List of works - Ikuo Tsunoda

A comparative study of acute and chronic diseases induced by two subgroups of Theiler's murine encephalomyelitis virus.

scientific article published in January 1996

Altered cell growth and morphology in a BHK-21 cell mutant that lacks a receptor for Theiler's murine encephalomyelitis virus.

scientific article published on March 2002

Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers

scientific article

Antiviral CD8⁺ T cells cause an experimental autoimmune encephalomyelitis-like disease in naive mice.

scientific article published on 27 January 2012

Axonal injury heralds virus-induced demyelination.

scientific article published on April 2003

Bioinformatics multivariate analysis determined a set of phase-specific biomarker candidates in a novel mouse model for viral myocarditis

scientific article

Blood circulating microparticle species in relapsing-remitting and secondary progressive multiple sclerosis. A case-control, cross sectional study with conventional MRI and advanced iron content imaging outcomes

scientific article

CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon.

scientific article published on 13 December 2017

Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection

scientific article

Contrasting roles for Valpha14+ natural killer T cells in a viral model for multiple sclerosis.

scientific article published on 27 December 2008

Converting relapsing remitting to secondary progressive experimental allergic encephalomyelitis (EAE) by ultraviolet B irradiation

scientific article published on 29 December 2004

Cross-reactive myelin antibody induces renal pathology.

scientific article

Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces

scientific article published on 03 December 2021

Distinct kinetics of viral replication, T cell infiltration, and fibrosis in three phases of myocarditis following Theiler's virus infection

scientific article

Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10.

scientific article published on February 2004

Heat shock protein 27 promotes cell cycle progression by down-regulating E2F transcription factor 4 and retinoblastoma family protein p130

scientific article published on 30 August 2018

Heterogeneity versus homogeneity of multiple sclerosis

scientific article

IFN-gamma production and astrocyte recognition by autoreactive T cells induced by Theiler's virus infection: role of viral strains and capsid proteins.

scientific article published on 20 December 2005

IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice.

scientific article published on 23 November 2016

Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease

scientific article published on 9 March 2012

Immunopathological patterns from EAE and Theiler's virus infection: Is multiple sclerosis a homogenous 1-stage or heterogenous 2-stage disease?

scientific article

Immunoregulation of Theiler's virus-induced demyelinating disease by glatiramer acetate without suppression of antiviral immune responses.

scientific article published on 23 January 2018

Induction of autoreactive CD8+ cytotoxic T cells during Theiler's murine encephalomyelitis virus infection: implications for autoimmunity.

scientific article

Infectious RNA isolated from the spinal cords of mice chronically infected with Theiler's murine encephalomyelitis virus.

scientific article published on 27 September 2006

Inflammation induces neuro-lymphatic protein expression in multiple sclerosis brain neurovasculature

scientific article published on 14 October 2013

Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination

scientific article

Lipopeptide particles as the immunologically active component of CTL inducing vaccines

scientific article published on 01 February 1999

Lymphatic system and gut microbiota affect immunopathology of neuroinflammatory diseases, including multiple sclerosis, neuromyelitis optica and Alzheimer's disease

scientific article published on 22 August 2017

Massive apoptosis in lymphoid organs in animal models for primary and secondary progressive multiple sclerosis

scientific article

Modulation of Immune System Function by Measles Virus Infection. II. Infection of B Cells Leads to the Production of a Soluble Factor That Arrests Uninfected B Cells in G0/G1 ⬇️

scientific article published on January 1, 2003

Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade

scientific article

Monoclonal MOG-reactive autoantibody from progressive EAE has the characteristics of a natural antibody.

scientific article

Multiple sclerosis and virus induced immune responses: autoimmunity can be primed by molecular mimicry and augmented by bystander activation

scientific article

Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27-Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin

scientific article published on 2 March 2018

Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures.

scientific article

Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosis

scientific article

Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection.

scientific article published in January 1998

Organ-specific protective role of NKT cells in virus-induced inflammatory demyelination and myocarditis depends on mouse strain

scientific article

Peripheral nerve protein, P0, as a potential receptor for Theiler's murine encephalomyelitis virus.

