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List of works by Tarun Jha

5-N-Substituted-2-(substituted benzenesulphonyl) glutamines as antitumor agents. Part II: synthesis, biological activity and QSAR study

scientific article published in March 2004

A new bisbenzylisoquinoline alkaloid isolated from Thalictrum foliolosum, as a potent inhibitor of DNA topoisomerase IB of Leishmania donovani

scientific article

An integrated QSAR modeling approach to explore the structure-property and selectivity relationships of N-benzoyl-L-biphenylalanines as integrin antagonists.

scientific article published on 17 November 2017

An integrated ligand-based modelling approach to explore the structure-property relationships of influenza endonuclease inhibitors

Antibacterial activity of Abies webbiana

Antineoplastic impact of leishmanial sphingolipid in tumour growth with regulation of angiogenic event and inflammatory response.

scientific article

Antitussive activity of Abies webbiana Lindl. leaf extract against sulphur dioxide-induced cough reflex in mice.

scientific article published in September 2003

Arylsulfonamides and selectivity of matrix metalloproteinase-2: An overview.

scientific article published on 10 February 2017

Binary quantitative activity-activity relationship (QAAR) studies to explore selective HDAC8 inhibitors: In light of mathematical models, DFT-based calculation and molecular dynamic simulation studies

scientific article published in 2022

Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors

scientific article published on 22 June 2020

Chemoimmunotherapeutic approach to prolonged survival time in combination with immunization and glutamic Acid derivatives with antitumor activity in tumor-bearing mice.

scientific article published in December 2007

Chemometric modeling of 5-Phenylthiophenecarboxylic acid derivatives as anti-rheumatic agents.

scientific article

Cholesteryl ester transfer protein inhibitors in coronary heart disease: Validated comparative QSAR modeling of N, N-disubstituted trifluoro-3-amino-2-propanols

scientific article published on 14 August 2013

Comparative QSAR modelling of 2-phenylindole-3-carbaldehyde derivatives as potential antimitotic agents.

scientific article published on 29 January 2009

Comparative validated molecular modeling of p53-HDM2 inhibitors as antiproliferative agents

scientific article published on 8 December 2014

Design of Aminopeptidase N Inhibitors as Anti-cancer Agents

scientific article published on 9 April 2018

Designing Potential Antitrypanosomal Thiazol-2-ethylamines through Predictive Regression Based and Classification Based QSAR Analyses.

scientific article

Designing potential HDAC3 inhibitors to improve memory and learning

scientific article published on 10 December 2018

Development of decision trees to discriminate HDAC8 inhibitors and non-inhibitors using recursive partitioning

scientific article published on 18 September 2019

Discriminations of active from inactive HDAC8 inhibitors Part II: Bayesian classification study to find molecular fingerprints

scientific article published on 19 February 2020

Essential elements regulating HDAC8 inhibition: a classification based structural analysis and enzyme-inhibitor interaction study of hydroxamate based HDAC8 inhibitors

scientific article published on 23 December 2019

Exploration of good and bad structural fingerprints for inhibition of indoleamine-2,3-dioxygenase enzyme in cancer immunotherapy using Monte Carlo optimization and Bayesian classification QSAR modeling

scientific article published on 30 May 2019

Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors ⬇️

scientific article published on January 23, 2013

Exploring QSAR and pharmacophore mapping of structurally diverse selective matrix metalloproteinase-2 inhibitors

scientific article

Exploring QSAR on 3-aminopyrazoles as antitumor agents for their inhibitory activity of CDK2/cyclin A

Exploring pyrazolo[3,4-d]pyrimidine phosphodiesterase 1 (PDE1) inhibitors: a predictive approach combining comparative validated multiple molecular modelling techniques.

scientific article published on 29 January 2017

Exploring structural requirements of 1-N-substituted thiocarbamoyl-3-phenyl-2-pyrazolines as antiamoebic agents using comparative QSAR modelling

scientific article published on 01 June 2010

Exploring structural requirements of unconventional Knoevenagel-type indole derivatives as anticancer agents through comparative QSAR modeling approaches

article

Exploring the structural aspects of ureido-amino acid-based APN inhibitors: a validated comparative multi-QSAR modelling study

scientific article published on 16 March 2020

First molecular modeling report on novel arylpyrimidine kynurenine monooxygenase inhibitors through multi-QSAR analysis against Huntington's disease: A proposal to chemists!

scientific article published in November 2016

First report on the structural exploration and prediction of new BPTES analogs as glutaminase inhibitors

article

Good and bad molecular fingerprints for human rhinovirus 3C protease inhibition: identification, validation, and application in designing of new inhibitors through Monte Carlo-based QSAR study

scientific article published on 31 January 2019

Hydroxyethylamine derivatives as HIV-1 protease inhibitors: a predictive QSAR modelling study based on Monte Carlo optimization.

scientific article published on 26 October 2017

Identification of structural fingerprints for ABCG2 inhibition by using Monte Carlo optimization, Bayesian classification, and structural and physicochemical interpretation (SPCI) analysis

scientific article published on 15 June 2020

Insight into structural features of phenyltetrazole derivatives as ABCG2 inhibitors for the treatment of multidrug resistance in cancer

scientific article published on 03 June 2019

Insight into the Structural Requirements of Theophylline-Based Aldehyde Dehydrogenase lAl (ALDHlAl) Inhibitors Through Multi-QSAR Modeling and Molecular Docking Approaches

scientific article published on 01 January 2016

Insight into the structural requirements of pyrimidine-based phosphodiesterase 10A (PDE10A) inhibitors by multiple validated 3D QSAR approaches.

