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List of works by Thomas Klockgether

(CAG)n loci as genetic modifiers of age-at-onset in patients with Machado-Joseph disease from mainland China

scientific article published on 16 April 2016

18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor

scientific article published on 10 October 2016

51-year-old female with steroid-responsive optic neuropathy: a new case of chronic relapsing inflammatory optic neuropathy (CRION).

scientific article published on 27 June 2008

A defect of kinesthesia in Parkinson's disease

scientific article (publication date: July 1995)

A rare truncating mutation in ADH1C (G78Stop) shows significant association with Parkinson disease in a large international sample

scientific article published in January 2005

Abnormal movement preparation in task-specific focal hand dystonia

scientific article

Acute hebephrenia

scientific article published in August 2005

Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice

scientific article published on 7 April 2005

Adult index patient with Currarino syndrome due to a novel HLXB9 mutation, c.336dupG (p.P113fsX224), presenting with Hirschsprung's disease, cephalgia, and lumbodynia

scientific article published on 01 March 2007

An interleukin-6 promoter variant is not associated with an increased risk for Alzheimer's disease

scientific article published on 20 January 2004

An update on inherited ataxias

scientific article published on July 2008

Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease

scientific article published in May 2004

Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease

scientific article published on 19 April 2016

Apraxia of lid opening mimicking ptosis in compound heterozygosity for A467T and W748S POLG1 mutations

scientific article published in July 2008

Association of the PPARgamma gene polymorphism Pro12Ala with delayed onset of multiple sclerosis

scientific article

Association study of dopamine D2, D3, D4 receptor and serotonin transporter gene polymorphisms with sleep attacks in Parkinson's disease

scientific article published in June 2004

Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation

scientific journal article

Auto-Gait

scientific article published on 28 March 2023

Bcl-2 up-regulates ha-ras mRNA expression and induces c-Jun phosphorylation at Ser73 via an ERK-dependent pathway in PC 12 cells

scientific article published on December 2002

Bell's palsy: combined treatment of famciclovir and prednisone is superior to prednisone alone

scientific article

Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells

scientific article published on 28 July 2006

Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data

scientific article

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data

scientific article

Body Mass Index Decline Is Related to Spinocerebellar Ataxia Disease Progression

Brain endothelial PPARgamma controls inflammation-induced CD4+ T cell adhesion and transmigration in vitro.

scientific article published on 24 August 2007

Bright light therapy in Parkinson's disease: a pilot study

scientific article published in July 2007

Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen

scientific article

C1-inhibitor activity and plasma concentrations in patients with monoclonal gammopathies: implications for treatment with recombinant interferon-beta 1b.

scientific article published in April 2004

CNS infection with Chlamydia pneumoniae complicated by multiple strokes

scientific article published in September 2002

Callosal tissue loss in multiple system atrophy--a one-year follow-up study

scientific article

Central Pain Processing in Early-Stage Parkinson's Disease: A Laser Pain fMRI Study

scientific article

Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency

scientific article

Cerebral embolism from left atrial myxoma leading to cerebral and retinal aneurysms: a case report

scientific article published on March 2005

Circulating adhesion molecules in patients with internal carotid artery stenosis

scientific article published on 01 January 2002

Clinical and genetic characteristics of sporadic adult-onset degenerative ataxia

scientific article published on 09 August 2017

Cognition in Friedreich's ataxia: a behavioral and multimodal imaging study

scientific article published on 21 June 2016

Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma

scientific article published in April 2003

Common genetic coagulation variants are not associated with ischemic stroke in a case-control study

scientific article published on 5 August 2009

Comparison of three clinical rating scales in Friedreich ataxia (FRDA).

scientific article

Consensus statement on the diagnosis of multiple system atrophy

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

scientific article

Cooling improves the writing performance of patients with writer's cramp

scientific article published on November 2002

Copper deficiency associated with severe neurological disorder--a genetic work-up of possible mutations in copper transport proteins

scientific article published on 11 February 2010

Cost of illness in subarachnoid hemorrhage: a German longitudinal study

scientific article

Cost-of-illness in multiple system atrophy and progressive supranuclear palsy ⬇️

scientific article published on April 10, 2011

Cranial magnetic resonance imaging in genetically proven myotonic dystrophy type 1 and 2

scientific article published on 01 June 2004

Depression comorbidity in spinocerebellar ataxia

scientific article

Diagnostic value of mitochondrial DNA mutation analysis in juvenile unilateral ptosis

scientific article

Differentially expressed gene profile in the 6-hydroxy-dopamine-induced cell culture model of Parkinson's disease ⬇️

scientific article published on January 17, 2012

Discriminatory features of acute transverse myelitis: a retrospective analysis of 45 patients

scientific article published in February 2004

Disentangling motor planning and motor execution in unmedicated de novo Parkinson's disease patients: An fMRI study

scholarly article by Jason A Martin et al published 19 March 2019 in NeuroImage: Clinical