scientific article

Polyreactive myelin oligodendrocyte glycoprotein antibodies: Implications for systemic autoimmunity in progressive experimental autoimmune encephalomyelitis.

scientific article published on 2 January 2007

Possible role of interleukin-17 in a prime/challenge model of multiple sclerosis ⬇️

scientific article published on September 19, 2012

Prolonged gray matter disease without demyelination caused by Theiler's murine encephalomyelitis virus with a mutation in VP2 puff B.

scientific article

Protective and detrimental roles for regulatory T cells in a viral model for multiple sclerosis

scientific article

Purkinje Cell Death After Uptake of Anti-Yo Antibodies in Cerebellar Slice Cultures ⬇️

scientific article published on October 1, 2010

RORγt, but not T-bet, overexpression exacerbates an autoimmune model for multiple sclerosis

scientific article

Regulation of an autoimmune model for multiple sclerosis in Th2-biased GATA3 transgenic mice

scientific article published on 23 January 2014

Regulatory T cells and Th17 cells in viral infections: implications for multiple sclerosis and myocarditis

scientific article

Replacement of Loop II of VP1 of the DA Strain with Loop II of the GDVII Strain of Theiler’s Murine Encephalomyelitis Virus Alters Neurovirulence, Viral Persistence, and Demyelination ⬇️

scientific article published on September 1, 1998

Resveratrol exacerbates both autoimmune and viral models of multiple sclerosis

scientific article published on October 2013

Role of B:T cell ratio in suppression of clinical signs: a model for silent MS

scientific article published on 08 April 2008

Role of CD5+ B-1 cells in EAE pathogenesis.

scientific article

Studies in the modulation of experimental autoimmune encephalomyelitis.

scientific article

Targeting inflammatory demyelinating lesions to sites of Wallerian degeneration.

scientific article

Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis.

scientific article

Th17-biased RORγt transgenic mice become susceptible to a viral model for multiple sclerosis

scientific article

The importance of NAD in multiple sclerosis

scientific article published on January 2009

Theiler's virus infection: Pathophysiology of demyelination and neurodegeneration.

scientific article

Therapeutic evaluation of ex vivo-generated versus natural regulatory T-cells in a mouse model of chronic gut inflammation.

scientific article published on October 2013

Three immune-mediated disease models induced by Theiler's virus: Multiple sclerosis, seizures and myocarditis

scientific article

Venous endothelial injury in central nervous system diseases

scientific article

Viruses can silently prime for and trigger central nervous system autoimmune disease

scientific article published on 01 June 2001

List of works by Ikuo Tsunoda

A comparative study of acute and chronic diseases induced by two subgroups of Theiler's murine encephalomyelitis virus.

Altered cell growth and morphology in a BHK-21 cell mutant that lacks a receptor for Theiler's murine encephalomyelitis virus.

Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers

Antiviral CD8⁺ T cells cause an experimental autoimmune encephalomyelitis-like disease in naive mice.

Axonal injury heralds virus-induced demyelination.

Bioinformatics multivariate analysis determined a set of phase-specific biomarker candidates in a novel mouse model for viral myocarditis

Blood circulating microparticle species in relapsing-remitting and secondary progressive multiple sclerosis. A case-control, cross sectional study with conventional MRI and advanced iron content imaging outcomes

CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon.

Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection

Contrasting roles for Valpha14+ natural killer T cells in a viral model for multiple sclerosis.

Converting relapsing remitting to secondary progressive experimental allergic encephalomyelitis (EAE) by ultraviolet B irradiation

Cross-reactive myelin antibody induces renal pathology.

Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces

Distinct kinetics of viral replication, T cell infiltration, and fibrosis in three phases of myocarditis following Theiler's virus infection

Distinct roles for IP-10/CXCL10 in three animal models, Theiler's virus infection, EAE, and MHV infection, for multiple sclerosis: implication of differing roles for IP-10.

