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List of works by John Postlethwait

"Wrecks of Ancient Life": Genetic Variants Vetted by Natural Selection

scientific article

A Genetic Map for the Only Self-Fertilizing Vertebrate

scientific article published on 10 February 2016

A Hormone That Lost Its Receptor: Anti-Müllerian Hormone (AMH) in Zebrafish Gonad Development and Sex Determination

scientific article published on 09 August 2019

A RAD-tag genetic map for the platyfish (Xiphophorus maculatus) reveals mechanisms of karyotype evolution among teleost fish

scientific article

A Search for Sex-Linked Loci in the Agamid Lizard, Calotes versicolor

scientific article published on 28 June 2019

A Y-linked anti-Müllerian hormone type-II receptor is the sex-determining gene in ayu, Plecoglossus altivelis

scientific article published on 26 August 2021

A medaka gene map: the trace of ancestral vertebrate proto-chromosomes revealed by comparative gene mapping

scientific article published on 12 April 2004

A new model army: Emerging fish models to study the genomics of vertebrate Evo-Devo

scientific article

A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development

scientific article published on 2 February 2005

A zebrafish sox9 gene required for cartilage morphogenesis.

scientific article

Adaptation of Proteins to the Cold in Antarctic Fish: A Role for Methionine?

article

An SP1-like transcription factor Spr2 acts downstream of Fgf signaling to mediate mesoderm induction

scientific article published on November 17, 2003

An ancient truncated duplication of the anti‐Müllerian hormone receptor type 2 gene is a potential conserved master sex determinant in the Pangasiidae catfish family

scientific article published in 2022

An interview with John Postlethwait, Ph.D. Interview by Vicki Glaser

scientific article published in January 2004

An intestinal cell type in zebrafish is the nexus for the SARS-CoV-2 receptor and the Renin-Angiotensin-Aldosterone System that contributes to COVID-19 comorbidities

scientific article published on 02 September 2020

Ancient origin of lubricated joints in bony vertebrates

scientific article published on 19 July 2016

Antarctic blackfin icefish genome reveals adaptations to extreme environments

scientific article published on 25 February 2019

Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish Model

scientific article published in Scientific Reports

Automated analysis of conserved syntenies for the zebrafish genome

scientific article published on 01 January 2004

Automated identification of conserved synteny after whole-genome duplication

scientific article published on 22 May 2009

BAC Recombineering of the Agouti Loci from Spotted Gar and Zebrafish Reveals the Evolutionary Ancestry of Dorsal-Ventral Pigment Asymmetry in Fish

scientific article

Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes

Bone microstructure and bone mineral density are not systemically different in Antarctic icefishes and related Antarctic notothenioids

scientific article published on 22 August 2021

Brain of the blind: transcriptomics of the golden-line cavefish brain

scientific article published on 12 January 2018

Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development

scientific article published on 2 December 2002

Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency.

scientific article published in May 2003

Characterization and Evolution of the Spotted Gar Retina

scientific article published on 9 November 2016

Characterization and expression pattern of zebrafish Anti-Müllerian hormone (Amh) relative to sox9a, sox9b, and cyp19a1a, during gonad development

scientific article published on 19 April 2005

Characterization and husbandry of wild broodstock of the blackfin icefish Chaenocephalus aceratus (Lönnberg 1906) from the Palmer Archipelago (Southern Ocean) for breeding purposes

scholarly article by Nathalie R Le François published in July 2017

Characterization of a Y-specific duplication/insertion of the anti-Mullerian hormone type II receptor gene based on a chromosome-scale genome assembly of yellow perch, Perca flavescens

scientific article published on 27 January 2020

Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development

scientific article published on 30 January 2006

Characterization of the retinoic acid receptor genes raraa, rarab and rarg during zebrafish development

scientific article published on 7 February 2006

Chromosomal organization, evolutionary relationship, and expression of zebrafish GnRH family members

scientific article published on 10 November 2005

Circadian modulation of dopamine levels and dopaminergic neuron development contributes to attention deficiency and hyperactive behavior

scientific article

Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling

scientific article published in August 2003

Cloning, structural characterization and functional expression of a zebrafish bradykinin B2-related receptor.