Disorganization of the desmin cytoskeleton and mitochondrial dysfunction in plectin-related epidermolysis bullosa simplex with muscular dystrophy

scientific article published in June 2002

Does degeneration of the subthalamic nucleus prevent parkinsonism in spinocerebellar ataxia type 2 and type 3?

scientific article published in November 2015

Dopamine transporter imaging and SPECT in diagnostic work-up of Parkinson's disease: A decision-analytic approach ⬇️

scientific article published on October 1, 2003

Dopamine transporter positron emission tomography in spinocerebellar ataxias type 1, 2, 3, and 6.

scientific article published in August 2005

Dual task effect on postural control in patients with degenerative cerebellar disorders

scientific article

Early symptoms in spinocerebellar ataxia type 1, 2, 3, and 6.

scientific article published in November 2008

Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial

scientific article

Elevated in vivo [18F]-AV-1451 uptake in a patient with progressive supranuclear palsy

scientific article

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

scientific article published on 23 November 2011

Expanded phenotype and hippocampal involvement in a novel compound heterozygosity of adult PLA2G6 associated neurodegeneration (PARK14).

scientific article published on 10 January 2017

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3 ⬇️

scientific article published on May 2, 2011

Falls in spinocerebellar ataxias: Results of the EuroSCA Fall Study

scientific article

Feature Binding Deficits in Subjective Cognitive Decline and in Mild Cognitive Impairment

scientific article published on 18 September 2015

Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice

scientific article

Friedreich and dominant ataxias: quantitative differences in cerebellar dysfunction measurements

scientific article published on 26 December 2017

Gene Expression Profiling in Ataxin-3 Expressing Cell Lines Reveals Distinct Effects of Normal and Mutant Ataxin-3 ⬇️

scientific article published on October 1, 2003

Gene dosage-dependent effects of bcl-2 expression on cellular survival and redox status

scientific article

Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy

article

Genotype-specific patterns of atrophy progression are more sensitive than clinical decline in SCA1, SCA3 and SCA6.

scientific article published on 18 February 2013

Global DNA methylation is influenced by smoking behaviour

scientific article published on 31 January 2008

Grey and white matter loss along cerebral midline structures in myotonic dystrophy type 2.

scientific article published on 03 September 2008

Health-Related Quality of Life in Multiple System Atrophy and Progressive Supranuclear Palsy ⬇️

scientific article published on May 12, 2011

Health-related quality of life in multiple system atrophy

scientific article published in June 2006

Health-related quality of life in patients with subarachnoid haemorrhage

scientific article

Health-related quality of life in sporadic adult-onset ataxia

scientific article published in February 2007

Hereditary hyper-ACE-emia due to the Pro1199Leu mutation of somatic ACE as a potential pitfall in diagnosis: a first family outside Europe

scientific article published on 01 January 2006

Hereditary spastic paraplegia: Clinicogenetic lessons from 608 patients

scientific article

Heritability of carotid artery atherosclerotic lesions: an ultrasound study in 154 families

scientific article published on 29 November 2004

High Serum GFAP Levels in SCA3/MJD May Not Correlate with Disease Progression

scientific article published on 14 April 2015

Higher sensitivity in the detection of inflammatory brain lesions in patients with clinically isolated syndromes suggestive of multiple sclerosis using high field MRI: an intraindividual comparison of 1.5 T with 3.0 T.

scientific article published on 29 April 2006

Homocysteine and carotid intima-media thickness in a german population: lack of clinical relevance

scientific article published on 28 September 2006

Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia

scientific article published on 27 April 2017

IFN-β1a (Rebif®) Modifies the Expression of Microfilament-Associated Cell-Cell Contacts in C6 Glioma Cells ⬇️

scientific article published on February 1, 2003

Imaging of inflammatory lesions at 3.0 Tesla in patients with clinically isolated syndromes suggestive of multiple sclerosis: a comparison of fluid-attenuated inversion recovery with T2 turbo spin-echo

scientific article published on 4 April 2006

Impaired sleep quality and restless legs syndrome in idiopathic focal dystonia: a controlled study ⬇️

scientific article published on April 16, 2011

In Vivo Voxel-Based Morphometry in Multiple System Atrophy of the Cerebellar Type ⬇️

scientific article published on October 1, 2003

In vivo Patterns of Tau Pathology, Amyloid-β Burden, and Neuronal Dysfunction in Clinical Variants of Alzheimer's Disease

scientific article published on 11 October 2016

In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate

scientific article published on 01 June 2006

In vivo voxel-based relaxometry in amyotrophic lateral sclerosis

scientific article published in January 2009

Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination

scientific journal article

Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1.

