regulatory T Cells in Kidney Transplantation: New Directions?

scientific article

Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help.

scientific article published on 26 November 2016

Sialylation of antibodies in kidney recipients with de novo donor specific antibody, with or without antibody mediated rejection.

scientific article published on 4 November 2015

Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases.

scientific article published on 22 August 2006

Targeting CD8 T-Cell Metabolism in Transplantation

scientific article

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure

scientific article published on 12 March 2020

The blood of healthy individuals exhibits CD8 T cells with a highly altered TCR Vb repertoire but with an unmodified phenotype

scientific article

Tolerance induction in rats, using a combination of anti-CD154 and donor splenocytes, given once on the day of transplantation.

scientific article

Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties

scientific article

Unique B cell differentiation profile in tolerant kidney transplant patients

scientific article published on 13 November 2013

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant ⬇️

scientific article published on January 26, 2012

List of works by Nicolas Degauque

A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.

A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice.

AKT1 leader gene and downstream targets are involved in a rat model of kidney allograft tolerance.

An intermediate level of CD161 expression defines a novel activated, inflammatory, and pathogenic subset of CD8(+) T cells involved in multiple sclerosis

Analysis of the peripheral T-cell repertoire in kidney transplant patients

Benefits of Using CD45RA and CD28 to Investigate CD8 Subsets in Kidney Transplant Recipients

Blood T-cell Vbeta transcriptome in melanoma patients

Blood T-cell receptor beta chain transcriptome in multiple sclerosis. Characterization of the T cells with altered CDR3 length distribution

Blood T-cell repertoire in idiopathic nephrotic syndrome recurrence following kidney transplantation.

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

Characterization of antigen-specific B cells using nominal antigen-coated flow-beads

Compartmentalization of TCR repertoire alteration during rejection of an intrabrain xenograft

Cross-reactivity of herpesvirus-specific CD8 T cell lines toward allogeneic class I MHC molecules

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

Development of CD25- regulatory T cells following heart transplantation: evidence for transfer of long-term survival

Effects of cyclosporine on transplant tolerance: the role of IL-2

Efficient Expansion of Human Granzyme B-Expressing B Cells with Potent Regulatory Properties

Expanded CD8 T-cell sharing between periphery and CNS in multiple sclerosis

Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction

Expression of miR-142-5p in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Chronic Antibody-Mediated Rejection ⬇️

Fate of transplanted lungs is controlled by immune cells encounter within pulmonary allografts

Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.

Functional compartmentalization following induction of long-term graft survival with pregraft donor-specific transfusion

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.

Indirect CD4+ TH1 response, antidonor antibodies and diffuse C4d graft deposits in long-term recipients conditioned by donor antigens priming

Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts

Neuropathologic, phenotypic and functional analyses of Mucosal Associated Invariant T cells in Multiple Sclerosis

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.

OX40 costimulation turns off Foxp3+ Tregs.

Operationally tolerant and minimally immunosuppressed kidney recipients display strongly altered blood T-cell clonal regulation

Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients

Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells

Regulatory B cells and tolerance in transplantation: from animal models to human.

Regulatory T Cells in Kidney Transplantation: New Directions?

Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help.

Sialylation of antibodies in kidney recipients with de novo donor specific antibody, with or without antibody mediated rejection.

Statistical analysis of CDR3 length distributions for the assessment of T and B cell repertoire biases.

Targeting CD8 T-Cell Metabolism in Transplantation

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure

The blood of healthy individuals exhibits CD8 T cells with a highly altered TCR Vb repertoire but with an unmodified phenotype

Tolerance induction in rats, using a combination of anti-CD154 and donor splenocytes, given once on the day of transplantation.

Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties

Unique B cell differentiation profile in tolerant kidney transplant patients

Upregulation of miR-142-3p in Peripheral Blood Mononuclear Cells of Operationally Tolerant Patients with a Renal Transplant ⬇️