scientific article

Cold Fusion: Massive Karyotype Evolution in the Antarctic Bullhead Notothen Notothenia coriiceps

scientific article

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery

scientific article

Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactions

scientific article published on 8 January 2018

Connectivity of vertebrate genomes: Paired-related homeobox (Prrx) genes in spotted gar, basal teleosts, and tetrapods

scientific article

Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes

scientific article

Conserved function of caspase-8 in apoptosis during bony fish evolution.

scientific article

Conserved synteny and the zebrafish genome

scientific article published in January 2011

Coordinated patterning of zebrafish caudal fin symmetry by a central and two peripheral organizers

scientific article published on 11 April 2022

Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons.

scientific article published in May 2016

Deep conservation of wrist and digit enhancers in fish

scientific article

Development of a chordate anterior-posterior axis without classical retinoic acid signaling

scientific article

Development of cuticular patterns in the legs of a cell lethal mutant ofDrosophila melanogaster

scientific article published on 01 March 1978

Development of the central nervous system in the larvacean Oikopleura dioica and the evolution of the chordate brain

scientific article

Developmental genetic basis for the evolution of pelvic fin loss in the pufferfish Takifugu rubripes

scientific article published in May 2005

Developmental roles of pufferfish Hox clusters and genome evolution in ray-fin fish

scientific article

Developmental timing of perchlorate exposure alters threespine stickleback dermal bone.

scientific article published on 6 March 2015

Developmental timing of sodium perchlorate exposure alters angiogenesis, thyroid follicle proliferation and sexual maturation in stickleback

scientific article published on 9 April 2015

Differentially-expressed opsin genes identified in Sinocyclocheilus cavefish endemic to China

scientific article published on April 2013

Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements

scientific article published in September 2004

Duplicated zebrafish co-orthologs of parathyroid hormone-related peptide (PTHrP, Pthlh) play different roles in craniofacial skeletogenesis

scientific article published on 03 July 2012

Duplication and divergence of fgf8 functions in teleost development and evolution

scientific article published in December 2007

Dynamic Evolution of the LPS-Detoxifying Enzyme Intestinal Alkaline Phosphatase in Zebrafish and Other Vertebrates

scientific article published on October 12, 2012

EML1 (CNG-modulin) controls light sensitivity in darkness and under continuous illumination in zebrafish retinal cone photoreceptors

scientific article

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Embryogenesis and early skeletogenesis in the antarctic bullhead notothen, Notothenia coriiceps.

scientific article

Endocrine disruption and differential gene expression in sentinel fish on St. Lawrence Island, Alaska: Health implications for indigenous residents.

scientific article published on 25 November 2017

Epigenetic factors Dnmt1 and Uhrf1 coordinate intestinal development

scientific article published on 05 August 2019

Erratum: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

scientific article published in Nature

Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates.

scientific article

Evolution after Whole-Genome Duplication: Teleost MicroRNAs

scientific article published on 01 July 2021

Evolution and development of facial bone morphology in threespine sticklebacks.

scientific article

Evolution of caudal fin ray development and caudal fin hypural diastema complex in spotted gar, teleosts, and other neopterygian fishes.

scientific article published on 22 March 2018

Evolution of developmental regulation in the vertebrate FgfD subfamily

scientific article

Evolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages

scientific article

Evolution of gene expression after whole-genome duplication: New insights from the spotted gar genome.

scientific article

Evolution of sarcomeric myosin heavy chain genes: evidence from fish

scientific article

Evolution of the Eye Transcriptome under Constant Darkness in Sinocyclocheilus Cavefish.

scientific article published on 13 September 2013

Evolution of the eye transcriptome under constant darkness in Sinocyclocheilus cavefish

scientific article

Evolution of the miR199-214 cluster and vertebrate skeletal development

scientific article (publication date: 2014)

Evolution of the osteoblast: skeletogenesis in gar and zebrafish

scientific article (publication date: 5 March 2012)

