List of works by Karlheinz Peter

A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury.

scientific article

A Unique Recombinant Fluoroprobe Targeting Activated Platelets Allows In Vivo Detection of Arterial Thrombosis and Pulmonary Embolism Using a Novel Three-Dimensional Fluorescence Emission Computed Tomography (FLECT) Technology

scientific article

A conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties

scientific article published on 20 May 2014

A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI

scientific article

A deletion in the ?? subunit locks platelet integrin ??IIb??3 into a high affinity state

A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense

scientific article

A molecular intravascular ultrasound contrast agent allows detection of activated platelets on the surface of symptomatic human plaques

scientific article published on 24 October 2017

A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling

scientific article

A proteomic analysis of C-reactive protein stimulated THP-1 monocytes

scientific article

A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

scientific article published on 2 May 2017

A versatile approach for the site-specific modification of recombinant antibodies using a combination of enzyme-mediated bioconjugation and click chemistry

scientific article published on 11 May 2015

Abciximab, eptifibatide, and tirofiban exhibit dose-dependent potencies to dissolve platelet aggregates

scientific article published on April 2003

Activated platelets in carotid artery thrombosis in mice can be selectively targeted with a radiolabeled single-chain antibody

scientific article (publication date: 2011)

Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases

scientific article published on 07 February 2019

Activated-platelet targeting of CD39 as a potential way forward. The quest for efficient antithrombotic therapy without associated bleeding complications

scientific article published on 02 September 2015

Activating effects of GPIIb/IIIa blockers: an intrinsic consequence of ligand-mimetic properties

scientific article published on 01 May 2002

Activation of platelets in young infants during cardiopulmonary bypass

scientific article published on 18 December 2009

Adhesion of monocytes to medical steel as used for vascular stents is mediated by the integrin receptor Mac-1 (CD11b/CD18; alphaM beta2) and can be inhibited by semiconductor coating

scientific article published in January 2003

Ambulatory arterial stiffness index as a predictor of blood pressure response to renal denervation

scientific article published on 20 February 2018

Amyloid plaques dissociate pentameric to monomeric C-reactive protein: a novel pathomechanism driving cortical inflammation in Alzheimer's disease?

scientific article

An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia

scientific article published on 09 June 2011

An approach towards molecular imaging of activated platelets allows imaging of symptomatic human carotid plaques in a new model of a tissue flow chamber

scientific article published on 01 March 2012

Analyzing the shear-induced sensitization of mechanosensitive ion channel Piezo-1 in human aortic endothelial cells

scientific article published on 22 September 2020

Anti-TIM-1 Monoclonal Antibody (RMT1-10) Attenuates Atherosclerosis By Expanding IgM-producing B1a Cells

scientific article published on 23 June 2018

Atherosclerotic Plaque Rupture: Identifying the Straw That Breaks the Camel's Back.

scientific article published in August 2016

B-cell-specific depletion of tumour necrosis factor alpha inhibits atherosclerosis development and plaque vulnerability to rupture by reducing cell death and inflammation.

scientific article published on 4 August 2016

Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice

scientific article published on 13 October 2011

Bio-Click Chemistry: Enzymatic Functionalization of PEGylated Capsules for Targeting Applications

scientific article published on 28 June 2012

Biomarkers for AAA: Encouraging steps but clinical relevance still to be delivered

scientific article published on 28 August 2014

C-reactive protein measurement and cardiovascular disease

scientific article published in The Lancet

C-reactive protein: how conformational changes influence inflammatory properties

scientific article published on 14 December 2009

CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages

scientific article published on 2 November 2017

CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.

scientific article published on 19 March 2007

CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies

scientific article

Cationic Nanoliposomes Meet mRNA: Efficient Delivery of Modified mRNA Using Hemocompatible and Stable Vectors for Therapeutic Applications.

scientific article published on 25 July 2017

Celastrol, a triterpene extracted from Tripterygium wilfordii Hook F, inhibits platelet activation

scientific article published in September 2009

Chip-based digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction patients.

