List of works - Martin Picard

'Multimorbidity' as the manifestation of network disturbances.

scientific article

3D Neuronal Mitochondrial Morphology in Axons, Dendrites, and Somata of the Aging Mouse Hippocampus

scientific article published on 27 February 2021

A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress

scientific article published on 3 February 2018

A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development.

scientific article published on August 2011

Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis

scientific article published on 10 September 2023

Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells

scientific article published on 12 May 2022

Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle.

scientific article published on 22 August 2013

Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects

scientific article published on 5 January 2018

Allostatic load and comorbidities: A mitochondrial, epigenetic, and evolutionary perspective.

scientific article

Allostatic load as a tool for monitoring physiological dysregulations and comorbidities in patients with severe mental illnesses.

scientific article

Alterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles

scientific article published on 01 December 2011

An Energetic View of Stress: Focus on Mitochondria

scientific article published on 12 January 2018

Associations between cellular aging markers and metabolic syndrome: findings from the CARDIA study.

scientific article published on 18 October 2017

Blood mitochondrial DNA copy number: What are we counting?

scientific article published in September 2021

Brain mitochondrial diversity and network organization predict anxiety-like behavior in mice

scientific article published on 2 June 2021

Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

scientific article published on 30 January 2018

Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis.

scientific article published on 30 April 2016

Cross-species metabolomic analysis of tau- and DDT-related toxicity

scientific article published on 01 May 2022

Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease

scientific article published in March 2024

Deep rest: An integrative model of how contemplative practices combat stress and enhance the body's restorative capacity

scientific article published in January 2024

Depression, telomeres and mitochondrial DNA: between- and within-person associations from a 10-year longitudinal study

scientific article published on 28 March 2017

Disentangling (Epi)Genetic and Environmental Contributions to the Mitochondrial 3243A>G Mutation Phenotype: Phenotypic Destiny in Mitochondrial Disease?

scientific article published on 01 August 2016

Energy transduction and the mind–mitochondria connection

scientific article published in August 2022

Evidence Suggesting Absence of Mitochondrial DNA Methylation

scientific article published in November 2017

Expanding Our Understanding of mtDNA Deletions.

scientific article published in July 2016

Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle

scientific article published on 18 February 2016

Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system.

scientific article published on 17 June 2016

Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder

scientific article

Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transduction

scientific article published on 29 December 2022

Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts

scientific article published on 12 June 2019

Hypermetabolism and energetic constraints in mitochondrial disorders

scientific article published on 9 February 2024

In vivo microscopy reveals extensive embedding of capillaries within the sarcolemma of skeletal muscle fibers

scientific article

Independent impacts of aging on mitochondrial DNA quantity and quality in humans.

scientific article published on 21 November 2017

Leukocyte cytokine responses in adult patients with mitochondrial DNA defects

scientific article published in June 2022

Leukocyte cytokine responses in adult patients with mitochondrial DNA defects

scientific article published on 16 December 2021

Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging ⬇️

scientific article published on March 1, 2013

Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm

scientific article published on 12 March 2015

Mechanisms of Chronic Muscle Wasting and Dysfunction After an Intensive Care Unit Stay: A Pilot Study

scientific article

MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva

scientific article published in July 2023

Mitochondria impact brain function and cognition.

scientific article published on 23 December 2013

Mitochondria: isolation, structure and function.

scientific article published on 27 June 2011

Mitochondria: starving to reach quorum?: Insight into the physiological purpose of mitochondrial fusion

scientific article published on 30 January 2012

Mitochondrial DNA 3243A>G heteroplasmy is associated with changes in cytoskeletal protein expression and cell mechanics.

scientific article published on June 2017

Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons.

scientific article published on 25 November 2015

Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.

scientific article published on 25 June 2015

Mitochondrial Nanotunnels

scientific article

Mitochondrial Nexus to Allostatic Load Biomarkers.

scientific article published in January 2017

Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids.

scientific article published on 25 March 2014

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

scientific article published on 27 June 2018

Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation.

scientific article

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

scientific article published on 21 February 2017

Mitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium.

scientific article

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

scientific article published on 01 December 2010

Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal function.

scientific article published on 26 October 2011

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress

scientific article

Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice

scientific article

Mitochondrial morphology transitions and functions: implications for retrograde signaling?

scientific article published on 30 January 2013

Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study

scientific article published on 25 October 2012

Mitochondrial structure and function are disrupted by standard isolation methods

scientific article

Mitochondrial synapses: intracellular communication and signal integration.

scientific article published on 15 July 2015

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

scientific article published in April 2023

Multilevel heterogeneity of mitochondrial respiratory chain deficiency

scientific article published on 25 September 2018

Neurodegenerative disorders, metabolic icebergs, and mitohormesis

scientific article published on 6 September 2024

Nonparametric k -Sample Test on Shape Spaces with Applications to Mitochondrial Shape Analysis

scientific article published in January 2022

Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences.

scientific article

Perceived association of mood and symptom severity in adults with mitochondrial diseases

scientific article published on 4 February 2024

Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies

scientific article published on 20 December 2022

Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies

scientific article published on 6 June 2022

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

scientific article

Protective role of Parkin in skeletal muscle contractile and mitochondrial function

scientific article published on 22 April 2018

Psychological Stress and Mitochondria: A Conceptual Framework.