Evolution of the thyroid: anterior-posterior regionalization of the Oikopleura endostyle revealed by Otx, Pax2/5/8, and Hox1 expression

scientific article published in May 2008

Evolution of the vertebrate pth2 (tip39) gene family and the regulation of PTH type 2 receptor (pth2r) and its endogenous ligand pth2 by hedgehog signaling in zebrafish development

scientific article published on August 31, 2011

Evolutionary Origin and Nomenclature of Vertebrate Wnt11-Family Genes

scientific article published on 11 July 2019

Evolutionary developmental biology and genomics

scientific article

Evolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleosts

scientific article

Evolutionary mutant models for human disease

scientific article

Evolutionary mutant models for human disease

article

Exogenous iodide ameliorates perchlorate-induced thyroid phenotypes in threespine stickleback

scientific article published in November 2016

Expanding the annotation of zebrafish microRNAs based on small RNA sequencing

scientific article published on 15 May 2014

Expression Signatures of Cisplatin- and Trametinib-Treated Early-Stage Medaka Melanomas

scientific article published on 09 July 2019

Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation

scientific article published on 13 January 2009

Expression signatures of early-stage and advanced medaka melanomas

scientific article published on 18 November 2017

Eye Degeneration and Loss of otx5b Expression in the Cavefish Sinocyclocheilus tileihornes

scientific article published on 22 July 2019

FGF-receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9.

scientific article published on January 2010

Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish

scientific article published on 16 November 2018

Female-specific increase in primordial germ cells marks sex differentiation in threespine stickleback (Gasterosteus aculeatus).

scientific article published in August 2008

Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification

scientific article published in May 2003

Foxl2 and Its Relatives Are Evolutionary Conserved Players in Gonadal Sex Differentiation

scientific article

Gene duplication, gene loss and evolution of expression domains in the vertebrate nuclear receptor NR5A (Ftz-F1) family

scientific article published on July 2005

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database

scientific article

Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization model

article

Genome Evolution and Meiotic Maps by Massively Parallel DNA Sequencing: Spotted Gar, an Outgroup for the Teleost Genome Duplication

scientific article (publication date: August 2011)

Genome duplication, subfunction partitioning, and lineage divergence:Sox9in stickleback and zebrafish

scientific article published on November 1, 2003

Genomic conservation of erythropoietic microRNAs (erythromiRs) in white-blooded Antarctic icefish.

scientific article published on 14 May 2016

Genomics of cold adaptations in the Antarctic notothenioid fish radiation

scientific article published in 2023

Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma models

scientific article

Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish

scientific article

Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton

scientific article

Hox cluster organization in the jawless vertebrate Petromyzon marinus

scientific article

Hoxb1b controls oriented cell division, cell shape and microtubule dynamics in neural tube morphogenesis

scientific article

IRF2BPL Is Associated with Neurological Phenotypes

Identification and characterization of the zebrafish and fugu genes encoding tuberoinfundibular peptide 39.

scientific article published on 5 August 2004

Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish

scientific article (publication date: 2004)

Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation

scientific article published on 22 August 2019

Identification of transcriptome SNPs between Xiphophorus lines and species for assessing allele specific gene expression within F₁ interspecies hybrids

scientific article

Inferring ancestral gene order

scientific article published on January 2008

Intergeneric hybrids inform reproductive isolating barriers in the Antarctic icefish radiation

article

Is retinoic acid genetic machinery a chordate innovation?

scientific article published in September 2006

Isolation and characterization of zebrafish NFE2.

scientific article published on 29 October 2002

Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish.

scientific article published on 28 February 2017

Manganese accumulates in the brain of northern quolls (Dasyurus hallucatus) living near an active mine

scientific article

Measures of synteny conservation between species pairs

scientific article

MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis

scientific article

MicroRNA Profiling during Craniofacial Development: Potential Roles for Mir23b and Mir133b

scientific article published on 14 July 2016

MicroRNAs and micromanaging the skeleton in disease, development and evolution

scientific article

Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research

scientific article published on September 2017

Molecular evolution and functional divergence of zebrafish (Danio rerio) cryptochrome genes

scientific article

Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybrids.