scientific article

Circulating HtrA2 after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: A potential novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury

scientific article published in December 2017

Circulating HtrA2 as a novel biomarker for mitochondrial induced cardiomyocyte apoptosis and ischemia-reperfusion injury in ST-segment elevation myocardial infarction

scientific article published on 24 May 2017

Circulating microparticles generate and transport monomeric C-reactive protein in patients with myocardial infarction.

scientific article

Clinical proteomics: A need to define the field and to begin to set adequate standards

scientific article published on 22 January 2007

Coagulation disorders and aortic stenosis: a chicken and egg question?

scientific article published on 01 April 2013

Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice.

scientific article published on 24 March 2014

Combined blockade of ADP receptors and PI3-kinase p110β fully prevents platelet and leukocyte activation during hypothermic extracorporeal circulation

scientific article

Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets

scientific article

Construction and in vitro testing of a novel fab-hirudin-based fusion protein that targets fibrin and inhibits thrombin in a factor xa-dependent manner

scientific article published on 01 August 2003

Critical temperature ranges of hypothermia-induced platelet activation: Possible implications for cooling patients in cardiac surgery

scientific article published in April 2007

Current and future antiplatelet therapies: emphasis on preserving haemostasis

scientific article published on 3 January 2018

Cytotoxic lymphocytes and atherosclerosis: significance, mechanisms and therapeutic challenges

scientific article published on 4 May 2017

Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?

scientific article published on 4 February 2013

Destination Known: Targeted Drug Delivery in Atherosclerosis and Thrombosis

scholarly article by Erik Westein et al published 21 October 2013 in Drug Development Research

Detection of activated platelets in a mouse model of carotid artery thrombosis with 18 F-labeled single-chain antibodies

scientific article

Determining the characteristics of human atherosclerosis: A difficult but indispensable task providing the direction and proof of concept for pioneering atherosclerosis research in animal models

scientific article published on 12 June 2015

Development of a novel strategy to target CD39 antithrombotic activity to the endothelial-platelet microenvironment in kidney ischemia-reperfusion injury

scientific article published on 25 March 2017

Direct thrombin inhibition with bivalirudin as an antithrombotic strategy in general and interventional cardiology

scientific article published on August 2007

Direct thrombin inhibition with bivalirudin as an antithrombotic strategy in general and interventional cardiology

scholarly article by Ingo Ahrens et al published August 2007 in Expert Opinion on Drug Metabolism & Toxicology

Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes.

scientific article

Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

scientific article published on 11 June 2009

Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy

scientific article published on 28 April 2014

Distinct roles of ligand affinity and cytoskeletal anchorage in alphaIIbbeta3 (GP IIb/IIIa)-mediated cell aggregation and adhesion.

scientific article published in November 2004

Droplet digital PCR as a novel detection method for quantifying microRNAs in acute myocardial infarction

scientific article published on 01 April 2018

Dual targeting improves capture of ultrasound microbubbles towards activated platelets but yields no additional benefit for imaging of arterial thrombosis.

scientific article published on 2 November 2017

Dual-Targeted Theranostic Delivery of miRs Arrests Abdominal Aortic Aneurysm Development.

scientific article published on 16 February 2018

Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging

scientific article published on 20 June 2014

Effects of mutations in the cytoplasmic domain of integrin beta(1) to talin binding and cell spreading.

scientific article published on August 1999

Effects of subtotal fasting on plasmatic coagulation, fibrinolytic status and platelet activation: a controlled pilot study in healthy subjects

scientific article published in June 2005

Engineering multifunctional capsules through the assembly of metal-phenolic networks

scientific article

Engineering poly(ethylene glycol) particles for improved biodistribution

scientific article

Enzymatic antibody tagging: toward a universal biocompatible targeting tool

scientific article published on May 2012

Enzymatic single-chain antibody tagging: a universal approach to targeted molecular imaging and cell homing in cardiovascular disease

scientific article published on 23 June 2011

Enzyme-Mediated Site-Specific Bioconjugation of Metal Complexes to Proteins: Sortase-Mediated Coupling of Copper-64 to a Single-Chain Antibody

scientific article published on 28 April 2014

Evaluation of Urine Proteome Pattern Analysis for Its Potential To Reflect Coronary Artery Atherosclerosis in Symptomatic Patients

article

Evaluation of platelet activation in patients supported by the Jarvik 2000* high-rotational speed impeller ventricular assist device

scientific article published in March 2009

Evidence of a steal phenomenon by a thoracic side branch of an internal mammary artery bypass.