scientific article published in February 2018

Psychological Stress and Mitochondria: A Systematic Review.

scientific article published in February 2018

Relationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction.

scientific article published in June 2015

Reply

scientific article published on 14 March 2018

Resistance to Ca2+-induced opening of the permeability transition pore differs in mitochondria from glycolytic and oxidative muscles

scientific article published on 21 May 2008

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

scientific article published on 22 August 2024

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle

Taurine deficiency as a driver of aging

scientific article published on 08 June 2023

The Brain-body Energy Conservation Model of Aging

scientific article published on 24 November 2023

The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy.

scientific article published on 10 August 2016

The ageing neuromuscular system and sarcopenia: a mitochondrial perspective.

scientific article published on 27 February 2016

The biology of human hair greying

scientific article published on 23 September 2020

The brain–body energy conservation model of aging

scientific article published on 8 October 2024

The need for a trans-disciplinary, global health framework.

scientific article published on 10 February 2011

The rise of mitochondria in medicine

scientific article

The trajectory of life. Decreasing physiological network complexity through changing fractal patterns

scientific article published on 2 June 2015

Trans-mitochondrial coordination of cristae at regulated membrane junctions

scientific article

Why Do We Care More About Disease than Health?

scientific article published in June 2022

List of works by Martin Picard

'Multimorbidity' as the manifestation of network disturbances.

3D Neuronal Mitochondrial Morphology in Axons, Dendrites, and Somata of the Aging Mouse Hippocampus

A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress

A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development.

Accelerated physiology and increased energy expenditure in animals and humans with mitochondrial defects: A meta-analysis

Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells

Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle.

Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects

Allostatic load and comorbidities: A mitochondrial, epigenetic, and evolutionary perspective.

Allostatic load as a tool for monitoring physiological dysregulations and comorbidities in patients with severe mental illnesses.

Alterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles

An Energetic View of Stress: Focus on Mitochondria

Associations between cellular aging markers and metabolic syndrome: findings from the CARDIA study.

Blood mitochondrial DNA copy number: What are we counting?

Brain mitochondrial diversity and network organization predict anxiety-like behavior in mice

Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis.

Cross-species metabolomic analysis of tau- and DDT-related toxicity

Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease

Deep rest: An integrative model of how contemplative practices combat stress and enhance the body's restorative capacity

Depression, telomeres and mitochondrial DNA: between- and within-person associations from a 10-year longitudinal study

Disentangling (Epi)Genetic and Environmental Contributions to the Mitochondrial 3243A>G Mutation Phenotype: Phenotypic Destiny in Mitochondrial Disease?

Energy transduction and the mind–mitochondria connection

Evidence Suggesting Absence of Mitochondrial DNA Methylation

Expanding Our Understanding of mtDNA Deletions.

Failed upregulation of TFAM protein and mitochondrial DNA in oxidatively deficient fibers of chronic obstructive pulmonary disease locomotor muscle

Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system.

Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder

Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transduction

Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts

Hypermetabolism and energetic constraints in mitochondrial disorders

In vivo microscopy reveals extensive embedding of capillaries within the sarcolemma of skeletal muscle fibers

Independent impacts of aging on mitochondrial DNA quantity and quality in humans.

Leukocyte cytokine responses in adult patients with mitochondrial DNA defects

Leukocyte cytokine responses in adult patients with mitochondrial DNA defects

Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging ⬇️

Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm

Mechanisms of Chronic Muscle Wasting and Dysfunction After an Intensive Care Unit Stay: A Pilot Study

MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva

Mitochondria impact brain function and cognition.

Mitochondria: isolation, structure and function.

Mitochondria: starving to reach quorum?: Insight into the physiological purpose of mitochondrial fusion

Mitochondrial DNA 3243A>G heteroplasmy is associated with changes in cytoskeletal protein expression and cell mechanics.

Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons.

Mitochondrial DNA copy number is reduced in male combat veterans with PTSD.

Mitochondrial Nanotunnels

Mitochondrial Nexus to Allostatic Load Biomarkers.

Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids.

Mitochondrial dynamics in adaptive and maladaptive cellular stress responses

Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation.

Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

Mitochondrial function in permeabilized cardiomyocytes is largely preserved in the senescent rat myocardium.

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

Mitochondrial functional specialization in glycolytic and oxidative muscle fibers: tailoring the organelle for optimal function.

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress

Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice

Mitochondrial morphology transitions and functions: implications for retrograde signaling?

Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy study

Mitochondrial structure and function are disrupted by standard isolation methods

Mitochondrial synapses: intracellular communication and signal integration.

Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction

Multilevel heterogeneity of mitochondrial respiratory chain deficiency

Neurodegenerative disorders, metabolic icebergs, and mitohormesis

Nonparametric k -Sample Test on Shape Spaces with Applications to Mitochondrial Shape Analysis

Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences.

Perceived association of mood and symptom severity in adults with mitochondrial diseases

Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies

Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies

Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming

Protective role of Parkin in skeletal muscle contractile and mitochondrial function

Psychological Stress and Mitochondria: A Conceptual Framework.

Psychological Stress and Mitochondria: A Systematic Review.

Relationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction.

Reply

Resistance to Ca2+-induced opening of the permeability transition pore differs in mitochondria from glycolytic and oxidative muscles

Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle

Taurine deficiency as a driver of aging

The Brain-body Energy Conservation Model of Aging