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List of works by John Bringas

A dose-ranging study of AAV-hAADC therapy in Parkinsonian monkeys

scientific article published on 16 June 2006

AAV viral vector delivery to the brain by shape-conforming MR-guided infusions

scientific article

Anatomic compression caused by high-volume convection-enhanced delivery to the brain

scientific article published on September 2009

Basic fibroblast growth factor enhances transduction, distribution, and axonal transport of adeno-associated virus type 2 vector in rat brain

scientific article

Biodistribution of adeno-associated virus type-2 in nonhuman primates after convection-enhanced delivery to brain

scientific article published on 03 June 2008

Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates

scientific article published on 12 January 2016

Comparison of two methods for the analysis of [18F]6-fluoro-L-m-tyrosine PET data

scientific article

Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain

scientific article published in March 2006

Design of an in-dwelling cannula for convection-enhanced delivery.

scientific article published on 25 December 2010

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

scientific article published on 17 March 2014

Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain

scientific article

Effects of the perivascular space on convection-enhanced delivery of liposomes in primate putamen

scientific article published on 16 August 2005

Efficient gene therapy-based method for the delivery of therapeutics to primate cortex

scholarly article

Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC.

scientific article

Evaluation of pressure‐driven brain infusions in nonhuman primates by intra‐operative 7 tesla MRI ⬇️

scientific article published on August 7, 2012

Focal striatal dopamine may potentiate dyskinesias in parkinsonian monkeys

scientific article published on 09 December 2005

Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys

scientific article published on May 2009

Image-guided convection-enhanced delivery of GDNF protein into monkey putamen

scientific article

Invasive phenotype observed in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant sublines of 9L rat glioma cells: a tumor model mimicking a recurrent malignant glioma

scientific article

Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC.

scientific article published on 7 July 2006

MRI-Guided Delivery of Viral Vectors

scientific article published on January 2016

Merits of Combination Cortical, Subcortical, and Cerebellar Injections for the Treatment of Niemann-Pick Disease Type A ⬇️

scientific article published on July 24, 2012

Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates

scientific article published on 15 September 2009

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy

scientific article published on 29 March 2016

Real-time MR imaging of adeno-associated viral vector delivery to the primate brain

scientific article

Real-time MR imaging with Gadoteridol predicts distribution of transgenes after convection-enhanced delivery of AAV2 vectors

scientific article

Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging

scientific article published on 21 September 2005

Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents

scientific article

Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

scientific article

SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.

scientific article

Safety Study of Adeno-Associated Virus Serotype 2-Mediated Human Acid Sphingomyelinase Expression in the Nonhuman Primate Brain ⬇️

scientific article published on August 1, 2012

Safety and tolerability of magnetic resonance imaging-guided convection-enhanced delivery of AAV2-hAADC with a novel delivery platform in nonhuman primate striatum

scientific article published on 26 January 2012

Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys

scientific article

The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys

scientific article

Transduction of nonhuman primate brain with adeno-associated virus serotype 1: vector trafficking and immune response

scientific article published on March 2009

Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease

scientific article published on 29 June 2016

Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus.

scientific article published on 14 October 2017

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