scientific article published in October 2006

Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target

scientific article

Ex-vivo thrombolytic gene therapy for vein graft patency: the frontier for development of selective, localised therapeutic approaches

scientific article published on 01 July 2009

Extracellular HtrA2 Induces Apoptosis in Human Umbilical Vein Endothelial Cells ⬇️

scientific article published on 31 October 2019

Forget about thrombosis: Platelets and Alzheimer's disease, yet another sticky situation

scientific article published on 24 May 2016

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research"

scientific article

GLP-1 receptor agonists: An example of the challenge for animal models to predict plaque instability/rupture and cardiovascular outcomes

scientific article published on 18 August 2017

GPIIb/IIIa inhibitors: from bench to bedside and back to bench again.

scientific article published on 28 February 2012

GPVI and GPIbα mediate staphylococcal superantigen-like protein 5 (SSL5) induced platelet activation and direct toward glycans as potential inhibitors

scientific article

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

scientific article published on 01 February 2019

Generation of activation-specific human anti-alphaMbeta2 single-chain antibodies as potential diagnostic tools and therapeutic agents

scientific article

Genetic transfer of fusion proteins effectively inhibits VCAM-1-mediated cell adhesion and transmigration via inhibition of cytoskeletal anchorage

scientific article published on January 2010

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

scientific article published on 23 July 2015

HMGB1 signals danger in acute coronary syndrome: emergence of a new risk marker for cardiovascular death?

scientific article published on 08 December 2011

High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice

scientific article published on 18 November 2010

Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets

scientific article published on 02 December 2016

Humanizing mouse thrombi

scientific article published on January 2008

Imaging monocytes with iron oxide nanoparticles targeted towards the monocyte integrin MAC-1 (CD11b/CD18) does not result in improved atherosclerotic plaque detection by in vivo MRI.

scientific article published in September 2010

Immuno-magnetoliposomes targeting activated platelets as a potentially human-compatible MRI contrast agent for targeting atherothrombosis

scientific article published on 12 March 2015

Implementation of proteomic biomarkers: making it work

scientific article

Improving selection of alphaIIbbeta3-binding phage antibodies with increased reactivity derived from immunized donors

scientific article

In vitro Study of a Novel Stent Coating Using Modified CD39 Messenger RNA to Potentially Reduce Stent Angioplasty-Associated Complications

scientific article published on 18 September 2015

In vivo detection of activated platelets allows characterizing rupture of atherosclerotic plaques with molecular magnetic resonance imaging in mice

scientific article

Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO).

scientific article published on 17 November 2016

Integrin cytoplasmic domains mediate inside-out signal transduction

scientific article

Interruption of classic CD40L-CD40 signalling but not of the novel CD40L-Mac-1 interaction limits arterial neointima formation in mice.

scientific article published on 20 March 2014

Intrinsic activating properties of GP IIb/IIIa blockers

scientific article (publication date: 30 September 2001)

Isoform-specific effects of protein phosphatase 1 on outside-in signalling of integrin αIIbβ3: a story told by genetic manipulation of platelet surrogate cells

scientific article published on 29 November 2012

Low-dose aspirin therapy is associated with improved allograft function and prolonged allograft survival after kidney transplantation

scientific article (publication date: 27 June 2004)

Lysophosphatidylcholine is a Major Component of Platelet Microvesicles Promoting Platelet Activation and Reporting Atherosclerotic Plaque Instability

scientific article published on 02 August 2019

Mac-1 directly binds to the endothelial protein C-receptor: a link between the protein C anticoagulant pathway and inflammation?