scientific article published on 17 June 2009

Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma

scientific article

Instability of syllable repetition in patients with spinocerebellar ataxia and Parkinson's disease

scientific article published on 22 November 2011

Intensified PCV-chemotherapy with optional stem cell support in recurrent malignant oligodendroglioma

scientific article

Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis ⬇️

scientific article published on May 1, 2003

Isolated spasticity in sporadic Creutzfeldt-Jakob disease ⬇️

scientific article published on November 16, 2012

Lack of association between the interleukin-1 alpha (-889) polymorphism and early-onset Parkinson's disease

scientific article published in April 2004

Lack of association of interleukin-10 promoter region polymorphisms with Alzheimer's disease ⬇️

scientific article published on May 15, 2003

Lack of genetic dispositions to hyperhomocysteinemia in Alzheimer disease

scientific article

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

scientific article published on 24 March 2012

Linkage and Association Analysis Identifies TRAF1 Influencing Common Carotid Intima-Media Thickness

scientific article published on 8 November 2016

Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice.

scientific article

Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model

scientific article published on 13 January 2007

Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: a longitudinal cohort study

scientific article published on 11 September 2015

Long-term evolution of patient-reported outcome measures in spinocerebellar ataxias

Milestones in ataxia ⬇️

scientific article published on May 1, 2011

Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial).

scientific article published in January 2010

Modulation of the age at onset in spinocerebellar ataxia by CAG tracts in various genes

scientific article

Molecular analysis of thrombophilic risk factors in patients with dural arteriovenous fistulas

scientific article

Motor complications in patients form the German Competence Network on Parkinson's disease and the DRD3 Ser9Gly polymorphism

scientific article

Multiple system atrophy with macrosquare-wave jerks

scientific article published on 01 February 2005

Multisystemic SYNE1 ataxia: confirming the high frequency and extending the mutational and phenotypic spectrum

scientific article published on 19 May 2016

Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism

scientific article

Neuropsychological features of patients with spinocerebellar ataxia (SCA) types 1, 2, 3, and 6.

scientific article

Neutralizing antibodies against botulinum toxin a after a wasp sting

scientific article published in December 2006

Never neglect inspecting the leg in movement disorders

scientific article published in June 2012

Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation

scientific article published in September 2011

No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors

scholarly article by Franziska Hopfner et al published 2019 in Translational Neurodegeneration

Noninvasive detection of steno-occlusive disease of the supra-aortic arteries with three-dimensional contrast-enhanced magnetic resonance angiography: a prospective, intra-individual comparative analysis with digital subtraction angiography

scientific article

Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.

scientific article published on October 2003

Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma

scientific article

Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons

scientific article published in August 2003

Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.

scientific article

Olfactory dysfunction in cerebellar ataxia and multiple system atrophy

scientific article published in December 2003

On the fast track to diagnosis : Recommendations for patients without a diagnosis

scientific article published in May 2017

Parkinson's disease: clinical aspects

scientific article published on 8 September 2004

Parkinsonism & related disorders. Ataxias

scientific article published on January 2007

Parkinson’s Disease and Dementia: A Longitudinal Study (DEMPARK)

scholarly article by Monika Balzer-Geldsetzer et al published 2011 in Neuroepidemiology

Peripheral Neuropathy in Spinocerebellar Ataxia Type 1, 2, 3, and 6.

scientific article

Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy

scientific article published on 01 February 2007

Plasma folate levels are associated with the lipoprotein profile: a retrospective database analysis

scientific article

Potassium channel dysfunction and depolarized resting membrane potential in a cell model of SCA3.

scientific article published on 12 June 2006

Prediction of the age at onset in spinocerebellar ataxia type 1, 2, 3 and 6.

scientific article

Presentation, diagnosis, and management of multiple system atrophy in Europe: final analysis of the European multiple system atrophy registry

scientific article

Primary Central Nervous System Lymphoma: Results of a Pilot and Phase II Study of Systemic and Intraventricular Chemotherapy With Deferred Radiotherapy ⬇️

scientific article published on November 3, 2003

Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 2 year cohort study

scientific article published on December 2016

Progression of multiple system atrophy (MSA): a prospective natural history study by the European MSA Study Group (EMSA SG).