scientific article published on 21 March 2017

Leishmanial lipid affords protection against oxidative stress induced hepatic injury by regulating inflammatory mediators and confining apoptosis progress

scientific article published on 23 November 2014

Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis

scientific article published on 2 April 2014

Leishmanial sphingolipid induces apoptosis in Sarcoma 180 cancer cells through regulation of tumour growth via angiogenic switchover.

scientific article published on 19 December 2014

Ligand based validated comparative chemometric modeling and pharmacophore mapping of aurone derivatives as antimalarial agents

scientific article published on September 2013

Lipid from infective L. donovani regulates acute myeloid cell growth via mitochondria dependent MAPK pathway

scientific article published on 9 March 2015

Lipid isolated from a Leishmania donovani strain reduces Escherichia coli induced sepsis in mice through inhibition of inflammatory responses

scientific article

Multiple molecular modelling studies on some derivatives and analogues of glutamic acid as matrix metalloproteinase-2 inhibitors.

scientific article published on 19 December 2017

Possible anticancer agents: QSAR analogs of glutamamide: synthesis and pharmacological activity of 1,5-N,N'-disubstituted-2-(substituted benzenesulphonyl) glutamamides.

scientific article published on 27 March 2008

QSAR modeling of neonicotinoid insecticides for their selective affinity towards Drosophila nicotinic receptors over mammalian α4β2 receptors

scholarly article by Anindya Basu et al published March 2006 in Canadian Journal of Chemistry

QSAR modeling on dopamine D2 receptor binding affinity of 6-methoxy benzamides

scientific article published in August 2005

QSAR modelling on a series of arylsulfonamide-based hydroxamates as potent MMP-2 inhibitors

scientific article published on 01 April 2019

QSAR study on some anti-HIV HEPT analogues using physicochemical and topological parameters

scientific article published in March 2004

QSAR study on some p-arylthio cinnamides as antagonists of biochemical ICAM-1/LFA-1 interaction and ICAM-1/JY-8 cell adhesion in relation to anti-inflammatory activity

scientific article published on April 2003

QSAR study on some pyridoacridine ascididemin analogues as anti-tumor agents

scientific article published on December 2003

QSAR study on the affinity of some arylpiperazines towards the 5-HT1A/alpha1-adrenergic receptor using the E-state index.

scientific article published in September 2003

Quantitative Structure-Activity Relationship Study on Some Azidopyridinyl Neonicotinoid Insecticides for Their Selective Affinity Towards the Drosophila Nicotinic Receptor Over Mammalian ?4?2 Receptor Using Electrotopological State Atom Index

scholarly article by BIKASH DEBNATH et al published 1 April 2003 in Drug design and discovery

Quantitative structure-activity relationship study on some benzodiazepine derivatives as anti-Alzheimer agents

scientific article published on 17 September 2004

Quantitative structure-activity relationship study using refractotopological state atom index on some neonicotinoid insecticides

scientific article published on December 2004

Reliable structural information for rational design of benzoxazole type potential cholesteryl ester transfer protein (CETP) inhibitors through multiple validated modeling techniques

scientific article published on 11 January 2019

Robust design of some selective matrix metalloproteinase-2 inhibitors over matrix metalloproteinase-9 through in silico/fragment-based lead identification and de novo lead modification: Syntheses and biological assays.

scientific article published on 14 July 2016

Shedding light on designing potential meprin β inhibitors through ligand-based robust validated computational approaches: A proposal to chemists!

scientific article published in September 2017

Spermicidal and contraceptive potential of desgalactotigonin: a prospective alternative of nonoxynol-9.

scientific article

Stepwise development of structure-activity relationship of diverse PARP-1 inhibitors through comparative and validated in silico modeling techniques and molecular dynamics simulation

scientific article published on 28 October 2014

Structural exploration of hydroxyethylamines as HIV-1 protease inhibitors: new features identified.

scientific article published on 23 March 2018

Structural exploration of tetrahydroisoquinoline derivatives as HDAC8 inhibitors through multi-QSAR modeling study

scientific article published on 17 May 2019

Structural findings of 2-phenylindole-3-carbaldehyde derivatives for antimitotic activity by FA-sMLR QSAR analysis.

scientific article

Structural findings of cinnolines as anti-schizophrenic PDE10A inhibitors through comparative chemometric modeling

scientific article published on 01 May 2014

Structural findings of phenylindoles as cytotoxic antimitotic agents in human breast cancer cell lines through multiple validated QSAR studies.

scientific article published on 27 May 2015

Structural refinement and prediction of potential CCR2 antagonists through validated multi-QSAR modeling studies.

scientific article published on 18 December 2017

Studies on the production and purification of an antimicrobial compound and taxonomy of the producer isolated from the marine environment of the Sundarbans.

scientific article

Synergistic effect of methanol extract of Abies webbiana leaves on sleeping time induced by standard sedatives in mice and anti-inflammatory activity of extracts in rats

scientific article published in August 2004

Synthesis, pharmacological activity and comparative QSAR modeling of 1,5-N,N'-substituted-2-(substituted naphthalenesulphonyl) glutamamides as possible anticancer agents.

scientific article

Synthesis, screening and quantitative structure-activity relationship (QSAR) studies of some glutamine analogues for possible anticancer activity.

scientific article published in July 2002

Validated predictive QSAR modeling of N-aryl-oxazolidinone-5-carboxamides for anti-HIV protease activity

scientific article published on 13 August 2010

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