scientific article

Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis

scientific article published on 23 June 2008

Mast Cell: An Unexpected Villain in Venous Thromboembolism?

scientific article

Measuring oxidative burden and predicting pharmacological response in coronary artery disease patients with a novel direct activator of haem-free/oxidised sGC

article

Mending the failing heart

scientific article published on 01 March 2019

Mesoscale Nanoparticles: An Unexpected Means for Selective Therapeutic Targeting of Kidney Diseases!

scientific article published on 13 November 2017

Microparticles: major transport vehicles for distinct microRNAs in circulation

scientific article published on 18 January 2012

Modulation of cell adhesion by changes in alpha L beta 2 (LFA-1, CD11a/CD18) cytoplasmic domain/cytoskeleton interaction.

scientific article published on January 1995

Molecular Imaging of Activated Platelets Allows the Detection of Pulmonary Embolism with Magnetic Resonance Imaging

scientific article published on 3 May 2016

Molecular Imaging of Atherothrombotic Diseases: Seeing Is Believing

scientific article

Molecular Positron Emission Tomography in Cardiac Ischemia/Reperfusion

scientific article published on 01 March 2019

Molecular Sensors of Blood Flow in Endothelial Cells

scientific article published on 12 August 2017

Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast.

scientific article

Molecular magnetic resonance imaging allows the detection of activated platelets in a new mouse model of coronary artery thrombosis

scientific article

Monomeric C-reactive protein generation on activated platelets: the missing link between inflammation and atherothrombotic risk

scientific article published on October 2009

Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets.

scientific article published on 3 August 2015

Myeloperoxidase is a potential molecular imaging and therapeutic target for the identification and stabilization of high-risk atherosclerotic plaque

scientific article published on 01 September 2018

Myocardial Infarction-From Atherosclerosis to Thrombosis

scientific article published on 24 July 2019

Myocardial infarction caused by surgery: Blame inflammation not the surgeon

scientific article published on 01 September 2016

Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide

scientific article

Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease

scientific article

Near-infrared autofluorescence induced by intraplaque hemorrhage and heme degradation as marker for high-risk atherosclerotic plaques.

scientific article

New oral anticoagulant drugs in cardiovascular disease

scientific article published on 10 June 2010

Non-vitamin K antagonist oral anticoagulants (NOACs) in the cardiac catherisation laboratory: Friends or Foes?

scientific article published on 21 May 2015

Novel Antithrombotic Drugs on the Horizon: The Ultimate Promise to Prevent Clotting While Avoiding Bleeding

scientific article published in October 2017

Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single-Chain Antibody Specific for Activated GPIIb/IIIa

scientific article published on 3 February 2017

Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and monitoring of success or failure of thrombolysis in mice

scientific article

Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension

scientific article published on 8 September 2015

Opioids and ST Elevation Myocardial Infarction: A Systematic Review

scientific article published on 01 February 2019

Opposing effects of monomeric and pentameric C-reactive protein on endothelial progenitor cells

scientific article

Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use.

scientific article published on 11 December 2014

Patency trials with reteplase (r-PA): what do they tell us?

scientific article

Pathophysiological Levels of Soluble P-Selectin Mediate Adhesion of Leukocytes to the Endothelium Through Mac-1 Activation

scientific article published on 25 September 2008

Pentameric CRP attenuates inflammatory effects of mmLDL by inhibiting mmLDL--monocyte interactions

scientific article published on 10 August 2012

Perioperative antiplatelet therapy: A knife-edged choice between thrombosis and bleeding still based on consensus rather than evidence

article

Pharmacological inhibition of LIM kinase pathway impairs platelets functionality and facilitates thrombolysis

scientific article published on 08 June 2019

Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage and dysfunction in salt-sensitive hypertension

scientific article published on 01 March 2019

Pharmacology and clinical efficacy of reteplase

scholarly article by Christoph Bode et al published August 1997 in Fibrinolysis and Proteolysis