scientific article

Progressive cognitive dysfunction in spinocerebellar ataxia type 3.

scientific article published on 4 June 2013

Progressive multifocal leukoencephalopathy with selective involvement of the pyramidal tracts

scientific article published on March 2007

Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients

scientific article

Qigong exercise for the symptoms of Parkinson's disease: a randomized, controlled pilot study

scientific article

REM sleep behavioral disorder in pure autonomic failure (PAF).

scientific article

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

scientific article published on 13 December 2017

Red flags for multiple system atrophy

scientific article published in June 2008

Reliability and validity of the International Cooperative Ataxia Rating Scale: a study in 156 spinocerebellar ataxia patients

scientific article

Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients

scientific article

Reply to: Cognitive dysfunction in spinocerebellar ataxia type 3: variable topographies and patterns

scientific article published on 11 December 2013

Restricted ocular exploration does not seem to explain simultanagnosia

scientific article published on 30 June 2006

Reversible multifocal leukoencephalopathy associated with a nocturnal blood pressure non-dipper pattern

scientific article published in August 2010

Saccade velocity is controlled by polyglutamine size in spinocerebellar ataxia 2.

scientific article published in September 2004

Self-rated health status in spinocerebellar ataxia--results from a European multicenter study

scientific article

Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

scientific article published on 15 September 2008

Serial MRI of limbic encephalitis

scientific article

Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease

scientific article

Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain

scientific article

Spectral analysis of heart rate variability in multiple system atrophy and unexplained sporadic ataxia

scientific article

Spinocerebellar ataxia type 2 (SCA2): identification of early brain degeneration in one monozygous twin in the initial disease stage.

scientific article

Spinocerebellar ataxia types 1, 2, 3 and 6: the clinical spectrum of ataxia and morphometric brainstem and cerebellar findings

scientific article published in March 2012

Sporadic adult-onset ataxia of unknown etiology

scientific article published on January 1, 2012

Sporadic ataxia with adult onset: classification and diagnostic criteria

scientific article

Standardized Assessment of Hereditary Ataxia Patients in Clinical Studies

State of the art review: molecular diagnosis of inherited movement disorders. Movement Disorders Society task force on molecular diagnosis

scientific article

Survival in patients with spinocerebellar ataxia types 1, 2, 3, and 6 (EUROSCA): a longitudinal cohort study

scientific article published on 13 March 2018

The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease

scientific article published on March 2008

The brain in myotonic dystrophy 1 and 2: evidence for a predominant white matter disease

scientific article

The clinical diagnosis of autosomal dominant spinocerebellar ataxias

scientific article published on 01 January 2008

The cystathionine ?-synthase (CBS) mutation c.1224-2A>C in Central Europe: Vitamin B6 nonresponsiveness and a common ancestral haplotype

scientific article published on 01 October 2004

The cystathionine beta-synthase variant c.844_845ins68 protects against CNS demyelination in X-linked adrenoleukodystrophy

scientific article published on 01 October 2006

The flavanoide caffeic acid phenethyl ester blocks 6-hydroxydopamine-induced neurotoxicity

scientific article published in July 2005

The human MJD gene: genomic structure and functional characterization of the promoter region ⬇️

scientific article published on September 18, 2003

The natural history of multiple system atrophy: a prospective European cohort study

scientific article published on 5 February 2013

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

scientific article published on 08 September 2009

The preclinical stage of spinocerebellar ataxias

scientific article published on 10 June 2015

Therapeutic prospects for spinocerebellar ataxia type 2 and 3.

scientific article

Tracking the brain in myotonic dystrophies: A 5-year longitudinal follow-up study

Transcriptional changes in multiple system atrophy and Parkinson's disease putamen

scientific article

Update of the effect estimates for common variants associated with carotid intima media thickness within four independent samples: The Bonn IMT Family Study, the Heinz Nixdorf Recall Study, the SAPHIR Study and the Bruneck Study

scientific article

Update on degenerative ataxias ⬇️

scientific article published on August 1, 2011

Variants associated with Gaucher disease in multiple system atrophy

scientific article

Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6.

scientific article published on 22 July 2009

Voxel-based analysis of multiple-system atrophy of cerebellar type: complementary results by combining voxel-based morphometry and voxel-based relaxometry

scientific article published on 16 January 2005

fMRI of global visual perception in simultanagnosia

scientific article published on 6 November 2008

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