scientific article published on 27 March 2017

Molecular pedomorphism underlies craniofacial skeletal evolution in Antarctic notothenioid fishes

scientific article (publication date: 6 January 2010)

Multiple independent chromosomal fusions accompanied the radiation of the Antarctic teleost genus Trematomus (Notothenioidei:Nototheniidae)

scientific article published on 20 March 2020

Multiple sex-associated regions and a putative sex chromosome in zebrafish revealed by RAD mapping and population genomics

scientific article

Mutations in fam20b and xylt1 Reveal That Cartilage Matrix Controls Timing of Endochondral Ossification by Inhibiting Chondrocyte Maturation

scientific article published on August 25, 2011

Na,K-ATPase alpha and beta subunit genes exhibit unique expression patterns during zebrafish embryogenesis.

scientific article published in August 2002

Neuroendocrinology of reproduction: Is gonadotropin-releasing hormone (GnRH) dispensable?

scientific article published on 22 February 2019

Observation ofmiRNAGene Expression in Zebrafish Embryos byIn SituHybridization to MicroRNA Primary Transcripts

scientific article published on February 2, 2011

Oikopleura dioica alcohol dehydrogenase class 3 provides new insights into the evolution of retinoic acid synthesis in chordates

scientific article published in February 2010

One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology

scientific article

Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution

scientific article

Parallel genetic basis for repeated evolution of armor loss in Alaskan threespine stickleback populations.

scholarly article

Pattern formation in the wing and haltere imaginal discs after irradiation ofDrosophila melanogaster first instar larvae

scientific article published on 01 March 1975

Perchlorate Exposure Reduces Primordial Germ Cell Number in Female Threespine Stickleback

scientific article

Perchlorate disrupts embryonic androgen synthesis and reproductive development in threespine stickleback without changing whole-body levels of thyroid hormone.

scientific article

Perchlorate exposure does not modulate temporal variation of whole-body thyroid and androgen hormone content in threespine stickleback.

scientific article published on 27 February 2015

Pharyngeal morphogenesis requires fras1-itga8-dependent epithelial-mesenchymal interaction

scientific article published on 2 June 2016

Phylogeny of zebrafish, a "model species," within Danio, a "model genus"

scientific article

Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate

scientific article (publication date: 3 December 2010)

Polyploidy in Fish and the Teleost Genome Duplication

Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway.

scientific article

RAD marker microarrays enable rapid mapping of zebrafish mutations

scientific article published on January 2007

Reply to: 'Subfunctionalization versus neofunctionalization after whole-genome duplication'

scientific article published on 01 July 2018

Retinoic acid metabolic genes, meiosis, and gonadal sex differentiation in zebrafish

scientific article

Roles of brca2 (fancd1) in oocyte nuclear architecture, gametogenesis, gonad tumors, and genome stability in zebrafish

scientific article (publication date: March 2011)

Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis.

scientific article

Runx3 is required for hematopoietic development in zebrafish

scientific article

SCPP Genes and Their Relatives in Gar: Rapid Expansion of Mineralization Genes in Osteichthyans.

scientific article published on 22 June 2017

Seeing chordate evolution through the Ciona genome sequence

scientific article

Sex chromosome and sex locus characterization in goldfish, Carassius auratus (Linnaeus, 1758)

scientific article published on 11 August 2020

Sex reversal in zebrafish fancl mutants is caused by Tp53-mediated germ cell apoptosis

scientific article

Sex-specific recombination rates in zebrafish (Danio rerio)

scientific article

Single Nucleotide Polymorphism (SNP) Panels for Rapid Positional Cloning in Zebrafish

scientific article published on 01 January 2011

Skeletal development in the heterocercal caudal fin of spotted gar (lepisosteus oculatus) and other lepisosteiformes

scientific article published on 13 January 2018

Sox9 Is Upstream of MicroRNA-140 in Cartilage

scientific article published on November 4, 2011

Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear.

scientific article published on 15 March 2008

Stacks: Building and Genotyping Loci De Novo From Short-Read Sequences

scientific article published on August 1, 2011

Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis.

scientific article published on 30 August 2006

Studies of threespine stickleback developmental evolution: progress and promise.