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

scientific article

Platelet Depletion is Effective in Ameliorating Anxiety-Like Behavior and Reducing the Pro-Inflammatory Environment in the Hippocampus in Murine Experimental Autoimmune Encephalomyelitis

scientific article published on 01 February 2019

Platelet lipidomics and function: joining the dots

scientific article published on 01 August 2018

Platelet lipidomics: a window of opportunity to assess cardiovascular risk?

scientific article published on 01 July 2017

Platelet receptors as therapeutic targets: Past, present and future

scientific article published on 8 June 2017

Platelet-Derived Microvesicles in Cardiovascular Diseases.

scientific article published on 21 November 2017

Platelet-Targeted Delivery of Peripheral Blood Mononuclear Cells to the Ischemic Heart Restores Cardiac Function after Ischemia-Reperfusion Injury

scientific article

Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis

scientific article published on 09 August 2018

Platelets Drive Inflammation and Target Gray Matter and the Retina in Autoimmune-Mediated Encephalomyelitis.

scientific article

Platelets in cardiac ischaemia/reperfusion injury: a promising therapeutic target

scientific article published on 01 June 2019

PreImplantation factor prevents atherosclerosis via its immunomodulatory effects without affecting serum lipids.

scientific article published on 4 February 2016

Prediction of acute coronary syndromes by urinary proteome analysis

scientific article

Prime time viewing of the ischaemic heart: new technologies allow imaging and flow assessment of the microvasculature in the beating heart

scientific article published on 01 November 2019

Promotion of leukocyte adhesion by a novel interaction between vitronectin and the beta2 integrin Mac-1 (alphaMbeta2, CD11b/CD18).

scientific article published on 30 September 2004

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice.

scientific article published on 16 January 2014

Proteomics unravels platelet function

scientific article published on 01 May 2010

Proton pump inhibitors, genetic polymorphisms and response to clopidogrel therapy

scientific article published on 05 May 2011

Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel

scientific article published on 01 August 2011

Recent advances in vascular biology: selected highlights from IVBM 2008

scientific article published on 01 June 2009

Recommendations for biomarker identification and qualification in clinical proteomics

scientific article published in August 2010

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

scientific article published on 12 December 2016

Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

scientific article published on 21 September 2015

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering.

scientific article

Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GPIIb/IIIa (alphaIIbbeta3, CD41/CD61).

scientific article published on 14 November 2003

Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

scientific article

Roles of Mac-1 and glycoprotein IIb/IIIa integrins in leukocyte-platelet aggregate formation: stabilization by Mac-1 and inhibition by GpIIb/IIIa blockers.

scientific article published on 6 June 2012

Selective inhibition of the platelet phosphoinositide 3-kinase p110beta as promising new strategy for platelet protection during extracorporeal circulation

scientific article published in March 2008

Selenium supplementation induces metalloproteinase-dependent L-selectin shedding from monocytes

scientific article

Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation.

scientific article published on 7 March 2017

Short-acting P2Y12 blockade to reduce platelet dysfunction and coagulopathy during experimental extracorporeal circulation and hypothermia

scientific article published on 26 February 2012

Single-chain antibodies as diagnostic tools and therapeutic agents

scientific article published on 01 June 2009

Single-chain antibodies as new antithrombotic drugs

scientific article

Single-chain antibodies for the conformation-specific blockade of activated platelet integrin alphaIIbbeta3 designed by subtractive selection from naive human phage libraries

scientific article

Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets

scientific article published on 14 July 2014

Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium

scientific article published on 23 July 2019

Staphylococcal SSL5-induced platelet microparticles provoke proinflammatory responses via the CD40/TRAF6/NFκB signalling pathway in monocytes.

scientific article published on 3 December 2015

Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose.