Heat shock protein 27 promotes cell cycle progression by down-regulating E2F transcription factor 4 and retinoblastoma family protein p130

Heterogeneity versus homogeneity of multiple sclerosis

IFN-gamma production and astrocyte recognition by autoreactive T cells induced by Theiler's virus infection: role of viral strains and capsid proteins.

IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice.

Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease

Immunopathological patterns from EAE and Theiler's virus infection: Is multiple sclerosis a homogenous 1-stage or heterogenous 2-stage disease?

Immunoregulation of Theiler's virus-induced demyelinating disease by glatiramer acetate without suppression of antiviral immune responses.

Induction of autoreactive CD8+ cytotoxic T cells during Theiler's murine encephalomyelitis virus infection: implications for autoimmunity.

Infectious RNA isolated from the spinal cords of mice chronically infected with Theiler's murine encephalomyelitis virus.

Inflammation induces neuro-lymphatic protein expression in multiple sclerosis brain neurovasculature

Inside-Out versus Outside-In models for virus induced demyelination: axonal damage triggering demyelination

Lipopeptide particles as the immunologically active component of CTL inducing vaccines

Lymphatic system and gut microbiota affect immunopathology of neuroinflammatory diseases, including multiple sclerosis, neuromyelitis optica and Alzheimer's disease

Massive apoptosis in lymphoid organs in animal models for primary and secondary progressive multiple sclerosis

Modulation of Immune System Function by Measles Virus Infection. II. Infection of B Cells Leads to the Production of a Soluble Factor That Arrests Uninfected B Cells in G0/G1 ⬇️

Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade

Monoclonal MOG-reactive autoantibody from progressive EAE has the characteristics of a natural antibody.

Multiple sclerosis and virus induced immune responses: autoimmunity can be primed by molecular mimicry and augmented by bystander activation

Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27-Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin

Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures.

Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosis

Nitric oxide synthase inhibitor, aminoguanidine, reduces inflammation and demyelination produced by Theiler's virus infection.

Organ-specific protective role of NKT cells in virus-induced inflammatory demyelination and myocarditis depends on mouse strain

Peripheral nerve protein, P0, as a potential receptor for Theiler's murine encephalomyelitis virus.

Polyreactive myelin oligodendrocyte glycoprotein antibodies: Implications for systemic autoimmunity in progressive experimental autoimmune encephalomyelitis.

Possible role of interleukin-17 in a prime/challenge model of multiple sclerosis ⬇️

Prolonged gray matter disease without demyelination caused by Theiler's murine encephalomyelitis virus with a mutation in VP2 puff B.

Protective and detrimental roles for regulatory T cells in a viral model for multiple sclerosis

Purkinje Cell Death After Uptake of Anti-Yo Antibodies in Cerebellar Slice Cultures ⬇️

RORγt, but not T-bet, overexpression exacerbates an autoimmune model for multiple sclerosis

Regulation of an autoimmune model for multiple sclerosis in Th2-biased GATA3 transgenic mice

Regulatory T cells and Th17 cells in viral infections: implications for multiple sclerosis and myocarditis

Replacement of Loop II of VP1 of the DA Strain with Loop II of the GDVII Strain of Theiler’s Murine Encephalomyelitis Virus Alters Neurovirulence, Viral Persistence, and Demyelination ⬇️

Resveratrol exacerbates both autoimmune and viral models of multiple sclerosis

Role of B:T cell ratio in suppression of clinical signs: a model for silent MS

Role of CD5+ B-1 cells in EAE pathogenesis.

Studies in the modulation of experimental autoimmune encephalomyelitis.

Targeting inflammatory demyelinating lesions to sites of Wallerian degeneration.

Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis.

Th17-biased RORγt transgenic mice become susceptible to a viral model for multiple sclerosis

The importance of NAD in multiple sclerosis

Theiler's virus infection: Pathophysiology of demyelination and neurodegeneration.

Therapeutic evaluation of ex vivo-generated versus natural regulatory T-cells in a mouse model of chronic gut inflammation.

Three immune-mediated disease models induced by Theiler's virus: Multiple sclerosis, seizures and myocarditis

Venous endothelial injury in central nervous system diseases

Viruses can silently prime for and trigger central nervous system autoimmune disease