scientific article published on 8 August 2006

Subfunction partitioning, the teleost radiation and the annotation of the human genome.

scientific article published in October 2004

Temporally and spatially restricted gene expression profiling

scientific article

The African coelacanth genome provides insights into tetrapod evolution

scientific article

The Developmental and Genetic Architecture of the Sexually Selected Male Ornament of Swordtails

scientific article published on 02 December 2020

The FaceBase Consortium: a comprehensive program to facilitate craniofacial research

scientific article

The Fanconi anemia gene network is conserved from zebrafish to human.

scientific article

The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics.

scientific article published on 03 December 2008

The Molecular Evolution of Circadian Clock Genes in Spotted Gar (Lepisosteus oculatus)

scientific article published on 17 August 2019

The Role of Fanconi Anemia/BRCA Genes in Zebrafish Sex Determination

scientific article published on January 1, 2011

The Spotted Gar: Genomic Journeys into a Lost World

scientific article published in November 2017

The evolutionary history of placodes: a molecular genetic investigation of the larvacean urochordate Oikopleura dioica

scientific article published on 24 August 2005

The gene history of zebrafish tlr4a and tlr4b is predictive of their divergent functions.

scientific article

The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination system

scientific article published on 28 March 2019

The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits

scientific article

The genome sequence of the Antarctic bullhead notothen reveals evolutionary adaptations to a cold environment

scientific article

The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC.

scientific article published on 28 February 2006

The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish

scientific article

The rise and fall of the ancient northern pike master sex determining gene

scientific article published in June 2020

The role of a retinoic acid response element in establishing the anterior neural expression border of Hoxd4 transgenes.

scientific article published in March 2003

The role of stat1b in zebrafish hematopoiesis

scientific article published on 3 September 2011

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

scientific article

The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization

scientific article published on 30 March 2020

The teleost agouti-related protein 2 gene is an ohnolog gone missing from the tetrapod genome

scientific article published on 15 March 2011

The zebrafish gene map defines ancestral vertebrate chromosomes

scientific article published on 18 August 2005

The zebrafish genome in context: ohnologs gone missing

scientific article published on September 2007

The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development

scientific article published on June 2017

Transcriptomes of post-mitotic neurons identify the usage of alternative pathways during adult and embryonic neuronal differentiation

scientific article published on 23 December 2015

Transgene-mediated skeletal phenotypic variation in zebrafish

scientific article published on 29 February 2020

Two Na,K-ATPase beta 2 subunit isoforms are differentially expressed within the central nervous system and sensory organs during zebrafish embryogenesis

scientific article published in March 2002

Two Zebrafish hsd3b Genes Are Distinct in Function, Expression, and Evolution

scientific article published on 14 May 2015

Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish

scientific article published on October 2011

UDP xylose synthase 1 is required for morphogenesis and histogenesis of the craniofacial skeleton

scientific article

Unification of miRNA and isomiR research: the mirGFF3 format and the mirtop API

scientific article published on 01 February 2020

Variations on a theme: Genomics of sex determination in the cichlid fish Astatotilapia burtoni

scientific article

Ventralized zebrafish embryo rescue by overexpression of Zic2a

scientific article published in January 2004

Vertebrate sex-determining genes play musical chairs

scientific article

Whole Body Melanoma Transcriptome Response in Medaka

scientific article

Wild sex in zebrafish: loss of the natural sex determinant in domesticated strains

scientific article

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

scientific journal article

X. couchianus and X. hellerii genome models provide genomic variation insight among Xiphophorus species

scientific article published on 7 January 2016

Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development

scientific article published in August 2005

fgf17b, a novel member of Fgf family, helps patterning zebrafish embryos

scientific article

fras1shapes endodermal pouch 1 and stabilizes zebrafish pharyngeal skeletal development

scientific article published on August 1, 2012

miR-196 regulates axial patterning and pectoral appendage initiation

scientific article

miRNA analysis with Prost! reveals evolutionary conservation of organ-enriched expression and post-transcriptional modifications in three-spined stickleback and zebrafish

scientific article published on 08 March 2019