scientific article published in December 2012

Studying the Response of Aortic Endothelial Cells under Pulsatile Flow Using a Compact Microfluidic System

scientific article published on 22 August 2019

Subtractive single-chain antibody (scFv) phage-display: tailoring phage-display for high specificity against function-specific conformations of cell membrane molecules

scientific article

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients

scientific article published on 04 February 2019

Successful in vitro expansion and differentiation of cord blood derived CD34+ cells into early endothelial progenitor cells reveals highly differential gene expression

scientific article

Superparamagnetic iron oxide binding and uptake as imaged by magnetic resonance is mediated by the integrin receptor Mac-1 (CD11b/CD18): implications on imaging of atherosclerotic plaques.

scientific article published on 25 September 2006

Tandem Stenosis to Induce Atherosclerotic Plaque Instability in the Mouse

scientific article published in January 2015

Targeted antithrombotic protein micelles.

scientific article published on 10 December 2014

Targeting Activated Platelets: A Unique and Potentially Universal Approach for Cancer Imaging

scientific article published on 25 June 2017

Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes

scientific article

Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis: A Preclinical Pilot Study

scientific article published on 01 May 2019

Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides: comment.

scientific article published on 20 October 2017

Targeting the platelet integrin GPIIb/IIIa

scientific article published on January 2010

The Tandem Stenosis Mouse Model: Towards Understanding, Imaging and Preventing Atherosclerotic Plaque Instability and Rupture

scientific article published on 23 December 2020

The bidirectional interaction between the sympathetic nervous system and immune mechanisms in the pathogenesis of hypertension

scientific article published on 25 September 2018

The effect of oxygen in Sirt3-mediated myocardial protection: a proof-of-concept study in cultured cardiomyoblasts

scientific article published on 01 July 2018

The effects of particle size, shape, density and flow characteristics on particle margination to vascular walls in cardiovascular diseases

scientific article published on 7 April 2017

The pulmonary microvasculature entraps induced vascular progenitor cells (iVPCs) systemically delivered after cardiac ischemia-reperfusion injury: Indication for preservation of heart function via paracrine effects beyond engraftment

scientific article published on 27 August 2018

The vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response

scientific article published on 12 March 2019

The volatile anesthetic sevoflurane inhibits activation of neutrophil granulocytes during simulated extracorporeal circulation

scientific article

Therapeutic Inhibitors of Platelet Aggregation – from Aspirin to Integrin Blockersf

scientific article published in 2007

Therapeutic integrin inhibition: allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies

scientific article published on 01 May 2008

Therapeutic targeting in nanomedicine: the future lies in recombinant antibodies

scientific article

Thromboembolic and Bleeding Complications in Transcatheter Aortic Valve Implantation: Insights on Mechanisms, Prophylaxis and Therapy

scientific article published on 25 February 2019

Thrombosis and cardiovascular disease: Exciting perspectives in cardiovascular prevention and therapy

scientific article published on 13 April 2010

Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis

scientific article

Toll-Like Receptor (TLR)4 and MyD88 are Essential for Atheroprotection by Peritoneal B1a B Cells

scientific article

Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.

scientific article published on 9 February 2014

Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites

scientific article published on 23 January 2017

Urinary Proteomic Biomarkers in Coronary Artery Disease

scientific article published on 19 October 2007

Urinary proteomic diagnosis of coronary artery disease: identification and clinical validation in 623 individuals

scientific article published on November 2010

Urine proteome analysis as a discovery tool in patients with deep vein thrombosis and pulmonary embolism

scientific article

Urine proteome analysis reflects atherosclerotic disease in an ApoE-/- mouse model and allows the discovery of new candidate biomarkers in mouse and human atherosclerosis

scientific article

Veränderungen der Flüssigkeitsfiltrationskapazität und des Blutflusses nach Tourniquet bei Knieoperationen in Spinalanästhesie

Visualization of activated platelets by targeted magnetic resonance imaging utilizing conformation-specific antibodies against glycoprotein IIb/IIIa

scientific article

What matters in Cardiovascular Research? Scientific discovery driving clinical delivery

scientific article published on 01 October 2018

α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

scientific article published on 06 August 2019

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